David M. Kaylie, M.D. Work Address: The Otology Group 300 20th Ave. N Suite 502 Nashville, TN 37203 Work Phone: (615) 284-4444 E-mail: dkaylie@comcast.net dkaylie@hotmail.com Education 1983-1987 Wilton High School, Wilton CT 1987-1991 Tufts University; B.S. Biology, B.A. Philosophy 1990 School for Field Studies, Queensland, Australia; Rainforest Ecology 1992-1993 Medical College of Virginia; M.S. Neuroanatomy 1993-1997 Medical College of Virginia; M.D. Post-Graduate Education 1997-1998 Internship, Department of General Surgery, Oregon Health Sciences University, Portland, OR 1998-2002 Resident, Department of Otolaryngology – Head and Neck Surgery, Oregon Health Sciences University, Portland, OR 97201 2002-2004 Fellow, The Otology Group 300 20th Ave. N. Suite 502 Nashville, TN 37203 (615) 284-4444 Appointments 2002-2004 Clinical Instructor, Department of Otolaryngology S-2100 Medical Center North Vanderbilt University Medical Center Nashville, TN 37232 (615) 322-7267 2004-Present Assistant Professor, Department of Otolaryngology S-2100 Medical Center North Vanderbilt University Medical Center Nashville, TN 37232 (615) 322-7267 Memberships American Academy of Otolaryngology – Head and Neck Surgery Associate Fellow American College of Surgeons Academic Honors Ciba-Geigy book award 1997 Basic Science Research 1989-1990 Investigation of trans-membrane amino-acids in MHC class II molecules. Department of Surgery, Harvard Medical School, Massachusetts General Hospital; Advisor: Jerry Wanick, PhD. 1991-1992 Investigation of dystrophin gene and Duchenne muscular dystrophy. Department of Pediatrics, Division of Genetics, Harvard Medical School, Boston Children’s Hospital; Advisor: Louis Kunkel, PhD. 1992-1993 Investigation of hypoglossal nucleus degeneration in amyotrophic lateral sclerosis. Department of Anatomy, Medical College of Virginia; Advisor: Robert Spencer, PhD. and Ross McLung, PhD. 1999-2000 Investigation of anti-DNA receptor autoantibodies in autoimmune sensorineural hearing loss. Oregon Hearing Research Center, Department of Otolaryngology-Head and Neck Surgery, Oregon Health Sciences University; Advisor: Dennis Trune, PhD. 1999-2000 Investigation of inner ear effects of steroid therapy on autoimmune sensorineural hearing loss. Oregon Hearing Research Center, Department of Otolaryngology-Head and Neck Surgery, Oregon Health Sciences University; Advisor: Dennis Trune, PhD. 2002-Present Laser Doppler flowmetry measurements of cranial nerves during skull base surgery for preservation of function The Otology Group, Nashville TN; Advisor: C. Gary Jackson Clinical Research (on going) 1) Evaluation of hearing preservation after trans-crusal petrosal craniotomy 2) Blood flow dynamics in the internal auditory canal during acoustic neuroma surgery 3) Facial nerve and muscle imaging as a pre-operative predictor of facial function after acoustic neuroma surgery Scientific Presentations and Courses 1) Current treatment practices for early laryngeal carcinoma. Oral presentation. Annual Meeting American Academy of Otolaryngology Head and Neck Surgery, San Francisco, CA September 7-10, 1997. 2) External beam radiation followed by planned neck dissection and brachytherapy for base of tongue squamous cell carcinoma. Oral presentation. Western Section of the Triologic Society, San Francisco CA, January 8-9, 2000. 3) Modern acoustic neuroma surgery outcomes. Oral presentation. Western Section of the Triologic Society, San Francisco, CA, January 8-9, 2000. 4) Surgery versus gamma knife: A meta-analysis comparison of outcomes. Triologic Society Spring Meeting, Orlando, FL, May 12-18, 2000. 5) Decreased cochlear DNA receptor staining in autoimmune hearing loss. Annual Meeting American Academy of Otolaryngology – Head and Neck Surgery, AAO-HNSF/ARO Research Forum. Washington, D.C. September 24-27, 2000. 6) Massive subcutaneous emphysema following percutaneous tracheotomy. Poster presentation at the Annual Meeting American Academy of Otolaryngology – Head and Neck Surgery Washington, D.C. September 24-27, 2000. 7) Unilateral supraglottic edema and vocal cord paralysis following prolonged laryngeal mask airway. Poster presentation at the Annual Meeting American Academy of Otolaryngology – Head and Neck Surgery Washington, D.C. September 24-27, 2000. 8) Scientific poster making using Adobe Pagemaker. Course instructor at the Annual Meeting American Academy of Otolaryngology – Head and Neck Surgery Denver, CO September 11, 2001. 9) Steroid Treatments Restore Stria Vascularis Capillary Size in MRL/MpJ-Faslpr Autoimmune Mice. Poster presentation at ARO Mid-winter meeting, St. Petersburg, FL, January 27-30, 2002. 10) An analysis of time and staff utilization for open versus percutaneous tracheostomies. Presented at Triologic Society Western Section meeting, February 1-3, 2002. 11) Hearing Preservation after transcrusal petrosal craniotomy. Presented At Triologic Society Annual Meeting, Boca Raton, FL May 13, 2002 12) Preoperative facial muscle imaging predicts final facial nerve function after facial nerve grafting. Presented at American Society of Neuroradiology 40th Annual Meeting, Vancouver, B.C., Canada May 16, 2002. 