Curriculum Vitae
Young Kwok, M.D.
Associate Professor
Department of Radiation Oncology
University of Maryland School of Medicine
Date: April 3, 2014
Contact Information
Young Kwok, MD
Dept of Radiation Oncology
University of Maryland School of Medicine
22 South Greene St.
Baltimore, MD 21201 USA
Email: ykwok@umm.edu
Office: (410) 328-9134
Fax: (410) 328-5279
Education
1995 B.A.
1999
M.D.
Psychology, Johns Hopkins University, Baltimore, MD
Departmental and General Honors
Albert Einstein College of Medicine, Bronx, NY
Post Graduate Education and Training
2000 Internship
Internal Medicine, Beth Israel Medical Center, New York, NY
2004 Residency
Radiation Oncology, University of Maryland Medical Center, Baltimore, MD
Certifications
2006
American Board of Radiology
Medical Licensures
2004
2004
Maryland State License, active
Michigan State License, inactive
Employment History
Academic Appointment
2004-2011
Assistant Professor, Department of Radiation Oncology, UMSOM
2011-present
Associate Professor, Department of Radiation Oncology, UMSOM
Clinical Privileges
2004-Present
2004-Present
2004-2010
2004-2010
2004-Present
2008-Present
University of Maryland Medical Center, Baltimore, MD
Baltimore VA Medical Center, Baltimore, MD
Maryland General Hospital, Baltimore, MD
Montgomery General Hospital, Olney, MD
Howard County General Hospital, Columbia, MD
Baltimore-Washington Medical Center, Glen Burnie, MD
Professional Memberships
2000-2004
American College of Radiation Oncology
Young Kwok, M.D.
2000-2004
2000-Present
2003-Present
2004-Present
2004-Present
2004-2011
2009-Present
2011-Present
American College of Radiology
American Society for Therapeutic Radiology and Oncology
American Brachytherapy Society
American Society of Clinical Oncology
Radiation Therapy Oncology Group
Cancer and Leukemia Group B (CALGB)
Children’s Oncology Group
Alliance for Clinical Trials in Oncology (merged group of CALGB, NCCTG,
ACOSOG)
Honors and Awards
Undergraduate
1991-1995
Full Academic Scholarship
1991-1995
Academic Dean’s List
1995
General and Departmental Honors
Medical School
1998
Travel Grant: American Society of Hematology, Miami Beach, FL
Residency
2002
2003
2003-2004
Roentgen Resident/Fellow Research Award: Radiologic Society of North America,
Chicago, IL
Travel Grant: Radiation Therapy Oncology Group Meeting, New Orleans, LA
Chief Resident
Assistant Professor
2006
Teacher of the Year: Association of Residents in Radiation Oncology.
2008
Clinical Scholars Award: Cancer and Leukemia Group B, Chicago, IL
Associate Professor
2012
Outstanding Reviewer of 2012, International Journal of Radiation Oncology, Biology,
Physics
Clinical Activities
Clinical Expertise
Genito-urinary malignancies
Central nervous system malignancies
Pediatric malignancies
Lymphomas and leukemias
Technical Expertise
Intensity-Modulated Radiation Therapy (IMRT)
Image-Guided Radiation Therapy (IGRT)
Stereotactic Radiosurgery (SRS), Gamma-knife, Trilogy, Truebeam
Fractionated Stereotactic Radiation Therapy (FSRT)
Stereotactic Body Radiation Therapy (SBRT)
Interstitial/Intracavitary Brachytherapy
Scope of Clinical Practice
Large academic medical center
2
Young Kwok, M.D.
250-300 patient consultations per year
150-180 patients treated per year
Clinical Duties: 4 days/week, 12 months/year
Development of Clinical Programs
2004-Present Developed a high-risk prostate cancer program
Contribute the vast majority of patients to the Gamma Knife program
2004-Present Developed an active clinical trial programs in CNS, GU and Pediatric.
2009-Present Developed a pediatric oncology collaborative program with Children’s National Medical
Center, Washington DC
Clinical Trials
University of Maryland Medical Center Protocols
2005 – 2006
PI
Retrospective Chart Review of Patients who have undergone Permanent
Interstitial Prostate Brachytherapy to Study the Correlation Between PreOperative CT Scan Beams-Eye-View Prostate Volume with Real-Time
Intraoperative Ultrasound Prostate Volumes
2005 - 2006
PI
GCC 0501: Retrospective Review of stereotactic Radiosurgery Treatments of
Benign, Primary and Metastatic Lesions: A University of Maryland Experience.
2006 - 2011
Co-PI (PI: David Eisenman, MD)
Gamma Knife for Acoustic Neuroma
Role: Helped design study. Enroll patients. Will assist in analyzing and
publishing results.
2006 - present
PI
GCC 0605: Phase II Study Evaluating Bone Marrow-Sparing, Image-Guided
Pelvic Intensity-Modulated Radiotherapy (IMRT) with Cesium-131
Brachytherapy Boost, Adjuvant Chemotherapy, and Long-Term Hormonal
Ablation in Patients with High Risk, Non-Metastatic Prostate Cancer.”
2013 - present
PI
GCC 1224: Phase II Trial of Low-Dose Whole Brain Radiotherapy with
Concurrent Temozolomide and Adjuvant Temozolomide in Patients with NewlyDiagnosed Glioblastoma Multiforme
2013 - present
PI
GCC 1328: Retrospective Analysis of Salvage External Radiation Therapy in
Patients with Recurrent Prostate Cancer after Brachytherapy
Principle Investigator of National/International Protocols
2013 - present
Co-Chair, Alliance (CALGB)
RTOG 1115: Phase III Trial of Dose Escalated Radiation Therapy and Standard
Androgen Deprivation Therapy (ADT) with a GnRH Agonist vs. Dose Escalated
Radiation Therapy and Enhanced ADT with a GnRH Agonist and TAK-700 for
Men with High Risk Prostate
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Young Kwok, M.D.
Institutional Principle Investigator of National/International Protocols
2006 - 2009
RTOG 0320: A Phase III Trial Comparing Whole Brain Radiation and
Stereotactic Radiosurgery Alone Versus with Temozolomide or Erlotinib in
Patients with Non Small Cell Lung Cancer and 1-3 Brain Metastases
2007 - 2009
RTOG 0415: A Phase III Randomized Study of Hypofractionated 3DCRT/IMRT versus Conventionally fractionated 3D-CRT/IMRT in Patients with
Favorable-risk Prostate Cancer.
2005 - 2009
RTOG 0424: A Phase II Study of a Temozolomide-Based Chemoradiotherapy
Regimen for High Risk Low-Grade Gliomas
2008 - present
RTOG 0526: A Prospective Phase II Trial of Transperineal Ultrasound-Guided
Brachytherapy for Locally Recurrent Prostate Adenocarcinoma Following
External Beam Radiotherapy
2008 - present
RTOG 0534: A Phase III Trial of Short Term Androgen Deprivation with Pelvic
Lymph Node or Prostate Bed Only Radiotherapy (SPORT) in Prostate Cancer
Patients with a Rising PSA after Radical Prostatectomy
2008 - 2010
RTOG 0614: A Randomized, Phase III, Double-Blind, Placebo-Controlled Trial
of Memantine for Prevention of Cognitive Dysfunction in Patients Receiving
Whole-Brain Radiotherapy
2008 - 2009
RTOG 0513: A Phase I/II Trial of Temozolomide, Motexafin Gadolinium, and
60 Gy Fractionated Radiation for Newly Diagnosed Supratentorial Glioblastoma
Multiforme
2008 - 2010
RTOG 0621: Adjuvant 3DCRT/IMRT in Combination with Androgen
Suppression and Docetaxel for High Risk Prostate Cancer Patients PostProstatectomy: A Phase II Trial
2009 - 2011
RTOG 0825: Phase III Double-Blind Placebo-Controlled Trial of Conventional
Concurrent Chemoradiation and Adjuvant Temozolomide plus Bevacizumab
versus Conventional Concurrent Chemoradiation and Adjuvant Temozolomide in
Patients with Newly Diagnosed Glioblastoma
2009 - 2012
RTOG 0539: Phase II Trial of Observation for Low-Risk Meningiomas and of
Radiotherapy for Intermediate and High-Risk Meningiomas
2010 - present
RTOG 0815: Phase III Prospective Randomized Trial of Dose-Escalated
Radiotherapy with or without Short-Term Androgen Deprivation Therapy for
Patients with Intermediated-Risk Prostate Cancer.
2010 - 2012
RTOG 0831: A Randomized, Double-Blinded, Placebo-Controlled Phase III
Trial to Evaluate the Effectiveness of a Phosphodiesterase 5 Inhibitor, Tadalafil,
in Prevention of Erectile Dysfunction in Patients Treated with Radiotherapy for
Prostate Cancer.
