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Medication: For 100 g Methyl salicylate 35 g Menthol 15 g Sodium stearate 13 g Purified water 12 g Propylene glycol 25 g What is the ratio strength of propylene glycol in this formulation? 25g / 100 g = 1:4 ratio How many grams of sodium stearate are needed to make 2.75 kg of this formulation? 13 g/ 100 g = x g / 2750 g 357.5 g A drug suspension cost $128.31 per pint. What would a week’s supply cost if a patient receives 1 tsp TID? 5mL x 3 doses/day x 7 days = 105 mL per week $128.31 / 480 mL = x / 105 mL = $28.07 A 2mL vial of tobramycin sulfate contains 80 mg of drug. How many mL of the injection should be administered to obtain 0.01 g of tobramycin sulfate? 80mg / 2mL = 10mg / x mL = 0.25 mL From the following formula, calculate the number of grams of each ingredient required to prepare 2 kg of an ointment: Precipitated sulfur 10g Salicylic acid 2g Hydrophilic ointment 88g Precipated sulfur – 10g / 100g = x / 2000g = 200g Salicylic acid – 2g / 100g = x / 2000g = 40g Hydrophilic ointment – 88g / 100g = x / 2000g = 1760g A physician orders a patient to receive 2 million units of ampicillin in a 1000 mL bag of an IV solution to be infused over 6 hours. a) How many mL of solution will the patient receive per hour? 1000mL / 6hr = x / 1 hr = 166.7mL/hr b) How many units of ampicillin will the patient receive per hour? 2,000,000 u / 6hr = x / 1 hr = 333,333 u/hr c) How many units of ampicillin will the patient receive per minute? 2,000,000 u / 6 hr = u / 60 min = x / 1 min = 5556 u/min d) What is the flow rate in mL per minute? 1000 mL/ 360 min = x / 1 min =2.78 mL/min e) How many drops per hour would the patient receive if the nurse uses an IV set that delivers 12 gtt/mL? 1000 mL / 6 hr = x / 1 hr = 166.7 mL/hr 12 gtt / mL = x / 166.7 mL = 2000 gtt/hr f) How many units of ampicillin would be used in a single drop of solution if an IV set delivering 12 gtt/mL is used? 12 gtt / 1mL = x / 1000 mL = 12,000 gtts 2,000,000 u / 12,000 gtt = x / 1 gtt =166.7 u/gtt Rx Ceclor 500mg. How many mL of a 375 mg/5 mL Ceclor oral suspension would provide the prescribed dose? 375 mg/5 mL = 500 mg / x = 6.7 mL The label on fluconazole oral suspension indicates that 24 mL of water should be added to the dry powder to make 35mL of a solution containing 10 mg/mL. a) What is the dry powder volume? Final volume – diluents = dry powder volume 35 mL – 24 mL = 11 mL b) How many grams of fluconazole would be contained in a full bottle? 10 mg / 1 mL = x / 35 mL = 350 mg = 0.35 g c) How many mL should a 48lb child receive if the package insert indicates the dose is 3 mg/kg? 1 kg = 2.2 lb = x / 48 lb 3 mg / 1 kg = x / 21.8 jg 10 mg / 1 mL = 65.4 mg / x = 21.8 kg = 65.4 mg = 6.54 or 6.5mL