华东师范大学校级学术报告
清松化学学术系列讲座
报告题目:
报告人介:
Kürti
报告内容：
Exploiting the Extraordinarily Versatile N-O
Bond: Rapid Synthesis of Biaryls, Carbazoles,
Primary Aromatic Amines and Aziridines
Prof . László
2010 Fall-, Tenure Track at UT Southwestern Medical Center;
2006-2010, Postdoctoral Studies, Harvard University,
Cambridge, MA;
2001-2006, Ph.D. in Organic Chemistry – University of Penns
ylvania, Philadelphia, PA;
2001 June, Masters Degree in Organic Chemistry – University of
Missouri, Columbia, MO;
1998 June, Diploma in Chemistry – Lajos Kossuth University
(now Univ. of Debrecen), Debrecen, Hungary.
The Kürti lab has been exploring several fundamentally new strategies for the
transition-metal-free direct: (i) arylation of arenes; (ii); a-arylation of ketones, esters
and amides; (iii) O-arylation of oximes; (iv) primary amination of arylboronic acids and
(v) intramolecular C(sp2)-H amination of arenes. We have also discovered, in
collaboration with the Falck (UTSW) and Ess labs (BYU), the Rh-catalyzed direct NH/N-alkyl aziridination of olefins, a transformation that eluded synthetic chemists for
decades. These methods have one thing in common: a weak N-O bond is cleaved in
order to form a stronger C-C or C-N bond. In-depth experimental and computational
studies have already identified the critical factors required for efficient alkyl-aryl, arylaryl, O-aryl and N-aryl bond-formation and led to several innovative and
environmentally benign methods for the rapid preparation of structurally diverse
arylated carbonyl compounds, functionalized biaryls as well as O- and N-heterocycles.
2014年5月30日（星期五）上午 9：15
报告时间与地点：
华东师范大学中北校区化学馆A205报告厅
主办：华东师范大学化学系
上海市绿色化学与化工过程绿色化重点实验室
资助：华东师范大学自然科学系列学术活动专项经费
上海清松药业有限公司