2011 - present
RTOG 0929: A Randomized Phase I/II Study of ABT-888 in Combination With
Temozolomide in Recurrent (Temozolomide Resistant) Glioblastoma
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Young Kwok, M.D.
2011 - present
RTOG 0924: Androgen Deprivation Therapy and High Dose Radiotherapy With
or Without Whole-Pelvic Radiotherapy in Unfavorable Intermediate or Favorable
High Risk Prostate Cancer: A Phase III Randomized Trial
2011 – present
RTOG 0938: A Randomized Phase II Trial Of Hypofractionated Radiotherapy
For Favorable Risk Prostate
2013 - present
RTOG 0913: Phase I/II Trial of Concurrent RAD001 (Everolimus) With
Temozolomide/Radiation Followed by Adjuvant RAD001/Temozolomide in
Newly Diagnosed Glioblastoma
2013 - present
RTOG 1205: Randomized Phase II Trial of Concurrent Bevacizumab and ReIrradiation Versus Bevacizumab Alone as Treatment for Recurrent Glioblastoma
Institutional Co-Principle Investigator of National/International Protocols
2002 - 2008
RTOG 0126: A Phase III Randomized Study of High Dose 3D-CRT/IMRT
versus Standard Dose 3D-CRT/IMRT in Patients Treated for Localized Prostate
Cancer.
2003 - present
RTOG 0232: A Phase III Study Comparing Combined External Beam Radiation
and Transperineal Interstitial Permanent Brachytherapy with Brachytherapy
Alone for Selected Patients with Intermediate Risk Prostatic Carcinoma.
Administrative Service
Institutional (UMSOM)
2004-Present Tumor Boards
2004-Present GU Tumor Board (Leader/Coordinator since March 2007)
2004-Present Solid Tumor Board
2004-Present CNS Tumor Board
2004-Present Lymphoma Tumor Board
2004-Present Pediatric Tumor Board
2007-2008
Base of Skull Tumor Board
2007-2009
Head and Neck Tumor Board
2004-Present Committees
2005-2009
Cancer Review Committee
2005-2011
Technology Review Committee
2010-2013
Radiation Oncology IT Committee
2010-2011
University of Maryland Dosimetry School Curriculum Committee
2010-Present University of Maryland Dosimetry School Advisory Committee
2011-Present Brachytherapy Committee
2004-Present Internal Residency/Fellowship Review
2004 Urology
2005 Interventional Cardiology
2004-Present UMSOM Admissions—Applicant Interviews, 10-15 per year
2004-Present Radiation Oncology Electronic Library
2005-Present Institutional Review Board, IRB Panel #4 (committee #1 starting 2013)
2007-Present Ask the Expert (www.umm.edu website)
2007-Present Spine-directed Oncology Program.
http://www.umgcc.org/brain_tumor_center/spine-directed-oncology.htm
2009-Present Gamma Knife Center
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Young Kwok, M.D.
2010-Present
2008
2008-2009
2009-2012
2009-2011
2011-2013
2012
2013
2013
2013
http://www.umm.edu/gammaknife/index.htm
Prostate Seed Implant
http://www.umgcc.org/gu_program/psi.htm
Department of Radiation Oncology Research Retreat (April 2, 2008)
Coordinated a research retreat, which included the subdivisions of physics, biology, and
clinical faculty, with the following objectives:
1. To identify barriers and limitations that prevent effective clinical/translational
research
2. To identify strategies to optimize effective interdepartmental research collaboration
3. To identify strategies to optimize effective inter-institutional research collaboration
Acting Director of Clinical Research
Department of Radiation Oncology, University of Maryland Medical Center
Associate Director of Clinical Research
Department of Radiation Oncology, University of Maryland Medical Center
Cancer Interest Group
Univ of Maryland-Baltimore/University of Maryland-College Park annual seed
competition, reviewer
Department of Radiation Oncology, Practice Guidelines
Jan 17, 2012 CNS Cancers
Mar 27, 2012 Lymphomas
June 5, 2012 Gamma Knife Stereotactic Radiosurgery
Associate Director of Residency
Department of Radiation Oncology, University of Maryland Medical Center
Director of Medical Student Rotations
Department of Radiation Oncology, University of Maryland Medical Center
Department of Radiation Oncology--Appointments, Promotions, Tenure Committee
2013 Nilesh Mistry, PhD (Instructor to Assistant Professor)
Mariana Guerrero, PhD (Clinical Assistant to Clinical Associate Professor)
Wei Lu, PhD (Assistant to Associate Professor)
Yildirim Mutaf, PhD (Assistant to Associate Professor)
Warren D’Souza, PhD (Associate Professor to Professor)
2014 Hao (Howard) Zhang, PhD (Instructor to Assistant Professor)
Local/Regional
2004-2007
Cancer Committee, Baltimore VA Medical Center, Baltimore, MD
2008-2009
White Oak Seminar Series: Coordinated a series of Radiation Oncology
presentations at the FDA: Center for Devices and Radiological Health—The Federal
Research Center @ White Oak, Silver Springs, MD
March 26, 2008
Speaker:
Young Kwok, M.D.
Topic: Recent Advances in Radiation Oncology
April 30, 2008
Speaker:
Michael Garofalo, M.D.
Topic: Liver-directed Therapy
May 28, 2008
Speaker:
Majid Mohiuddin, M.D.
Topic: Recent Advances in Breast Cancer
August 27, 2008
Speaker:
William Regine, M.D.
Topic: Brain Metastases Management
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Young Kwok, M.D.
September 24, 2008
2009-Present
Speaker:
Anil Dhople, M.D.
Topic: Stereotactic Body Radiation Therapy
February 25, 2009
Speaker:
Pradip Amin, M.D.
Topic: Brachytherapy
Pediatric Tumor Boards, Children’s National Medical Center (Washington, DC)
2009-Present Pediatric Solid Tumor Board
2009-Present Pediatric CNS Tumor Board
National/International
2011-Present Editorial Board, International Journals
2011-present The World Scientific Journal
2003-Present
Ad Hoc Reviewer, International Journals
2003-present Technology in Cancer Research and Treatment
2004-present American Journal of Clinical Oncology
2005-present International Journal of Radiation Oncology Biology Physics
2005-present Journal of Clinical Oncology
2006-present Spinal Cord
2007-present International Journal for Quality in Health Care
2007-present The Lancet Oncology
2007-present Cancer
2008-present Lung Cancer
2008-present Molecular Cancer Therapeutics
2011-present Mayo Clinic Proceedings
2005-11
Genito-urinary & Radiation Oncology Committees, Cancer and Leukemia
Group B (CALGB), Chicago, Il
Genito-urinary Committee
Radiation Oncology Committee
2006-2007
University of Maryland Annual Radiobiology, Physics Review Course:
Annual review course for the Radiation Oncology Written Board Exam attended by a
majority of residents throughout the country.
April 28-30, 2006
Co-coordinator
May 3-6, 2007
Co-coordinator
2007-present
American Board of Radiology (Radiation Oncology)
2007 Genito-urinary written board examination writer
2008 Genito-urinary written board examination writer
2011-Present
Alliance for Clinical Trials in Oncology (merged group of CALGB, NCCTG, ACOSOG)
Genito-urinary Committee
Radiation Oncology Committee
Teaching Service
Medical School Lectures (UMSOM, 15-20 students)
2001-11
Discussion Group Facilitator for second year medical school small group in
oncology, one 2 hour class per year
Clinical Teaching Duties (University of Maryland Medical Center)
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Young Kwok, M.D.
2004-Present
Attending Physician, inpatient/outpatient consults, outpatient clinic
1 resident, 10 hours/day, 4 days/week, 10-12 months/year
Graduate School Lectures (University of Maryland, Baltimore, 10-15 students)
2008
GPIL 665 course - Special Topics in Cancer Biology
Contemporary Management of Glioblastoma. 1.5 hr lecture--October 27, 2008
Course Director:
Feyruz Rassool, Ph.D.
Graduate Student Mentees (2hr/week for 2 weeks for each student):
Dipika Germani, Final Project: Alternatives strategies in overcoming imatinib
resistance in chronic myeloid leukemia patients.
Amanda Graner, Final Project: The Role of the t(4; 14)(p16; q32) translocation
in multiple myeloma
2009
GPIL 665 course - Special Topics in Cancer Biology
CNS Tumor: Clinical Management. 1.5 hr lecture--October 26, 2009
Course Director:
Feyruz Rassool, Ph.D.
