Guidelines for Flexible Bronchoscopy, Esophagoscopy, Esophageal Dilation and Photodynamic/Laser Therapy Equipment: 1. 2. 3. 4. 5. Dental Guard (supplied by OR staff) Portex Adapter (for flexible bronchoscopy) Bard infusion pump with Propofol plate Standard anesthesia set-up 8.0 endotracheal tube (need this for bronchoscopy/EGD performed using GETA) IV Access: Preferably at least a 20 or 18 gauge intravenous line, however, many patients arrive to the holding area with a 22 gauge already in place. If the intravenous line is functional, you may proceed. Use you judgement. Drugs: 1. 2. 3. 4. 5. In the holding area, midazolam may be administered if appropriate. Fentanyl may be added if appropriate. Topical airway anesthetics (i.e., cetacaine spray, nebulized lidocaine and/or pontocaine, 4% viscous lidocaine, 4% lidocaine ointment administered individually or in combination). Consult with MD* for their preference as this will vary. Propofol Odansetron, reglan, dexamethasone as needed Bronchodilators, lidocaine, ephedrine, phenylephrine, epinephrine and glycopyrrolate should be available in addition to the standard anesthetic agents. Perioperative Management: Induction and maintenance: (assumes procedure is performed via MAC) 1. Following placement of standard monitors, oxygen should be administered via face mask or nasal cannula. 2. Patients having flexible bronchoscopy should be placed in the supine position. Patients for esophagoscopy should be placed in the left lateral decubitus position. 3. The majority of these procedures may be performed using monitored anesthesia care (MAC) with intravenous sedation. However, some patients (particularly those with esophageal obstruction, nausea and vomiting prior to the procedure) will require general anesthesia. Consult MD for their preference. 4. For flexible bronchoscopy during MAC, please remember to topicalize the patient’s nares, as the scope will be passed via the nose. Erin A Sullivan, MD Page 1 4/27/2016 *MD within the text of these guidelines refers to the attending anesthesiologist responsible for the case. Guidelines for Flexible Bronchoscopy, Esophagoscopy, Esophageal Dilation and Photodynamic/Laser Therapy (continued) Perioperative Management: Induction and maintenance: (assumes procedure is performed via MAC) 5. 6. 7. In addition to intravenous midazolam, propofol may be administered as needed either by continuous infusion or intravenous bolus in order to provide adequate sedation during the procedure. If photodynamic therapy or laser therapy will be performed, please ensure that the patient is wearing the appropriate eye protection. Always be prepared to manage an airway fire, particularly when laser therapy is being performed. In order to reduce the possibility of an airway fire, use an FiO2 of < 35%. Emergence and recovery: 1. At the conclusion of the procedure, the patient should be awake and functioning at their neurologic baseline with intact airway reflexes. 2. Most of these patients may be sent to the PACU as a backthrough (Holding/Phase II). Please place the patient on oxygen (if necessary) and a pulse oximeter while they are waiting for the escort service to transport them to their destination. 3. Some patients require a generous amount of sedation for their procedure. Please admit these patients to the PACU for recovery (PACU/Phase I) if they do not meet appropriate discharge criteria. Erin A Sullivan, MD Page 2 4/27/2016 *MD within the text of these guidelines refers to the attending anesthesiologist responsible for the case. Guidelines for Rigid Bronchoscopy Equipment: 1. See Guidelines for flexible bronchoscopy 2. Jet ventilator 3. Arterial and central venous line transducers if appropriate 4. BIS or PSA 4000 monitor IV Access: 18 or 16 gauge intravenous access if possible. Drugs: 1. 2. 3. 4. See Guidelines for flexible bronchoscopy (consult with MD) Induction agent of choice; propofol works best since you will not be able to use a volatile agent during the rigid bronchoscopy/jet ventilation Muscle relaxant: a nondepolarizing neuromuscular blocking agent such as rocuronium usually works well. Cefazolin is the most frequently administered antibiotic for patients who are not allergic to penicillin or other cephalosporins. Perioperative Management: Induction and maintenance: 1. Following the placement of standard monitors + any appropriate invasive monitors, preoxygenate the patient and administer the appropriate general anesthetic agents. 