COLLABORATORY RESEARCH PROJECTS: MACEWAN PHYSICAL SCIENCES Dr. Samuel Mugo 1 Listen to Nature, Learn from Nature “Being ‘less bad’ is no good.” The world will not evolve past its current state of crisis by using the same thinking that created the situation. -Albert Einstein 2 Collaboratory Research Project Themes FATS and OILs Value added Green Products U of A: Dr Curtis Natural Products Profiling Bioactive, sensory, antioxidants, allelopathic compounds Dr. Njenga, Dr Mellisa Hills Novel Analytical Platforms for Environmental and Food monitoring On-site integrated sampling techniques ARDN Hormones and AntibioticsNSERC project Destroy antibiotics in cattle manure: use it as fertilizer Dr. Withey, Highmark FATS and OILs Oils and fats: Most important renewable materials. Exploit carboxylate chemistry Transformations (natural catalysts) Green Products Wax esters, Structured lipids, Biodiesel, Natural Products Profiling Bioactive, sensory, antioxidants, allelopathic compounds Natural Products: Antioxidants -If you keep food for a long time on shelf they go bad: Preserve TIME Natural antioxidants: Synthetic antioxidants: Quercetin-3-glucoside Safety (Carcinogenic) Concerns? No harmful physiological effects Not Fat-soluble (mainly hydrophilic) Economical 6 Antioxidants (polyphenolics) From Herbal Plants More effective than BHT and BHA Rosemary (Rosmarinus Officinalis L.): Common spice widely used in food processing Obtained by extraction with ethanol/methanol fraction 7 Yanishlineva et al. Eur. J. Lipid. Technol. 108(2006): 776 Antioxidants (polyphenolics) From Herbal Plants Oregano (Oreganum Vulgare L.) antimicrobial and antioxidant properties 8 Yanishlineva et al. Eur. J. Lipid. Technol. 108(2006): 776 Herbal Plants and Spices of Interest Plants from: Strychnos heningsii (muteta) Cure and Prophylaxis of arthritis Botany Depart: JKUAT (KENYA) Ixora scheffleri K.Schum Compounds to look for with antioxidant activity: flavonols, flavonoids, isoflavones, diterpenes and phenolic acids Clausena anisata Tamarindus indica. (Give herbal preparations sweet smell) 9 Concomitant study of the secondary Metabolites Our research Figure 1. Myrianthus Hostii, an East African Herbal Plant Often taken as a concoction for myriad remedies Seeds used to treat boils, bark decoction for lowering sugar level Used in the management of flu and cold; antimicrobial Piper capense Characterization of active compounds makes their use safer! 10 Natural Products Aloe Vera allelopathic compounds Bioactive and sensory compounds Novel Analytical Platforms for Environmental and Food monitoring MUGO-Rural Alberta Water Quality Monitoring: concept map In House Developed microbore microextractors Drinking water from tap Onsite microbore microextractor Different types of polymer in different morphologies entrained in the microbore to extract the contaminant Online couple to GC-MS (trihalomethanes, volatile compounds) Online couple to ICP or AAS (heavy metal analysis) Elute to LC-MS (polyromatic hydrocarbons, EDCs) CHEMOMETRICs (DR. KAREN BURO Using statistical tools to quickly interpret complex data quickly acquired by Fourier Transform Spectroscopic Methods: FTIR and RAMAN Adulteration in Foods Case of Melamine tainted Milk, cat food etc. Nitrate tainted milk Trans Fats in Cookies Olive oil spiked with Canola oil NSERC-funded research on hormones and antibiotics Project: Development of a novel, practical approach for the detection, trac destruction of antibiotics and hormones in animal biowaste Collaborative project with Highmark Renewables Research, and part of the bioWaste to Energy for Canada Integration Initiative (BECii) Currently funded by a two-year $200,000 NSERC CCI grant Method development taking place entirely at the MacEwan campus, utilizin start-of-art instrumentation and dedicated research space acquired as par new baccalaureate degree programs Project involves two MacEwan faculty members, one post-doctoral researc associate, and employs four undergraduate students as research assistan year. Equipment Infrastructure GC-MS LC LCQ Fleet ion trap MSn Dual-laser Raman spectrometer (3 cm-1) with optical microscope We service clients off-campus for a reasonable fee FT-IR Atomic absorption spectrometry 400 MHz NMR spectrometer iCAP (inductively coupled plasma spectroscop We service clients off-campus for a reasonable fee Challenges/opportunities Students Training Opportunity: Karl ayton, Alex Cerezo, Samuel Langman, Linh Tran, Jennifer, Lauren, Patrick, Merrill Singleton etc. We are collaboration crazy! It is the way to go Money- Getting access to money from other funding agencies (NSERC, ARDN, Canola growers Association, CIDA, CHIR, AACTI, AIF etc.