Pollution and Human Health Environmental Effects ∆ Pollution causes illnesses in two main ways. First, pollution may cause illnesses directly by poisoning. Second, pollution may cause illnesses indirectly by infectious disease that are spread in polluted environments. ∆ The World Health Organization (WHO) has begun to collect data on how the environment affects human health. They found that people in developed countries suffer less from environmental causes of poor health. In developing countries, environmental causes of poor health are largely due to parasites and bacteria in polluted water and insect-borne diseases. Toxicology ∆ Almost any chemical can be harmful if large enough amounts are taken in. ∆ To determine the effect of a pollutant on health, we to know how much of the pollutant is in the environment and how much gets into the body. We also need to determine what concentration of the toxin damages the body. ∆ The damage to health that results from exposure to a given dose is called the response. This also depends on the number of times a person is exposed, the person’s size, and how well the person’s body breaks down the chemical. ∆ Persistant chemicals are dangerous because more people are likely to come in contact with them and they are more likely to remain in the body. ∆ Exposure to any amount of the chemical less than the threshold dose has no adverse effect on health. Exposure to levels above the threshold dose usually leads to more or increased adverse effects. Epidemiology ∆ Epidemiologists collect data from health workers on when and where cases of a disease have occurred. Scientists then trace the disease to try to find its origin and how to prevent it from spreading. ∆ In order to safeguard the public, health officials determine the risk posed by particular pollutants. The risk is the probability of a negative outcome. ∆ In the case of human health, risk is the probability of suffering a disease, injury or death. ∆ During the process of risk assessment, scientists first compile and evaluate existing information on the substance. Then they determine how people might be exposed to it. The third step is determining the toxicity of the substance. Lastly, scientists characterize the risk that the substances pose to the public. ∆ The Environmental Protection Agency (EPA) formulates the regulations that are sometimes handed down by the government of how and where substances can be used. Pollution from Natural Sources ∆ Naturally occurring pollutants usually become hazardous to health when they are concentrated above their normal levels in the environment. ∆ The most common pollutants from natural sources are dust, soot and other particulates. ∆ Dangerous heavy metals include the elements arsenic, cadmium, lead, and mercury. These metals occur naturally in rocks and soil. Most of them cause nerve damage when they are ingested beyond their threshold dose. Pollution from Human Activities ∆ Only about 10% of commercial chemicals have been tested for their toxicity and about 1,000 new chemicals are introduced every year. ∆ Things have improved, people living in the U.S. contain lower levels of some toxic chemicals in their bodies, on average, than they did in the recent past. ∆ In 2001, 2003, 2005 the Center for Disease Control and Prevention (CDC) released studies on chemical residues in the U.S. population. The levels of nicotine, mercury, and other toxic chemicals were lower than what they had been in 1991. ∆ Despite advances in public health resulting from pollution control, air pollution is still a major health problem. Major pollutants found in the air include gases, carbon monoxide and particulates. ∆ Pesticides are beneficial in that they allow us to grow more food by reducing pest damage. A downside is that because they are designed to kill organisms, they are often dangerous to humans in large doses. ∆ Most modern pesticides break down quickly in the environment into harmless substances. ∆ We are exposed to low levels of industrial chemicals every day, particularly inside new buildings that have new furnishings. ∆ Often industrial chemicals are not known to be toxic until they have been used for many years. ∆ Much of the pollution in our environment is a byproduct of inadequate waste disposal. Examples of this include: 1. wastewater from cities 2. old landfills 3. sewage treatment plants 4. radioactive waste Biological Hazards ∆ One of the reasons these diseases are now widespread is that we have altered our environment in ways that encourage them to spread. The Environment’s Role in Disease ∆ Infectious diseases are caused by pathogens. Some diseases are spread from person to person through air. Other diseases are spread by drinking water that contains the pathogen. Still other diseases are transmitted by a secondary host. Waterborne Disease ∆ Nearly three-fourths of infectious diseases are transmitted through water. In developing countries, where there is not enough water for basic needs, the local water supply is often used for drinking, washing and sewage disposal. ∆ The deadliest waterborne diseases come from drinking water polluted by human feces. These pathogens cause diseases such as cholera and dysentery. ∆ Malaria, another waterborne disease, was once the world’s leading cause of death. No effective vaccine for malaria exists, but preventative measures are used to control mosquitoes. Environmental Change and Disease ∆ Many ways in which we alter the environment make the environment more suitable for pathogens to live and reproduce. ∆ Our actions cause pathogens to evolve resistance to antibiotics that are used to kill them. ∆ We also use enormous amounts of antibiotics to treat human illnesses. ∆ The mosquitoes that transmit malaria are found in the warmer parts of the world. Epidemiologists believe that global warming may increase the areas that malaria occurs ∆ Mosquitoes have evolved resistance to most of the pesticides. Newer methods for controlling mosquitoes involve spreading growth regulators that prevent mosquito larvae from maturing into adults or that sterilize the female mosquitoes. ∆ Most viral diseases spread directly from one person to another. The virus invades the body through a cut or through mucus membranes. ∆ We don’t have many effective drugs to treat viral diseases, and the drugs we have are effect against specific viruses. Our main defense against viral disease is vaccination. ∆ The problem with vaccines is that they are very specific and viruses evolve rapidly. When a new strain of viral pathogen evolves, a new vaccine must be developed. ∆ In recent years, scientists have discovered an increasing number of pathogens that have moved from one species to another. ∆ The pathogens that cause these diseases have lived for centuries in some species of wild animals and done little damage. When the pathogens invade humans, the pathogens cause serious diseases. ∆ Some ecologists think that the ways in which we are altering the environment and destroying habitats ensure that diseases like these will become more common in the future. ∆ Because flu is so easily spread from one person to another, epidemiologists predict that the greatest threat to human health may be the outbreak of a new, very virulent strain of influenza virus, which would spread rapidly through crowded urban populations.