2010
GPIL 665 course - Special Topics in Cancer Biology
CNS Tumor: Clinical Management. 1.5 hr lecture—October 29, 2010
Course Director:
Feyruz Rassool, Ph.D.
2011
GPIL 665 course - Special Topics in Cancer Biology
CNS Tumor: Clinical Management. 1.5 hr lecture—November 14, 2011
Course Director:
Feyruz Rassool, Ph.D.
2012
GPIL 665 course - Special Topics in Cancer Biology
CNS Tumor: Clinical Management. 1.5 hr lecture—November 26, 2012
Course Director:
Feyruz Rassool, Ph.D.
2013
GPIL 665 course - Special Topics in Cancer Biology
CNS Tumor: Clinical Management. 1.5 hr lecture—November 25, 2013
Course Director:
Feyruz Rassool, Ph.D.
 Wrote and graded exams
Ph.D. Dissertation Committee
2008-2012
(2 hour/month)
Candidate:
Nneka Onwudiwe, University of Maryland School of Pharmacy
Title: Breast Conserving Surgery: Event Free Survival and Costs Subsequent to
Radiation Therapy
Advisors:
Ebere Onukwugha, Ph.D., C Daniel Mullins, Ph.D., Young Kwok, M.D.
Proposal Defense: May, 2009
Ph.D. Thesis Defense: March 2012
Resident Lectures, Department of Radiation Oncology (1 hour, 10-15 Residents and Students)
April 20, 2005
Pediatric Medulloblastoma
June 12, 2007
Metastatic Spinal Cord Compression
Nov 20, 2007
Medulloblastoma
Dec 4, 2007
Predictors of Outcome in Prostate Cancer
Jan 2, 2008
Jeopardy: Genito-urinary Cancers
Oct 7, 2008
Contemporary Management of Non-metastatic Prostate Cancer
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Young Kwok, M.D.
Oct 28, 2008
April 22, 2009
April 29, 2009
Oct 7, 2009
March 17, 2010
October 5, 2010
May 4, 2011
May 11, 2011
March 28, 2012
May 9, 2012
March 20, 2013
May 8, 2013
Sept 19, 2013
Jeopardy: Genito-urinary Cancers
Radiation Sensitizers in Metastasis
Jeopardy: Central Nervous System
High-Risk Prostate Cancer
Pediatric Ependymoma
“Tie Breakers” in Prostate Cancer
Pediatric Hodgkin’s Disease—Late Morbidity and Mortality
Alternative Dose Delivery Systems
Post-operative Radiation Therapy for Prostate Cancer
Alternative Dose Delivery Systems
Pediatric Jeopardy
Alternative Dose Delivery Systems
Post-Prostatectomy Radiation Therapy
University of Maryland Dosimetry School Lectures (1 hour, 2 dosimetry students)
October 25, 2004
CNS Dosimetry-Treatment Planning
April 23, 2008
CNS Tumors
November 5, 2008
Base of Skull Tumors I
November 12, 2008
Base of Skull Tumors II
March 17, 2010
CNS–Glioblastoma Multiforme
April 20, 2011
CNS–Glioblastoma Multiforme
February 7, 2013
CNS–Glioblastoma Multiforme
February 11, 2013
GU-Brachytherapy
March 11, 2013
Prostate Cancer
Resident Mock Oral Preparatory Exams, Department of Radiation Oncology (1 hour,
exam/feedback)
Sept 21, 2005
Genito-urinary. Anil Dhople M.D.
Oct 24, 2006
Genito-urinary. Todd Flannery M.D.
Jan 17, 2007
Central Nervous System. Todd Flannery M.D.
Nov 28, 2007
Genito-urinary. Ashish Patel M.D.
Jan 21, 2010
Central Nervous System, Geoffrey Neuner, M.D.
April 28, 2010
Central Nervous System/Pediatrics, Ashish Patel M.D.
April 28, 2010
Central Nervous System/Pediatrics, Ali Mirmiran M.D.
October 25, 2010
Genito-urinary, Usama Mahmood, M.D.
April 27, 2011
Central Nervous System/Pediatrics
Navesh Sharma, M.D.
Russell Hales, M.D. (Johns Hopkins)
Kristen Redmon, M.D. (Johns Hopkins)
Susannah Yovino, M.D. (Johns Hopkins)
May 4, 2011
Central Nervous System/Pediatrics, Genito-urinary
Navesh Sharma, M.D.
Matthew Koshy, M.D.
Kristen Redmon, M.D. (Johns Hopkins)
April 9, 2012
Central Nervous System/Pediatrics, Sarah Grabowski, M.D.
May 11, 2012
Central Nervous System/Pediatrics, Genito-urinary
Geoffrey Neuner, M.D. (GBMC)
Usama Mahmood, M.D. (MD Anderson Cancer Center)
Randi Cohen, M.D.
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Young Kwok, M.D.
June 4, 2012
June 13, 2012
Oct 3, 2012
April 19, 2013
May 1, 2013
Genito-urinary, Grace Kim, M.D.
Central Nervous System/Genito-urinary, Zain Husain, M.D.
Central Nervous System/Genito-urinary, Elizabeth Nichols, M.D.
Central Nervous System/Pediatrics, Genito-urinary
Grace Kim, M.D. (Duke)
Zain Husain, M.D. (Yale)
Lara Bonner Millar, M.D. (Eastern Virginia)
Genito-urinary, Benjamin Laser, M.D.
Student Research Sponsorships/Mentorships (2 hours/week)
2002-2003
Stephen Ronson, MS IV (University of Maryland School of Medicine)
Topic: Incidence and temporal pattern of hematuria and proteinuria in men treated with
permanent interstitial prostate brachytherapy.
Results:
 Presented at the American Radium Society, Houston, Tx, April 2003.
 Matched residency program in Radiation Oncology at Loma Linda Hospital, CA.
2003-2004
Neeraja Murali, BA (University of Maryland College Park)
Topic: Long-term Results of Gamma Knife Stereotactic Radiosurgery for Nonfunctioning Pituitary Adenomas.
Results:
 Presented at the American Society of Therapeutic Radiology and Oncology, Atlanta,
Ga October 2004.
 Entered graduate program in Epidemiology at Emory University, GA.
2003-2004
Susannah Yovino, MS IV (University of Maryland School of Medicine)
Topic: Preoperative Anemia is Associated with Decreased Survival in Patients with
Stage I and II Non-Small-Cell Lung Cancer Treated with Surgery.
Results:
 Presented at the American Society of Therapeutic Radiology and Oncology, Atlanta,
Ga October 2004
 Manuscript published in International Journal of Radiation Oncology Biology
Physics, 2005.
 Matched residency program in Radiation Oncology at University of Maryland School
of Medicine, MD.
2005-2007
Owen Thomas, MS III (University of Maryland School of Medicine)
Topic: Long-term outcome of Gamma-Knife stereotactic radiosurgery for brain
metastasis from radio-resistant tumors (melanoma, sarcoma, renal-cell carcinoma).
Results:
 Presented at the Radiological Society of North America, Chicago, Il, November 2006
 Matched in residency program in Radiation Oncology at Johns Hopkins Hospital,
MD
2005-2007
Lara Bonner, MS III (University of Maryland School of Medicine)
Topic: Hematuria and Proteinuria in men treated with prostate brachytherapy.
Results: Matched in residency program in Radiation Oncology at University of
Pennsylvania Hospital, PA
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Young Kwok, M.D.
2006-2007
Elizabeth Nichols, MS III (University of Maryland School of Medicine)
Topic: Long-term outcome of patients with vestibular schwannoma treated with gamma
Knife stereotactic radiosurgery.
Results:
 Matched in residency program in Radiation Oncology at University of Maryland
Medical Center, MD
2009-2010
Tejan Diwanji, MS I
Topic: Long-term outcome of multiple sclerosis patients with trigeminal neuralgia
treated with Gamma-Knife stereotactic radiosurgery.
Results:
 Summer Fellowship Award in Radiation Oncology ($2500). Department of Radiation
Oncology, University of Maryland School of Medicine
 Presented at the American Society of Therapeutic Radiology and Oncology, San
Diego, Ca October 2010
2009-2010
Sonu Bassi, Severn High School Student
Topic: Long-Term Results of a Prospective, Phase II Study of Long-term Androgen
Ablation,Pelvic Radiotherapy, Brachytherapy Boost and Adjuvant Docetaxel in Patients
with High-Risk Prostate Cancer
Results:
 Manuscript accepted to the International Journal of Radiation Oncology Biology
Physics, 2010.
 Early admission to Johns Hopkins University
2010-present
Andrew Saltos, MS III
Topic: Outcomes of AVM patients treated with Gamma Knife.
Results:
 Abstract accepted to the American Society for Radiation Oncology, 2011 annual
meeting.
