1. Zhang B, Ramonell K, Somerville S, Stacey G. Characterization of early, chitin-induced gene expression in Arabidopsis. Mol Plant Microbe Interact. 15(9): 963-70, 2002. PMID: 12236603. 2. Ramonell KM, Zhang B, Ewing RM, Chen Y, Xu D, Stacey G, Somerville S. Microarray analysis of chitin elicitation in Arabidopsis thaliana. Mol Plant Pathol. 3(5): 301-11, 2002. PMID: 20569338. 3. Zhang B, Schmoyer D, Kirov S, Snoddy J. GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies. BMC Bioinformatics. 5:16, 2004. PMID: 14975175; PMCID: PMC373441. 4. Urs S, Smith C, Campbell B, Saxton AM, Taylor J, Zhang B, Snoddy J, Jones Voy B, Moustaid-Moussa N. Gene expression profiling in human preadipocytes and adipocytes by microarray analysis. J Nutr. 134(4): 762-70, 2004. PMID: 15051823. 5. Zhang B, Kirov S, Snoddy J. WebGestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic Acids Res. 33(Web Server issue): W741-8, 2005. PMID: 15980575; PMCID: PMC1160236. 6. Kirov SA, Peng X, Baker E, Schmoyer D, Zhang B, Snoddy J. GeneKeyDB: a lightweight, gene-centric, relational database to support data mining environments. BMC Bioinformatics. 6: 72, 2005. PMID: 15790402; PMCID: PMC1274265. 7. Baldwin NE, Chesler EJ, Kirov S, Langston MA, Snoddy JR, Williams RW, Zhang B. Computational, integrative, and comparative methods for the elucidation of genetic coexpression networks. J Biomed Biotechnol. 2005(2): 172-80, 2005. PMID: 16046823; PMCID: PMC1184052. 8. Zhang B, VerBerkmoes NC, Langston MA, Uberbacher E, Hettich RL, Samatova NF. Detecting differential and correlated protein expression in label-free shotgun proteomics. J Proteome Res. 5(11): 2909-18, 2006. PMID: 17081042. 9. Kirov SA, Zhang B, Snoddy JR. Association analysis for large-scale gene set data. Methods Mol Biol. 408: 19-33, 2006. PMID: 18314575. 10. Zhang B, Chambers MC, Tabb DL. Proteomic parsimony through bipartite graph analysis improves accuracy and transparency. J Proteome Res. 6(9): 3549-57, 2007. PMID: 17676885; PMCID: PMC2810678. 11. Zhang B, Park BH, Karpinets T, Samatova NF. From pull-down data to protein interaction networks and complexes with biological relevance. Bioinformatics. 24(7): 979-86, 2008. PMID: 18304937. 12. Pan C, Oda Y, Lankford PK, Zhang B, Samatova NF, Pelletier DA, Harwood CS, Hettich RL. Characterization of anaerobic catabolism of p-coumarate in Rhodopseudomonas palustris by integrating transcriptomics and quantitative proteomics. Mol Cell Proteomics. 7(5): 938-48, 2008. PMID: 18156135. 13. Wilmes P, Andersson AF, Lefsrud MG, Wexler M, Shah M, Zhang B, Hettich RL, Bond PL, VerBerkmoes NC, Banfield JF. Community proteogenomics highlights microbial strain-variant protein expression within activated sludge performing enhanced biological phosphorus removal. ISME J. 2(8): 853-64, 2008. PMID: 18449217. 1 14. Chen X, Wang L, Smith JD, Zhang B. Supervised principal component analysis for gene set enrichment of microarray data with continuous or survival outcomes. Bioinformatics. 24(21): 2474-81, 2008. PMID: 18753155; PMCID: PMC2732277. 15. Wang L, Zhang B, Wolfinger RD, Chen X. An integrated approach for the analysis of biological pathways using mixed models. PLoS Genet. 4(7): e1000115, 2008. PMID: 18852846; PMCID: PMC2565842. 16. Wang L, Chen X, Wolfinger RD, Franklin JL, Coffey RJ, Zhang B. A unified mixed effects model for gene set analysis of time course microarray experiments. Stat Appl Genet Mol Biol. 8(1):Article 47, 2009. PMID: 19954419; PMCID: PMC2861317. 17. Li J, Zimmerman LJ, Park BH, Tabb DL, Liebler DC, Zhang B. Network-assisted protein identification and data interpretation in shotgun proteomics. Mol Syst Biol. 5: 303, 2009. PMID: 19690572; PMCID: PMC2736651. 