Now we are searching for these candidates in Pharmaceutical/Biotech Industry, Any applications, Please contact: xing_shaoguo@wuxiapptec.com;global_talent@wuxiapptec.com Campus Recruiting Position 1. Cell Immunology Senior Scientist 2. Analytical/Bio-analysis R&D Position (Senior Scientist or above) 3. Formulation/Pre-Formulation position (Sr. Scientist or Leader) 4. Bioinformatics, Senior Scientist and above 5. In vivo pharmacology scientific leader 6. Computational Chemists 7. Chemistry Senior Scientist and above 8. Senior/Principal Scientist of Process Research Development 9. Sr. Scientist/Assistant Director-GPCR 10. Sr. Scientist Bioassay and Biological Characterization 11. Sr. Scientist of Biology 12. Study Director of DMPK 13. Sr. Scientist of DMPK in Life 14. Biologics Senior Scientist- Protein Formulation Development 15. Biologics Senior Scientist- Cell Culture Process Development 16. Sr. Scientist of Downstream Process Development 17. Biologics Senior Scientist- Protein Analytical Sciences 18. ADME Sr. Scientist or above 19. Sr Scientist of Antibody-drug conjugate 20. QC-Analytical Science and Technology Sr. Scientist Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website Campus Recruiting Position 1.Cell Immunology Senior Scientist Responsibilities: The Scientist – Immunology brings technical expertise to a new initiative program at WuXi AppTec. He/she is an essential part of the team responsible for this cell therapy project. This individual leverages his/her existing technical expertise to further the goals of the project. His/her primary responsibility is to perform Cell Therapy Research group’s immune cell culture/manipulation, immunology assay development /execution and other related works. This individual should have a proven track record of immunology techniques and expertise. The Scientist – Immunology works closely with other team members and technical staff to carry out project goals and objectives. Carry out immune cell and immunology related work. Coordinate and manage tasks as assigned, and identify new areas where action is required. Direct and assist with experimental and equipment troubleshooting efforts. Assist and train other members, as necessary. Document work and prepare written and oral reports and/or publications with accuracy and reliability Demonstrate integrity, credibility and a positive attitude in daily performance so as to motivate others to do the same Basic Qualifications: To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. PHD / Master in a immunology with 1-3 years relevant work experience Experience on immunology laboratory maintenance is preferred Extensive immunology knowledge, experience and technical skills. Experience in microscopy. Experience on FLOW cytometry will be a plus. Experience and knowledge in molecular biology. Experience on gene delivery will be a plus. Experience working in a cross disciplinary environment in academia or industry is preferred. Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 2.Analytical/Bio-analysis R&D Position (Senior Scientist or above) Responsibilities: Lead efforts for analytical development, stability studies within ASC department; function as project leader role in analytical & stability projects for biologic drug products Plan and execute batch release, stability study for biologics of drug substances/drug products; perform stability and release analyses, but not limited to samples for drug substances /drug products used for clinical trials Author, review and/or approve the analytical methods, method validation reports, stability study reports, Certificate of Analysis (CoA), summaries/reports, etc. Basic Qualifications: Analytical R&D Ph.D. or Master Degree in analytical chemistry, pharmaceutical analysis or other directly-related science discipline with experience or training in analytical chemistry, pharmaceutical analysis or equivalent experience. Must have overseas study or working experience and industrial experience in Analytical R&D field. Must be familiar with the requirements of the FDA cGMP/GLP regulations, ICH guidelines and industry trend/practice in analytical development requirements. Must be able to coach junior scientists or managers to accomplish performance objectives. Experience with late phase programs is desired. Small Molecular Bio-analytical R&D BS, MS, PhD degree in a science discipline with experience or training in analytical chemistry, or equivalent experience. Execute and follow the policies and SOPs of BAS department and company. All work will be conducted in compliance with FDA Good Laboratory Practice regulation and OECD GLP guidelines. Expected to be a supervisor and train junior employees. Open exchange of information and project teamwork will be required in order to meet performance. There must be strong recognition of high performance standards and of meeting assignment target dates at the individual job level as well as for the benefit of coworkers on project teams. Training in or experience with the requirements of FDA GLP regulation and OECD GLP guidelines is required Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website Must be experienced with standard analytical techniques, particularly HPLC and LC-MS. Large Molecular Bio-analytical R&D PhD with several year’s experience in relevant industrial experience. Solid knowledge and skills in Immunology, Biochemistry, Biology, Immunoassays, ELISA, ECL, MSD. Hands-on experience on immunoassay development, validation, and sample analysis. Skilled executive with extensive experience in leading small and large molecules bioanalysis laboratories is a must for Ex. Director level and above Proven ability to motivate, mentor and work efficiently, as well as with persons from other cultures, both in cross-functional and self-directed work teams Good