CURRICULUM VITAE

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1.
Zhang B, Ramonell K, Somerville S, Stacey G. Characterization of early, chitin-induced
gene expression in Arabidopsis. Mol Plant Microbe Interact. 15(9): 963-70, 2002. PMID:
12236603.
2.
Ramonell KM, Zhang B, Ewing RM, Chen Y, Xu D, Stacey G, Somerville S. Microarray
analysis of chitin elicitation in Arabidopsis thaliana. Mol Plant Pathol. 3(5): 301-11,
2002. PMID: 20569338.
3.
Zhang B, Schmoyer D, Kirov S, Snoddy J. GOTree Machine (GOTM): a web-based
platform for interpreting sets of interesting genes using Gene Ontology hierarchies. BMC
Bioinformatics. 5:16, 2004. PMID: 14975175; PMCID: PMC373441.
4.
Urs S, Smith C, Campbell B, Saxton AM, Taylor J, Zhang B, Snoddy J, Jones Voy B,
Moustaid-Moussa N. Gene expression profiling in human preadipocytes and adipocytes
by microarray analysis. J Nutr. 134(4): 762-70, 2004. PMID: 15051823.
5.
Zhang B, Kirov S, Snoddy J. WebGestalt: an integrated system for exploring gene sets in
various biological contexts. Nucleic Acids Res. 33(Web Server issue): W741-8, 2005.
PMID: 15980575; PMCID: PMC1160236.
6.
Kirov SA, Peng X, Baker E, Schmoyer D, Zhang B, Snoddy J. GeneKeyDB: a
lightweight, gene-centric, relational database to support data mining environments. BMC
Bioinformatics. 6: 72, 2005. PMID: 15790402; PMCID: PMC1274265.
7.
Baldwin NE, Chesler EJ, Kirov S, Langston MA, Snoddy JR, Williams RW, Zhang B.
Computational, integrative, and comparative methods for the elucidation of genetic
coexpression networks. J Biomed Biotechnol. 2005(2): 172-80, 2005. PMID: 16046823;
PMCID: PMC1184052.
8.
Zhang B, VerBerkmoes NC, Langston MA, Uberbacher E, Hettich RL, Samatova NF.
Detecting differential and correlated protein expression in label-free shotgun proteomics.
J Proteome Res. 5(11): 2909-18, 2006. PMID: 17081042.
9.
Kirov SA, Zhang B, Snoddy JR. Association analysis for large-scale gene set data.
Methods Mol Biol. 408: 19-33, 2006. PMID: 18314575.
10.
Zhang B, Chambers MC, Tabb DL. Proteomic parsimony through bipartite graph
analysis improves accuracy and transparency. J Proteome Res. 6(9): 3549-57, 2007.
PMID: 17676885; PMCID: PMC2810678.
11.
Zhang B, Park BH, Karpinets T, Samatova NF. From pull-down data to protein
interaction networks and complexes with biological relevance. Bioinformatics. 24(7):
979-86, 2008. PMID: 18304937.
12.
Pan C, Oda Y, Lankford PK, Zhang B, Samatova NF, Pelletier DA, Harwood CS,
Hettich RL. Characterization of anaerobic catabolism of p-coumarate in
Rhodopseudomonas palustris by integrating transcriptomics and quantitative proteomics.
Mol Cell Proteomics. 7(5): 938-48, 2008. PMID: 18156135.
13.
Wilmes P, Andersson AF, Lefsrud MG, Wexler M, Shah M, Zhang B, Hettich RL, Bond
PL, VerBerkmoes NC, Banfield JF. Community proteogenomics highlights microbial
strain-variant protein expression within activated sludge performing enhanced biological
phosphorus removal. ISME J. 2(8): 853-64, 2008. PMID: 18449217.
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14.
Chen X, Wang L, Smith JD, Zhang B. Supervised principal component analysis for gene
set enrichment of microarray data with continuous or survival outcomes. Bioinformatics.
