Nature Communications You are receiving this press release because you have registered to do so at the Nature Publishing Group press site. In registering to receive these press releases, you have agreed to the terms and conditions EMBARGO LONDON NEW YORK Tuesday 19 January 2016 16:00 (GMT) Tuesday 19 January 2016 11:00 (EST) TOKYO SYDNEY Wednesday 20 January 2016 01:00 (JST) Wednesday 20 January 2016 03:00 (AEDT) Wire services’ stories must always carry the embargo time at the head of each item, and may not be sent out more than 24 hours before that time. Solely for the purpose of soliciting informed comment on Nature Publishing Group papers, you may show relevant parts of this document, and the papers to which it refers, to independent specialists – but you must ensure in advance that they understand and accept Nature Publishing Group’s embargo conditions. PRESS RELEASES This press release is copyright Nature Publishing Group. Its use is granted only for journalists and news media receiving it directly from Nature Publishing Group. Full terms and conditions can be found here. The best contacts for stories will always be the authors, but the editor who handled a paper may be available for comment if an author is unobtainable. Please get in touch with Nature Publishing Group's press contacts as listed below with any editorial enquiry. We take great care not to hype the papers mentioned on our press releases. If you ever consider that a story has been hyped, please do not hesitate to contact us at press@nature.com, citing the specific example. NATURE COMMUNICATIONS [2] Genetics: Ancient DNA sheds light on Britain's history of migration *IMAGES* New analyses of the ancient DNA of British individuals help disentangle the impact of migration events from continental Europe into Britain before and after the Anglo-Saxon invasion (circa fifth century AD). The results are described in two separate papers published in Nature Communications. Past genetics studies based on modern genomes have resulted in mixed opinions about the migratory history of people in and out of the British Isles. The recent refinement of techniques that allow the extraction of ancient genetic information can provide insight into the major migration events in human history. In one paper, Daniel Bradley and colleagues sequence the DNA of nine individuals from north Britain, including seven individuals from a Roman era (late BC/early AD) cemetery in York, one from an earlier Iron Age burial and one from a later Anglo-Saxon burial. They find that the whole genomes of Roman-era individuals from northern Britain are similar to the modern British Celtic population and to the earlier Iron Age genomes, but differ significantly from modern day Yorkshire genomes or Anglo-Saxon genomes. The authors show that all Roman-era individuals except one were indigenous Britons in terms of their genomic signal. A single Roman individual possessed high genetic similarity to modern day Middle Eastern and North African populations, suggesting movement of people from very distant areas was taking place within the Roman Empire. In the other paper, Stephan Schiffels and colleagues sequence the genome of ten individuals dating back to the Iron Age and the Anglo-Saxon period, from cemeteries in east England, close to Cambridge. They use present-day genetic data to characterize the relationship of these ancient individuals to contemporary British and other European populations. They show that the contemporary population in eastern England derives approximately 30% of its ancestry from Anglo-Saxon migrations, with a lower percentage in Welsh and Scottish individuals, and find that Anglo-Saxon samples share more genetic similarities with modern Dutch and Danish populations than with Iron Age samples. ARTICLE DETAILS DOI: 10.1038/ncomms10326 Corresponding Author: Daniel Bradley Trinity College Dublin, Dublin, Ireland Email: dbradley@tcd.ie Tel: +353 1 896 1088 DOI: 10.1038/ncomms10408 Corresponding Author: Stephan Schiffels Max Planck Institute for the Science of Human History, Jena, Germany Email: schiffels@shh.mpg.de Tel: +49 151 2350 3215 Please link to the article in online versions of your report (the URL will go live after the embargo ends): http://nature.com/articles/doi:10.1038/ncomms10326 & http://nature.com/articles/doi:10.1038/ncomms10408 Image captions and credits Image 1 Caption: Archaeologists and geneticists work together to explore Anglo-Saxon immigration history in England by analysing ancient Anglo-Saxon skeletons from Cambridgeshire. Photo of an adult female from Oakington complete with early Anglo-Saxon brooches. Credit: Duncan Sayer. Image 2 An Anglo-Saxon woman is carefully excavated from a fifth and sixth century burial ground in Oakington, Caption: DNA from Cambridgeshire archaeological sites were sequenced to reveal Anglo-Saxon immigration history in England. Credit: Duncan Sayer. Image 3 Caption: Excavating a triple grave from Oakington early Anglo-Saxon cemetery. A multidisciplinary team of geneticists and archaeologists work together to explore ancient DNA from sites in Cambridgeshire and reveal Anglo-Saxon immigration history. Credit: Duncan Sayer. Image 4 Caption: This skeleton from a 5th-6th century burial ground in Oakington, East England, was one of 10 samples from which we extracted and sequenced DNA to learn about English population history. Credit: Duncan Sayer. Image 5 Caption: This triple burial from Oakington Cambridgeshire included metal and amber grave goods with continental European characteristics. DNA of ten samples from Oakington and from nearby sites were sequenced to reveal Anglo-Saxon immigration history in England. Credit: Duncan Sayer.