communication skills in both English and Mandarin Chinese Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 3.Formulation/Pre-Formulation Position(Sr. Scientist or Leader) Description WuXi’s development services also include pre-formulation studies, analytical development, stability evaluation and formulation development, all the way to CMC services. All of these services are integrated to help our clients quickly and seamlessly move NCEs from preclinical stage to patients. Our development services include: Pre-Formulation Development Analytical Development Formulation Development Clinical Trial Material Manufacturing, Packaging & Labeling Basic Qualifications: M.S. or Ph.D. degree in pharmaceutical science, pharmaceutical analysis, analytical/physical chemistry, pharmaceutics or other directly-related science disciplines. Experience in formulation/dose development and pre-formulation development is helpful but not required. Familiarity with analytical techniques, especially HPLC; Experience with solid-state characterization, analytical techniques is desirable. Familiarity with the requirements of the FDA cGMP/GLP regulations, ICH guidelines as well as drug development process. Strong communication skills, both written and verbal, and outstanding interpersonal skills are essential job requirements. Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 4.Bioinformatics, Senior Scientist and above, Responsibilities: Perform data analysis on next generation sequencing (NGS) and microarray data. Interact with our clients and provide bioinformatics support. Evaluate and implement open source/third party bioinformatics solutions. Develop scripts (perl or python) for NGS analysis pipeline. Basic Qualifications: Ph.D. in bioinformatics, computational biology, statistics or related fields with a minimum of 3 year hands-on experience in sequencing bioinformatics Working knowledge in drug development and pharmaceutical industry is strongly preferred. Experienced in WGS, RNASeq analysis; understanding CNV and genetic analysis. Familiar with molecular biology and molecule pathway. In-depth knowledge of existing NGS data analysis technology, tools and databases, familiar with statistics and genetics analysis. Proficient in perl/python and R. Previous project and operation management and experience is highly preferred Excellent written and verbal communication skills in both English and Mandarin Chinese. Strong organizational and teamwork skills. Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 5.In vivo pharmacology scientific leader Function: CNS and Metabolic Disease Research Area Responsibilities: The position is a key scientific leadership role in the metabolic disease unit with accountability for the success of client projects. Expected to lead multiple scientific projects for achieving delivery of setting up, validating and executing metabolic disease assays. Join integrated project as in vivo pharmacology contact, to be able to communicate with clients both orally and via emails; Based on client needs, identify and propose in vivo strategy and study plan Responsible for key new capability and technological development Lead a group by providing scientific input, monitoring project process, and QC data and results Able to coordinate internally Able to provide scientific proposal to extend current projects Understanding of latest developments in relevant scientific field; Lead study directors to execute the studies and summarize the results. Report to the clients and interpret data. Expert in metabolic disease fields (including, but not limiting to Nonalcoholic fatty liver disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH) animal models as well as diabetes etc.); Ability to solve problems and troubleshoot. Basic Qualifications: Ph.D in pharmacology or metabolic disease; > 2 years working experience in the related research fields Candidates with industry (drug discovery) experience are preferred CRO experience is a plus Excellent written and verbal communication skills in both English and Mandarin Chinese. Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 6.Computational Chemists Responsibilities: As a computational chemist, you will be responsible for the application of computational chemistry methods to identify, optimize and develop drug candidates. In addition, you will interact closely with Medicinal Chemists and Biologists, applying CADD methods to the hit-to-lead and lead optimization projects, presenting the modeling results to the client and communicating with the client on the design idea and strategies. You will also be proactively involved in projects by exhibiting excellent communication and problem-solving skills to demonstrate value-added support to the client’s projects. Basic Qualifications: The qualified candidate will have a PhD in Computational Chemistry or related field, Postdoctoral and 2 to 5 years industrial experience preferred. In addition, you should have: Expertise in structure-based design and ligand-based design, molecular docking, virtual screening, homology modeling, pharmacophore elucidation and QSAR. Be familiar with broad target classes such as enzymes (i.e. kinases, proteases and esterases), GPCR, ion channels, and protein-protein interactions. Extensive experience with commercial modeling software. A strong record of accomplishment (papers, patents and presentations). A strong team work ethic and excellent communication and presentation skills. Excellent written and verbal communication skills in both English and Mandarin Chinese. Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 7.Chemistry Senior Scientist and above Responsibilities: Define chemistry project team objectives, timelines, and work plans Design compounds based on SAR, and have them synthesized and evaluated Identify and solve synthetic and medicinal chemistry problems to advance the project Communicate effectively in both verbal and written form and participate in regular discussions with the team, the client and supervisor in regards to status of projects, potential issues and plans Interact closely with biology, DMPK scientists both within WuXi and with our partners Basic Qualifications: Ph.D. in organic chemistry 2-3 years of Pharm industrial experience degree is a plus Thorough knowledge of synthetic organic/medicinal chemistry, demonstrated expertise in organic synthesis, chromatographic purification methods, and compound characterization using modern analytical techniques (NMR, MS, HPLC, etc.) Proven track record of scientific achievement through publications and patents Demonstrated leadership with teamwork spirit Show a strong sense of responsibility and work ethic Able to make reasonable judgment under a pressure and in a complex circumstance Excellent written and verbal communication skills in both English and Mandarin Chinese. Job Function: Research & Development Primary Location: China Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 8.Senior/Principal Scientist of Process Research Development Responsibilities: Excellent knowledge of organic chemistry and organic synthesis, extensive experience in literature search and route selection, and familiar with spectra interpretation and compound identification. Able to independently design new route routes and explore the alternative synthesis. Capable of handling multiple complex projects at the same time, preparing the project plans, executing the plans and solving potential problems. Familiar with plant equipment and operations, providing production support and conducting trouble-shooting in the plant to ensure the success of the manufacturing. Complete weekly dates, final reports and campaign reports in a timely manner. Teleconference with the clients. Able to discuss the technical issues with the clients and answer the clients’ questions. Lead a small team with a few chemists. Coach and train junior chemists. Implement and comply with company and department policies such as EHS and IP policy Basic Qualifications: Master’s degree or above in organic chemistry, medicinal chemistry, chemical engineering, or related fields. Extensive knowledge and hands-on experience in organic chemistry, process R&D and GMP regulations. . Excellent written and verbal communication skills in both English and Mandarin Chinese. Skilled on Microsoft Word, Excel and PPT, chemdraw software etc. As a master, 7 years or above experience in organic synthesis or process R&D and 4 years or above research projects management. As a doctor, 3 years or above experience in organic synthesis or process R&D and 2 years or above research projects management. Excellent skills in problem solving, communications, project management and coordination, and team building. Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 9.Senior. Scientist/Assistant Director-GPCR Responsibilities: Experienced individuals to manage in vitro/ex vivo GPCR assays; training junior scientists to support medicinal chemistry programs; leading and managing projects Develop, validate and perform various in vitro and ex vivo assays Conduct primary screening, secondary/functional assays, and/or mechanism of action studies to support drug discovery programs Led a project team in study design and trouble shooting technical problems Responsible for interpreting and communicating data as well as preparing study reports Basic Qualifications: Ph.D in Biological Sciences with extensive laboratory experience in receptor assay development Independently manage multiple projects Work in a team-oriented, multi-disciplinary environment. Excellent written and verbal communication skills in both English and Mandarin Chinese. Industrial experience preferred, but not absolutely necessary Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 10.Sr. Scientist Bioassay and Biological Characterization Responsibilities: Lead bioassay development activities. Accountable for bioassay applications for early and late stage development programs, bioassay qualification/validation, troubleshooting, direct supervision of scientific staff, and strong collaboration with partner organizations. Develop talent, inspire innovation and operational excellence and foster a continuous learning environment. Draft and review regulatory submissions including INDs and BLAs. The applicant should be an effective communicator of ideas, project goals and results to cross-functional team members. Candidates should be self-motivated and organized, familiar with the relevant literature. The applicant will make decisions affecting direction of project and for ensuring project timelines are met. Strong knowledge of GMPs. Regulatory audit and inspection experience preferred. Hands-on technical leadership of all aspects of potency assay development. Direct scientists in the initiation and execution of laboratory experimentation, considering economic, regulatory and safety factors. Basic Qualifications: Requires a Ph.D. in Cell Biology, Molecular Biology, or Immunology and 510+ years of relevant experience that demonstrates an expertise in potency assay development and scientific accomplishments. Industry expert in the development and validation of biological assays for CMC applications. Record of scientific technical writing skills as demonstrated by peerreviewed publications in science and technology journals. Excellent written and verbal communication skills in both English and Mandarin Chinese. Experience interacting with health authorities (FDA, EMA etc.) is required. Managerial experience by providing on-going mentoring, supervision, and yearly performance review and appraisal of a large group of scientists. Extensive hands-on experience in potency assay development (reporter gene assays, proliferation assays, antibody effector function assays, other fluorescence and luminescence based assays, etc.). Experience with immunoassay and nucleic acid assay development is a plus. Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 11.Senior. Scientist of Biology Responsibilities: We are looking for an energetic and enthusiastic Ph. D level scientist to join our dynamic team, based in Shanghai China, to work on in vitro drug discovery programs focusing on biological assay validation and gene function studies. The candidate is expected to lead various client projects and internal assay development efforts. Basic Qualifications: The ideal candidate should possess strong leadership with project management and communication skills including English proficiency, with preferable expertise in cell biology, molecular biology or biochemistry. We are especially interested in candidates with solid experiences in various gene knockdown/ knockout (such as ShRNA, CRISPR construction and characterization, SiRNA screening etc.) and overexpression techniques and functional characterization of genes of interest. Background in signal transduction and cancer biology is a plus. Excellent written and verbal communication skills in both English and Mandarin Chinese. Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 12.Study Director of DMPK Responsibilities: Capable of representing the entire DMPK function to support drug discovery and/or development programs. Clearly understand the scope and milestones of the programs. Identify DMPK challenges and propose roadmap and solutions as appropriate. Communicate proactively with clients and propose/agree on DMPK studies to address key program issues or potential risks. Collaborate with functional groups to conduct study design and submit study requests timely. Work closely with internal functional groups to monitor the progress of submitted studies and ensure timely execution. Propose alternative plans when an accident or unexpected event occurs. Analyze and integrate all data (in vitro ADME, in vivo PK, BA and met ID) to assess if conducted studies have addressed or clarified the scientific questions asked, or have tested the hypothesis proposed earlier. Ensure timely delivery of study reports to the clients with high quality and an appropriate scientific summary. Formulate hypotheses and scientific rationale to account for the study results and propose further studies to confirm it as appropriate. Be able to consolidate DMPK data and present in DMPK program review. Invite advices and advocate scientific discussions as needed. Work with all functional groups to offer technical support to the study design, quotation, and conduct; move studies forward with sense of urgency: thinking on behalf of client. Put high value on technical input from technical staff that perform the actual study. Exhibit superior verbal and written communication skills and exhibit superior interpersonal and leadership skills as necessary to ensure study activities conducted by multiple groups are executed smoothly and according to the protocol. Effectively manage multiple studies and review and deliver final report in a timely manner to serve the client. Be able to work independently on assigned studies under minimal supervision. Provide support for both drug discovery and development DMPKs; lead or coordinate cross BU integrated programs. Basic Qualifications: Ph.D. or equivalent degree with 5-10 years' industry experience in the field of drug metabolism and pharmacokinetics or equivalent life-science based discipline. Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website In depth knowledge of DMPK with extensive hands-on experience on common ADME assays, PK analysis, simulation and modeling. Capable to identify and solve DMPK issues under minimum guidance. Familiar with early discovery strategies and/or late stage development process. Experience with Medchem programs and FDA/CFDA IND filing is a plus. Able to work independently and communicate effectively with a multidisciplinary team of medicinal chemists, biologists, pharmacologists and toxicologists. Excellent written and verbal communication skills in both English and Mandarin Chinese. Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 13.Sr. Scientist of DMPK in Life Responsibilities: Responsible for every procedure of studies including but not limited to: protocol reading, key procedure monitor and implement, and communicate with team member/GL/SD effectively to solve any urgent study issues; Assist in scheduling and task assignment; Responsible for establishing standard procedures, implement accordingly, and provide relevant feedback; Responsible for identifying and solving problems and potential problems about studies, taking part in discussing relevant solutions and implementing the final decision; Provide scientific knowledge training to the group; Set himself/herself as an example and arrange group members to learn and practice company compliance standards. Basic Qualifications: Be equipped with Master's degree or above, have more than 3 years working experience in laboratory animal area; Possess animal science, veterinary medicine, biology and PK related major as professional background; Keen to learn new things, and have a strong will in finding new ways to improve work efficiency and quality; Have a strong sense of responsibility, and a strong communication ability Excellent written and verbal communication skills in both English and Mandarin Chinese. Be skilled at document retrieval (CET-6 certificated). Having published paper in English science journal is preferred (First author is plus). Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 14.Biologics Senior Scientist- Protein Formulation Development Responsibilities: Responsible to contribute and then lead the development of formulation for monoclonal antibodies, recombinant proteins, fusion proteins, antibody-conjugated drugs, and other biologics. Contributor in a formulation team and then lead the team in Shanghai, China to support formulation development, stressed studies, container closure system selection and process development for protein drugs or other parenteral drugs. Contribute to and then lead pre-formulation studies to characterize candidate molecule and elucidate degradation pathways to gain understanding of stability challenges and develop strategies for stabilization. Collaborate with analytical, cell culture and purification and fill/finish teams to lead the development and transfer of biosimiliars, new formulations, container closure systems and fill-finish technology to support toxicology study, clinical development, tech transfer, and process validation for internal or external partners. Collaborate with vendors, draft and then execute qualification of formulation and fill/finish instruments and equipments. Plan, assign, direct and evaluate the work of technical staff when assigned to the project to meet aggressive project timelines. Supervise lower level scientists and evaluate their performance. Present results internally and externally at weekly and monthly meetings with customers as well as industrial and scientific conferences. Basic Qualifications: Excellent written and verbal communication skills in both English and Mandarin Chinese. Hands-on some analytical instruments and methods such as DSC for liquid,DLS, CD,FTIR, SEC,IEX,SDS-PAGE,IEF,CE, UV spectroscopy, Karl Fischer coulometer, cIEF, Osmometer, particle counter and be able to interpret analytical data Hands-on and in-depth understanding of different protein chemistry characterization and stabilization techniques, as well as pharmaceutics relevant to drug product development including lyophilized, liquid and suspension dosage forms. Good understanding of GMP, pharmacopea testing and regulatory requirements for filing and registration of biologics with some knowledge of Quality by Design approach. Ph.D. degree preferably in pharmaceutical chemistry, biochemistry, biophysics, biology or engineering discipline Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website The qualified candidate must be able to effectively partner with diverse team members from various functions at various levels in organizations. Must be a self-starter, be able to work with minimal supervision in a matrix environment and effectively manage multiple projects. Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 15.Biologics Senior Scientist- Cell Culture Process Development Responsibilities: The Scientist will lead a team of staff members in the development of stable cell lines for recombinant proteins for clients around the world. This scientist will be responsible for upstream cell line development and clone selection. The successful candidate will develop strategies and oversee project execution at Wuxi AppTec. Able to applies expertise to cell line development projects to produce stable cell lines suitable for clients’ human clinical trials with experience of transfection, selection and amplification protocols Design experimental plans, lead cell line development execution. Critically analyze cell culture data, interpret and integrate experiment results. Responsibilities include regular communications with external clients to update project status, writing interim and final technical reports. Maintain records sufficient to support regulatory filings Investigate, create and develop new methods and technologies for advancements in the area of cell line development Basic Qualifications: Hands-on experience in mammalian cell culture or microbial fermentation using bioreactors is preferred Experience with recombinant protein expression is a plus. Have strong expertise in process optimization, scale-up and technology transfer. Experience with medium optimization, DoE studies, regulatory submission to the FDA/EMEA and personnel management is preferred. Key aspects of the position include coaching, mentoring and managing junior staff members, Technical oversight of study design, execution and results interpretation. Ability to accomplish the described duties through the use of appropriate computer equipment and software (i.e. Microsoft Word, Excel and Outlook). Must be able to write effectively as demonstrated through authorship of technical reports, and SOPs. Good record of publication and strong communication skills. Must be able to follow detailed instructions and record information clearly and accurately. We are seeking a candidate with PhD degree and 0-2 years industry or postdoc experience. Have background in one of the following fields: biochemical or biological engineering, cell/molecular biology, biochemistry, or microbiology. Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website Industrial experience in the Biotech/Biopharma environment is a strong plus. Excellent written and verbal communication skills in both English and Mandarin Chinese. Ability to take on multiple tasks simultaneously. Must be able to wear appropriate Personal Protective Equipment (PPE). Must be able to effectively communicate detailed information through verbal and written communication and demonstrates effective interpersonal skills. Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 16.Sr. Scientist of Downstream Process Development Downstream Process Development Shanghai subdivision is responsible for the purification process development, scale-up, technical transfer and support for the pre-clinical and clinical manufacturing at Wuxi AppTec biological facility in Wuxi, China. The scope of downstream process development includes the cell culture clarification (centrifuge and depth filtration), column chromatography, viral inactivation/removal, and ultrafiltration/diafiltration. Responsibilities: Leads 2 – 3 scientists to develop scalable protein purification processes for pre-clinical and cGMP clinical manufacturing, Troubleshoot the issues of manufacturing, and develop new purification technology to improve the development efficiency and low the cost of development. Design the downstream processes that are efficient, robust and scalable for the clinical manufacturing. Assist the group leader to coordinate the work between the downstream development group and other functional groups to meet the project objectives and timelines. Coach the junior staff on the process development and validation. Establish the robust purification development and scale-up platform. Basic Qualifications: PhD with 1+ years downstream process development experience Experience in developing the large-scale chromatography, centrifuge and depth filtration harvest, ultrafiltration/diafiltration, and viral inactivation and removal At least one year’s leading project experience Experience in technical transfer. Ph.D from Biochemistry, Biophysics, or related fields. Proven track record of productivity and publications. Excellent written and verbal communication skills in both English and Mandarin Chinese. Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 17.Biologics Senior Scientist- Protein Analytical Sciences Responsibilities: Manages a group of 5-7 scientists in a fast paced environment. Manage time lines and deliverables and communicate with customers. Scientific leader in membrane protein chemistry and/or insect cell expression. Basic Qualifications: Ph.D with 0-2 industry experience OR MS degree and at least 3 years industry experience Industrial Experience in the area of analytical development for protein therapeutics is preferred. Extensive experience in membrane protein chemistry, preferably in GPCR and/or insect cell expression. Excellent written and verbal communication skills in both English and Mandarin Chinese. Ability to take on multiple tasks simultaneously. Ph.D from Biochemistry, Biophysics, or related fields. X-ray structure determination of GPCRs. Proven track record of productivity and publications. have background and hands on experience in one of the following fields: HPLC (SEC, RPLC, CEX), CE (CE-SDS, iCIEF), Mass Spectrometry (QTOFMS,Orbitrap MS), ELISA assays, Cell-based assays, processrelated impurity assays (residual DNA, residual protein-A, HCP, etc.). Seek a motivated, driven, goal oriented, ambitious talent Have business sense in addition to scientific leadership. Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 18.ADME Sr. Scientist or above Responsibilities: Perform ADME (metabolism in different matrixes, CYP inhibition or induction, protein and/or tissue binding, or permeability and transporter assays) studies according to protocol Generate, review, and interpret the data Write study reports in both English and Chinese Maintain instruments Work cooperatively with other groups within the department Basic Qualifications: Bachelor degree with a minimal 2 years of industry experience and demonstrated accomplishment; master degree with relevant experience in ADME Hands-on experience and extensive knowledge of ADME Excellent written and oral communication skills Able to conduct literature research including in English Proficient in the use of Microsoft Word, Excel, and Powerpoint Experience with lab automation is a plus Bachelor or master degree in pharmaceutical sciences, enzymology, cell and molecular biology Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 19.Sr Scientist of Antibody-drug conjugate Responsibilities: Antibody-drug conjugate (ADC) group of WuxiBiologics, WuxiApptec, is recruiting a senior scientist with strong chemistry/biochemistry background to lead customer-service projects of ADC research and development. Major work of the scientist involves protein-drug conjugation, purification and characterization of the conjugate. Basic Qualifications: The candidate should hold PhD degree in chemistry or biochemistry or equivalent, worked in organic chemistry or biochemistry with analytical and purification experience. The incumbent will work in a vibrant research group so dedication and team play is a must. Excellent communication skill is required because of customer relationship. Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website 20.QC/Analytical Science and Technology Sr.Scientist Responsibilities: Perform analytical method development/optimization, qualification/validation Generate and review technical documents such as methods, qualification/validation protocols and reports. Serve as technical lead to solve technical challenges and support laboratory investigations. Perform QC release/stability testing as necessary. Basic Qualifications: Graduate degree in analytical chemistry, biochemistry, molecular/cell biology or related fields. Candidates with BS degree must have minimum 2 year of relevant industry experience. Knowledge and expertise in at least one of the following areas: Biochemical assays such as ELISA, cell based assay, qPCR, Western blot, enzyme activity testing Separation assays such as HPLC, CE, gel electrophoresis Biophysical assays such as MS, spectroscopy (UV, FTIR, CD, fluorescence, etc.), DSC. Strong communication skills in English and Chinese, fluent in speaking, writing and reading in both languages. Critical thinking, scientific reasoning and problem solving skills. Job Function: Research & Development Primary Location: China – Shanghai Contact Info: Email:global_talent@wuxiapptec.com You can check all from“CareerBuilder”“51job”and WuXi AppTec Official website