24(21): 2474-81, 2008. PMID: 18753155; PMCID: PMC2732277.
15.
Wang L, Zhang B, Wolfinger RD, Chen X. An integrated approach for the analysis of
biological pathways using mixed models. PLoS Genet. 4(7): e1000115, 2008. PMID:
18852846; PMCID: PMC2565842.
16.
Wang L, Chen X, Wolfinger RD, Franklin JL, Coffey RJ, Zhang B. A unified mixed
effects model for gene set analysis of time course microarray experiments. Stat Appl
Genet Mol Biol. 8(1):Article 47, 2009. PMID: 19954419; PMCID: PMC2861317.
17.
Li J, Zimmerman LJ, Park BH, Tabb DL, Liebler DC, Zhang B. Network-assisted
protein identification and data interpretation in shotgun proteomics. Mol Syst Biol. 5: 303,
2009. PMID: 19690572; PMCID: PMC2736651.
18.
Chourey K, Thompson MR, Shah M, Zhang B, Verberkmoes NC, Thompson DK,
Hettich RL. Comparative temporal proteomics of a response regulator (SO2426)deficient strain and wild-type Shewanella oneidensis MR-1 during chromate
transformation. J Proteome Res. 8(1): 59-71, 2009. PMID: 19118451.
19.
Unell M, Abraham P, Shah M, Zhang B, Rückert C, Verberkmoes N, Jansson J. Impact
of Phenolic Substrate and Growth Temperature on the Arthrobacter chlorophenolicus
Proteome. J Proteome Res. 8(4): 1953-64, 2009. PMID: 19216575.
20.
Codreanu SG, Zhang B, Sobecki SM, Billheimer DD, Liebler DC. Global analysis of
protein damage by the lipid electrophile 4-hydroxy-2-nonenal. Mol Cell Proteomics. 8(4):
670-80, 2009. PMID: 19054759; PMCID: PMC2667350.
21.
Gerlee P, Lundh T, Zhang B, Anderson AR. Gene divergence and pathway duplication
in the metabolic network of yeast and digital organisms. J R Soc Interface. 6(41): 123345, 2009. PMID: 19324678; PMCID: PMC2817152.
22.
Ball HL, Zhang B, Riches JJ, Gandhi R, Li J, Rommens JM, Myers JS. ShwachmanBodian Diamond syndrome is a multi-functional protein implicated in cellular stress
responses. Hum Mol Genet. 18(19): 3684-95, 2009. PMID: 19602484; PMCID:
PMC2742402.
23.
Li J, Duncan DT, Zhang B. CanProVar: a human cancer proteome variation database.
Hum Mutat. 31(3): 219-28, 2010. PMID: 20052754; PMCID: PMC2829365.
24.
Smith JJ, Deane NG, Wu F, Merchant NB, Zhang B, Jiang A, Lu P, Johnson JC,
Schmidt C, Bailey CE, Eschrich S, Kis C, Levy S, Washington MK, Heslin MJ, Coffey
RJ, Yeatman TJ, Shyr Y, Beauchamp RD. Experimentally derived metastasis gene
expression profile predicts recurrence and death in patients with colon cancer.
Gastroenterology. 138(3): 958-68, 2010. PMID: 19914252.
25.
Wylie CJ, Hendricks TJ, Zhang B, Wang L, Lu P, Leahy P, Fox S, Maeno H, Deneris
ES. Distinct transcriptomes define rostral and caudal serotonin neurons. J Neurosci.
30(2): 670-84, 2010. PMID: 20071532.
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26.
Morabito MV, Ulbricht RJ, O'Neil RT, Airey DC, Lu P, Zhang B, Wang L, Emeson RB.
High-throughput multiplexed transcript analysis yields enhanced resolution of 5hydroxytryptamine 2C receptor mRNA editing profiles. Mol Pharmacol. 77(6): 895-902,
2010. PMID: 20181818; PMCID: PMC2879922.
27.
