Analytical Chemistry
CHEM 2302
1. Course outline
 Tentative schedule of lectures
2. Introduction
 What is analytical chemistry?
Chemical analysis is concerned with detecting or determining a specific component or the general
composition of a sample.
Qualitative analysis - to find out what constituents are in the sample.
- to see whether the target constituents of interest are present or not in the sample
Quantitative analysis - to determine how much of each constituent is in the sample.
Analytical data
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- solving chemical problems.
Where is analytical chemistry used?
Topical areas of interest
How to approach the course
Send me your e-mail addresses to:
edward_lai@carleton.ca
Course Website
developed by the Educational Development Centre
http://http-server.carleton.ca/~elai/
http://www.carleton.ca/~elai/
CHEM 2302
CHEM 2302* Analytical Chemistry I
Course Material
1
Course Marks on WebCT
Course Material
1 Course Outline
Introduction
All files are .PDF
2 Preparation for test on Chapters 1 2 3
3
Preparation for test on Chapters 1 2 3 (5th
edition)
4 Lab Manual 2005
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How to Approach the Course
 Attend class regularly.
 Study lecture notes with reference to the textbook after each
lecture.
 Prepare for lab experiments.
 See me about difficulties/problems.
 Do all assignments.
 Study hard for the quizzes and final exam.
Where is analytical chemistry used?
 inorganic, organic, physical and biological chemistry research
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research in biology, earth sciences, medicine and physics
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industrial quality control
-- relating chemical composition to physical properties
- drugs, pharmaceuticals, foods, polymers and plastic materials
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trouble-shooting in manufacturing industries -- solving problems with the aid of chemical data
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forensic chemistry
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environmental chemistry
-- making precise measurements that are required for the
determination of trace amounts of pollutants
Analytical chemists in industry are problem solvers
who use their chemical skills and analytical thinking to solve
problems :
They gather relevant background information,
think through what steps should be taken,
and develop a plan (including available resources)
before going to the lab.
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Objectives in Analytical Chemistry
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Technician level --
methods, principles, instruments (lab)
Chemistry 65.2302* and 65.2303*
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Chemist level --
method selection, parameter optimization,
data evaluation, results interpretation
Chemistry 65.3305* and 65.4301*
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Scientist level --
development of new techniques and methods,
publication of scientific papers
Graduate studies and research (M.Sc. and Ph.D.)
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3. Nomenclature (or terminology)
Sample
 a fraction of the material whose chemical composition is of interest
 Chemical analysis is usually performed on a sample
Analyte
 element / ion / compound, the concentration of which is to be determined
Analysis
 only samples are analyzed
 elements, ions and compounds are identified or determined (detected)
When the sample is nominally an element or compound, "analysis of an element or compound"
must be understood to mean the identification or determination of impurities.
Sample matrix
 the medium containing the analyte
 the part of the sample material that is not of interest in an analysis
Interferences
 other chemicals present in the sample that produce an effect upon the measurement and change
the signal when the analyte concentration remains unchanged.
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Send me your e-mail addresses to:
edward_lai@carleton.ca
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Advanced Photo-Oxidation Process for Ammonia Removal from Industrial Wastewater
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Standard Methods
http://www.AOAC.org
Groundwater and Wastewater Analyses
HYPERLINK
TO METHOD
METHOD TITLE
EPA Method 601
PURGABLE HALOCARBONS
EPA Method 602
PURGABLE AROMATICS
EPA Method 603
ACROLEIN AND ACRYLONITRILE
EPA Method 604
PHENOLS
EPA Method 604.1
DETERMINATION OF HEXACHLOROPHENE AND DICHLOROPHEN IN INDUSTRIAL AND
MUNICIPAL WASTEWATERS
EPA Method 605
BENZIDINES
EPA Method 606
PHTHALATE ESTERS
EPA Method 607
NITROSAMINES
EPA Method 608
ORGANOCHLORINE PESTICIDES AND PCB'S
