STATE EXAM QUESTIONS – 6th YEAR I. A1 A2 A3 A4 A5 A6 A7 A8 A9 A10 A11 A12 A13 A14 A15 A16 A17 A18 A19 A20 A21 A22 A23 A24 A25 A26 A27 Chest pain - differential diagnosis. Dyspnoe - differential diagnosis. Edema - differential diagnosis. Unconsciousness (syncopes, coma) - cause, differential diagnosis, therapy. Cardiac arrest. Principles of cardiopulmocerebral resuscitation. Diagnostic methods in cardiology. Acute heart failure - pathogenesis, symptoms, therapy. Chronic cardiac insufficiency - pathogenesis, symptoms, diagnostic methods, treatment. Treatment of chronic heart failure. Arrythmias (abnormalities of automacity and conduction) - classification, clinical features, diagnostic methods, therapy. Chronic ischemic heart disease. Acute coronary syndrome. Myocardial infarction. Inflammatory heart diseases (endocarditis, myocarditis, pericarditis). Cardiomyopathies - classification, clinical features, differential diagnosis, therapy. Mitral valve diseases - etiopathogenesis, clinical features, diagnosis, therapy. Aortic valve diseases - etiopathogenesis, clinical features, diagnosis, therapy. Arterial hypertension - epidemiology, etiopathogenesis, classification, clinical features, diagnosis. Therapy of arterial hypertension. Secondary hypertension - epidemiology, etiopathogenesis, clinical features, therapy. Hypertensive crisis - causes, clinical features, treatment. Peripheral arterial disease of lower extremities. Thrombophlebitis, insufficiency of the leg veins. Venous thromboembolism, thrombophilic states. Shock - pathogenesis, classification, differential diagnosis, symptoms, therapy. Vasoneurosis - classification, clinical features, diagnostic methods, therapy. Primary and secondary prevention of cardiovascular diseases. II. B1 Cough - etiology, differential diagnosis. B2 Hemoptoe - etiology, differential diagnosis, treatment. B3 Lower respiratory tract acute inflammations - etiology, pathogenesis, classification, clinical manifestation, treatment. B4 Chronic obstructive pulmonary disease - etiopathogenesis, clinical manifestation, treatment. B5 Bronchial asthma - etiopathogenesis, clinical manifestation, diagnosis, differential diagnosis, treatment. B6 Pneumonia, bronchopneumonia - classification, clinical manifestation, diagnosis, differential diagnosis, treatment, complications. B7 Sarcoidosis of the lower respiratory tract - etiopathogenesis, clinical manifestation, diagnosis, treatment. B8 Idiopathic interstitial pneumonia – classification, clinical manifestation, diagnosis, differential diagnosis, treatment. B9 Chronic respiratory failure - causes, clinical manifestation, treatment. B10 Pleural effusion - etiology, differential diagnosis, management. B11 Pneumothorax, pleural tumors. B12 Diseases of mediastinum (tumors, inflammatory processes) - differential diagnosis. B13 Epidemiology and pathogenesis of tuberculosis. B14 Clinical manifestation and X-ray features of tuberculosis, diagnosis and differential diagnosis. B15 Treatment of tuberculosis. B16 Bronchogenic carcinoma - etiopathogenesis, classification, clinical manifestation, diagnosis, differential diagnosis, treatment. B17 Sleep-related breathing disorders - clinical manifestation, diagnosis, treatment. B18 Pneumoconiosis (Silicosis, coal worker pneumoconiosis, asbestosis). B19 Professional allergic respiratory diseases (Extrinsic allergic alveolitis, occupational bronchial asthma). _______________________ III. C1 Abdominal pain/ differential diagnosis. C2 General symptoms of diseases of the upper gastrointestinal tract. C3 General symptoms of diseases of the lower gastrointestinal tract. C4 Gastrointestinal bleeding - causes, differential diagnosis. C5 Diagnostic methods in gastroenterology. C6 Diseases of esophagus and inflammatory diseases of stomach. C7 Peptic