Thompson DK, Chourey K, Wickham GS, Thieman SB, VerBerkmoes NC, Zhang B,
McCarthy AT, Rudisill MA, Shah M, Hettich RL. Proteomics reveals a core molecular
response of Pseudomonas putida F1 to acute chromate challenge. BMC Genomics.
11:311, 2010. PMID: 20482812; PMCID: PMC2996968.
28.
Shi Z, Derow CK, Zhang B. Co-expression module analysis reveals biological processes,
genomic gain, and regulatory mechanisms associated with breast cancer progression.
BMC Syst Biol. 4:74, 2010. PMID: 20507583; PMCID: PMC2902438.
29.
Angel PM, Nusinow D, Brown CB, Violette K, Barnett JV, Zhang B, Baldwin HS,
Caprioli RM. Networked-based Characterization of Extracellular Matrix Proteins from
Adult Mouse Pulmonary and Aortic Valves. J Proteome Res. 10(2):812-823, 2011.
PMID: 21133377.
30.
Lu H, Wang X, Pullen M, Guan H, Chen H, Sahu S, Zhang B, Chen H, Williams RW,
Geisert EE, Lu L, Jablonski MM. Genetic Dissection of the Gpnmb Network in the Eye.
Invest Ophthalmol Vis Sci. 52(7):4132-42, 2011. PMID: 21398278.
31.
Li J, Su Z, Ma ZQ, Slebos RJ, Halvey P, Tabb DL, Liebler DC, Pao W, Zhang B. A
bioinformatics workflow for variant peptide detection in shotgun proteomics. Mol Cell
Proteomics. 10(5):M110.006536, 2011. PMID: 21389108.
32.
Shi Z, Zhang B. Fast network centrality analysis using GPUs. BMC Bioinformatics.
12:149, 2011. PMID: 21569426. PMCID: PMC3115853.
33.
Zhang B, Shi Z, Duncan DT, Prodduturi N, Marnett LJ, Liebler DC. Relating protein
adduction to gene expression changes: a systems approach. Mol Biosyst. 7(7):2118-27,
2011. PMID: 21594272.
34.
Shi M, Zhang B. Semi-supervised learning improves gene expression-based prediction of
cancer recurrence. Bioinformatics. 27:3017-3023, 2011. PMID: 21893520. PMCID:
PMC3198572.
35.
Halvey PJ, Zhang B, Coffey R, Liebler DC, Slebos RJC. Proteomic consequences of a
single gene mutation in a colorectal cancer model. J Proteome Res. 11:1184-1195, 2012.
PMID: 22103262. PMCID: PMC3271737.
36.
Liu Q, Guo Y, Li J, Long J, Zhang B, Shyr Y. Steps to ensure accuracy in genotype and
SNP calling from Illumina sequencing data. BMC Genomics. 13(Suppl 8):S8, 2012.
PMID: 23281772. PMCID: PMC3535703.
37.
Sousa JF, Ham AL, Whitwell C, Nam KT, Lee HJ, Yang HK, Kim WH, Zhang B, Li M,
LaFleur B, Liebler D, Goldenring JR. Proteomic profiling of metaplasia and cancer in the
human stomach reveals metaplasia-specific biomarkers. Am J Pathol. 181(5):1560-72,
2012. PMID: 22944598. PMCID: PMC3483808.
38.
Hardaway JA, Hardie SL, Whitaker SM, Baas SR, Zhang B, Bermingham DP,
LichtensteinAJ, Blakely RD. Forward genetic analysis to identify presynaptic
determinants of dopamine signaling in Caenorhabditis elegans using swimming-induced
3
paralysis. G3. 2(8): 961–975, 2012. PMID: 22908044. PMCID: PMC3411251.
39.
Wang L, Chen X, Zhang B. Statistical analysis of patient-specific pathway activities via
mixed models. J Biomet Biostat. S8:001, 2012.
40.
