Unit 6B Concept Map
Course Essential Question
Unit 6B - DNA Replication and Gene Expression
Grade Level: 10
DNA segments contain information for the production of proteins
necessary for growth and function of cells.
Subject: Biology
Unit Essential Question
Why is DNA called the “blueprint of life”?
PA Standards/Anchors/(Assessment Anchor/Eligible Content)
BIO.B.2.1, BIO.B.2.2, BIO.B.2.3
Lesson Essential Questions:
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What is the basic molecular structure of DNA?
What are the nucleotide bases in DNA and how do they
form the genetic code?
How does DNA replication differ in prokaryotic and
eukaryotic cells?
How is DNA transcribed into RNA?
What are the three types of RNA and what are their
functions in protein synthesis?
What is the process of translation? How can codons and
anticodons be used to predict amino acid sequence?
What other processes are required, beyond translation, to
form a fully functioning protein?
Which factors determine gene expression?
How are genes expressed?
Where are genes located on chromosomes?
What are the functional consequences of abnormalities
in gene expression?
How can genetic engineering benefit agriculture and
industry?
Concepts
1.
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The basic molecular and the associated genetic code
structure of DNA are universal, revolutionizing our
understanding of disease, heredity and evolution.
DNA contains the complete set of instructions, the
genetic code, for building and running an organCism.
DNA is transcribed into mRNA during gene expression.
mRNA codons pair with tRNA anticodons to determine
the amino acid sequence of proteins.
Many synthesized polypeptides require additional
processing to acquire their active, three-dimensional
structures.
Which genes are expressed at a given time is
determined by the integration of internal and
environmental signals received by a cell.
Gene expression abnormalities can result in a less
effective protein or nonfunctioning protein.
Vocabulary
1. Transformation
37. Watson
2. Bacteriophage
38. Crick
3. Base-pairing
39. Franklin
4. Replication
40. Griffith
5. DNA polymerase
6. Protein synthesis
7. Codon
8. Anticodon
9. Transcription
10. Translation
11. Selective breeding
12. Hybridization
13. Inbreeding
14. Gene splicing
15. Genetic engineering
16. Gene therapy
17. Biotechnology
18. Cloning
19. Plasmid
20. Recombinant DNA
21. DNA replication
22. RNA
23. Messenger RNA
24. Transfer RNA
25. RNA polymerase
26. Promoter
27. Intron
28. Exon
29. Mutation
30. Point mutation
31. Frameshift mutation
32. Polyploidy
33. Hox Genes
34. Hershey
35. Chase
36. Avery
-----------------------------------------------------------------Skills
1. Describe how the process of transcription
and translation are similar in all organisms.
2. Describe the role of ribosomes, endoplasmic
reticulum, Golgi apparatus, and the nucleus
in the production of specific types of
proteins
3. Describe how the genetic mutations alter the
DNA sequence and may or may not affect
phenotype (eg. Silent, nonsense, fameshift)
4. Explain how genetic engineering has
impacted the fields of medicine, forensics,
and agriculture ( e.g. selective breeding,
gene splicing, cloning, genetically modified
organisms, gene therapy)
5. Predict how errors in replication,
transcription, and translation will affect
gene expression.
Formative Assessments Summative Assessments
1. Ticket out the
1. Quizzes
door
2. Unit Tests:
2. Think-pair-share
 Test 1 – DNA
3. Thumbs up –
 Test 2 - RNA
Thumbs down
3. Labs:
4. Concept Map
 Extracting DNA –
5. Sentence starter
PH Lab manual
prompts
#12
6. Collins writing
 DNA to Protein
7. Venn diagram
Synthesis – PH
8. Compare
Lab manual #13
contrast
 DNA to Solve
9. 3-2-1
Crimes – PH Lab
10. Frayer diagrams
manual #15
11. KWL
4. Activities:
12. Whiteboard
 Modeling DNA
responses
Replication (hands
on #11)
 GM Crops in the
United States (Data
analysis #20)
 Base Percentages
(Data analysis #17)
5. Projects
6. CDT biology
Resources
Biology textbook
Powerpoints (from textbook resources)
Biology websites:
-biologyjunction.com
-biologycorner.com
-biology.com