Gene Pool - all alleles of all individuals in a population species: interbreed & produce fertile offspring a shared gene pool Different The Gene Pool species do NOT exchange genes by interbreeding Different species that interbreed often produce sterile or less viable offspring e.g. Mule - Populations A group of the same species living in an area No two individuals are exactly alike (variations) More Fit individuals survive & pass on their traits Adaptation Process when a population becomes better suited to its environment finches had to evolve in order to FIT into environment Populations living in different places become increasingly different as each becomes adapted to its own environment Process Speciation of species formation One species may split into 2 or more species A species may evolve into a new species Requires very long periods of time At Shambala Preserve, not far from Hollywood, Patrick the liger looks ready for his close-up. The preserve, run by The Birds star Tippi Hedren, bills itself as "a haven for endangered exotic big cats."Though few ligers exist, they may not exactly be endangered, since they are not thought to exist in the wild. It's a matter of geography and genetics: Lions generally live in Africa, tigers in Asia. Plus, interspecies breeding tends to result in "diminished fitness of the offspring," according to Ronald Tilson, director of conservation at the Minnesota Zoo in Apple Valley. • Read "Ligers Make Dynamite Leap Into Limelight" •—Photograph © by Bill Dow/Shambala Preserve Divergent evolution - Related populations become less similar as they respond to different environments Accumulate differences Coevolution – process when 2+ species change in response to each other E.g. plants & birds Homologous structures – feature that share a common ancestor different function, similar structure E.g. whale flipper & human arm Analogous structure – feature that has same function with similar structure But very different internal anatomy & embryological development E.g. bird wing and moth wing Vestigial structures – structure that no longer serves an important function E.g. tail bone, wisdom teeth, appendix Convergent evolution occurs when the environment selects similar phenotypes but ancestral type is very different E.g. sharks & porpoises (fish & mammal) Causes of variation Influenced by environment & heredity Variations in genotype by: Mutation Recombination of genes during meiosis Random fusion of gametes Changes in equilibrium due to… Immigration – movement INTO a population Emigration – movement OUT of a population Genetic drift change in gene pool of small population due to lack of contributing organism e.g. Failure to produce offspring or too many offspring significant effect of random events or chance 4 types of natural selection Stabilizing selection – individuals with average traits – fittest Directional selection – environment ‘directs’ individuals with extreme trait to be fittest E.g. anteater tongue Disruptive selection – individuals with either extreme are fittest – it ‘disrupts’ the norm E.g. lizard size E.g. limpet shell color Sexual selection – female attraction to male E.g. peacock Isolating mechanisms Geographic isolation – physical separation of members of population MOST COMMON way for new species to form E.g. canyon, climate Reproductive isolation – barriers to successful breeding between groups in population E.g. sterile offspring, death before birth, mating times Rate of speciation Gradual formation? gradualism punctuated equilibrium – sudden shift in form Takes a few thousand years instead of a few million Modern Synthesis Theory Combines Darwinian selection and Mendelian inheritance Population genetics study of genetic variation within a population Emphasis on quantitative characters Modern Evolutionary Thought Modern Synthesis Theory (1940s) – comprehensive theory of evolution Fisher & Wright Previously many did not accept that Darwin’s theory of natural selection could drive evolution S. Wright A. Fisher Modern Synthesis Theory on evolution GENES are responsible for the inheritance of characteristics POPULATIONS, not individuals, evolve due to natural selection & genetic drift SPECIATION due to the gradual accumulation of small genetic changes Changes Microevolution occur in gene pools due to mutation, natural selection, genetic drift, etc. Gene pool changes cause more VARIATION in individuals in the population E.g.: Bacteria becoming unaffected by antibiotics (resistant) Gene Pools If all members of a population are homozygous for a particular allele, then the allele is fixed in the gene pool. The Hardy-Weinberg Theorem Used to describe a non-evolving population. Shuffling of alleles by meiosis and random fertilization have no effect on the overall gene pool. Natural populations are NOT expected to actually be in Hardy-Weinberg equilibrium. Assumptions of the H-W Theorem 1. Large population size - small populations can have chance fluctuations in allele frequencies (e.g., fire, storm). 