ulcer disease of stomach and duodenum.. C8 Esophageal and stomach tumors. C9 Malabsorption syndrome, celiac disease. C10 Non - specific inflammatory bowel diseases. C11 Functional disorders of gastrointestinal tract. C12 Tumors of the colon and rectum. C13 Jaundice - classification, differential diagnosis. C14 Hepatomegaly and splenomegaly – etiopathogenesis, differential diagnosis. C15 Portal hypertension. Ascites - etiopathogenesis, differential diagnosis, treatment. C16 Hepatic coma - pathophysiology, clinical manifestation, therapy. C17 Acute and chronic hepatitis. Toxic damage of the liver. C18 Cirrhosis of the liver. C19 Diseases of gallbladder and biliary tract. C20 Hepatic and biliary tumors. C21 Tumors of pancreas. C22 Acute pancreatitis. C23 Chronic pancreatitis. IV. D1 Functional and morphological examinations of the kidney. D2 Proteinuria, hematuria, leucocyturia - differential diagnosis. D3 Acute and chronic renal insufficiency. D4 Acute and chronic glomerulonephritis. D5 Tubulointerstitial nephritis. D6 Nephrotic syndrome. D7 Tumors of kidney and urinary tract. D8 Disorders of water metabolism. D9 Disorders of mineral metabolism. D10 Disorders of acid-base balance (acidosis, alkalosis). D11 Poisoning - definition, classification, basics of diagnosis and therapy. D12 Poisoning by medicaments (analgesics, hypnotic drugs, depressants, addictive drugs). D13 Poisoning by ethylalcohol, methylalcohol and ethyleneglycol. D14 Poisoning by mushrooms. D15 Poisoning by pesticides (organophosphates, carbamates). D16 Poisoning by organic solvents (benzene and its homologues, chlorinated hydrocarbons). D17 Poisoning by carbon monoxide, hydrogen cyanide, potassium and sodium cyanide. D18 Poisoning due to metals - lead (Pb), mercury (Hg), chromium (Cr), arsenic (As). D19 Injury of organism by ionizing and electromagnetic radiation. D20 Professional diseases, definition, most frequent professional diseases in health service, machine industry and mining. __________________________________________ V. E1 Diabetes mellitus - epidemiology, etiopathogenesis, classification, clinical manifestations, diagnosis. E2 Diabetes mellitus - therapy, prevention. E3 Acute and chronic complications of diabetes mellitus. E4 Dyslipidemia. E5 Obesity. Metabolic syndrome. E6 Gout and hyperuricemic syndrome. E7 Disorders of nutrition (undernutrition, cachexia). Principles of parenteral and enteral nutrition. E8 Porphyrias. E9 Disorders of hypothalamus and hypophysis. E10 Thyreotoxicosis. E11 Hypothyroidism. E12 Inflammatory and neoplastic diseases of thyroid gland. E13 Diseases of parathyroid glands. Disorders of calcium metabolism. E14 Disorders of adrenal glands. E15 Osteoporosis. E16 Glucocorticoids - indications, contraindications, adverse effects and their prevention. VI. F1 Anemia - diagnostic approach and therapy. F2 Aplastic anemia. Myelodysplastic syndrome. F3 Myeloproliferative syndromes. F4 F5 F6 F7 F8 Acute leukemias. Lymphoproliferative disorders - Malignant lymphomas. Multiple myeloma. Hemorrhagic - bleeding disorders. Principles of antithrombotic (fibrinolytic, anticoagulant and antiplatelet) treatment. Blood transfusion - indications, contraindications, technique. Posttransfusion reactions. F9 Lymph node diseases - cause, differential diagnosis. F10 Arthralgia - differential diagnosis of degenerative and inflammatory joint diseases. F11 Joint diseases associated with infection (reactive arthropathies, rheumatic fever). F12 Systemic diseases of connective tissue - Rheumatoid arthritis. F13 Sepsis. F14 Fever - classification, differential diagnosis. F15 Antibiotics - classification, indications, contraindications. F16 Non-specific and specific symptoms of malignant tumors. F17 Human immunodeficiency virus infection. F18 Primary and secondary amyloidosis.