3.7 Empirical Bayes Analysis Motivation: For X i i i , i ~ N 0, 2 , i 1,2,, p. Then, the MLE estimate is ˆi X i (higher dimensional model). If 1 2 p , the MLE estimate is p ˆ X X i 1 i (lower dimensional model). p Question to ask: which model is better (lower or higher)? Answer: empirical Bayes analysis is particular desirable in this situation. Empirical “compromise” Bayes between the method model provides where i a are completely unrelated (higher dimensional model) and that where all the i are assume to be equal (lower dimensional model). (a) Introduction There are two types of empirical Bayes methods. One is parametric empirical Bayes (PEB) and the other is nonparametric empirical Bayes (NPEB). 1 Parametric empirical Bayes: the prior is in some parametric class with unknown hyperparameters. Nonparametric empirical Bayes: one typically assume only that i are i.i.d. from some prior . Example 20: Let X i ~ N i , 2 , i ~ N , 2 , where and 2 are unknown hyperparameters. ◆ Two different ways to carry out empirical Bayes analysis are 1. estimating the prior or posterior by data first, then use or ˆ | x ˆ to carry out the standard Bayes analysis. 2. finding the Bayes rule in term of unknown prior, and use the data to estimate the Bayes rule. (b) Parametric empirical Bayes for normal mean Example 15 (continue): X1, X 2 ,, X p , X i ~ N i ,1, ~ N , 2 Then, 1. m xi ~ N ,1 2 The prior using ML-II method is . ˆ ~ N ˆ ,ˆ2 N x , max 0, s 2 1 , 2 where ̂ x ˆ 2 max 0, s 2 1. and 2. The posterior distribution for X i is 2 xi 2 f i | xi ~ N , 2 2 . 1 1 Then, the parameter estimate using Bayes rule under square-loss function is the posterior mean 2 xi 1 2 xi xi ˆ i 1 2 1 2 x i xi 1 2 xi B xi 1 B xi B where B 1 . Further, the posterior variance is 1 2 2 Vˆi 1 B . 1 2 Note: B 0 ˆi xi ˆ B 1 i ◆ Morris (1983, JASA) suggested p 3 1 ˆ B p 1 1 ˆ 2 , and then the empirical Bayes estimate is ˆ x B ˆ ˆ 1 B ˆ x B ˆx ˆiEB 1 B i i ˆ 2B ˆ 2 x x 2 p 1B EB i ˆ Vi 1 p p3 3 , where ̂ and ˆ 2 . are the estimates obtained in step 1. The estimated posterior distribution is fˆ i | x ~ N ˆiEB ,Vˆi EB Note: B 0 ˆi xi ˆ B 1 i The 1001 % HPD credible set for i is CiEB ˆiEB z1 Vˆi EB ,ˆiEB z1 Vˆi EB 2 2 and The 1001 % HPD credible set for is C EB p i ˆiEB : Vˆi EB i 1 2 2 p ,1 . Example 21: Y1 , Y2 ,, Yn , Yi ~ N i ,1, i xi 1 xi1 2 xi 2 p xip i , i ~ N 0, 2 xi xi1 Then, 1. Since xi 2 xip , 1 2 i ~ N xi , 2 m yi ~ N xi ,1 2 The marginal distribution is then 4 . p t m y m y1 , y2 ,, yn 2 1 2 2 1 2 n 2 n 2 n y i x i 2 i 1 e 2 1 2 e y x t 1 y x 2 where x11 x12 y1 x y x22 21 2 y , X xn1 xn 2 yn ̂ and ˆ 2 minimizing x1 p 1 2 0 x2 p 0 1 2 , xnp 0 0 0 0 1 2 m x also minimize y X t 1 y X . Thus, ˆ X t ˆ 1 X n 1 ˆ 1 y X t y x ˆ i i 2 i 1 ˆ n 2 1 where 1 ˆ 2 0 1 ˆ 2 ˆ 0 0 0 Since ̂ involves ˆ 2 and ˆ 2 0 0 . 1 ˆ 2 involves scheme to solve. 2. The posterior distribution for Yi is 5 ̂ , we have to use iterative 2 yi xi 2 f i | yi ~ N , 2 2 . 1 1 Similar to the previous example, the Empirical Bayes estimates are ˆiEB yi Cˆ i yi xi ˆ ˆ Cˆ ˆ2 n l 2 C EB i i i ˆ Vi 1 yi xi ˆ ˆ n n li 2 where n lˆi 2 1 ˆ Ci 1 ˆ2 n lˆi and ˆ 1 X nX X ˆ li 1 ˆ 2 t 1 , Xt (c) Non-parametric empirical Bayes analysis Example 22: X 1 , X 2 ,, X p , X i ~ P i , i are i.i.d. from a common prior 0 Under square loss, the estimate is the posterior mean, 6 ii 2 xi E f | x i i i i f i | xi d i i f xi | i 0 i d i m 0 xi 1 m 0 xi i ix e i 0 i d i i xi ! x 1 ix 1e 0 i d i m xi xi 1! x 1m xi 1 f xi 1 | i m xi 1 0 i d i m xi x 1m xi 1 f i | xi 1d i m xi x 1m xi 1 m xi i i 0 0 0 0 0 0 0 0 Further, we can estimate the marginal distribution by the empirical distribution p ˆ 0 x m I x i 1 x p i , 1 as xi x I x where x i . Thus, the empirical Bayes estimate for 0 as xi x i is 7 ˆ EB x xi 1 I xi 1 x j p j 1 I xi x j p j 1 8 .