18. Chourey K, Thompson MR, Shah M, Zhang B, Verberkmoes NC, Thompson DK, Hettich RL. Comparative temporal proteomics of a response regulator (SO2426)deficient strain and wild-type Shewanella oneidensis MR-1 during chromate transformation. J Proteome Res. 8(1): 59-71, 2009. PMID: 19118451. 19. Unell M, Abraham P, Shah M, Zhang B, Rückert C, Verberkmoes N, Jansson J. Impact of Phenolic Substrate and Growth Temperature on the Arthrobacter chlorophenolicus Proteome. J Proteome Res. 8(4): 1953-64, 2009. PMID: 19216575. 20. Codreanu SG, Zhang B, Sobecki SM, Billheimer DD, Liebler DC. Global analysis of protein damage by the lipid electrophile 4-hydroxy-2-nonenal. Mol Cell Proteomics. 8(4): 670-80, 2009. PMID: 19054759; PMCID: PMC2667350. 21. Gerlee P, Lundh T, Zhang B, Anderson AR. Gene divergence and pathway duplication in the metabolic network of yeast and digital organisms. J R Soc Interface. 6(41): 123345, 2009. PMID: 19324678; PMCID: PMC2817152. 22. Ball HL, Zhang B, Riches JJ, Gandhi R, Li J, Rommens JM, Myers JS. ShwachmanBodian Diamond syndrome is a multi-functional protein implicated in cellular stress responses. Hum Mol Genet. 18(19): 3684-95, 2009. PMID: 19602484; PMCID: PMC2742402. 23. Li J, Duncan DT, Zhang B. CanProVar: a human cancer proteome variation database. Hum Mutat. 31(3): 219-28, 2010. PMID: 20052754; PMCID: PMC2829365. 24. Smith JJ, Deane NG, Wu F, Merchant NB, Zhang B, Jiang A, Lu P, Johnson JC, Schmidt C, Bailey CE, Eschrich S, Kis C, Levy S, Washington MK, Heslin MJ, Coffey RJ, Yeatman TJ, Shyr Y, Beauchamp RD. Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer. Gastroenterology. 138(3): 958-68, 2010. PMID: 19914252. 25. Wylie CJ, Hendricks TJ, Zhang B, Wang L, Lu P, Leahy P, Fox S, Maeno H, Deneris ES. Distinct transcriptomes define rostral and caudal serotonin neurons. J Neurosci. 30(2): 670-84, 2010. PMID: 20071532. 2 26. Morabito MV, Ulbricht RJ, O'Neil RT, Airey DC, Lu P, Zhang B, Wang L, Emeson RB. High-throughput multiplexed transcript analysis yields enhanced resolution of 5hydroxytryptamine 2C receptor mRNA editing profiles. Mol Pharmacol. 77(6): 895-902, 2010. PMID: 20181818; PMCID: PMC2879922. 27. Thompson DK, Chourey K, Wickham GS, Thieman SB, VerBerkmoes NC, Zhang B, McCarthy AT, Rudisill MA, Shah M, Hettich RL. Proteomics reveals a core molecular response of Pseudomonas putida F1 to acute chromate challenge. BMC Genomics. 11:311, 2010. PMID: 20482812; PMCID: PMC2996968. 28. Shi Z, Derow CK, Zhang B. Co-expression module analysis reveals biological processes, genomic gain, and regulatory mechanisms associated with breast cancer progression. BMC Syst Biol. 4:74, 2010. PMID: 20507583; PMCID: PMC2902438. 29. Angel PM, Nusinow D, Brown CB, Violette K, Barnett JV, Zhang B, Baldwin HS, Caprioli RM. Networked-based Characterization of Extracellular Matrix Proteins from Adult Mouse Pulmonary and Aortic Valves. J Proteome Res. 10(2):812-823, 2011. PMID: 21133377. 30. Lu H, Wang X, Pullen M, Guan H, Chen H, Sahu S, Zhang B, Chen H, Williams RW, Geisert EE, Lu L, Jablonski MM. Genetic Dissection of the Gpnmb Network in the Eye. Invest Ophthalmol Vis Sci. 52(7):4132-42, 2011. PMID: 21398278. 31. Li J, Su Z, Ma ZQ, Slebos RJ, Halvey P, Tabb DL, Liebler DC, Pao W, Zhang B. A bioinformatics workflow for variant peptide detection in shotgun proteomics. Mol Cell Proteomics. 10(5):M110.006536, 2011. PMID: 21389108. 32. Shi Z, Zhang B. Fast network centrality analysis using GPUs. BMC Bioinformatics. 12:149, 2011. PMID: 21569426. PMCID: PMC3115853. 33. Zhang B, Shi Z, Duncan DT, Prodduturi N, Marnett LJ, Liebler DC. Relating protein adduction to gene expression changes: a systems approach. Mol Biosyst. 