2. Secure the patient’s airway using at least an 8.0 endotracheal tube. 3. During rigid bronchoscopy, the surgeon will extubate the patient prior to insertion of the rigid scope. Be prepared to jet ventilate the patient! 4. The trachea will be reintubated at the conclusion of the rigid bronchoscopy. Emergence and recovery: 1. Proceed in the standard fashion for patients receiving general anesthesia. 2. Patients should be recovered in the PACU prior to discharge to the floor. Erin A Sullivan, MD Page 3 4/27/2016 *MD within the text of these guidelines refers to the attending anesthesiologist responsible for the case. Guidelines for Mediastinoscopy Equipment: 1. 2. 3. 4. Standard equipment Arterial line transducer if appropriate Central venous line transducer if appropriate BIS or PSA 4000 monitor IV Access: 18 or 16 gauge intravenous access is preferred. Consult with MD regarding the need for central venous access. Drugs: 1. 2. 3. In the holding area, midazolam may be administered if appropriate. Fentanyl may be added if appropriate. Standard anesthetic medications, muscle relaxants and emergency drugs Cefazolin is most often administered to patients who are not penicillin or cephalosporin allergic. Blood/Blood Products: Consult with MD regarding the need for type and screen or type and crossmatch. Perioperative Management: Induction and maintenance: 1. The endotracheal tube should be secured to the patient’s left side. This will keep the tube out of the surgical field. 2. Consider placing the blood pressure cuff and arterial lines on opposite arms. If an arterial line is not used, consider placing a pulse oximeter probe on each side. These monitors may assist with early detection of innominate artery compression. 3. General anesthesia is required for mediastinoscopy. Discuss plan with MD. 4. Patients with Eaton-Lambert Syndrome (resulting from oat cell carcinoma) are sensitive to succinylcholine and nondepolarizing muscle relaxants. Reduced doses are necessary. Emergence: 1. Extubate the patient when they are appropriately responsive and exhibit the full return of protective airway reflexes. 2. Patients should be admitted to the PACU. Erin A Sullivan, MD Page 4 4/27/2016 *MD within the text of these guidelines refers to the attending anesthesiologist responsible for the case. Guidelines for Open Lung Biopsy (Wedge Resection of Lung Lesion) Equipment: 1. 2. 3. 4. 5. 6. 7. Fiberoptic bronchoscope with light source Single lumen (8.0) and double lumen endotracheal tubes Large clamp for the double lumen endotracheal tube Lower body Bair Hugger CPAP connectors and PEEP valve (usually 5 cm of H2O is sufficient) Arterial and central venous line transducers if needed BIS or PSA 4000 monitor IV Line Access: 18 or 16 gauge intravenous line is preferred. Consult with MD regarding the need for arterial line and/or central venous access. Drugs: 1. 2. 3. 4. 5. Standard anesthetic medications, muscle relaxants and emergency drugs In the holding area, midazolam may be administered if appropriate. Fentanyl may be added if appropriate. Odansetron, reglan, dexamethasone as needed Bronchodilators with adapter for the anesthesia circuit Cefazolin is most often administered to patients who are not penicillin or cephalosporin allergic. Blood/Blood Products: Check for the availability of type and screen/type and crossmatch. Consult with MD regarding the need for blood/blood products. Perioperative Management: Induction and maintenance: 1. Following the placement of standard monitors + any appropriate invasive monitors (which may be placed after the induction of anesthesia; consult MD), preoxygenate the patient and administer the appropriate general anesthetic agents. 2. First, secure the patient’s airway using at least an 8.0 endotracheal tube if flexible bronchoscopy is going to be performed. Drs. Ferson and Buenaventura usually prefer securing the patient’s airway with a doublelumen endotracheal tube from the very beginning. They will usually instruct otherwise if this is not his plan. 3. The single lumen endotracheal tube will be changed to a double lumen endotracheal tube in order to perform the thoracoscopic open lung biopsy. Confirm the correct placement of the double lumen endotracheal tube with fiberoptic bronchoscopy. 