CURRICULUM VITAE - GEORGE PETRIKKOS Name: George Petrikkos Address: 1 Rimini Street, 124 62, Athens, Greece Tel: +30 210-5831989 Fax: +30 210-5326426 E-mail: petrikos@hol.gr Graduate Studies 1966-1973: National and Kapodistrian University of Athens School of Medicine (M.D.) Postgraduate Studies 1974-1977: Intern and Resident in Internal Medicine, “Laikon” General Hospital, Athens, Greece 1978-1980: Scientific collaborator and research fellow, Infectious Diseases and Antimicrobial Chemotherapy Research Lab “GK DAIKOS”, 1st Dept Propaedeutic Medicine , National and Kapodistrian University of Athens Medical School, Athens, Greece 1979: PhD Thesis, National and Kapodistrian University of Athens Medical School, Athens Greece 1979: Specialty National Boards in Internal Medicine 1985: Research fellow, St. Thomas’ Hospital Medical School, United Medical and Dental Schools of Guy`s and St. Thomas’ Hospitals (University of London) 1986: Infectious diseases training, Ιnstitut Jules Bordet , Universite Libre De Bruxelles 1990: Training in molecular mechanism of resistance - Schering-Plough, New Jersey, USA 1999: Subspecialty in Infectious Diseases. Appointments 1978-1979: Internal Medicine specialist in “Laikon” General Hospital ICU 1980-1982: Attending physician, “Laikon” General Hospital 1982-1984: Instructor in Internal Medicine, “Laikon” General Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece 1986-1989: Lecturer in Internal Medicine and Infectious Diseases, “Laikon” General Hospital, University of Athens Medical School, Athens, Greece 1989-2001: Assistant professor in Internal Medicine and Infectious Diseases, “Laikon” General Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece 1999-2009: Head of the Infectious Diseases and Antimicrobial Chemotherapy Research Lab “GK DAIKOS”, 1st Dept Propaedeutic Medicine , National and Kapodistrian University of Athens Medical School. 2001-2008: Associate Professor in Internal Medicine and Infectious Diseases, “Laikon” General Hospital, National and Kapodistrian University of Athens, Athens, Greece 2008-2009: Professor in Internal Medicine and Infectious Diseases, “Laikon” General Hospital, National and Kapodistrian University of Athens, Athens, Greece 2009- Present: Head of the 4th Dept Internal Medicine “ATTIKON’’ University Hospital, Athens , Greece 2010-Present: Medical Director of ‘’ATTIKON’’ University Hospital, Athens, Greece. Research interests Dr Petrikkos clinical and research interests include: in vitro testing of the susceptibilities of nosocomial and community-acquired bacteria to new antimicrobial agents; in vivo controlled clinical trials on the efficacy and pharmacokinetics of newer antimicrobials; nephrotoxicity studies of antibiotics; neutropenic host studies; fungal infections and antifungal agents; infectious diseases and resistance surveillance studies; investigation of underlying resistance mechanism in microorganisms and surveillance studies on antibiotic policies in Greek hospitals. Memberships President of the Mediterranean Society of Chemotherapy (MSC), the Cyprus Society of Chemotherapy and Infectious Diseases Past president of the Hellenic Society of Medical Mycology , and the Hellenic Society of Lymphology. Past Secretary General of the European Confederation of Medical Mycology (ECMM). and the Hellenic Society of Chemotherapy Member of the executive committee of the International Society of Chemotherapy ,the Federation of European Societies of Chemotherapy and Infection (FESCI), the European Society of Chemotherapy and the Hellenic Society of Infectious Diseases. Coordinator of the ECMM/ISHAM Working Group on Zygomycosis and the ISC Working Group on Fungal Infections . Coordinator of the Working group of the Hellenic Society of Chemotherapy of the Febrile