EPA Method 608.2
ANALYSIS OF CERTAIN ORGANOCHLORINE PESTICIDES IN WASTEWATER BY GAS
CHROMATOGRAPHY
EPA Method 609
NITROAROMATICS AND ISOPHORONE
EPA Method 610
POLYNUCLEAR AROMATIC HYDROCARBONS
EPA Method 611
HALOETHERS
EPA Method 612
CHLORINATED HYDROCARBONS
EPA Method 613
DIOXIN
EPA Method 615
THE DETERMINATION OF CHLORONATED HERBICIDES IN INDUSTRIAL AND MUNICIPAL
WASTEWATER
EPA Method 616
C, H, AND O COMPOUNDS
EPA Method 617
THE DETERMINATION OF ORGANOHALIDE PESTICIDES AND PCBS IN INDUSTRIAL AND
MUNICIPAL WASTEWATER
EPA Method 618
DETERMINATION OF VOLATILE PESTICIDES IN MUNICIPAL AND INDUSTRIAL WASTEWATERS BY
GAS CHROMATOGRAPHY
EPA Method 619
DETERMINATION OF TRIAZINE PESTICIDES IN INDUSTRIAL AND MUNICIPAL WASTEWATER
EPA Method 620
DETERMINATION OF DIPHENYLAMINE IN MUNICIPAL AND INDUSTRIAL WASTEWATERS
EPA Method 622.1 THIOPHOSPHATE PESTICIDES
EPA Method 624
PURGABLE ORGANICS IN WATERS
EPA Method 625
SEMIVOLATILE ORGANICS IN WATERS
EPA Method 627
THE DETERMINATION OF DINITROANILINE PESTICIDES IN INDUSTRIAL AND MUNICIPAL
WASTEWATER
EPA Method 629
THE DETERMINATION OF CYANAZINE IN INDUSTRIAL AND MUNICIPAL WASTEWATER
EPA Method 631
THE DETERMINATION OF BENOMYL AND CARBENDAZIM IN INDUSTRIAL AND MUNICIPAL
WASTEWATER
EPA Method 632
THE DETERMINATION OF CARBAMATE AND UREA PESTICIDES IN INDUSTRIAL AND MUNICIPAL
WASTEWATER
EPA Method 632.1
ANALYSIS OF CARBAMATE AND AMIDE PESTICIDES IN WASTEWATER BY LIQUID
CHROMATOGRAPHY
EPA Method 633
THE DETERMINATION OF ORGANONITROGEN PESTICIDES IN INDUSTRIAL AND MUNICIPAL
WASTEWATER
EPA Method 634
DETERMINATION OF THIOCARBAMATE PESTICIDES IN INDUSTRIAL AND MUNICIPAL
WASTEWATERS BY GAS CHROMATOGRAPHY
EPA Method 635
DETERMINATION OF ROTENONE IN INDUSTRIAL AND MUNICIPAL WASTEWATERS BY LIQUID
CHROMATOGRAPHY
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EPA Method 636
DETERMINATION OF BENSULIDE IN INDUSTRIAL AND MUNICIPAL WASTEWATERS BY LIQUID
CHROMATOGRAPHY
EPA Method 637
DETERMINATION OF MBTS AND TCMTB IN MUNICIPAL AND INDUSTRIAL WASTEWATERS BY
LIQUID CHROMATOGRAPHY
EPA Method 638
DETERMINATION OF ORYZALIN IN INDUSTRIAL AND MUNICIPAL WASTEWATERS
EPA Method 639
DETERMINATION OF BENDIOCARB IN MUNICIPAL AND INDUSTRIAL WASTEWATERS BY LIQUID
CHROMATOGRAPHY
EPA Method 640
DETERMINATION OF MERCAPTOBENZOTHIAZOLE IN WASTEWATERS BY LIQUID
CHROMATOGRAPHY
EPA Method 641
ANALYSIS OF THIABENDAZOLE IN WASTEWATER BY LIQUID CHROMATOGRAPHY
EPA Method 643
ANALYSIS OF BENTAZON IN WASTEWATER BY LIQUID CHROMATOGRAPHY
EPA Method 644
ANALYSIS OF PICLORAM IN WASTEWATER BY LIQUID CHROMATOGRAPHY
EPA Method 645
ANALYSIS OF CERTAIN AMINE PESTICIDES AND LETHANE IN WASTEWATER BY GAS
EPA Method 646
ANALYSIS OF DINITRO AROMATIC PESTICIDES IN WASTEWATER BY GAS CHROMATOGRAPHY
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What instrumental methods (or analytical techniques) can you use for the following analysis?
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determination of calcium in Ca3(PO4)2
anions in tap / river water
fluoride in drinking water
cadmium, copper, lead and zinc in tap / river water
polycyclic aromatic hydrocarbons (PAHs) in environmental water samples
carbonyls in atmospheric aerosol and vehicle exhaust
chemical oxygen demand of ground / river water
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Chemistry 65.2302*
ANALYTICAL CHEMISTRY
LABORATORY MANUAL
2006 Fall
Page 3
EXPERIMENTS
1.
Ion Chromatography of Anions in Tap/River Water with Conductivity Detection.
2.
Determination of Fluoride in Drinking Water by Ion-Selective Electrode Potentiometry.
3.
Determination of Lead, Cadmium and Copper in Tap/River Water by Differential Pulse
Anodic Stripping Voltammetry.
4.
Determination of Copper and Zinc in Tap/River Water by Atomic Absorption Spectroscopy.
5.
Gas Chromatography of Polycyclic Aromatic Hydrocarbons with Flame Ionization
Detection.
6.
Monitoring of Carbonyls by 2,4-Dinitrophenylhydrazine Derivatization and Reversed-Phase
High Performance Liquid Chromatography.
7.
Chemical Oxygen Demand Assay by Standard Method 5200 D.
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Summary
Method
Analytes
Destructive /
Analytical
Non-destructive figures of merit
EDTA
complexometric
titration
HPLC
GC
Ion-selective
electrodes
Anodic stripping
voltammetry
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Standard Calibration Curve
A calibration curve is always prepared to establish a working
relationship between the analytical signal (that you measure using an
instrument) and the analyte concentration (that you prepare in
standard solutions).
This curve is required for you to determine the unknown analyte
concentration in the sample by using the instrument to measure a
signal for interpolation.
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