 Manuscript published in Journal of Neurosurgery, 2012
2011-2012
Kevin Quinn, MS I
Topic: Neurocognitive Function in Long-Term Survivors of Whole Brain Radiation
Results:
 American Brain Tumor Association Medical School Summer Fellowship ($3000).
Department of Radiation Oncology, University of Maryland School of Medicine.
2012-present
Moshe Meister, MS I
Topic: High-Risk Prostate Cancer, Salvage therapy for Brachytherapy Failures
Results:
 Oral Presentation, American Society for Radiation Oncology, 2013 annual meeting
 Department of Radiation Oncology Summer Research Fellowship 2013
 Submitted abstract for American Society for Radiation Oncology, 2014 annual
meeting
2012-present
Matthew Ferris, MS III
Topic: High-Risk Prostate Cancer, Preliminary Results of GCC 0605
Results:
 Oral Presentation, American Society for Radiation Oncology, 2013 annual meeting
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Young Kwok, M.D.

2013-present
Matched for Radiation Oncology at Emory University
Shivum Kumar, High School Student
Topic: Proton Beam Therapy in Pediatric Patients: Photon vs Protons
Radiation Oncology Resident Research Sponsorships/Mentorships, Department of Radiation
Oncology (2 hours/week)
2003-2004
Pinaki Dutta, MD (University of Pennsylvania Hospital)
Topic: Comparison of Repeat GK-SRS for Refractory or Recurrent Trigeminal
Neuralgia: Does Dose Matter?
Results:
 Presented at the American Society of Therapeutic Radiology and Oncology, Atlanta,
Ga, October 2004.
2004-2005
Anil Dhople, MD
Topic: Evaluation of Efficacy and Quality of Life in Patients with
Atypical Facial Pain Treated with Gamma-Knife Stereotactic Radiosurgery.
Results:
 Presented at the American Society of Therapeutic Radiology and Oncology, Denver,
Co, October 2005
 Manuscript published. International Journal of Radiation Oncology Biology Physics,
2006.
2005-2006
Shilpen Patel, MD
Topic: Evaluating the influence of dose-rate on outcome with gamma-knife stereotactic
radiosurgery in the treatment of trigeminal neuralgia.
Results:
 Presented at the American Society of Therapeutic Radiology and Oncology, Denver,
Co. October 2005.
2005-2006
Susannah Yovino, MD
Topic: Long-term outcome of breast cancer patients treated with Gamma-Knife
stereotactic radiosurgery for brain metastasis
Results:
 Presented at the Radiologic Society of North America, Chicago 2006.
2005-2006
Kathleen Settle, MD
Topic: A Volumetric Study of Needle’s Eye View CT scan in Predicting Pubic Arch
interference and Intra-operative Prostate Volume in Men Undergoing Permanent
Interstitial ProstateBrachytherapy.
2005-2007
Anil Dhople, MD
Topic: Long-term outcome of Gamma-Knife stereotactic radiosurgery for brain
metastasis from radio-resistant tumors (melanoma, sarcoma, renal-cell carcinoma).
Results:
 Presented at the Radiological Society of North America, Chicago, Il, November 2006
2005-2007
Todd Flannery, MD
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Young Kwok, M.D.
Topic: The Impact of Definitive Thoracic Management on Long-Term Survival in
Patients with Synchronous, Solitary Brain Metastases from Non-Small Cell Lung Cancer
Treated with Stereotactic Radiosurgery.
Results:
 Presented at the American Society of Therapeutic Radiology and Oncology,
Philadelphia, PA 2006
 Manuscript published International Journal of Radiation Oncology Biology Physics,
2008.
2005-2008
Todd Flannery, MD
Topic: Long-term Results of Intermediate and High-Risk Prostate Cancer Patients
Treated with Prostate Brachytherapy
Results:
 Presented at the American Brachytherapy Society, Philadelphia, PA, May 2006
 Resident Travel Award for Dr. Flannery
2007-2008
Usama Mahmood, MD
Topic: Dosimetric Analysis of Cesium-131 Brachytherapy.
Results:
 Presented at the American Brachytherapy Society, Boston, MA, May 2008.
2007-2009
Ali Mirmiran, MD
Topic: Long-term Toxicity Data of a Prospective Phase I/II Trial of Concurrent Paclitaxel
and Radiation for High-risk or Post-operative Prostate Cancer.
Results:
 Presented at American Society of Therapeutic Radiology and Oncology, Boston,
MA, 2008.
2007-2009
Ali Mirmiran, MD
Topic: Long-Term Results of a Prospective, Phase II Study of Long-term Androgen
Ablation, Pelvic Radiotherapy, Brachytherapy Boost and Adjuvant Docetaxel in Patients
with High-Risk Prostate Cancer
Results:
 Manuscript accepted to International Journal of Radiation Oncology Biology Physics,
2010.
2007-2010
Ashish Patel, MD
Topic: University of Maryland Experience of Gliasite Brachytherapy in Recurrents
High-grade Gliomas.
Results:
 Presented at the Radiologic Society of North America, Chicago, Il, 2008.
2008-2010
Matthew Koshy, MD
Topic: Utilization and Impact of Radiation Therapy in Stage I and II Hodgkin’s Disease
Results:
 Presented at the American Radium Society, Cancun, Mexico, May 2010
 Young Investigator Award
 Will be presented at the American Society of Therapeutic Radiology and Oncology,
San Diego, CA, October 2010
13
Young Kwok, M.D.

Manuscript accepted to International Journal of Radiation Oncology Biology Physics,
2010.
2009-2010
Grace Kim, MD
Topic: Outcomes of AVM patients treated with Gamma Knife.
2011-present
Elizabeth Nichols, MD
Topic: Brain Metastasis—Perez Book Chapter update
2013-present
Michael Rutenberg, M.D., Ph.D.
Topic: Salvage external beam radiation in prostate brachytherapy failures
Results:
 Submitted abstract for American Society for Radiation Oncology, 2014 annual
meeting
2013-present
Alexander Engelman, M.D.
Topic: HIV and Prostate Cancer; Long Term Update of GCC 0166—High Risk Prostate
Cancer
Results:
 Submitted abstracts for American Society for Radiation Oncology, 2014 annual
meeting
2013-present
James Snider, M.D.
Topic: Long Term Update of GCC 0166—High Risk Prostate Cancer
Results:
 Submitted abstract for American Society for Radiation Oncology, 2014 annual
meeting
Clerkship Director, Children’s National Medical Center (Washington, DC) Pediatric Oncology
Fellows (40 hours/week)
May 10-14, 2010
Fellow: Yaser Diab, M.D.
June 28-July 2, 2010
Fellow: Andrzek Rochowski, M.D.
June 28-July 2, 2010
Fellow: Helkha Peredo-Pinto, M.D.
July 26-30, 2010
Fellow: Burak Gumuscu, M.D
March 11-18, 2011
Fellow: Leslie Doros, M.D.
March 11-18, 2011
Fellow: Theresa Watson, M.D.
June 27-July 1, 2011
Fellow: Karim Sadak, M.D.
August 15-19, 2011
Fellow: Caitlin Neri, M.D.
July 23-27, 2012
Fellow: Surbhi Saini, M.D.
July 23-27, 2012
Fellow: Megha Kaushal, M.D.
July 31-Aug 3, 2012
Fellow: Violet Fernandes, M.D.
July 31-Aug 3, 2012
Fellow: Payal Khincha, M.D.
July 29-Aug 2, 2013
Fellow: Nicole Drezner, M.D.
July 29-Aug 2, 2013
Fellow: Bahey Salem, M.D.
August 19-23, 2013
Fellow: Ekta Kapadia
August 19-23, 2013
Fellow: Sucharita Bhaumik
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Young Kwok, M.D.
Grant Support
June 2006 – June 2011
Aug 2008 – Aug 2010
PI (5 %)
Phase II Study Evaluating Bone Marrow-Sparing, Image-Guided Pelvic
Intensity-Modulated Radiotherapy (IMRT) with Cesium-131
Brachytherapy Boost, Adjuvant Chemotherapy, and Long-Term
Hormonal Ablation in Patients with High Risk, Non-Metastatic Prostate
Cancer.
Industry Grant: Isoray Corp., Richland, WA
Total Direct and Indirect Costs: $200,000
PI (0 %)
A Phase I Study Evaluating Escalating Doses of Docetaxel
Concurrently with Bone Marrow-Sparing, Image-Guided Pelvic
Intensity-Modulated Radiotherapy (IMRT) and Long-Term
Androgen Ablation in Patients with High-Risk, Non-Metastatic
Prostate Cancer.