4. The patient will be placed in the lateral decubitus position with the operative (nondependent) lung facing up. Erin A Sullivan, MD Page 5 4/27/2016 *MD within the text of these guidelines refers to the attending anesthesiologist responsible for the case. Guidelines for Open Lung Biopsy (Wedge Resection of Lung Lesion) (continued) Perioperative Management: Induction and maintenance: 5. Maintenance of anesthesia may be achieved with a balanced general anesthetic technique of choice. 6. Most patients will require the use of either oxygen alone or an oxygen/air combination during single lung ventilation. You will achieve better lung deflation if you use 100% oxygen prior to isolating the operative lung. If hypoxemia occurs or persists during single lung ventilation on 100% oxygen, verify endobronchial tube placement and position; consider adding 5 cm H2O CPAP to the nondependent lung (the collapsed lung); if this does not correct hypoxemia consider adding PEEP to the dependent lung (the “down” or ventilated lung); if none of the above maneuvers corrects the hypoxemia, convert back to double lung ventilation (reinflate the operative lung). Caution: you may not be able to utilize CPAP during thoracoscopic procedures since this will impede the surgeon’s operative field due to re-expansion of the operative lung. Consult with the MD. Emergence and recovery: 1. Extubate the patient in the OR when/if they meet the appropriate criteria. If the patient does not meet extubation criteria, consider changing the double lumen endotracheal tube to a single lumen endotracheal tube and mechanically ventilate the patient until he/she meets the appropriate extubation criteria. 2. Transfer the patient to the PACU or ICU with oxygen delivered either by facemask or endotracheal tube. Notes about patient positioning: Positioning of the “up” arm varies according to the surgeon’s preference: 1. Drs. Luketich, Christie, and Fernando place their patients on a beanbag with the operative arm in a Velcro sling that is suspended from a bar. 2. Drs. Ferson and Buenaventura position the “up” arm on an overhead arm board. 3. Make sure that the axillary roll is placed in the proper position in order to minimize the chance of a brachial plexus injury. 4. Make judicious use of eggcrate to pad all pressure points! 5. Make sure that the patient’s head is maintained in the neutral position. Erin A Sullivan, MD Page 6 4/27/2016 *MD within the text of these guidelines refers to the attending anesthesiologist responsible for the case. Guidelines for Thoracoscopy (Wedge Resection, Lobectomy, Bullectomy, Laparoscopic Esophagectomy, Pericardial Window) Equipment: 1. 2. 3. 4. 5. 6. 7. 8. Fiberoptic bronchoscope with light source Single lumen (8.0) and double lumen endotracheal tubes Large clamp for the double lumen endotracheal tube Lower body Bair Hugger CPAP connectors and PEEP valve (usually 5 cm of H2O is sufficient) Arterial and central venous line and pulmonary artery transducers if needed (Consult with MD) Epidural kit (Consult with MD) BIS or PSA 4000 monitors IV Line Access: 18 or 16 gauge intravenous line is preferred. Consult with MD regarding the need for central venous access. If the patient is scheduled for laparoscopic esophagectomy and you desire central venous access, please place the CVP line on the right side, as the surgeons will perform their esophageal pull-through on the left side of the neck. Drugs: 1. 2. 3. 4. 5. Standard anesthetic medications, muscle relaxants and emergency drugs In the holding area, midazolam may be administered if appropriate. Fentanyl may be added if appropriate. Odansetron, reglan, dexamethasone as needed Bronchodilators with adapter for the anesthesia circuit 0.25%-0.5% bupivacaine or 2% lidocaine for epidural injection (if TEA will be used;consult with MD regarding the use of epidural narcotics intraoperatively) Blood/Blood Products: Check on availability of type and screen/type and crossmatch. Consult with MD regarding the need for blood/blood products. Perioperative Management: Induction and maintenance: 1. Following the placement of standard monitors + any appropriate invasive monitors (which may be placed after induction of anesthesia; consult MD)and TEA if desired, preoxygenate the patient and administer the appropriate general anesthetic agents. 