Andrea White 28- year old female Experience strange “pins & needles” feeling in hands and feet Very tired Feels weak when being active Feels depressed Vision getting worse Unsteadiness when walks Symptoms come and go Fatigue & balance problems Majority of time feels fine In high school was a gymnast Never had problems with balance before Multiple sclerosis is a condition that's called an autoimmune disease, a chronic condition and a neurological disease. Common symptoms Fatigue- Occurs in as many as 78% of patients, usually in the late afternoon and often subsides in the early evening. Weakness Spasticity Balance problems- Balance problems without vertigo may be more constant, causing the person to sway or stagger Bladder and bowel problems Numbness- 55% of patients have this symptom. Disturbances of feeling in the extremities or the trunk such as tingling, crawling sensations, feelings of swelling or numbness. Numbness also depends upon its cause. If severe neurological damage to the myelin sheath takes place, then numbness may remain. Vision loss Tremors Depression Tingling Relapsing-Remitting This is the most common form of multiple sclerosis. About 85% of people with MS are initially diagnosed. People with this have temporary periods called relapses, flare-ups or exacerbations, when new symptoms appear. Secondary-Progressive symptoms worsen more steadily over time, with or without the occurrence of relapses and remissions. Most people who are diagnosed with RRMS will transition to SPMS at some point Primary-Progressive. This type if MS is not very common, occurring in about 10% of people with MS. This is characterized by slowly worsening symptoms from the beginning, with no relapses or remissions Progressive-Relapsing A rare form of MS (5%), PRMS is characterized by a steadily worsening disease state from the beginning, with acute relapses but no remissions, with or without recovery Vision- Occipital Lobe of Cerebrum Muscle Coordination- Cerebellum Happiness- Amygdala & frontal lobe of cerebrum Sleeping- Brain stem & Pineal gland Balance when walking- Cerebrum Bodily sensations, Pain- Parietal Lobe of Cerebrum LESION LOCATION: Cerebrum & Cerebellum Motor nerve tracts SIGNS/SYMPTOMS: Balance problems, speech problems, coordination, tremors Muscle weakness, spasticity paralysis, vision problems, bladder, bowel problems Sensory nerve Altered sensation, numbness, prickling, burning tract sensation Most likely MS occurs as a result of some combination of genetic, environmental and infectious factors, and possibly other factors like vascular problems. Epidemiological studies of MS have provided hints on possible causes for the disease. Theories try to combine the known data into plausible explanations, but none has proved definitive. Life expectance 5-10 years MS can also lead to some major life changes such as loss of mobility and interference with work. Thus the person with MS faces significant challenges in coping with a potentially stressful life. STRESS!! Have to participate in stress management. Inappropriate behavior Loss of interest Emotional lack Adjustment to disability Fear of injury Fear of change Clarification of functional limitations Factors affecting motivation and benefits of working Employer and worker expectations Resume and cover letter writing Job interviewing Job accommodations (American Disabilities Act) A few different treatments but no CURE Main treatment is Interferon Beta 1A: Is a drug in the used to treat (MS).It is produced by mammalian cells, while Interferon Beta 1b is produced in modified E coil. Interferon's have been shown to produce about a 18–38% reduction in the rate of MS relapses. There is currently no cure for MS. Starting a course of interferon's early may slow its progress. Medicine for depression Multiple sclerosis is an autoimmune and neurologic condition. Usually, neurologists are more familiar with multiple sclerosis and they are the ones who diagnose it. This is due to the fact that MS scars the brain, and this can be easily seen on and MRI. Neurologist Physician specialized in neurology and trained to investigate and diagnose and treat neurological disorders. Also, after being treated with MS it is recommended that you see an emotion coach/ therapist