Seed Grant: Cancer and Leukemia Group B (CALGB)
Total Direct and Indirect Costs: $88,000
Sept 2010 – Sept 2011
Co-PI (0 %; PI – Rao Gullapalli, PhD)
GCC 1008: Neuroimaging Correlates in Evaluating Cognitive Function
Following Radiation Therapy.
U of MD Dept of Radiation Oncology Pilot Project Project Award
Total Direct and Indirect Costs: $50,000 (no salary, imaging only)
Pending CRC/IRB approvals
Role: Assisted in the design of the study. Will enroll patients. Will
assist in analyzing and publishing results.
Sept 2010 – Sept 2011
Co-PI (0 %; PI – France Carrier, PhD)
Radiosensitizing Effect of Histone Deacetylase Inhibitors for the
Treatment of Glioblastoma Multiforme with Low-Dose Fractionated
Radiation Therapy (LDFRT) in Combination with Radiation Therapy
U of MD Dept of Radiation Oncology Pilot Project Award
Total Direct and Indirect Costs: $50,000 (post-doc support)
Role: Assisted in designing the basic science research. Based on these
results, phase I/II trial was designed—currently enrolling.
Publications
Peer-Reviewed Journal Articles
1. Kwok Y, DiBiase S, Amin P, Naslund M, Jacobs S. Risk group stratification in patients undergoing
permanent I-125 prostate brachytherapy as monotherapy. International Journal of Radiation
Oncology Biology Physics 2002, 53(3), 588-594.
2. Flannery T, Suntharalingam M, Kwok Y, Koffman B, Amin P, Chin L, Nicol B, Fowler B, Young
AB, Regine W. Gamma Knife stereotactic radiosurgery for synchronous versus metachronous
solitary brain metastases from non-small cell lung cancer. Lung Cancer 2003, 42, 327-333.
3. Thomas L, Kwok Y, Edelman M. Management of paraneoplastic syndromes in lung cancer. Current
Treatment Options in Oncology 2004, 5(1), 51-62.
4. Herman JM, Petit JH, Amin P, Kwok Y, Dutta P, Chin LS. Repeat gamma knife radiosurgery for
refractory or recurrent trigeminal neuralgia: Treatment outcomes and quality of life assessment.
International Journal of Radiation Oncology Biology Physics 2004, 59(1), 126-133.
15
Young Kwok, M.D.
5. Garofalo M, Kwok Y, Regine WF. The Evolving Role of Adjuvant Postoperative Radiation Therapy.
Surgical Oncology Clinics of North America 2004 Oct;13(4):589-604, viii.
6. Patel AB, Edelman MJ, Kwok Y, Krasna M, Suntharalingam M. Predictors of acute esophagitis in
patients with non-small cell lung carcinoma treated with concurrent chemotherapy and
hyperfractionated radiation therapy followed by surgery. International Journal of Radiation Oncology
Biology Physics 2004 Nov;60(4),1106-12.
7. DiBiase S, Kwok Y, Yovino S, Arena C, Temple R, Regine W, Amin P, Chin L. Factors predicting
local tumor control after gamma knife stereotactic radiosurgery for benign intracranial meningiomas.
International Journal of Radiation Oncology Biology Physics 2004 Nov 15;60(4):1106-12.
8. Kwok Y, Regine WF, Patchell RA. Radiation therapy alone for spinal cord compression: time to
improve upon a relatively ineffective status quo. Journal of Clinical Oncology 2005 May
20;23(15):3308-10. Epub 2005 Feb 28.]
9. Yovino S, Kwok Y, Krasna M, Bangalore M, Suntha M. An association between preoperative
anemia and decreased survival in early-stage non-small cell lung cancer treated with surgery alone.
International Journal of Radiation Oncology Biology Physics 2005 Aug 1;62(5):1438-4.
10. Ma L, Kwok Y, Chin LS, Simard JM, Regine WF. Concomitant GRID boost for Gamma Knife
radiosurgery. Medical Physics 2005 Nov;32(11):3419-23.
11. Ma L, Kwok Y, Chin LS, Yu C, Regine WF. Comparative analyses of linac and Gamma Knife
radiosurgery for trigeminal neuralgia treatments. Phys Med Biol 2005 Nov 21;50(22):5217-27. Epub
2005 Oct 24.
12. D’Souza W, Kwok Y, DeYoung C, Zacharapoulos N, Pepelea M, Klahr P, and Yu CX. Gated CT
imaging using a free-breathing respiration signal from flow-volume spirometry. Medical Physics
2005 Dec;32(12):3641-49.
13. Kwok Y, DeYoung C, Garofalo M, Dhople A, and Regine W. Radiation Oncology Emergencies.
Hematology/Oncology Clinics of North America April 2006;20(2):505-522.
14. Kwok Y, Tibbs PA, Patchell RA. Clinical approach to metastatic epidural spinal cord compression.
Hematology/Oncology Clinics of North America Dec 2006;20(6):1297-1305.
15. D’Souza W, Nazareth D, Zhang B, Deyoung C, Suntharalingam M, Kwok Y, Yu CX, and Regine W.
The use of gated and 4D CT imaging in planning for stereotactic body radiation therapy. Medical
Dosimetry 2007 Summer;32(2):92-101.
16. Dhople A, Kwok L, Chin L, Shepard D, Slawson R, Amin P, and Regine W. Efficacy and quality of
life outcomes in patients with atypical trigeminal neuralgia treated with gamma-knife radiosurgery.
Int J Radiat Oncol Biol Phys 2007;69(2):397-403. Epub 2007 Apr 30.
17. Flannery TW,Suntharalingam M, Regine WF, Chin LS, Krasna MJ, Shehata MK, Edelman MJ,
Kremer M, Patchell RA, and Kwok Y. Long-term survival in patients with synchronous, solitary
brain metastasis from non-small cell lung cancer treated with radiosurgery. Int J Radiat Oncol Biol
Phys 2008 Sept 1;72(1):19-23. Epub 2008 Feb 13.
18. Dhople AA, Adams JR, Maggio WW, Naqvi SA, Regine WF, and Kwok Y. Long Term Outcomes
of Gamma-Knife Radiosurgery for Classic Trigeminal Neuralgia: Implications of Treatment and
Critical Review of the Literature. J Neurosurg 2009: 1-8. Epub 2009 March 27.
19. Settle K, Taylor R, Wolf J, Kwok Y, Cullen K, Carter K, Ord R, Zimrin A, Strome S, and
Suntharalingam M. Race impacts outcome in stage III/IV squamous cell carcinomas of the head and
neck after concurrent chemoradiation therapy. Cancer 2009; 115(8):1744-52.
20. Yovino S, Settle K, Taylor R, Wolf J, Kwok Y, Cullen K, Ord R, Zimrin A, Strome S,and
Suntharalingam M. Patterns of failure among patients with squamous cell carcinoma of the head and
neck who obtain a complete response to chemoradiotherapy. Head Neck 2010;32(1):46-52. Epub
2009 May 29.
21. Kwok Y, Yovino S. Radiation-based therapies for prostate cancer. Curr Opin Oncol 2010
May;22(3):257-62.
22. DiBiase SJ, Hussain A, Kataria R, Amin P, Bassi S, Dawson N, and Kwok Y. Long-term results of a
prospective, phase II study of long-term androgen ablation, pelvic radiotherapy, brachytherapy boost
16
Young Kwok, M.D.
23.
24.
25.
26.
27.
28.
29.
and adjuvant docetaxel in patients with high-risk prostate cancer. International Journal of Radiation
Oncology Biology Physics 2011;81(3):732-6. Epub 2010 Oct30.
Hussain A, Wu Y, Mirmiran A, DiBiase S, Goloubeva O, Bridges, Mannuel H, Engstrom C, Dawson
N, Amin P and Kwok Y. Long-term follow-up of a prospective trial of trimodality therapy of weekly
paclitaxel, radiation and androgen deprivation in high risk prostate cancer with or without prior
prostatectomy. International Journal of Radiation Oncology Biology Physics 2012;82(1):167-74.
Epub 2010 Oct 30.
Szerlip N, Rutter C, Ram N, Yovino S, Kwok Y, Maggio W, Regine W. Factors impacting
volumetric white matter changes following whole-brain radiation therapy. Journal of Neuro-Oncology
2011;103(1):111-9. Epub 2010 Aug 20
Koshy M, Rich SE, Mahmood U, Feigenberg S, and Kwok Y. The Declining Utilization of Radiation
Therapy in Stage I and II Hodgkin's Disease and its Impact on Survival and Secondary Malignancies.
In Press. International Journal of Radiation Oncology Biology Physics 2011.