2. First, secure the patient’s airway using at least an 8.0 endotracheal tube if flexible bronchoscopy or laparoscopic esophagectomy is going to be performed. Drs. Ferson and Buenaventura prefer to secure the patient’s airway with a double-lumen endotracheal tube from the very beginning Erin A Sullivan, MD Page 7 4/27/2016 *MD within the text of these guidelines refers to the attending anesthesiologist responsible for the case. Guidelines for Thoracoscopy (Wedge Resection, Lobectomy, Bullectomy, Laparoscopic Esophagectomy, Pericardial Window) (continued) (except during esophagectomy). They will usually instruct otherwise if this is not the plan. Perioperative Management: Induction and maintenance: 1. The single lumen endotracheal tube will be changed to a double lumen endobronchial tube in order to perform the thoracoscopic procedure. Confirm the correct placement of the double lumen endobronchial tube with fiberoptic bronchoscopy. 2. The patient will be placed in the lateral decubitus position with the operative lung facing up (non-dependent lung). 3. Maintenance of anesthesia may be achieved with a balanced general anesthetic technique of choice + thoracic epidural anesthesia. 4. Most patients will require the use of either oxygen alone or an oxygen/air combination during single lung ventilation. You will achieve better lung deflation by administering 100% oxygen prior to isolating the lung. If hypoxemia occurs or persists during single lung ventilation on 100% oxygen, verify endotracheal tube placement and position; consider adding 5 cm H2O CPAP to the non-dependent lung (the collapsed lung); if this does not correct hypoxemia consider adding PEEP to the dependent lung (the “down” or ventilated lung); if none of the above maneuvers corrects the hypoxemia, convert back to double lung ventilation (reinflate the operative lung). During thoracoscopy, CPAP may interfere with the operative field. Consult with the MD. 5. The MD may elect to insert a thoracic epidural catheter either preoperatively or immediately postoperatively in order to provide analgesia. Alternatively, the surgeon may perform intercostal nerve blocks or insert an intrapleural catheter at the conclusion of the operation. Any of these procedures may be helpful for the patient if it is necessary to convert the thoracoscopic procedure to an open thoracotomy, but a functioning thoracic epidural catheter is often best. Emergence and recovery: 1. Extubate the patient in the OR when/if they meet the appropriate criteria. If the patient does not meet appropriate extubation criteria, consider changing the double lumen endobronchial tube to a single lumen endotracheal tube and mechanically ventilating the patient in the PACU or ICU until they meet appropriate extubation criteria. 2. Transfer the patient to the PACU or ICU with oxygen delivered either by facemask or endotracheal tube. 3. See Guidelines for TEA if a thoracic epidural catheter is used for pain management. Erin A Sullivan, MD Page 8 4/27/2016 *MD within the text of these guidelines refers to the attending anesthesiologist responsible for the case. Guidelines for Thoracoscopy (Wedge Resection, Lobectomy, Bullectomy, Laparoscopic Esophagectomy, Pericardial Window) (continued) Notes about patient positioning: Positioning of the “up” arm varies according to the surgeon’s preference: 1. Drs. Luketich, Christie, and Fernando place their patients on a beanbag with the operative arm in a Velcro sling that is suspended from a bar. 2. Drs. Ferson and Buenaventura position the “up” arm on an overhead arm board. 3. Make sure that the axillary roll is placed in the proper position in order to minimize the chance of a brachial plexus injury. 4. Make judicious use of eggcrate to pad all pressure points! 5. Make sure that the patient’s head is maintained in the neutral position. Erin A Sullivan, MD Page 9 4/27/2016 *MD within the text of these guidelines refers to the attending anesthesiologist responsible for the case. Guidelines for Thoracotomy Equipment: 1. 2. 3. 4. 5. 6. 7. 8. 