13) Preoperative Appearance of Facial Muscles on MR Predicts Final Facial Function After Acoustic Neuroma Surgery. Presented at American Neurotology Society Spring Meeting, Nashville TN, May 3, 2003. 14) Follow-up MR Appearance of Facial Muscles Correlates With Facial Function After Acoustic Neuroma Surgery. Presented at Eastern Section Meeting of the Triological Society, January 25, 2004, New York, NY 15) Does perineural invasion of a resected facial nerve affect function after facial nerve grafting? Presented at Western Section Meeting of the Triological Society, February 1, 2004, Scottsdale, AZ 16) Surgical Management of Meniere’s Disease in the Era of Gentamicin. Presented at Triological Society Annual Meeting, Phoenix, AZ, May 3, 2004 17) Differential Diagnosis of Vestibular Disorders – Demystifying Dizziness. Presented at Baptist Hospital Center for Medical Education Evaluation and Management of Neurological Problems for the Primary Care Physician. Nashville, TN May 22, 2004. 18) Management of hearing loss: Bedford Community Hospital CME Lunch, Shelbyville, TN July 29, 2004. 19) Lateral Skull Base Malignancies. Presented at 6th International Conference on Head and Neck Cancer, Washington D.C., 8/7-8/11 2004. Publications 1) Kaylie, D.M. Hypoglossal nucleus degeneration in amyotrophic lateral sclerosis. Master’s thesis (unpublished), Medical College of Virginia, 1993. 2) DiNardo L.J., Kaylie D.M., Isaacson J. Current treatment practices for early laryngeal carcinoma. Otolaryngology-Head and Neck Surgery. 1999; 112:30-37. 3) Kaylie D.M., Stevens K.R. Jr., Kang M.Y., Cohen J.I., Wax M.K., Andersen P.E. External beam radiation followed by planned neck dissection and brachytherapy for base of tongue squamous cell carcinoma. Laryngoscope. 2000; 1633-36. 4) Kaylie D.M., Gilbert E., Horgan M.J., Delashaw J.B., McMenomey S.O. Acoustic neuroma outcomes. Otology and Neurotology 2001; 22:686-9. 5) Kaylie D.M., Kempton J.B., Hefeneider S.H., Siess D.B, Vedder C.T., Merkens L.S., Trune D.R. Decreased cohclear DNA receptor staining in MRL.MpJ-Faslpr autoimmune hearing loss mice. Laryngoscope 2001;111:1275-80. 6) Kaylie D.M., Horgan M.J., Delashaw J.B., McMenomey S.O. A meta-analysis comparing outcomes of microsurgery and gamma knife radiosurgery. Laryngoscope. 2000; 110:1850-56. 7) Kaylie D.M., Wax M.K. Massive subcutaneous emphysema following percutaneous tracheostomy. American Journal of Otolaryngology. 2002; 23:5. 300-2. 8) Kaylie D.M., Wax M.K. Unilateral supraglottic edema following use of a laryngeal mask airway. Otolaryngology - Head and Neck Surgery. 2002; 126(5): 583-4. 9) Kaylie D.M., Wax M.K., Weissman J.L. Preoperative facial muscle imaging predicts final facial nerve function after facial nerve grafting. American Journal of Neuroradiology. 24(3):326-30, 2003 Mar. 10) Kaylie DM. McMenomey SO. Microsurgery vs. gamma knife radiosurgery for the treatment of vestibular schwannomas Archives of Otolaryngology -- Head & Neck Surgery. 129(8):903-6, 2003 Aug. 11) Kaylie D.M., Horgan M.J., Hsu F.P.K., Delashaw J.B., McMenomey S.O. The transcrusal approach to the petroclival region with hearing preservation. Otology & Neurotology. 2004 July. 25(4):594-598, 12) Kaylie D.M., Andersen P.E., Wax M.K. An analysis of time and staff utilization for open versus percutaneous tracheostomies. Otolaryngology – Head and Neck Surgery. 2003; 128:1:109-113. 13) Kaylie D.M., Jackson C.G., Aulino J.M., Gardner E.K., Weissman J.L., Preoperative appearance of facial muscles on MR predicts final facial function after acoustic neuroma surgery. Otology & Neurotology. July 2004. 25(4): 622-625. 14) Gardner E.K., Jackson C.G., Kaylie D.M., Results with titanium ossicular reconstruction prostheses. Laryngoscope. 114(1): 65-70, Jan. 2004. 15) Kaylie D.M., Jackson C.G., Aulino J.M., Gardner E.K., Weissman J.L., Postoperative appearance of facial muscles correlates with facial function after acoustic neuroma surgery. Submitted to Otolaryngology – Head and Neck Surgery 16) Kaylie D.M., Jackson C.G., Gardner E.K., Phosphaturic mesenchymal cell tumor of the temporal bone. Submitted Otolaryngology – Head and Neck Surgery. 17) Gardner E.K., Jackson C.G., Kaylie D.M., Results of revision chronic ear surgery. Submitted to Laryngoscope. 18) Kaylie D.M., Jackson C.G., Gardner E.K., Surgical management of Meniere’s disease in the age of gentamycin perfusion. In Submission: Otolaryngology – Head and Neck Surgery 19) Jackson C.G., Kaylie D.M., Coppit G., Garner E.K., Glomus jugulare tumors with intracranial extension. Neurosurgical Focus 17(3): B7, 2004. 20) Wooton, CM, Kaylie D.M., Warren F.M., Jackson C.G., Management of brain herniation and CSF leak in revision chronic ear surgery. Submitted to Laryngoscope 21) Kaylie D.M., Warren F.M., Jackson C.G., Neurotologic management of intracranial epidermoid tumors. Submitted to Laryngoscope. Interests and Activities Skiing, music, hiking and camping Teaching assistant for gross anatomy for medical students for two years as a graduate student and two years as a resident. Database design for management of the skull base clinic and cochlear implant program.