Neutropenia. Coordinator for the syntax guidelines for the Zygomycosis. Member of the European Organisation for Research and Treatment of Cancer—Infectious Diseases Group (EORTC-IDG), the European Conference on Infection in Leukemia and the EFISG of ESCMID. As a strong believer in evidence-base medicine Professor Petrikkos participated in tree European guideline groups (ECIL ,ECMM/ISHAM, and EFISG – ESCMID) that have produced guidelines on the diagnosis and treatment of infections in Leukemia patients, Zygomycosis – Mucormycosis and Candidiasis National (Cyprus) representative of European Union of Medical Specialist, section Infectious Diseases (UEMM).. Reviewer of 15 medical Journals and 12 congreses.. Dr. Petrikkos is the author of over 250 publications in Greek and international scientific journals Recent Publications (Last 5 years) 1. Daikos GL, Kosmidis C, Tassios PT, Petrikkos G, Vasilakopoulou A, Psychogiou M, Stefanou I, Avlami A, Katsilambros N. Enterobacteriaceae bloodstream infections: presence of integrons, risk factors, and outcome. Antimicrob Agents Chemother. 2007 Jul;51(7):2366-72. 2. Petrikkos G, Makrilakis K, Pappas S. Affirm VP III in the detection and identification of Candida species in vaginitis. Int J Gynaecol Obstet. 2007 Jan;96(1):39-40. 3. Petrikkos G, Markogiannakis A, Papaparaskevas J, Daikos GL, Stefanakos G, Zissis NP, Avlamis A. Differences in the changes in resistance patterns to third-and fourth-generation cephalosporins and piperacillin/tazobactam among Klebsiella pneumoniae and Escherichia coli clinical isolates following a restriction policy in a Greek tertiary care hospital. Int J Antimicrob Agents. 2007 Jan;29(1):34-8. 4. G.Petrikkos,A.Skiada. Recent advances in antifungal chemotherapy.Int J Antimicrob Agents 2007;30:108-17. 5. Petrikkos GL, Hadjisoteriou M, Daikos GL. PCR versus culture in the detection of vaginal Ureaplasma urealyticum and Mycoplasma hominis. Int J Gynaecol Obstet. 2007 Jun;97(3):202-3. Epub 2007 Mar 21. PubMed PMID: 17368648. 6.Epidemiological and Clinical investigation of Gram-negative anaerobic infections in Greece. A.Katsandri,A.Avlamis,NJ Legakis,G.L.Petrikkos,A.Pantazatou,J.Papaparaskevas.International Journal of Antimicrobial Agents 2007;29:379-379. 7. Pappas S, Makrilakis K, Anyfantis I, Mitroussia-Ziouva A, Hadjisoteriou M, Petrikkos G. Clinical evaluation of affirm VP III in the detection and identification of bacterial vaginosis. J Chemother. 2008 Dec;20(6):764-5. 8. Zappas S, Giakoupi P, Vourli S, Hatjichristodoulou Ch, Polemis M, Tzouvelekis L S, Avlami A, Daikos G L, Petrikkos G. Epidemiology of metalloenzyme producing P. aeruginosa in a tertiary hospital in Greece. Journal of Chemotherapy. 2008;20:307-11 9.Epidemiology of metalloenzyme producing P.aeruginosa in a tertiary hospital in Greece.Zappas S,Giakoup P,Vourli S,Hatzjichristodoulou Ch,Polemis M,Tzouvelekis LS,Avlami A,Daikos GL,Petrikkos G. Journal of Chemotherapy.2008;20:307-11. 10.Risk factors for coexistence of fluoroquinolone resistance and ESBL production among Enterobacteriaceae in a Greek university hospital. A.Katsandri,A.Avlamis,A.Vasilakopoulou,V.Mela,C.Kosmidis,J.Papaparaskevas and G.L.Petrikkos. Journal of Chemotherapy 2008;20:452-7. 11. G.L.Daikos, P.Petrikkos, M.Psichogiou, C.Kosmidis, E.Vryonis, A.Skoutelis, K.Georgousi, G. Petrikkos. Prospective observational study of the impact of VIM-1 metallo-β- lactamase on the outcome of patients with Kebsiella pneumoniae bloodstream infections. Antimicrobial Agents and Chemotherapy 2009;53: 1868-1873 12. Vasilakopoulou A, Psichogiou M, Tzouvelekis L, Tassios PT, Kosmidis C, Petrikkos G, Roma ES, Charvalos E, Passiotou M, Avlami A, Daikos GL. Prevalence and characterization of class 1 integrons in Escherichia coli of poultry and human origin. Foodborne Pathog Dis. 2009 Dec;6(10):1211-8. 