The Pathological Society Residential Training School For Diagnostic Molecular Pathology Wednesday 23rd – Friday 25th September 2015 Park Plaza Hotel, Nottingham Diagnostic Molecular Pathology is the interrogation of tissue-derived molecules (DNA/RNA/protein) to provide clinically useful information adjunctive to routine histopathological examination. The Pathological Society of Great Britain and Ireland will run a residential training school in Diagnostic Molecular Pathology which will aim to o teach the theory and utility/limitations of commonly used tests; o provide a comprehensive overview of the current use of molecular diagnostics. The course is suitable for Trainee and Consultant Pathologists with little or no experience of diagnostic molecular pathology and for non-clinical scientists (who may have some experience with molecular testing) wishing to learn more about the clinical application of molecular diagnostics. Teaching will be delivered in the form of formal didactic lectures, interactive tutorials and problem-solving exercises Day 1: Tissue Interrogation 08:30 – 08:55 Registration 08:55 – 09:00 Introduction Mohammad Ilyas 09:00 – 09:30 Rubbish In = Rubbish Out: The Importance Of Template Emily Shaw 09:30 – 10:30 The Highs And Lows Of PCR Phillipe Taniere / Brendan O’Sullivan 10:30 – 11:00 Data Interpretation Of Real-Time PCR Phillipe Taniere / Brendan O’Sullivan 11:00 – 11:30 Tea / Coffee 11:30 – 12:30 The Highs And Lows Of Sequencing Rachel Butler 12:30 – 13:00 Data Interpretation Of Sequencing Rachel Butler 13:00 – 14:00 Lunch 14:00 – 15:00 The Highs And Lows Of In-Situ Hybridisation Kate Martin / Adele Calvert 15:00 – 15:30 Data Interpretation Of In-Situ Hybridisation Kate Martin / Adele Calvert 15:30 – 16:00 Tea / coffee 16:00 – 16:30 Chromogenic In-Situ Hybridisation Elizabeth Soilleux 16:30 – 17:00 Design Your Own Assay Mohammad Ilyas 17:30 – 18:30 Industrial Session (each presentation, 20 minutes) Roche: The power of knowing (David Snell) Idylla: A New Generation Molecular Diagnostic System for Sample to Result Testing (Jochen Schuck) Day 2: Tissue Interrogation 09:00 – 10:00 The Highs And Lows Of Microarrays Ian Tomlinson / Christine Blancher/Michal Kovacs 10:00 – 10:30 Data Interpretation Of Microarrays Ian Tomlinson / Christine Blancher/ Michal Kovacs 10:30 – 11:00 Tea / Coffee 11:00 – 12:00 The Highs And Lows Of Next Generation Sequencing Xose Fernandez 12:00 – 13:00 Digital Pathology Manuel Salto-Tellez 13:00 – 14:00 Lunch 14:00 – 15:00 The Liquid Biopsy Brian Walker 14:30 – 15:30 Design Your Own Assay Part2 Mohammad Ilyas 15:30 – 16:00 Tea / Coffee 16:00 – 17:00 Design Your Own Assay Part2 Mohammad Ilyas 17:30 – 18:30 Industrial Session (each presentation, 20 minutes) Thermofisher Scientific : NGS applications in clinical research and diagnostics (Freddie Sharkey) Illumina: Tbc Day 3: Applied Molecular Diagnostics 09:00 – 09:45 Molecular Diagnostics In Gastrointestinal Cancers Newton Wong 09:45 – 10:30 Molecular Diagnostics In Gynaecological Cancers Simon Herrington 10:30 – 11:00 Tea / Coffee 11:00 – 11:45 Molecular Diagnostics In Lymphoid Cancers Ming Du / Richard Byers 11:45 – 12:30 Molecular Diagnostics In Lung Cancers William Wallace 12:30 – 13:30 Lunch 13:30 – 14:15 Molecular Diagnostics In CNS Cancers Tom Jacques 14:15 – 15:00 Molecular Diagnostics In Mesenchymal Cancers Nischalan Pillay 15:00 – 15:30 Tea / coffee 15:30 – 16:15 Molecular Diagnostics In Breast Cancers Emad Rakha 16:15 – 16:45 NEQAS – Ensuring Standards In Molecular Diagnostics Sandi Deans 16:45 – 17:00 Review And Feedback