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Health

Allergies

An allergic reaction is an unwanted side effect caused by an inappropriate response of the immune system to various substances such as pollens, mold, dust or insect bites, certain foods, drugs and chemicals. Exposure to them triggers a reaction, usually through itching, sneezing, coughing, tearing, vomiting or diarrhea. The most frequently encountered allergies in Swissys are reaction to certain types of food, flea bites and pollen. Food allergies occurring at a young age sometimes disappear, i.e. the dog outgrows the allergic reaction eventually. Because the cause of an allergy is often difficult and sometimes impossible to determine, allergies can be very frustrating for the owner, and patience is

often the only recourse!

Gastric Dilatation-Volvulus (GDV)

Commonly called bloat and stomach torsion, this is a potentially fatal condition in which a dog's stomach distends with gas, food or fluid and then rotates and twists. The twisting action blocks both the entrance to and the exit from the stomach. Distention and twisting can occur independently of one another. But when both take place, rapid veterinary intervention is absolutely critical. Signs of

GDV may include: - Abdominal swelling and tenderness - Unsuccessful attempts to vomit - Excessive drooling - Restlessness - Panting or labored breathing GDV requires immediate surgery. This entails possible removal of dead stomach tissue, repositioning of the stomach followed by stomach attachment (gastropexy) to prevent the risk of future volvulus. There are several types of stomach tacks. A popular procedure today is the belt-loop gastropexy in which a portion of the stomach is attached to a belt loop flap created in the abdominal wall. Like many other large, deep-chested breeds, Swissys are definitely prone to GDV. While the condition occurs more frequently in dogs over

5 years, it can happen at any age. To date, research on the condition has remained inconclusive, it seems to be multifactor in nature, and i.e. no single food type, ingredient or feeding method has been shown to cause GDV. Indeed, some Swissys have bloated on entirely empty stomachs. Stress may be the triggering factor under certain conditions. And while heredity is suspected by some researchers, no conclusive evidence has been produced to date. At present there are no clear cut preventives for bloat. The most important tool to prevent a fatal ending to GDV is to recognize the signs and get

immediate veterinary care.

Cancer:

Age is the most important risk factor for the development of cancer in dogs, for it is the aging that permits the long-term events leading to tumor development and progression to occur. For most tumor types, the risk for cancer increases with increased age. There are many types of cancer occurring in dogs such as: various types of skin tumors or carcinomas - tumors of the bone such as osteosarcoma - tumors of the lymphoid tissues such as lymphosarcoma - tumors derived from blood vessel such as hemangiosarcoma. To date, Swissys do not appear to be predisposed to a certain form of cancer. And although a few cases of cancer in young dogs have been reported, so far it is clearly the

older population that is subject to the various forms of cancer.

Cataract:

This is the loss of normal transparency of the eye's lens. The opacity is usually white but may also give bluish white cast to the lens behind the pupil. A cataract can be singular or multiple, of any size or shape and may affect the entire lens. The degree of vision impairment is determined by the size and location of the cataract within the lens. While most cataracts are considered to be inherited, some may result from trauma to the eye or from metabolic disorders such as diabetes. Congenital (present at birth) cataracts may or may not be inherited and generally do not progress to blindness. Most hereditary forms of cataract occur in dogs under the age of 5 years. Senile cataracts in older dogs are quite common and are considered to be the result of the aging process. Like any other ocular abnormality, cataracts can be confirmed by an ophthalmologic exam. In general, Swissy breeders will not breed a dog with cataracts unless trauma has been clearly established as the cause of the

condition.

Canine Hip Dysplasia (CHD):

This is the irregular formation of the Cox femoral joint. This is the joint that joins the femur, the longest bone in the body, to the hip socket. The hip is a ball and socket joint, and the ball (femoral head) must fit well into the socket (cup) for the joint to function properly. The main contributors to the development of CHD are joint laxity and the depth of the acetabulum (cup). Early signs of CHD include: - Reluctance to go up and down stairs or to jump - Difficulty rising or laying down - Bunny hopping when running, i.e. both hind limbs move together. Diagnosis is made through radiographic findings, either by the method advocated by the Orthopedic Foundation for Animals (OFA) or by that of the University of Pennsylvania Hip Improvement Program (PennHIP) which measures joint laxity.