13. Petrikkos GL. Lipid formulations of amphotericin B as first –line treatment of zygomyucosis. Clin Microbiol Infect 2009;15(5):87-92. 14.Prealbumin’ s Assessment in Hemodialysis and Renal Transplant Patients.S.Chrysostomou,Ch.Stathakis,G.Petrikkos,G.Daikos,A.Gompou,D.Perrea.Journal of Renal Nutrition 2009. 15. Skiada A, Petrikkos G. Cutaneous zygomycosis. Clin Microbiol Infect. 2009;15(5):41-5. 16. Daikos GL, Skiada A, Pavleas J, Vafiadi C, Salatas K, Tofas P, Tzanetou K, Markogiannakis A, Thomopoulos G, Vafiadi I, Petrikkos G. Serum bactericidal activity of three different dosing regiments of colistin with implications for optimum clinical use. J. Chemother 2010;22(3):175-8. 17. Van de Mortel TF, Apostolopoulou E, Petrikkos G. A comparison of the hand hygiene knowledge, beliefs, and practices of Greek nursing and medical students. Am J Infect Control 2010;38(1):75-7. 18. Skiada A, Pagano L, Groll A, Zimmerli S, Dupont B, Lagrou K, Lass-Florl C, Bouza E, Klimko N, Gaustad P, Richardson M, Hamal P, Akova M, Meis JF, Rodriguez-Tudela JL, Roilides E, Mitrousia-Ziouva A, Petrikkos G for the European Confederation of Medical Mycology Working Group on Zygomycosis. Zygomycosis in Europe: Analysis of 230 cases accrued by the registry of the European Confederation of Medical Mycology (ECMM) Working Group on Zygomycosis between 2005 and 2007. Clin Microbiol Infect2011. 19. Panagea T, Galani I, Souli M, Karantani I, Giamarellou H, Petrikkos G.Int J Antimicrob Agents. 2011 Nov;38(5):451-2. Epub 2011 Aug 15. Glycopeptide and daptomycin susceptibility and vancomycin heteroresistance of methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates from a Greek university hospital. 20. Petrikkos G, Skiada A, Lortholary O, Roilides E, Walsh TJ, Kontoyiannis DP. Clin Infect Dis. 2012 Feb;54 Suppl 1:S23-34. Review. Epidemiology and clinical manifestations of mucormycosis. 21. Spellberg B, Ibrahim A, Roilides E, Lewis RE, Lortholary O, Petrikkos G, Kontoyiannis DP, Walsh TJ.Clin Infect Dis. 2012 Feb;54 Suppl 1:S73-8. Combination therapy for mucormycosis: why, what, and how? 22. Kontoyiannis DP, Lewis RE, Lortholary O, Spellberg B, Petrikkos G, Roillides E, Ibrahim A, Walsh TJ. Clin Infect Dis. 2012 Feb;54 Suppl 1:S79-85. Erratum in: Clin Infect Dis. 2012 Apr;54(8):1220. Future directions in mucormycosis research. 23. Tsiodras S, Drogari-Apiranthitou M, Pilichos K, Leventakos K, Kelesidis T, Buitrago MJ, Petrikkos G, Panayiotides I.Am J Trop Med Hyg. 2012 Feb;86(2):261-3. Review. An unusual cutaneous tumor: African histoplasmosis following mudbaths: case report and review. 24. Collaborators (1290). HIV-CAUSAL Collaboration.Clin Infect Dis. 2012 May;54(9):136472. Epub 2012 Mar 28. Impact of antiretroviral therapy on tuberculosis incidence among HIVpositive patients in high-income countries. 25. Drogari-Apiranthitou M, Mantopoulou FD, Skiada A, Kanioura L, Grammatikou M, Vrioni G, Mitroussia-Ziouva A, Tsakris A, Petrikkos G.J Antimicrob Chemother. 2012 Apr 25. In vitro antifungal susceptibility of filamentous fungi causing rare infections: synergy testing of amphotericin B, posaconazole and anidulafungin in pairs. 26. Papadopoulos A, Pantazis N, Panagopoulos P, Kourkounti S, Xylomenos G, Chini M, Petrikkos G, Sambatakou H, Ioannidou P, Kordosis T, Panos G, Touloumi G.J Chemother. 2012;24(1):38-47. Effects of first antiretroviral regimen on lipid levels in HIV (+) individuals. 27. Lampri N, Galani I, Poulakou G, Katsarolis I, Petrikkos G, Giamarellou H, Souli M.J Antimicrob Chemother. 2012 Jun 4. Mecillinam/clavulanate combination: a possible option for the treatment of community-acquired uncomplicated urinary tract infections caused by extendedspectrum β-lactamase-producing Escherichia coli.