Jourquin J, Duncan D, Zhang B. GLAD4U: deriving and prioritizing gene lists from
PubMed literature. BMC Genomics. 13(Suppl 8):S20, 2012. PMID: 23282288. PMCID:
PMC3535723.
41.
Hoshino D, Jourquin J, Emmons SW, Miller T, Goldgof M, Costello K, Tyson DR,
Brown B, Prasad NK, Zhang B, Mills GB, Yarbrough WG, Quaranta V, Seiki M,
Weaver AM. Network analysis of the focal adhesion-invadopodia transition identifies a
PI 3-kinase-PKCalpha invasive signaling axis. Sci Signal. 5(241):ra66, 2012. PMID:
22969158. PMCID: PMC3583194.
42.
Wang X, Slebos RJC, Wang D, Halvey PJ, Tabb DL, Liebler DC, Zhang B. Protein
identification using customized protein sequence databases derived from RNA-Seq data.
J Proteome Res. 11:1009-1017, 2012. PMID: 22103967.
43.
Shi M, Beauchamp RD, Zhang B. A network-based gene expression signature informs
prognosis and treatment for colorectal cancer patients. PLoS One. 7(7):e41292, 2012.
PMID: 22844451. PMCID: PMC3402487.
44.
Al-Greene NT, Means AL, Lu P, Jiang A, Schmidt CR, Chakravarthy AB, Merchant NB,
Washington MK, Zhang B, Shyr Y, Deane NG, Beauchamp RD. Four jointed box 1
promotes angiogenesis and is associated with poor patient survival in colorectal
carcinoma. PLoS One. 8(7):e69660, 2013. PMID: 23922772. PMCID: PMC3726759.
45.
Franklin JL, Rankin CR, Levy S, Snoddy JR, Zhang B, Washington MK, Michael TJ,
Whitehead RH, Coffey RJ. Malignant transformation of colonic epithelial cells by a
colon-derived long noncoding RNA. Biochem Biophys Res Commun, 44:99-104, 2013.
PMID: 24045012. PMCID: PMC3875348.
46.
Chen YY, Chambers MC, Li M, Ham AJ, Turner JL, Zhang B, Tabb DL. IDPQuantify:
Combining Precursor Intensity with Spectral Counts for Protein and Peptide
Quantification. J Proteome Res. 12:4111-4121, 2013. PMID: 23879310.
47.
Wang J, Qian J, Hoeksema MD, Zou Y, Espinosa AV, Rahman JS, Zhang B*, Massion
PP*. Integrative genomics analysis identifies candidate drivers at 3q26-29 amplicon in
squamous cell carcinoma of the lung. Clin Cancer Res. 19:5580-5590, 2013. PMID:
23908357. (*co-corresponding authors)
48.
Liu Q, Ullery J, Zhu J, Liebler DC, Marnett LJ, Zhang B. RNA-Seq data analysis at the
gene and CDS levels provides a compreshnsive view of transcriptome responses induced
by 4-hydroxynonenal. Mol Biosyst, 9:3036-3046, 2013. PMID: 24056865.
49.
Zhu J, Wang J, Shi Z, Franklin J, Deane N, Coffey RJ, Beauchamp RD, Zhang B.
Deciphering genomic alterations in colorectal cancer through transcriptional subtypebased network analysis. PLoS One, 8:e79282, 2013. PMID: 24260186.
50.
Wang X, Zhang B. customProDB: an R package for generating customized protein
databases from next generation sequencing data. Bioinformatics, 29:3235-3237, 2013.
PMID: 24058055.
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51.
Liu Q, Halvey PJ, Shyr Y, Slebos RJC, Liebler DC, Zhang B. Dissecting microRNAmediated regulation through integrative transcriptomics and proteomics analysis. Mol
Cell Proteomics, 12(7):1900-1911, 2013. PMID: 23550052.
52.
Wang J, Duncan D, Shi Z, Zhang B. WEB-based Gene SeT AnaLysis Toolkit
(WebGestalt): update 2013. Nucleic Acids Res, 41(Web Serve issue):W77-83, 2013.