Suntharalingam M, Kwok Y, Goloubeva O, Parekh A, Taylor R, Wolf J, Zimrin A, Strome S, Ord R,
and Cullen K. A Phase II Study Evaluating the Addition of Cetuximab to the Concurrent Delivery of
Weekly Carboplatin, Paclitaxel and Daily Radiotherapy for Patients with Locally Advanced
Squamous Cell Carcinomas of the Head and Neck. International Journal of Radiation Oncology
Biology Physics 2011 May 19. [Epub ahead of print]
Koshy M, Rich S, Merchant E, Mahmood U, Regine W, and Kwok Y. Post-operative Radiation
Improves Survival in Children Younger Than 3 Years with Intracranial Ependymoma. Journal of
Neuro-oncology. 2011;105(3):583-90. Epub 2011 June 3.
Husain ZA, Regine WF, Kwok Y and Feigenberg SJ. Brain Metastases: Contemporary Management
and Future Directions. The European Journal of Clinical & Medical Oncology. June 2011, 3(3). 3845.
Koltz MT, Polifka AJ, Saltos A, Slawson RG, Kwok Y, Aldrich EF, and Simard JM. Long-Term
Outcome of Gamma Knife Stereotactic Radiosurgery for Arteriovenous Malformations Graded by the
Spetzler-Martin Classification. Journal of Neurosurgery 2012;Oct 19. [Epub ahead of print].
30. Diss E, Nalabothula N, Nguyen D, Chang E, Kwok Y, and Carrier F. Vorinostat SAHA
Promotes Hyper-Radiosensitivity in Wild Type p53 Human Glioblastoma Cells. JSM Clin
Oncol Res 2014; 2(1): 1004.
31. Tye K, Engelhard HH, Slavin KV, Nicholas MK, Chmura SJ, Kwok Y, Ho DS, Weichselbaum RR,
Koshy M. An analysis of radiation necrosis of the central nervous system treated with bevacizumab.
J Neurooncol 2014; Feb 7. [Epub ahead of print].
Non-refereed:
1.
Kwok Y, Patchell RA. Commentary on: “The role of radiation in the management of brain
metastases from renal cell carcinoma.” Doh, Amato, Paulino et al. Oncology May 2006;20(6):619625.
Book Chapters:
1.
Kwok Y, Garofalo M, Regine WF. Postoperative Adjuvant Therapy for Pancreatic Cancer. In:
Pancreatic Cancer. Von Hoff DD, Evans DB, and Hruban RH (ch.27, p395-404). Sudbury, MA:
Jones and Barlett, 2005.
2.
Kwok Y, Patchell RA, Regine WF. Palliation of Brain and Spinal Cord Metastases. In: Principles
and Practice of Radiation Oncology (ch.91, p1974-1985). Lippincott Williams & Wilkins; 5th
edition. 2007.
3.
Miker-Zabel S, Kwok Y, Debus J. Skull Base Tumors. In: Principles and Practice of Stereotactic
Radiosurgery (ch.37, p383-392). Springer; 1st edition. 2008
17
Young Kwok, M.D.
4.
5.
6.
7.
Chin LS, Patel S, Mattingly T, Kwok Y. Trigeminal Neuralgia. In: Principles and Practice of
Stereotactic Radiosurgery (ch.52, p519-526). Springer; 1st edition. 2008
Kwok Y, Patchell RA, Regine WF. Management of Overt CNS Metastases: Brain and Spinal Cord.
Lung Cancer: Principles and Practice. Lippincott Williams & Wilkins; 4th edition. April 2010.
Yovino S, Kwok Y, Regine WF. Brain and Cranial Nerves. In: ALERT: Adverse Late Effects of
Cancer Treatment, Volume 2: Specific Normal Tissue Sites. Rubin P, Constine L, Marks L,
Williams J, Hansen J. New York, NY: Springer-Verlag, 2012.
Nichols E, Patchell RA, Regine WF, Kwok Y. Palliation of Brain and Spinal Cord Metastases. In:
Principles and Practice of Radiation Oncology. Lippincott Williams & Wilkins; 6th edition. 2013
Other Brief Communications:
1.
Kwok Y, Regine W, Dibiase SJ. In reply to Dr. Rogers et al. International Journal of Radiation
Oncology Biology Physics 2005 Jun 1;62(2):618-9.
2.
Kwok Y, Patchell RA, Regine W. In reply to Dr. Macbeth et al and Dr. Maranzano et al. Journal of
Clinical Oncology 2005;23(32):8272-8275.
3.
Mahmood U, Kwok Y, Regine WF, and Patchell RA. Whole brain irradiation for patients with
brain metastasis: still the standard of care. Lancet Oncol 2010;11(3):221-2.
Abstracts/Presentations (Selected):
1. Kwok Y, Lanzkowsky P, Karayalcin G. Childhood neutropenias: A fifteen year experience. Poster
Presentation at American Society of Hematology, Miami, Fl, December 1998.
2. Kennedy A, Murthy R, Kwok Y, Kanani S, Tucker G, Desai K, van Echo D. Preliminary results of
outpatient hepatic artery brachytherapy for colorectal hepatic metastases. Oral Presentation at
European Cancer Conference, Lisbon, Portugal, October 2001.
3. Kwok Y, DiBiase S, Amin P, Naslund M, Jacobs S. Risk group stratification in patients undergoing
permanent I-125 prostate brachytherapy as monotherapy. Oral Presentation at Radiological
Society of North America, Chicago, Il, October 2001.
4. Kennedy A, Murthy R, Kwok Y, Tucker G, Kanani S, Desai K, van Echo D. Hepatic artery
brachytherapy for unresectable hepatocellular carcinoma: an outpatient treatment approach. Oral
Presentation at Internation Congress on Anti-Cancer Treatment, Paris, France, February 2002.
5. Kwok Y, Suntharalingam M, Taylor R, Baig F, Yaes R, Mohiuddin M, Regine W. A definitive
evaluation of the impact of treatment related factors on local control in patients with T1 glottic
tumors utilizing Linear-Quadratic Plus Time model. Oral Presentation at Radiological Society of
North America, Chicago, Il, November 2002.
6. Kennedy A, Yovino S, Kwok Y, Duckham E, van Echo D. Long-term follow-up of upper GI
cancers after conformal radiotherapy combined with paclitaxel or capecitabine plus paclitaxel. Oral
Presentation at Radiological Society of North America, Chicago, Il, November 2002.
7. Ronson S, DiBiase S, Kwok Y, Amin P, Naslund M, Jacobs S. Incidence and temporal pattern of
hematuria and proteinuria in men treated with permanent interstitial prostate brachytherapy. Poster
Presentation at American Radium Society, Houston, Tx, April 2003.
8. Kwok Y, DiBiase S, Yovino S, Arena C, Temple R, Regine W, Amin P, Chin L. Improved outcome
with adequate dural tail coverage in patients with intracranial meningiomas treated with Gamma
Knife stereotactic radiosurgery. Poster Discussion at American Society of Therapeutic Radiology
and Oncology, Salt Lake City, Ut, October 2003
9. Kennedy A, Kwok Y, Batko-Yovino S, van Echo D. A phase I study of preoperative capecitabine,
irinotecan concurrent with radiation therapy for resectable rectal cancer. Poster Presentation.
American Society of Clinical Oncology GI Symposium, San Francisco, Ca, January 2003.
10. Yovino S, BA, Kwok Y, Krasna M, Bangalore M, Suntha M. Preoperative Anemia Decreases
Survival in Patients with Stage I and II Non-Small-Cell Lung Cancer Treated with Surgery. Poster
Presentation at American Society of Therapeutic Radiology and Oncology, Atlanta, Ga, October
2004.
18
Young Kwok, M.D.
11. Kwok Y, Murali N, Chin L, Bangalore M, Amin P, and Regine W. Long-term Results of Gamma
Knife Stereotactic Radiosurgery for Non-functioning Pituitary Adenomas. Poster Presentation at
American Society of Therapeutic Radiology and Oncology, Atlanta, Ga, October 2004.
12. Dutta, P.R., Kwok Y, Chin, L.S., Herman, J.M., Colliver, C., St. Clair, W., Petit, J., Young, B., and
Regine, W.F. Comparison of Repeat GK-SRS for Refractory or Recurrent Trigeminal Neuralgia:
Does Dose Matter? Poster Presentation at American Society of Therapeutic Radiology and
Oncology, Atlanta, Ga, October 2004.
13. Sullivan P, Ord R, Gray W, Wolf J, Taylor R, VanEcho D, Kwok Y, Suntharalingam M. Long-term
survival and functional quality of life assessments in patients with locally advanced unresectable
squamous cell carcinomas of the head and neck treated with concurrent chemoradiation. Poster
Presentation at American Society of Therapeutic Radiology and Oncology, Atlanta, Ga, October
2004.
