Publications referencing performed MRI Analysis http://scholar.harvard.edu/mri/publications (Cline, Lorensen et al. 1990; Colchester, Hawkes et al. 1991; Lemke, Rhodes et al. 1991; Kikinis, Shenton et al. 1992; Khoury, Guttmann et al. 1994; Guttmann, Ahn et al. 1995; Hohol, Guttmann et al. 1997; Warfield, Robatino et al. 1998; Guttmann, Kikinis et al. 1999; Khoury, Orav et al. 1999; Kikinis, Guttmann et al. 1999; Guttmann, Benson et al. 2000; Guttmann, Warfield et al. 2000; Khoury, Guttmann et al. 2000; Weiner, Guttmann et al. 2000; Sperling, Guttmann et al. 2001; Wei, Warfield et al. 2002; Wei, Guttmann et al. 2004; Database 2005; Liu, Meier et al. 2005; Guttmann, Meier et al. 2006; Meier and Guttmann 2006; Wu, Warfield et al. 2006; Glanz, Holland et al. 2007; Bakshi, Neema et al. 2008; Duan, Hildenbrand et al. 2008; Liptak, Berger et al. 2008; Viglietta, Bourcier et al. 2008; Gauthier, Berger et al. 2009; Gauthier, Glanz et al. 2009; Healy, Ali et al. 2009; Neema, Arora et al. 2009; Sampat, Berger et al. 2009; Healy, Liguori et al. 2010; Khoury, Healy et al. 2010; Sampat, Healy et al. 2010; Xia, Chibnik et al. 2010; Liguori, Healy et al. 2011; Liguori, Meier et al. 2011; Gholipour, Egorova et al. 2012; Holland, Charil et al. 2012; Moodie, Healy et al. 2012; Bove, Musallam et al. 2013; Coronado WM 2013; Kivisakk, Healy et al. 2013; Xia, Secor et al. 2013; Gandhi, Healy et al. 2013 ) Bakshi, R., M. 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"Segmentation of subtraction images for the measurement of lesion change in multiple sclerosis." AJNR Am J Neuroradiol 29(2): 340-6. Gandhi, R., B. Healy, et al. (2013 ). "Circulating microRNAs as biomarkers for disease staging in multiple sclerosis." Ann Neurol 73(6): 729-40. Gauthier, S. A., A. M. Berger, et al. (2009). "Rate of brain atrophy in benign vs early multiple sclerosis." Arch Neurol 66(2): 234-7. Gauthier, S. A., B. I. Glanz, et al. (2009). "Incidence and factors associated with treatment failure in the CLIMB multiple sclerosis cohort study." J Neurol Sci 284(1-2): 116-9. Gholipour, T., MD, , S. Egorova, PhD, , et al. (2012). MRI Characteristics of Malignant Multiple Sclerosis. The 64th Annual Meeting of the American Academy of Neurology. Glanz, B. I., C. M. Holland, et al. (2007). "Cognitive dysfunction in patients with clinically isolated syndromes or newly diagnosed multiple sclerosis." Mult Scler 13(8): 1004-10. Guttmann, C. R., S. S. Ahn, et al. (1995). "The evolution of multiple sclerosis lesions on serial MR." AJNR Am J Neuroradiol 16(7): 1481-91. Guttmann, C. R., R. Benson, et al. (2000). "White matter abnormalities in mobilityimpaired older persons." Neurology 54(6): 1277-83. Guttmann, C. R., R. Kikinis, et al. (1999). "Quantitative follow-up of patients with multiple sclerosis using MRI: reproducibility." J Magn Reson Imaging 9(4): 50918. Guttmann, C. R., D. S. Meier, et al. (2006). "Can MRI reveal phenotypes of multiple sclerosis?" Magn Reson Imaging 24(4): 475-81. Guttmann, C. R. G., S. K. Warfield, et al. (2000). "Variability of Brain Atrophy Estimates in Multiple Sclerosis." Proc.Intl.Soc.Mag.Reson.Med. 8(4): 1188. Healy, B. C., E. N. Ali, et al. (2009). "Smoking and disease progression in multiple sclerosis." Arch Neurol 66(7): 858-64. Healy, B. C., M. Liguori, et al. (2010). "HLA B*44: protective effects in MS susceptibility and MRI outcome measures." Neurology 75(7): 634-40. Hohol, M. J., C. R. Guttmann, et al. (1997). "Serial neuropsychological assessment and magnetic resonance imaging analysis in multiple sclerosis." Arch Neurol 54(8): 1018-25. Holland, C. M., A. Charil, et al. (2012). "The relationship between normal cerebral perfusion patterns and white matter lesion distribution in 1,249 patients with multiple sclerosis." J Neuroimaging 22(2): 129-36. Khoury, S. J., C. R. Guttmann, et al. (1994). "Longitudinal MRI in multiple sclerosis: correlation between disability and lesion burden." Neurology 44(11): 2120-4. Khoury, S. J., C. R. Guttmann, et al. (2000). "Changes in activated T cells in the blood correlate