While CHD is among the principal orthopedic diseases in the GSMD, fortunately for Swissys, it manifests itself rarely in a severe and crippling form. Indeed, unless x-rays are taken, many Swissy owners are not even aware that they have a dysplastic dog. Quite often, mildly and even moderately affected Swissys do not show any or only very subtle clinical signs of the disease. While treatment options for severely dysplastic dogs are available, we will not discuss them here as they are so rarely applicable to Swissys. Prior to breeding, Swissys should be screened for CHD and evaluated by an

established registry such as OFA or PennHIP. It is preferable to use only CHD free animals.

Elbow Dysplasia (ED):

Manifested as: OCD, FCP(fragmented coronoid process), UAP (ununited anconeal process), DJD

(degenerative joint disease, note that DJD may also occur in the cartilage of other joints). The form most often diagnosed in Swissys appears to be DJD, a slowly progressive form of cartilage degeneration usually caused by trauma or abnormal wear on the joint. DJD is classified as primary

(idiopathic or no known cause) or secondary (a known predisposing cause or injury exists). Anecdotal evidence suggests that most Swissys diagnosed with DJD during radiographs of the elbows for OFA certification fall into the mildest form grade I. They have never displayed any clinical signs such as pain, stiffness, decreased range of motion or lameness. With DJD, genetic predisposition cannot be established as definitely as with other orthopedic conditions. Hence, there is a wide range of opinions among Swissy breeders with regard to breeding a dog affected with DJD grade I. There is, however, general consensus among breeders not to use Swissys with DJD beyond grade I as well as with any of

the other forms of ED.

Entropion (eyelid rolled inward):

Distichiasis (extra eyelashes or row of lashes growing from the lid margins): If present in acute clinical form, both conditions can cause irritation to and possibly damage the cornea. Signs of these defects are excessive tearing, ocular discharge and squinting. Clinical entropion and distichiasis can be very successfully corrected by surgery. While these hereditary conditions are present in Swissys, they are often so minor that they do not present any clinical evidence. This applies in particular to distichiasis. Many Swissys have extra eyelashes which are only apparent upon careful examination of the inside of the eyelids. Like with all ocular abnormalities, Swissys can be screened for these most

frequently occurring defects and registered with the Canine Eye Registration Foundation (CERF).

Ostechondrosis disease (OCD):

Osteochondrosis is a generalized disturbance of the normal development of cartilage. The particular cartilage becomes abnormally thickened and small fissures and cracks may develop. The "disease" refers to the stage when cartilage becomes dissected resulting in cartilage flaps. These flaps may remain attached or become loose and fall into the joint space. In Swissys, the vast majority of OCD cases occur in the shoulder joints and occasionally in other joints such as elbows and hocks. The onset of the disease may begin as early as at 4 months and as late as at 14 months. The most typical age of appearance, however, is between 6 and 8 months. Except for very mild cases without flap development, the clinical signs are almost invariably persistent, and less frequently, intermittent lameness. The dog may be stiff after resting and the lameness is usually aggravated by exercise. OCD is diagnosed by radiography. However, in the early stages, radiographic findings might be inconclusive. In such situations, contrast radiography (arthrography) may be necessary for definite diagnosis. Treatment depends on the severity of the case. OCD lesion in the shoulder joint. Lesion evident on the joint surface of the humeral head Mild cases without cartilage flaps may be treated and heal spontaneously with several weeks of rest and treatment with the drug Adequan and supplements such as Glucosamine and Chondroitin, MSM and Vitamin C. Many cases, however, will require surgery which consists of the removal of flaps and loose fragments and the scraping and smoothening of the defective surface. Surgical repair of OCD of the shoulder usually renders excellent results. Surgical results involving other sites are not as predictable. Because mild forms of OCD can occur without presenting clinical signs, a prudent approach is to radiograph shoulders prior to breeding so that affected Swissys can be eliminated from a breeding program. In fact, Swiss health data has convincingly shown that by excluding affected dogs and bitches, incidences of OCD can be

significantly reduced.