14. Patel S, Kwok Y, Shepard D, Chin L, Slawson R, Amin P, and Regine W. Evaluating the influence
of dose-rate on outcome with gamma-knife stereotactic radiosurgery in the treatment of trigeminal
neuralgia. Poster Presentation at American Society of Therapeutic Radiology and Oncology,
Denver, Co, October 2005.
15. SJ DiBiase, N Dawson, Y Kwok, R Kataria, A Hussain, S Nagda, M Bangalore, P Amin. Phase II
Trial of External Radiotherapy, Brachytherapy, Androgen Deprivation, and Docetaxel
Chemotherapy for High-Risk, Localized Prostate Cancer. Poster Presentation at American Society
of Therapeutic Radiology and Oncology, Denver, Co, October 2005.
16. Dhople A, Kwok Y, Jaboin J, Chin L, Slawson R, Amin P and Regine W. Evaluation of Efficacy
and Quality of Life in Patients with Atypical Facial Pain Treated with Gamma-Knife Stereotactic
Radiosurgery. Oral Presentation at American Society of Therapeutic Radiology and Oncology,
Denver, Co, October 2005.
17. Flannery T, Kwok Y, Naslund M, and Amin P. Long-term Results of Intermediate and High-Risk
Prostate Cancer Patients Treated with Prostate Brachytherapy. Poster Presentation (Resident Travel
Grant for Todd Flannery, M.D.) at American Brachytherapy Society, Philadelphia, PA, May 2006.
18. Flannery T, Kwok Y, Krasna L, Chin L, Shehata M, Kremer M, Jaboin J, Suntha M, Regine W. The
Impact of Definitive Thoracic Management on Long-Term Survival in Patients with Synchronous,
Solitary Brain Metastases from Non-Small Cell Lung Cancer Treated with Stereotactic
Radiosurgery. Oral Presentation at American Society of Therapeutic Radiology and Oncology,
Philadelphia, Pa, November 2006.
19. Thomas O, Kwok Y, Dhople A, Chin L, Slawson, Regine W, Long-term outcome of patients treated
with Gamma Knife stereotactic radiosurgery for brain metastases secondary to malignant melanoma
or renal cell carcinoma. Poster Presentation at Radiological Society of North America, Chicago, Il,
November 2006
20. Settle K, Taylor R, Wolf J, Kwok Y, Cullen K, Carter K, Ord R, Zimrin A, Strome S and
Suntharalingam M. Race Impacts Outcome in Stage III/IV Squamous Cell Carcinomas of the Head
and Neck Following Concurrent Chemoradiation Therapy. Poster Discussion at American Society
of Therapeutic Radiology and Oncology, Los Angeles, November 2007.
21. Kwok Y, Won M, Regine WF, Mehta M, Schmitt F, Patchell RA, and Watkins-Bruner D.
Neurocognitive Impact of Whole Brain Radiation on Patients With Brain Metastases: Secondary
Analysis of RTOG BR-0018. Oral Presentation at American Society of Therapeutic Radiology and
Oncology, Los Angeles, November 2007.
22. Adams JR, Dhople AA, Kwok Y, Yu XU, Simard JM, Maggio W and Regine. Long Term Followup of Gamma Knife Stereotactic Radiosurgery for Trigeminal Neuralgia. Oral Presentation at
American Society of Therapeutic Radiology and Oncology, Los Angeles, November 2007.
23. Dhople AA, Adams JR, Kwok Y, Yu XU, Simard JM, Maggio W and Regine WF. Long Term
Follow-up of Repeat Gamma Knife Stereotactic Radiosurgery for Refractory or Recurrent
Trigeminal Neuralgia. Oral Presentation at American Society of Therapeutic Radiology and
Oncology, Los Angeles, November 2007.
19
Young Kwok, M.D.
24. Carter K, Settle K, Taylor R, Wolf J, Kwok Y, Cullen K, Ord R, Zimrin A, Strome S and
Suntharalingam. Site as a Prognostic Factor in Patients with Stage III/IV Squamous Cell Carcinoma
of the Head and Neck Following Definitive Chemoradiation. Poster Presentation at American
Society of Therapeutic Radiology and Oncology, Los Angeles, November 2007.
25. Yovino S, Settle K, Taylor R, Wolf J, Kwok Y, Cullen K, Ord R, Zimrin A, Strome s and
Suntharalingam M. Can Adjuvant Neck Dissection be Deferred in Locally Advanced Head and Neck
Cancer Patients With Complete Response to Definitive Chemoradiotherapy? Oral Presentation at
American Society of Therapeutic Radiology and Oncology, Los Angeles, November 2007.
26. Patel AB, Edelman M, Burrows W, Hausner P, Kwok Y, Krasna M and Suntharalingam M. The
Impact of Prophylactic Cranial Irradiation in Patients with Locally Advanced Non-Small Cell Lung
Cancer Treated With Trimodality Therapy. Poster Discussion at American Society of Therapeutic
Radiology and Oncology, Los Angeles, November 2007.
27. Kwok Y, Kataria R, Amin P, Naslund M, Hussain A, Dawson N, and Dibiase S. Long-term Results
of a Prospective Phase II Trial of Androgen Ablation, Pelvic External Beam Radiation Therapy,
Brachytherapy Boost, and Adjuvant Docetaxel in High-risk Prostate Cancer. Oral Presentation at
American Society of Therapeutic Radiology and Oncology, Boston, Ma, September 2008.
28. Mahmood U, Richards L, D'Souza W, Naslund M, Amin P and Kwok Y. Dosimetric Analysis of the
Effect of Prostate Edema on Cs-131 Brachytherapy. Poster Presentation at American Society of
Therapeutic Radiology and Oncology, Boston, Ma, September 2008.
29. Yovino SB, Rutter C, Szerlip N, Kwok Y, Maggio W and Regine WF. Long-term Survivors of
Brain Metastases (BM) Have Optimal Brain Tumor Control with Combined Whole Brain Radiation
(WBRT) and Stereotactic Radiosurgery (SRS). Poster Presentation at American Society of
Therapeutic Radiology and Oncology, Chicago, Il, Noveber 2009.
30. Koshy M, Rich S, Merchant T, Regine W and Kwok Y. Postoperative Radiation Improves Overall
Survival in Children Age <3 Years with Intracranial Ependymoma. Poster Presentation at American
Society of Therapeutic Radiology and Oncology, Chicago, Il, November 2009.
31. Diwanji T, Dhople A, Chin L, Maggio W, Adams J, Regine W and Kwok Y. Long-term Outcome
of Gamma Knife Stereotactic Radiosurgery for Multiple Sclerosis Associated Trigeminal Neuralgia.
Poster Presentation at American Society of Therapeutic Radiology and Oncology, San Diego, Ca,
November 2010.
32. Kwok Y, Wu Y, Mirmiran A, DiBiase S, Goloubeva O, Bridges B, Mannuel H, Dawson N, Amin P
and Hussain A. Prospective Trial of Escalating Doses of Paclitaxel, Concurrent Radiation and
Androgen Deprivation in High Risk Prostate Cancer With or Without Prior Prostatectomy. Longterm Outcome of Gamma Knife Stereotactic Radiosurgery for Multiple Sclerosis Associated
Trigeminal Neuralgia. Poster Presentation at American Society of Therapeutic Radiology and
Oncology, San Diego, Ca, November 2010.
33. Regine W, Szerlip N, Rutter C, Ram N, Yovino S, Maggio W and Kwok Y. Factors Impacting
White Matter Changes Following Whole Brain Radiation Therapy. Poster Presentation at American
Society of Therapeutic Radiology and Oncology, San Diego, Ca, November 2010.
34. Saltos A, Koltz M, Aquino C, Obuchowski A, Kim G, Kwok Y, and Simard J. Staged-dose
radiosurgical outcomes for symptomatic and asymptomatic intracranial arteriovenous
malformations. Poster Presentation at American Society of Therapeutic Radiology and Oncology,
Miami, Fla, October 2011.
35. Carrier F, Diss E, Nalabothula N, and Kwok Y. The histone deacetylase inhibitor vorinostat induces
hyper-radiosensivity in P53 wild type glioblastoma cells. Poster Presentation at American Society of
Therapeutic Radiology and Oncology, Miami, Fla, October 2011.
36. Kwok Y, Saltos A, Boggs D, Naslund M, Hussain A, and Amin P. Long-term follow-up of
combined modality therapy with pelvic external radiation followed by Cs-131 brachytherapy boost
in men with high-risk prostate cancer. Poster Presentation at American Society of Therapeutic
Radiology and Oncology, Boston, Ma, October 2012.
20
Young Kwok, M.D.