7(7):2118-27, 2011. PMID: 21594272. 34. Shi M, Zhang B. Semi-supervised learning improves gene expression-based prediction of cancer recurrence. Bioinformatics. 27:3017-3023, 2011. PMID: 21893520. PMCID: PMC3198572. 35. Halvey PJ, Zhang B, Coffey R, Liebler DC, Slebos RJC. Proteomic consequences of a single gene mutation in a colorectal cancer model. J Proteome Res. 11:1184-1195, 2012. PMID: 22103262. PMCID: PMC3271737. 36. Liu Q, Guo Y, Li J, Long J, Zhang B, Shyr Y. Steps to ensure accuracy in genotype and SNP calling from Illumina sequencing data. BMC Genomics. 13(Suppl 8):S8, 2012. PMID: 23281772. PMCID: PMC3535703. 37. Sousa JF, Ham AL, Whitwell C, Nam KT, Lee HJ, Yang HK, Kim WH, Zhang B, Li M, LaFleur B, Liebler D, Goldenring JR. Proteomic profiling of metaplasia and cancer in the human stomach reveals metaplasia-specific biomarkers. Am J Pathol. 181(5):1560-72, 2012. PMID: 22944598. PMCID: PMC3483808. 38. Hardaway JA, Hardie SL, Whitaker SM, Baas SR, Zhang B, Bermingham DP, LichtensteinAJ, Blakely RD. Forward genetic analysis to identify presynaptic determinants of dopamine signaling in Caenorhabditis elegans using swimming-induced 3 paralysis. G3. 2(8): 961–975, 2012. PMID: 22908044. PMCID: PMC3411251. 39. Wang L, Chen X, Zhang B. Statistical analysis of patient-specific pathway activities via mixed models. J Biomet Biostat. S8:001, 2012. 40. Jourquin J, Duncan D, Zhang B. GLAD4U: deriving and prioritizing gene lists from PubMed literature. BMC Genomics. 13(Suppl 8):S20, 2012. PMID: 23282288. PMCID: PMC3535723. 41. Hoshino D, Jourquin J, Emmons SW, Miller T, Goldgof M, Costello K, Tyson DR, Brown B, Prasad NK, Zhang B, Mills GB, Yarbrough WG, Quaranta V, Seiki M, Weaver AM. Network analysis of the focal adhesion-invadopodia transition identifies a PI 3-kinase-PKCalpha invasive signaling axis. Sci Signal. 5(241):ra66, 2012. PMID: 22969158. PMCID: PMC3583194. 42. Wang X, Slebos RJC, Wang D, Halvey PJ, Tabb DL, Liebler DC, Zhang B. Protein identification using customized protein sequence databases derived from RNA-Seq data. J Proteome Res. 11:1009-1017, 2012. PMID: 22103967. 43. Shi M, Beauchamp RD, Zhang B. A network-based gene expression signature informs prognosis and treatment for colorectal cancer patients. PLoS One. 7(7):e41292, 2012. PMID: 22844451. PMCID: PMC3402487. 44. Al-Greene NT, Means AL, Lu P, Jiang A, Schmidt CR, Chakravarthy AB, Merchant NB, Washington MK, Zhang B, Shyr Y, Deane NG, Beauchamp RD. Four jointed box 1 promotes angiogenesis and is associated with poor patient survival in colorectal carcinoma. PLoS One. 8(7):e69660, 2013. PMID: 23922772. PMCID: PMC3726759. 45. Franklin JL, Rankin CR, Levy S, Snoddy JR, Zhang B, Washington MK, Michael TJ, Whitehead RH, Coffey RJ. Malignant transformation of colonic epithelial cells by a colon-derived long noncoding RNA. Biochem Biophys Res Commun, 44:99-104, 2013. PMID: 24045012. PMCID: PMC3875348. 46. Chen YY, Chambers MC, Li M, Ham AJ, Turner JL, Zhang B, Tabb DL. IDPQuantify: Combining Precursor Intensity with Spectral Counts for Protein and Peptide Quantification. J Proteome Res. 12:4111-4121, 2013. PMID: 23879310. 47. Wang J, Qian J, Hoeksema MD, Zou Y, Espinosa AV, Rahman JS, Zhang B*, Massion PP*. Integrative genomics analysis identifies candidate drivers at 3q26-29 amplicon in squamous cell carcinoma of the lung. Clin Cancer Res. 19:5580-5590, 2013. PMID: 23908357. (*co-corresponding authors) 48. Liu Q, Ullery J, Zhu J, Liebler DC, Marnett LJ, Zhang B. RNA-Seq data analysis at the gene and CDS levels provides a compreshnsive view of transcriptome responses induced by 4-hydroxynonenal. Mol Biosyst, 9:3036-3046, 2013. PMID: 24056865. 