The Incidence of Lower Eyelid Malposition after Facial Fracture Repair: A Retrospective Study and Meta-Analysis Comparing Subtarsal, Subciliary, and Transconjunctival Incisions Emily B. Ridgway, MD, Chen Chen, Bernard T. Lee, MD Background Many incisional techniques have been described for access to the craniofacial skeleton for traumatic fracture repair including subciliary, subtarsal, and transconjunctival approaches. Each is associated with a distinct set of complications. The goal of our study was to examine lower lid malposition associated with these incisional approaches at our institution and in the literature. Methods A retrospective chart review of all operative orbital and/or zygomatic fractures treated operatively at the Beth Israel Deaconess Medical Center from 1998 to 2008 was performed. In each case, the surgical approach- specifically the lower eyelid incision and all post-operative lower eyelid complications were noted. A literature review and metaanalysis were performed of all peer-reviewed studies in the English language examining the incidence of complications of lower eyelid incisions in operative facial trauma. Results A total of 180 zygomatic and/or orbital fractures were treated operatively via at least one lower eyelid incision. Of these cases identified, the lower eyelid incisions employed were identified as subtarsal (41%), subciliary (31%), and transconjunctival (25%). The risk of ectropion was highest in subciliary incisions (12.5%, p = 0.018), however, only two cases required operative management. Entropion was found in two cases after transconjunctival incisions; both required operative management. Seventeen studies were included in the meta-analysis representing 2086 patients. The risk of ectropion was highest in subciliary (14%), entropion in transconjunctival (1.5%), and hypertrophic scarring in subtarsal incisions (3.4%). A majority of these complications resolved with conservative management. Conclusions Lower eyelid complications can be seen with all three lower eyelid incisional approaches to facial fracture repair, often resolving with conservative management. Based on our findings we favor the subtarsal approach for zygomaticomaxillary fractures and the transconjunctival incision for isolated orbital floor fractures. None of the authors have a financial interest in any of the products, devices, or drugs mentioned in this article. Table: Entropion and Ectropion Incidence by Approach Complications n (% by approach) Subtarsal n= 74 Subciliary n= 56 Transconjunctival n= 45 Laceration n= 5 Total n=180 P-Value* 2 (2.7%) 7 (12.5%) 0 0 9 (5.0%) 0.018 2 (2.7%) 6 (10.7%) 0 0 8 (4.4%) 0 1 (1.8%) 0 0 1 (0.5%) 0 0 2 (4.4%) 0 2 (1.1%) Conservatively managed 0 0 0 0 0 Operatively managed 0 0 2 (4.4%) 0 2 (1.1%) Lid Edema 1 (1.4%) 5 (8.9%) 0 1 (20%) 7 (3.9%) .016 Hypertrophic Scar 1 (1.4%) 2 (3.6%) 0 0 3 (1.7%) .545 Total 4 (5.4%) 14 (25%) 2 (4.4%) 1 (20%) 21 (11.7%) Total Ectropion Conservatively managed Operatively managed Total Entropion * Fisher’s Exact Test 0.108 Table: Meta-Analysis of Entropion and Ectropion Incidence by Approach Complications n (% by approach) Subtarsal n= 238 Subciliary n= 470 Transconjunctival n= 1378 Total n=2086 P-Value* 9 (3.8%) 68 (14%) 20 (1.5%) 97 (4.7%) <0.001 Conservatively managed 8 (3.4%) 54 (11%) 4 (0.3%) 66 (3.2%) Operatively managed 1 (0.4%) 14 (3.0%) 16 (1.2%) 31 (1.5%) 0 1 (0.2%) 9 (0.7%) 10 (0.5%) Conservatively managed 0 0 4 (0.3%) 4 (0.2%) Operatively managed 0 1 (0.2%) 5 (0.4%) 6 (0.3%) Lid Edema 6 (2.5%) 17 (3.6%) 0 23 (1.1%) <0.001 Hypertrophic Scar 8 (3.4%) 4 (0.9%) 0 12 (0.6%) <0.001 Total 23 (9.7%) 90 (19.1%) 29 (2.1%) 142 (6.8%) Total Ectropion Total Entropion * Fisher’s Exact Test 0.42 REFERENCES 1. Converse J. Two plastic operations for repair of orbit following severe trauma and extensive comminuted fracture. Arch Opthalmol. 1944; 31: 323-325. 2. Wray RC, Holtmann BN, Ribaudo JM et al. A comparison of conjunctival and subciliary incisions for orbital fractures. Br. J. Plast. Surg. 1977; 30: 142. 3. Rohrich RJ, Janis JE, Adams WP: Subciliary versus subtarsal approaches to orbitozygomatic fractures. Plast Reconst Surg 2003; 111: 1708. 4. Bourquet J. Les hernies graisseuse de l’orbite. Notre traitement chirurgical. Bull Acad Med (Paris) 1924; 92: 1270. 5. Tessier P. The conjunctival approach to the orbital floor and maxilla in congential malformation and trauma. J Maxillofacial Surg. 1973; 1: 3-8.