PMID: 23701235.
53.
Shi Z, Wang J, Zhang B. NetGestalt: integrating multidimensional omics data over
biological networks. Nature Methods, 10(7):597-598, 2013. PMID: 23807191.
54.
Zhu X, Liang J, Shrubsole MJ, Ness RM, Cai Q, Long J, Chen Z, Li G, Wiese D, Zhang
B, Smalley WE, Edwards TL, Giovannucci E, Zheng W, Dai Q. Calcium Intake and Ion
Transporter Genetic Polymorphisms Interact in Human Colorectal Neoplasia Risk in a 2Phase Study. J Nutr., in press, 2014. PMID: 25165391.
55.
Hardaway JA, Wang J, Fleming PA, Fleming KA, Whitaker SM, Nackenoff A,
Snarrenberg CL, Hardie SL, Zhang B, Blakely RD. An open-source analytical platform
for analysis of C. elegans swimming-induced paralysis. J Neurosci Methods, 232:58-62,
2014. PMID: 24792527; PMCID: PMC4179448.
56.
Ye R, Carneiro AM, Han Q, Airey D, Sanders-Bush E, Zhang B, Lu L, Williams RW,
Blakely RD. Quantitative Trait Loci Mapping and Gene Network Analysis Implicate
Protocadherin-15 as A Determinant of Brain Serotonin Transporter Expression. Genes
Brain Behav, 13:261-275, 2014. PMID: 24405699.
57.
Ye R, Carneiro AM, Airey D, Sanders-Bush E, Williams RW, Lu L, Wang J, Zhang B,
Blakely RD. Evaluation of heritable determinants of blood and brain serotonin
homeostasis using recombinant inbred mice. Genes Brain Behav, 13:247-260, 2014.
PMID: 24102824.
58.
Halvey PJ, Wang X, Wang J, Bhat AA, Dhawan P, Li M, Zhang B, Liebler DC, Slebos
RJ. Proteomic analysis reveals unanticipated adaptation of colorectal tumor cells to
deficiencies in DNA mismatch repair. Cancer Res. 74:387-397, 2014. PMID: 24247723.
59.
Codreanu SG, Ullery JC, Zhu J, Tallman KA, Beavers WN, Porter NA, Marnett LJ,
Zhang B, Liebler DC. Alkylation damage by lipid electrophiles targets functional protein
systems. Mol Cell Proteomics, 13:849-859, 2014. PMID: 24429493.
60.
Tripathi MK, Deane NG, Zhu J, An H, Mima S, Wang X, Padmanabhan S, Shi Z,
Prodduturi N, Ciombor KK, Chen X, Washington MK, Zhang B*, Beauchamp RD*.
Nuclear factor of activated T-cell activity is associated with metastatic capacity in colon
cancer. Cancer Res., 74(23):6947-57, 2014. PMID: 25320007. (* co-corresponding
authors).
61.
Wang X, Zhang B. Integrating genomic, transcriptomic and interactome data to improve
peptide and protein identification in shotgun proteomics. J Proteome Res., 13:2715-2723,
2014.
62.
Wang X, Liu Q, Zhang B. Leveraging the complementary nature of RNA-Seq and
shotgun proteomics data. Proteomics, 14:2676-2687, 2014. PMID: 25266668.
63.
Zhu J, Shi Z, Wang J, Zhang B. Empowering biologists with multi-omics data: colorectal
cancer as a paradigm. Bioinformatics, in press, 2014. PMID: 25527095.
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64.
Zhang B, Wang J, Wang X, Zhu J, Liu Q, Shi Z, Chambers MC, Zimmerman LJ,
Shaddox KF, Tabb DL Slebos RJC, Liebler D and the NCI CPTAC Network.
Proteogenomic characterization of human colon and rectal cancer. Nature, 513:382-387,
2014. PMID: 25043054
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