2. No migration - immigrants can change the frequency of an allele by bringing in new alleles to a population. 3. No net mutations - if alleles change from one to another, this will change the frequency of those alleles Assumptions of the H-W Theorem 3. Random mating - if certain traits are more desirable, then individuals with those traits will be selected and this will not allow for random mixing of alleles. 4. No natural selection - if some individuals survive and reproduce at a higher rate than others, then their offspring will carry those genes and the frequency will change for the next generation. Hardy-Weinberg Equilibrium The gene pool of a non-evolving population remains constant over multiple generations; i.e., the allele frequency does not change over generations of time. The Hardy-Weinberg Equation: 1.0 = P2 + 2Pq + q2 where P2 = frequency of PP genotype 2Pq = frequency of Pq plus qP genotype q2 = frequency of qq genotype 1.0 = P2 + 2Pq + q2 P q P PP Pq q Pq qq 1 : 2 : 1 Directional selection 29 Diversifying selection favors extreme over intermediate phenotypes. - Occurs when environmental change favors an extreme phenotype. Stabilizing selection favors intermediate over extreme phenotypes. - Reduces variation and maintains the current average. - Example = human birth weights. 30 31 Natural selection maintains sexual reproduction -Sex generates genetic variation during meiosis and fertilization. -Generation-to-generation variation may be of greatest importance to the continuation of sexual reproduction. -Disadvantages to using sexual reproduction: Asexual reproduction produces many more offspring. -The variation produced during meiosis greatly outweighs this disadvantage, so sexual reproduction is here to stay. 32 Sexual selection leads to differences between sexes a. Sexual dimorphism is the difference in appearance between males and females of a species. -Intrasexual selection is the direct competition between members of the same sex for mates of the opposite sex. -This gives rise to males most often having secondary sexual equipment such as antlers that are used in competing for females. -In intersexual selection (mate choice), one sex is choosy when selecting a mate of the opposite sex. -This gives rise to often amazingly sophisticated secondary sexual characteristics; e.g., peacock feathers. 33 34 Five Agents of Evolutionary Change Mutation Mutation rates are generally so low they have little effect on Hardy-Weinberg proportions of common alleles. ultimate source of genetic variation Gene flow movement of alleles from one population to another tend to homogenize allele frequencies 35 Five Agents of Evolutionary Change Nonrandom mating assortative mating - phenotypically similar individuals mate Causes frequencies of particular genotypes to differ from those predicted by Hardy-Weinberg. 36 Five Agents of Evolutionary Genetic drift – statistical accidents. Change Frequencies of particular alleles may change by chance alone. important in small populations founder effect - few individuals found new population (small allelic pool) bottleneck effect - drastic reduction in population, and gene pool size 37 Forms of Selection Disruptive selection Directional selection Selection eliminates intermediate types. Selection eliminates one extreme from a phenotypic array. Stabilizing selection Selection acts to eliminate both extremes from an array of phenotypes. 38 Kinds of Selection 39 Selection on Color in Guppies Guppies are found in small northeastern streams in South America and in nearby mountainous streams in Trinidad. Due to dispersal barriers, guppies can be found in pools below waterfalls with high predation risk, or pools above waterfalls with low predation risk. 40 Evolution of Coloration in Guppies 41 Selection on Color in Guppies High predation environment - Males exhibit drab coloration and tend to be relatively small and reproduce at a younger age. Low predation environment - Males display bright coloration, a larger number of spots, and tend to be more successful at defending territories. In the absence of predators, larger, more 42 Why is genetic variation important? variation global warming survival EXTINCTION!! no variation 43 Forces that affect allele freq. 1. 2. 3. 4. Mutation Migration Selection Random (genetic) drift Selection and migration most important for livestock breeders. 44