Chapter 3 FE EXAM FORMATTED PROBLEMS 3-1. A four year old child has been playing in soil contaminated with 500 mg/kg of tetrachloroethylene. It is estimated that he ingested 5g/d of soil over a single 3 month period. The exposure frequency was 7 days per week. What is the estimated chronic daily intake of tetrachloroethylene for the child over the 3 month period? From Eq. 3-14 (CS )( IR)(CF )( FI )( EF )( ED) ( BW )( AT ) From Table : BW 16 kg CDI EF (7day / week)(3months / year)(4weeks/ month) 84 days/ year CDI 3-2. (500 mg / kg)(5 g / day)(1000 mg / g )(10 6 kg / mg )(1.0)(84 day / year) 0.156 mg / kg d (16 kg)(84 days) Characterize the risk of an oral chronic daily intake of 50 ppb of arsenic. From Table 3 - 3 Arsenic 1.5 kg d mg Risk 0.050 mg kg d 1.5 kg d mg 0.075 Because 0.01 use Eq. 3 - 19 Risk 1 exp 0.075 1 0.928 0.072 3-3. Characterize the hazard of an oral chronic daily intake of 0.005mg/L of cadmium. Using Table 3 - 4 and Eq. 3 - 20 0.005 mg/L HI 10 0.0005 mg / L 3-4. Estimate the concentration of Heptachlor in fish if the concentration in water is 5 ppb. The bioconcentration factor is 15,700. 1ppb 1g/L 5ppb 5g/L or 5 10 -3 mg/L From Eq. 3 - 9 Concentration in fish 5 10 3 mg / L 15700 L / k g 78.5mg / k g