ENERGY IN FOOD Digestive System Enzymes/pH 1 Food and Energy • Organisms must obtain energy to carry out life processes • Amount of energy in food is measured in Calories • Food also contains the raw materials (nutrients) used to build/ repair body tissues • Nutrients supplied by food: Water Carbohydrates Lipids (fats) Proteins Vitamins Minerals 2 Function of the Digestive System • Breaks up food physically & chemically • Stores food for a short time • Absorbs digested foods and passes them into the circulatory system • Stores and eliminates undigested food from the body • Types of Digestion 1. Mechanical: The physical breakdown of food by non-enzyme means 2. Chemical: The use of enzymes to breakdown food 3 Function of the Digestive System, cont. • Consumers must be able to break down food into molecules that can be absorbed and used by cells • In many multicellular organisms, this is accomplished by a digestive system 4 Enzymes and Digestion • Enzyme – specialized proteins that act as biological catalysts • Catalyst – substance that speeds up chemical reactions and remains unchanged by the reaction • All the activities of living things are controlled by chemical reactions • Without enzymes, these reactions would happen too slowly or require so much activation energy that the organism would die 5 Enzymes and Digestion, cont. • Activation energy – amount of energy needed to get a chemical reaction started • Chemical reaction – the breaking down and/or forming of new compounds 6 Enzymes… • Are: a three dimensional protein • Have: a specific area that attaches to the chemical compound undergoing change (active site) • Fit: like a puzzle piece to one type of compound (substrate) 7 Enzymes… • Need: specific pH range • Require: constant body temp (Humans – 98.6o F) high temperatures denature (change shape) of enzymes 8 Enzyme-Substrate Complex • When the enzyme binds with its substrate, changes occur in the enzyme at the active site • This alteration of the active site is called induced fit • Induced fit enhances the enzyme’s ability to break down the substrate • If the enzyme is missing or damaged, the reaction cannot happen • Example: lactose intolerance 9 Enzyme Inhibition Inhibition – keeping something from working correctly • Competitive Inhibitors: Chemicals that resemble and enzyme’s normal substrate and compete for the active site • Allosteric Inhibitors: Chemicals that do not bond to active site but to another part of enzyme; changes enzyme shape 10 Organs of the Digestive System • Digestion begins in the mouth with: 1. Mechanical - teeth & tongue chop/mix the food 2. Chemical - salivary glands add amylase to break down starches into simple sugars 11 Organs of the Digestive System, cont. • Pharynx – located at back of throat; opening for tubes that lead to 2 systems 1. Respiratory – trachea 2. Digestive – esophagus • Epiglottis – flap of tissue that covers opening to tube not being used 12 Organs of the Digestive System, cont. • After swallowing, food moves down the esophagus to the stomach • The food is moved in a one-way direction by smooth muscle contractions (peristalsis) • The Stomach: 1. Digests mechanically & chemically 2. Has pH of 2 3. Secretes enzyme pepsin (acts on proteins) 13 14 Organs of the Digestive System, cont. After ~ 2 hours the food leaves the stomach and enters The Small Intestine: • 7 meters long – 2.5 to 3 cm diameter • Most chemical digestion and absorption of nutrients occurs here • Digestion of carbs , proteins, lipids and nucleic acids 15 Organs of the Digestive System, cont. • Accessory Organs of Small Intestine: Pancreas Liver Gall Bladder 16 Organs of the Digestive System, cont. • After 4-6 hours what is left of your meal leaves your small intestine and enters The Large Intestine • ~ 1.5 meters long • 3 sections – cecum, colon and rectum • Absorbs water & salts from the undigested material • Colonies of E. coli will produce vitamin K (for blood clotting) and other compounds needed to complete digestion. • Solid waste stored in rectum & excreted through anus 17 18 Organs of the Digestive System, cont. • Lining of Small Intestine: The small intestine is folded into fingerlike projections called villi The villi are covered in even smaller projections called microvilli These structures increase the total surface area over which nutrients can be absorbed into the blood stream • The small and large intestines have an extensive supply of capillaries; this allows the digested nutrients to easily enter the circulatory system 19 20