Panosteitis:

Also known as Shifting Leg Lameness or Pano. This is a spontaneous, self-limiting inflammatory disease of the long bones in the legs of young, fast-growing breeds. Most dogs are diagnosed between

5 and 12 months but pano can occur as early as 2 months and as late as 7 years. The vast majority of pano cases are resolved by the age of 2 years. The cause of the disease is unknown but it has been associated with reactions following viral or bacterial infections, von Willebrand's disease and hyperestrogenism in females in association with the first estrus. Clinical signs are persistent or intermittent lameness that may shift from leg to leg, hence the term -shifting leg lameness. Deep palpation of the affected bone will elicit a painful response. X-rays may demonstrate an increased patchy density of the bone cavity with a roughened surface. Diagnosis of pano is very important as acute lameness may signal any of several orthopedic conditions such as OCD or elbow dysplasia.

There is no cure for pano because the disease is self-limiting and hence research on the condition is almost non-existent. Treatment consists of alleviating the pain with analgesic and anti-inflammatory drugs and plenty of rest as restricted activity can prevent more severe pain from developing. Because this disease is self-limiting and causes and heredity are not fully understood, most Swissy breeders do

not consider it as breeding excluding condition.

Patella Luxation:

Also called slipping kneecap or popping knee, this condition is mostly inherited but may in rare cases be caused by trauma. Conditions that predispose to dislocation of the patella are a shallow groove, weak ligaments and malalignement of the tendons and muscles that straighten the joint. The patella slips in- or outward. The signs may include difficulty straightening the knee, pain in the stifle (knee joint) and lameness. The diagnosis is confirmed by manipulating the stifle joint and pushing the kneecap in and out of position. Treatment involves surgery to deepen the groove and/or re-align the tendon. Like with other orthopedic conditions presumed to be hereditary, Swissys with non-traumatic

patella luxation should not be bred

Idiopathic Epilepsy (IE):

This is the term used by most experts to describe the condition of frequent seizures with no identifiable cause. Seizures occur when nerve cells in the brain become hyperexited and send rapidfire messages to the body. If nerve cells in an isolated part of the brain are defective, only part of a dog's body is affected resulting in a partial seizure. Partial seizures are exhibited by localized body movements, such as head bobbing or imaginary fly-biting. If circuits throughout the entire brain misfire, the dog has a generalized seizure. Tonic-clonic seizures involve teeth gnashing, frantic thrashing of the limbs, excessive drooling and loss of bodily functions resulting in uncontrolled urination and defecation. Treatment of IE depends on the severity of the case and may involve daily administration of anticonvulsant drugs such as Phenobarbital, primidone, potassium chloride and others. Unfortunately, all anticonvulsants have some undesired side effects. Some affect liver functions, others can make the dog drowsy or hyperactive or may cause vomiting and constipation. IE is present in all Swissy lines. It typically surfaces between the ages of 1 to 3 years but it can become evident as early as 12 months and as late as 5 years. Unfortunately, no method to identify carriers of epilepsy exists to date. It is only after a dog or a bitch has produced offspring with IE that we can assume that this particular sire or dam is probably a carrier of epilepsy. However, the mode of inheritance of IE is so complex that at the moment no one management method will assure complete control of the disease. Prudent Swissy breeders will not continue to breed a dog or a bitch that has produced 2 or more offspring with IE, and of course no serious breeder will ever consider breeding an affected animal. Many Swissy breeders and owners participate in the all breed DNA research project to locate the genetic marker for IE conducted currently at the University of Missouri/Columbia. We all hope that this research eventually will produce a reliable method to identify carriers of IE and thus help the breeder to better control or even eradicate this heartbreaking, unpredictable and often

lethal disease.