with disease activity in multiple sclerosis." Arch Neurol 57(8): 1183-9. Khoury, S. J., B. C. Healy, et al. (2010). "A randomized controlled double-masked trial of albuterol add-on therapy in patients with multiple sclerosis." Arch Neurol 67(9): 1055-61. Khoury, S. J., E. J. Orav, et al. (1999). "Changes in serum levels of ICAM and TNF-R correlate with disease activity in multiple sclerosis." Neurology 53(4): 758-64. Kikinis, R., C. R. Guttmann, et al. (1999). "Quantitative follow-up of patients with multiple sclerosis using MRI: technical aspects." J Magn Reson Imaging 9(4): 519-30. Kikinis, R., M. E. Shenton, et al. (1992). "Routine quantitative analysis of brain and cerebrospinal fluid spaces with MR imaging." J Magn Reson Imaging 2(6): 61929. Kivisakk, P., B. C. Healy, et al. (2013). "Evaluation of circulating osteopontin levels in an unselected cohort of patients with multiple sclerosis: relevance for biomarker development." Mult Scler. Lemke, H., M. Rhodes, et al. (1991). Segmentation of Dual-Echo MR Head Data. Computer Assisted Radiology / Computergestützte Radiologie, Springer Berlin Heidelberg: 606-611. Liguori, M., B. C. Healy, et al. (2011). "HLA (A-B-C and -DRB1) alleles and brain MRI changes in multiple sclerosis: a longitudinal study." Genes Immun 12(3): 183-90. Liguori, M., D. S. Meier, et al. (2011). "One year activity on subtraction MRI predicts subsequent 4 year activity and progression in multiple sclerosis." J Neurol Neurosurg Psychiatry 82(10): 1125-31. Liptak, Z., A. M. Berger, et al. (2008). "Medulla oblongata volume: a biomarker of spinal cord damage and disability in multiple sclerosis." AJNR Am J Neuroradiol 29(8): 1465-70. Liu, L., D. Meier, et al. (2005). "Multiple sclerosis medical image analysis and information management." J Neuroimaging 15(4 Suppl): 103S-117S. Meier, D. S. and C. R. Guttmann (2006). "MRI time series modeling of MS lesion development." Neuroimage 32(2): 531-7. Moodie, J., B. C. Healy, et al. (2012). "Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: a longitudinal study." J Neurol Sci 315(1-2): 49-54. Neema, M., A. Arora, et al. (2009). "Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis." J Neuroimaging 19(1): 3-8. Sampat, M. P., A. M. Berger, et al. (2009). "Regional white matter atrophy--based classification of multiple sclerosis in cross-sectional and longitudinal data." AJNR Am J Neuroradiol 30(9): 1731-9. Sampat, M. P., B. C. Healy, et al. (2010). "Disease modeling in multiple sclerosis: assessment and quantification of sources of variability in brain parenchymal fraction measurements." Neuroimage 52(4): 1367-73. Sperling, R. A., C. R. Guttmann, et al. (2001). "Regional magnetic resonance imaging lesion burden and cognitive function in multiple sclerosis: a longitudinal study." Arch Neurol 58(1): 115-21. Viglietta, V., K. Bourcier, et al. (2008). "CTLA4Ig treatment in patients with multiple sclerosis: an open-label, phase 1 clinical trial." Neurology 71(12): 917-24. Warfield, S., A. Robatino, et al. (1998). Nonlinear Registration and Template Driven Segmentation. Brain Warping. A. W. Toga. Wei, X., C. R. Guttmann, et al. (2004). "Has your patient's multiple sclerosis lesion burden or brain atrophy actually changed?" Mult Scler 10(4): 402-6. Wei, X., S. K. Warfield, et al. (2002). "Quantitative analysis of MRI signal abnormalities of brain white matter with high reproducibility and accuracy." J Magn Reson Imaging 15(2): 203-9. Weiner, H. L., C. R. Guttmann, et al. (2000). "Serial magnetic resonance imaging in multiple sclerosis: correlation with attacks, disability, and disease stage." J Neuroimmunol 104(2): 164-73. Wu, Y., S. K. Warfield, et al. (2006). "Automated segmentation of multiple sclerosis lesion subtypes with multichannel MRI." Neuroimage 32(3): 1205-15. Xia, Z., L. B. Chibnik, et al. (2010). "A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis." PLoS One 5(11): e14169. Xia, Z., E. Secor, et al. (2013). "Modeling disease severity in multiple sclerosis using electronic health records." PLoS One 8(11): e78927.