49. Zhu J, Wang J, Shi Z, Franklin J, Deane N, Coffey RJ, Beauchamp RD, Zhang B. Deciphering genomic alterations in colorectal cancer through transcriptional subtypebased network analysis. PLoS One, 8:e79282, 2013. PMID: 24260186. 50. Wang X, Zhang B. customProDB: an R package for generating customized protein databases from next generation sequencing data. Bioinformatics, 29:3235-3237, 2013. PMID: 24058055. 4 51. Liu Q, Halvey PJ, Shyr Y, Slebos RJC, Liebler DC, Zhang B. Dissecting microRNAmediated regulation through integrative transcriptomics and proteomics analysis. Mol Cell Proteomics, 12(7):1900-1911, 2013. PMID: 23550052. 52. Wang J, Duncan D, Shi Z, Zhang B. WEB-based Gene SeT AnaLysis Toolkit (WebGestalt): update 2013. Nucleic Acids Res, 41(Web Serve issue):W77-83, 2013. PMID: 23701235. 53. Shi Z, Wang J, Zhang B. NetGestalt: integrating multidimensional omics data over biological networks. Nature Methods, 10(7):597-598, 2013. PMID: 23807191. 54. Zhu X, Liang J, Shrubsole MJ, Ness RM, Cai Q, Long J, Chen Z, Li G, Wiese D, Zhang B, Smalley WE, Edwards TL, Giovannucci E, Zheng W, Dai Q. Calcium Intake and Ion Transporter Genetic Polymorphisms Interact in Human Colorectal Neoplasia Risk in a 2Phase Study. J Nutr., in press, 2014. PMID: 25165391. 55. Hardaway JA, Wang J, Fleming PA, Fleming KA, Whitaker SM, Nackenoff A, Snarrenberg CL, Hardie SL, Zhang B, Blakely RD. An open-source analytical platform for analysis of C. elegans swimming-induced paralysis. J Neurosci Methods, 232:58-62, 2014. PMID: 24792527; PMCID: PMC4179448. 56. Ye R, Carneiro AM, Han Q, Airey D, Sanders-Bush E, Zhang B, Lu L, Williams RW, Blakely RD. Quantitative Trait Loci Mapping and Gene Network Analysis Implicate Protocadherin-15 as A Determinant of Brain Serotonin Transporter Expression. Genes Brain Behav, 13:261-275, 2014. PMID: 24405699. 57. Ye R, Carneiro AM, Airey D, Sanders-Bush E, Williams RW, Lu L, Wang J, Zhang B, Blakely RD. Evaluation of heritable determinants of blood and brain serotonin homeostasis using recombinant inbred mice. Genes Brain Behav, 13:247-260, 2014. PMID: 24102824. 58. Halvey PJ, Wang X, Wang J, Bhat AA, Dhawan P, Li M, Zhang B, Liebler DC, Slebos RJ. Proteomic analysis reveals unanticipated adaptation of colorectal tumor cells to deficiencies in DNA mismatch repair. Cancer Res. 74:387-397, 2014. PMID: 24247723. 59. Codreanu SG, Ullery JC, Zhu J, Tallman KA, Beavers WN, Porter NA, Marnett LJ, Zhang B, Liebler DC. Alkylation damage by lipid electrophiles targets functional protein systems. Mol Cell Proteomics, 13:849-859, 2014. PMID: 24429493. 60. Tripathi MK, Deane NG, Zhu J, An H, Mima S, Wang X, Padmanabhan S, Shi Z, Prodduturi N, Ciombor KK, Chen X, Washington MK, Zhang B*, Beauchamp RD*. Nuclear factor of activated T-cell activity is associated with metastatic capacity in colon cancer. Cancer Res., 74(23):6947-57, 2014. PMID: 25320007. (* co-corresponding authors). 61. Wang X, Zhang B. Integrating genomic, transcriptomic and interactome data to improve peptide and protein identification in shotgun proteomics. J Proteome Res., 13:2715-2723, 2014. 62. Wang X, Liu Q, Zhang B. Leveraging the complementary nature of RNA-Seq and shotgun proteomics data. Proteomics, 14:2676-2687, 2014. PMID: 25266668. 63. Zhu J, Shi Z, Wang J, Zhang B. Empowering biologists with multi-omics data: colorectal cancer as a paradigm. Bioinformatics, in press, 2014. PMID: 25527095. 5 64. Zhang B, Wang J, Wang X, Zhu J, Liu Q, Shi Z, Chambers MC, Zimmerman LJ, Shaddox KF, Tabb DL Slebos RJC, Liebler D and the NCI CPTAC Network. Proteogenomic characterization of human colon and rectal cancer. Nature, 513:382-387, 2014. PMID: 25043054 6