Splenic Torsion:

With this condition, the spleen rotates around its own axis, either away from or towards the stomach. The spleen then becomes engorged with blood and may expand to several times its normal

size. If the spleen rotates away from the stomach it may torsion several times. As many as six revolutions have been observed. If the spleen rotates towards the stomach it may pull it along causing a partial or even complete gastric torsion, creating a very dangerous and potentially fatal situation calling for instant medical attention. Unless the stomach is involved and obvious signs of GDV are present, unfortunately the signs of splenic torsion are often quite vague and may vary from case to case. Signs may include: - Inappetence - Vomiting - Diarrhea or constipation - Low level fever - General listlessness - Tucked up abdomen, tenderness of the abdomen or slight abdominal distention - Pale gums Splenic torsion is a life-threatening condition which requires immediate veterinary care. In a surgical procedure called splenectomy, the spleen is removed. Often, a gastropexy (stomach tack) is performed at the same time if the animal's condition allows this additional procedure. The causes of splenic torsion are not known. Like with GDV, the condition seems to primarily affect large deepchested breeds. In Swissys, dogs over the age of 5 years appear to have a higher incidence; however, quite a few cases of younger Swissys have been reported. For the GSMD, splenic torsion unfortunately is one of the major health problems. Indeed, many breeders believe that probably a significant number of dogs that supposedly died of GDV but were not necropsied after their death actually might have succumbed to splenic torsion. As with GDV, the most important tool to prevent a fatal ending to splenic torsion is to recognize the signs and get immediate veterinary care. Remember, splenic torsion

will kill if not recognized in time to perform life-saving surgery.

“Lickfits”:

This is an entirely unscientific term to describe the sudden onset of frantic licking of anything in range such as carpet, bare floor, walls etc. and the indiscriminate eating of anything that can be swallowed such as grass, leaves, fiber from carpets, toys, clothes, dog blankets, the foam inside those dog beds, zippers etc. and gobbling up of air. It is obvious that the behavior is due to severe gastrointestinal discomfort. It sometimes can be alleviated with medications such as Digel, Gas-X or other gas and acid reducing remedies. Often, hydrogen peroxide to induce vomiting will help. What exactly causes the

"Swissy Lick" is a matter of discussion among Swissy owners but there seems to be no single or definite factor responsible for this condition. Any numbers of theories have been offered, from excessive gas pressure to acid reflux to allergic reaction to a food substance. Some believe that it is a precursor to GDV but this cannot be clearly substantiated either as many Swissys who have had these licking episodes never went on to develop GDV. However, at this time something the dog may eat could cause a blockage. That is why it is best to crate your dog or have them in a puppy proof/safe place when you are not with them. While the condition appears to affect primarily young dogs, it has

also been reported in older Swissys. Often, young dogs eventually will outgrow the condition.

Preliminary Evaluations for animals under 24 months

OFA policy on Releasing Preliminary Evaluations to the Public Domain.Frequently, breeders want early knowledge of the hip status on puppies in a given litter. Preliminary hip evaluations may be as valuable to the owner or breeder as the final OFA evaluation. This allows early selection of dogs for use as show/performance/breeding prospects and dogs best suited for pet homes. The OFA accepts preliminary consultation radiographs on puppies as young as 4 months of age for evaluation of hip conformation. If the dog is found to be dysplastic at an early age, the economic loss from the cost of training, handling, showing and so forth can be minimized and the emotional loss reduced. These preliminary radiographs are read by the OFA veterinary radiologists and are not sent to outside

radiologists. The same hip grades are given to preliminary cases.A recent publication* compared the reliability of the preliminary evaluation hip grade phenotype with the 2 year old evaluation in dogs and there was 100% reliability for a preliminary grade of excellent being normal at 2 years of age

(excellent, good, or fair). There was 97.9% reliability for a preliminary grade of good being normal at 2 years of age, and 76.9% reliability for a preliminary grade of fair being normal at 2 years of age.

Reliability of preliminary evaluations increased as age at the time of preliminary evaluation increased, regardless of whether dogs received a preliminary evaluation of normal hip conformation or HD. For normal hip conformations, the reliability was 89.6% at 3-6 months, 93.8% at 7-12 months, and 95.2% at 13-18 months. These results suggest that preliminary evaluations of hip joint status in dogs are generally reliable. However, dogs that receive a preliminary evaluation of fair or mild hip joint conformation should be reevaluated at an older age (24 months).*Corley, EA, et al. Reliability of Early

Radiographic Evaluation for Canine Hip Dysplasia Obtained from the Standard Ventrodorsal

Radiographic Projection. JAVMA. Vol 211, No. 1

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