37. Kwok Y, Ferris M, Moshe M, Kataria R, Nickerson C. Interim Results of a Prospective Phase II
Trial of Pelvic IMRT, Cesium-131 Brachytherapy Boost, Adjuvant Docetaxel Chemotherapy, and
Long Term Androgen Ablation for Patients with High Risk Prostate Cancer. Oral Presentation at
American Society for Radiation Oncology, Atlanta, Ga 2013.
Proffered Communications:
1. Kwok Y, M Won, WF Regine, M Mehta, F Schmitt, RA Patchell, and D Watkins-Bruner.
Neurocognitive Impact of Whole Brain Radiation on Patients with Brain Metastases: Secondary
Analysis of RTOG BR-0018. Oral Presentation at Radiation Therapy and Oncology Group, San
Diego, Ca, January 19, 2008.
Invited Speeches
1.
February 12, 2002
2.
November 5, 2003
3.
December 10, 2003
4.
January 21, 2004
5.
March 9, 2004
6.
June 15, 2004
7.
June 19, 2004
8.
June 19, 2004
9.
October 15, 2004
10.
October 15, 2004
11.
November 15, 2004
12.
November 15, 2004
13.
May 26, 2005
14.
July 7, 2005
15.
November 12, 2005
16.
December 3, 2005
Contemporary Management of Supratentorial High-Grade Gliomas.
Grand Rounds. Greenebaum Cancer Center, Univ of Maryland Medical
Center, Baltimore, MD.
Introduction to Radiation Oncology. Greenebaum Cancer
Center, Univ of Maryland Medical Center, Baltimore, MD.
Gamma Knife Stereotactic Radiosurgery for Trigeminal Neuralgia:
University of Maryland Experience. Univ of Maryland Medical CenterCME Lecture. Baltimore, MD.
Gamma Knife Stereotactic Radiosurgery for Trigeminal Neuralgia:
University of Maryland Experience. CME Lecture. Bethesda, MD.
Gamma Knife Stereotactic Radiosurgery for Trigeminal Neuralgia:
University of Maryland Experience. CME Lecture. Annapolis, MD.
Contemporary Management of Central Nervous and Head and Neck
Tumors. Greenebaum Cancer Center, Univ of Maryland Medical Center,
Baltimore, MD.
Diagnosis and Treatment of Trigeminal Neuralgia. Greater Baltimore
Medical Center, Baltimore, MD.
Gamma Knife Stereotactic Radiosurgery for Trigeminal Neuralgia:
University of Maryland Experience. Greater Baltimore Medical Center,
Baltimore, MD.
Diagnosis and Treatment of Trigeminal Neuralgia. Cambridge Dental
Group, Cambridge, MD.
Gamma Knife Stereotactic Radiosurgery for Trigeminal Neuralgia:
University of Maryland Experience. Cambridge Dental Group,
Cambridge, MD.
Diagnosis and Treatment of Trigeminal Neuralgia. Holy Cross
Hospital, Silver Spring, MD.
Gamma Knife Stereotactic Radiosurgery for Trigeminal Neuralgia:
University of Maryland Experience. Holy Cross Hospital, Silver Spring,
MD.
The Role of Radiotherapy in Genito-urinary Malignancies. Grand
Rounds. Division of Urology, UMSOM, Baltimore, MD.
Introduction to Radiation Oncology. National Youth Leadership
Forum. University of Maryland Medical Center, Baltimore, MD
Lymphoma Review. Annual Mid-Atlantic American Society of
Therapeutic Radiology Oncology Review. UMSOM, Baltimore, MD
Management of Brain Metastasis from Lung Cancer. UMSOM Annual
Thoracic Malignancy Update, Cambridge, MD
21
Young Kwok, M.D.
17.
October 12, 2006
18.
December 7, 2006
19.
December 15, 2006
20.
March 23, 2007
21.
April 13, 2007
22.
June 2, 2007
23.
October 25, 2007
24.
December 13, 2007
25.
January 10, 2008
26.
March 6, 2008
27.
March 26, 2008
28.
October 6, 2008
29.
October 23, 2008
30.
January 8, 2009
31.
February 27, 2009
32.
October 8, 2009
33.
November 11, 2009
34.
December 2, 2009
35.
February 18, 2010
36.
April 22, 2010
37.
October 18, 2010
38.
January 6, 2011
Management of Spinal Cord Compression. European Society of
Therapeutic Radiology and Oncology, Leipzig, Germany
CNS Review. Annual Mid-Atlantic American Society of Therapeutic
Radiology Oncology Review. UMSOM, Baltimore, MD
Stage I and II Seminoma. Solid-Tumor Board. University of Maryland
Medical Center, Baltimore, MD
Prostate Cancer: Treatment Overview. Solid-Tumor Board. University
of Maryland Medical Center, Baltimore, MD
Prostate Cancer: Determinants of Outcome. Solid-Tumor Board.
University of Maryland Medical Center, Baltimore, MD
Whole Brain Radiation Therapy in the Management of Brain
Metastasis from Non-small Cell Lung Cancer. American Society of
Clinical Oncology, Chicago, Il
CNS Malignancies. Greenebaum Cancer Center, Univ of Maryland
Medical Center, Baltimore, MD.
Prostate Cancer: Treatment Overview. Greenebaum Cancer Center,
Univ of Maryland Medical Center, Baltimore, MD
Genito-urinary Review. Annual Mid-Atlantic American Society of
Therapeutic Radiology Oncology Review. UMSOM, Baltimore,
MD
Chemoradiation in Locally-Advanced Cervical Cancer. Greenebaum
Cancer Center, Univ of Maryland Medical Center, Baltimore, MD
Recent Technological Advances in Radiation Oncology. FDA: Center
for Devices and Radiological Health—The Federal Research Center @
White Oak, Silver Springs, MD
Contemporary Management of Non-metastatic Prostate Cancer. Grand
Rounds. Greenebaum Cancer Center, Univ of Maryland Medical Center,
Baltimore, MD
Contemporary Management of Non-metastatic Prostate Cancer. Grand
Rounds. Division of Urology, UMSOM, Baltimore, MD
CNS Review. Annual Mid-Atlantic American Society of Therapeutic
Radiology Oncology Review. UMSOM, Baltimore, MD
Introduction to Radiation Oncology. University of Maryland Radiation
Oncology Interest Group. Univ of Maryland School of Medicine,
Baltimore, MD
High-Risk Prostate Cancer: Are We There Yet? Grand Rounds.
Laurel Regional Hospital, Laurel, MD.
Prostate: Technological Advances. UMMC Consumer Seminar Series
Pikesville Hilton, Pikesville, MD.
Introduction to Radiation Oncology. University of Maryland Radiation
Oncology Interest Group. Univ of Maryland School of Medicine,
Baltimore, MD
Recent Technological Advances in Radiation Oncology. Grand Rounds.
Children’s National Medical Center. Washington, DC.
Recent Advances in Radiation Oncology for GU Cancers. Grand
Rounds. Upper Chesapeake Medical Center, Bel Air, MD.
Contemporary Management of Muscle-Invasive Bladder Cancer. Grand
Rounds. Greenebaum Cancer Center, Univ of Maryland Medical Center,
Baltimore, MD
GU Review. Annual Mid-Atlantic American Society of Therapeutic
Radiology Oncology Review. UMSOM, Baltimore, MD
22
Young Kwok, M.D.
39.
March 3, 2011
40.
October 13, 2011
41.
March 8, 2012
41.
May 30, 2012
42.
September 13, 2012
43. January 24, 2013
44.
October 24, 2013
45. January 9, 2014
Role of Radiation Therapy in Pituitary Adenomas. Endocrinology
Fellows Lecture. Division of Endocrinology, Univ of Maryland Medical
Center, Baltimore, MD
Trigeminal Neuralgia. Grand Rounds. Dept of Neurosurgery, Univ of
Maryland Medical Center, Baltimore, MD
Post-Prostatectomy Radiation. Grand Rounds. Division of Urology,
Univ of Maryland Medical Center, Baltimore, MD
PSA Screening Controversy. Grand Rounds. Internal Medicine. Harbor
Hospital, Baltimore, MD
Role of Brachytherapy in High-Risk Prostate Cancer. Visiting Professor.
Grand Rounds. Georgetown University. Washington, DC.
Extent of Resection in Brain Tumors. Grand Rounds. Dept of
Neurosurgery, Univ of Maryland Medical Center, Baltimore, MD
PSA Screening Controversy. Grand Rounds. Internal Medicine. Laurel
Regional Hospital, Baltimore, MD
GU Review. Annual Mid-Atlantic American Society of Therapeutic
Radiology Oncology Review. UMSOM, Baltimore, MD
23