9. Fiberoptic bronchoscope with light source Single lumen (8.0) and double lumen endotracheal tubes Large clamp for the double lumen endotracheal tube Lower body Bair Hugger CPAP connectors and PEEP valve (usually 5 cm of H2O is sufficient) Arterial and central venous line and pulmonary artery transducers if needed (Consult with MD) Blood warmer, not primed Epidural catheter insertion kit, local anesthetic for nerve block (preservative-free), and infusion pump (may use Bard pump with generic faceplate). Consult with MD regarding the use of epidural narcotics. BIS or PSA 4000 monitor IV Line Access: 18 or 16 gauge intravenous line is preferred. Consult with MD regarding the need for central venous access. Drugs: 1. 2. 3. 4. Standard anesthetic medications, muscle relaxants and emergency drugs In the holding area, midazolam may be administered if appropriate. Fentanyl may be added if appropriate. Odansetron, reglan, dexamethasone as needed Bronchodilators with adapter for the anesthesia circuit Blood/Blood Products: Check the availability of type and screen/type and crossmatch. Consult with MD regarding the need for blood/blood products. Perioperative Management: Induction and maintenance: 1. Following the placement of standard monitors + any appropriate invasive monitors (which may be placed after induction of anesthesia; consult MD) and thoracic epidural catheter (if desired), preoxygenate the patient and administer the appropriate general anesthetic agents. 2. First, secure the patient’s airway using at least an 8.0 endotracheal tube if flexible bronchoscopy is going to be performed. Drs. Ferson and Buenaventura prefer to secure the patient’s airway with a double-lumen endobronchial tube from the very beginning. They will usually instruct otherwise if this is not the plan. 3. The single lumen endotracheal tube will be changed to a double lumen endobronchial tube in order to perform the thoracotomy. Confirm the Erin A Sullivan, MD Page 10 4/27/2016 *MD within the text of these guidelines refers to the attending anesthesiologist responsible for the case. Guidelines for Thoracotomy (continued) correct placement of the double lumen endotracheal tube with fiberoptic bronchoscopy. Perioperative Management: Induction and maintenance: 1. The patient will be placed in the lateral decubitus position with the operative lung facing up. 2. Maintenance of anesthesia may be achieved with a balanced general anesthetic technique of choice + thoracic epidural anesthesia. 3. Most patients will require the use of either oxygen alone or an oxygen/air combination during single lung ventilation. If hypoxemia occurs or persists during single lung ventilation on 100% oxygen, verify endotracheal placement and position; consider adding 5 cm H2O CPAP to the non-dependent lung (the “up” or collapsed lung); if this does not correct hypoxemia consider adding PEEP to the dependent lung (the “down” or ventilated lung); if none of the above maneuvers corrects the hypoxemia, convert back to double lung ventilation (reinflate the operative lung). Consult with the MD. 4. The MD may elect to insert a thoracic epidural catheter either preoperatively or immediately postoperatively in order to provide analgesia. Alternatively, the surgeon may perform intercostal nerve blocks or insert an intrapleural catheter at the conclusion of the operation. Emergence and recovery: 1. Extubate the patient in the OR when/if they meet the appropriate criteria. If the patient does not meet appropriate extubation criteria, consider changing the double lumen endobronchial tube to a single lumen endotracheal tube. 2. Transfer the patient to the PACU or ICU with oxygen delivered either by facemask or endotracheal tube. 3. Follow the Guidelines for TEA if a thoracic epidural catheter is used. Notes about patient positioning: Positioning of the “up” arm varies according to the surgeon’s preference: 1. Drs. Luketich, Christie, and Fernando place their patients on a beanbag with the operative arm in a Velcro sling that is suspended from a bar. 2. Drs. Ferson and Buenaventura position the “up” arm on an overhead arm board. 3. Make sure that the axillary roll is placed in the proper position in order to minimize the chance of a brachial plexus injury. 4. Make judicious use of eggcrate to pad all pressure points! 5. Make sure that the patient’s head is maintained in the neutral position. Erin A Sullivan, MD Page 11 4/27/2016 *MD within the text of these guidelines refers to the attending anesthesiologist responsible for the case.