FUDR Dose Calculation Worksheet STEP ONE: [Prescribed dose of FUDR] x [weight in kg] x [pump volume] (usually .12 - .20 mg/kg) (16, 30, or 50 ml) Pump flow rate (0.1, 1.2 or 2.50 ml/day) = Total FUDR in mgs STEP TWO: Total FUDR in mgs FUDR concentration (usually 100mg/ml) = (Total volume of FUDR in mls) STEP THREE: Prescribed dose of dexamethasone (20mg unless otherwise specified) Concentration of dexamethasone (usually 4mg/ml or 5mg/ml) = (Total volume of Dex. In mls) STEP FOUR: 1000 units heparin x pump volume (16, 30, or 50 ml) Concentration of heparin available (must be 5000 units/ml or higher) = ( Total volume of heparin in mls) STEP FIVE: FUDR (mls) + Total volume of FUDR in mls + Dexameth (mls) Total volume of dexamethasone in mls + Heparin (mls) = Total drug vol + Total volume of heparin in mls = Total Drug Volume STEP SIX: Pump volume Pump volume (16, 30, or 50 mls) 2/6/2016 – – Total drug vol Total drug volume = = Saline (mls) Normal saline volume to QS Calculation Examples Patient weight: 64 kg FUDR Dose: 0.14 mg/kg Dexamethasone dose: 20 mg Heparin concentration: 10,000 units/mL Pump reservoir volume: 30mL FUDR Concentration : 100 mg/mL Concentration: 5 mg/mL Pump flow rate:1.3mL/day (.14 x64 x 30) 1.3 = 206.76 mg of FUDR total 206.76 100 mg/ml FUDR concentration = 2.06 ml total volume of FUDR 20 mg dexamethasone 5 mg/ml concentration = 4 ml total volume of dexamethasone (1000 units heparin x 30 mL pump volume) 10,000 = 3 ml total volume of heparin 2.06 mL FUDR + 4 mL dexamethasone + 2 mL heparin = 8.06 total drug volume 30 mL pump reservoir size – 8.06 total drug volume = 21.94 mL of normal saline. What would the calculation be for a patient who weighs 175 pounds with a 30 mL pump with a flow rate of 1.3 mL/day with an ordered dose of .18 mg/kg of FUDR? FUDR dose: 175 2.2 = 79.54 kg .18 mg/kg x 79.54 kg = 14.31 mg FUDR/day 14.31 mg FUDR/day x 30 mL pump volume = 429.5 mg FUDR total 429.5 mg FUDR 1.3 ml/day (pump flow rate) = 330.39 330.39 100 mg/mL FUDR concentration = 3.30 ml total volume of FUDR Heparin dose: 1000 units heparin x 30 mL pump volume = 30,000 units of heparin 30,000 units 5,000 units/mL heparin concentration = 6 mL total heparin volume Dexamethasone dose: 20 mg dexamethasone 4 mg/mL concentration of dexamethasone = 5 ml total volume of dexamethasone Final calculation: 3.30 mL total volume of FUDR + 6 mL total volume of heparin + 5 mL total volume of dexamethasone = 14.3 total volume of drug Pump reservoir volume 30 mL – 14.3 total drug volume = 15.7 ml normal saline. Great job! 2/6/2016