Hosted By Mrs. Lori Schalles Structure DNA DNA Replication RNA transcription 100 100 100 100 200 200 200 200 300 300 300 300 400 400 400 400 500 500 500 500 Final Jeopardy 1 Final jeopardy 2 TranslationProtein synthesis QUESTION: Who are the American biologists who made the double helical model of the DNA molecule in the 1950s & won a Nobel Prize. Also, Maurice Williams & Rosalind Franklin worked on this model. ANSWER: James Watson & Francis Crick Row 1, Col 1 QUESTION: What are enzymes that separate DNA strands during replication by breaking hydrogen bonds between complementary nitrogenous bases. ANSWER: Helicase 1,2 QUESTION: What is the synthesis of an RNA molecule from information in DNA? (Its the process by which the genetic instructions in a specific gene are “transcribed” or rewritten as an RNA molecule.) ANSWER: Transcription 1,3 QUESTION: What is the process of making proteins from the combined efforts of mRNA, tRNA & rRNA called? ANSWER:Translation. 1,4 QUESTION: What are the repeating subunits that make up a DNA molecule & consist of 3 parts: a 5 carbon sugar, a phosphate group & a nitrogenous base. ANSWER: Nucleotide 2,1 QUESTION: What is the 2 separated strands of the DNA molecule which serve as templates for making a DNA copy or an RNA molecule. ANSWER: Replication fork 2,2 QUESTION: What is the enzyme that catalyzes the formation of RNA on a DNA template. Adds free nucleotides that are complementary to DNA nucleotides & results in an RNA chain? ANSWER: RNA polymerase 2,3 QUESTION: What is the series of steps in translation where amino acids are added to the growing protein chain called? (Where codons on tRNA bringing each new amino acid to the ribosome as it reads mRNA. & Each amino acid is bonded by a covalent peptide bond.) ANSWER: Elongation. 2,4 QUESTION: What are the types of bonds between complementary nitrogenous bases that can be easily broken (zipped & unzipped) for DNA replication, RNA transcription & translation into proteins. ANSWER: Hydrogen bonds. 3,1 QUESTION: What is a change in the nucleotide sequence in a DNA molecule? ANSWER: Mutation 3,2 QUESTION: What is the 3 nucleotide sequence in mRNA that encodes an amino acid or signifies a start or stop signal called? (when 3 letters = 1 amino acid) ANSWER: codon 3,3 QUESTION: What is the order of the nitrogenous bases (A ,T, G,C) (Adenine, Guanine, Thymine, Cytosine) on a chain of DNA called? ANSWER: The DNA Base Sequence 3,4 QUESTION: What is it called when the base Adenine always pairs with Thymine & Guanine always pairs with Cytosine (AT, GC) ANSWER: Complementary Base Pairing Rule 4,1 QUESTION: What is the enzyme in DNA replication that adds individual nucleotides to the unzipped template side of a DNA molecule? (It results in 2 identical DNA strands.) ANSWER: DNA polymerase 4,2 QUESTION: What is the corresponding group of 3 nitrogenous bases on a tRNA molecule (that, along with mRNA’s codon- will build a protein at rRNA) ? ANSWER: Anticodon 4,3 QUESTION: What is the set of rules that relates how a particular sequence of nitrogenous bases corresponds to a particular amino acid called? (How the groups of 3 “letters” (combos of A,U,G & C) on DNA make mRNA & code for a specific amino acid) ANSWER: the genetic code 4,4 QUESTION: Who is the scientist who in 1928 showed the concept of “transformation” – hereditary material passed from 1 bacterial cell to another. (The surprising result of his test was that the heat killed non virulent strains killed mice.) ANSWER: Frederick Griffith 5,1 QUESTION: What is the concept of DNA replication in which one of the strands in each new DNA molecule is “conserved” or kept intact from the original DNA molecule that was copied & one side is a new strand of nucleotides? ANSWER: The semi- conservative model of DNA replication 5,2 QUESTION: What is the specific nucleotide sequence that tells the enzyme RNA polymerase where to bind to a DNA sequence and begin making an RNA polymer? ANSWER: Promoter. 5,3 QUESTION: What is the complete sequence of nucleotides in human DNA called? (There are 3.2 billion base pairs decoded.) ANSWER: The Human Genome. 5,4 FINAL JEOPARDY QUESTION: What is the flow of information in the genetic code. ANSWER: DNA – RNA- Protein QUESTION: What is the sheep who was the first cloned mammal in 1997 in England. ANSWER: Dolly the Sheep