0. Courses Other Information 1. The Molecules of Life 2. The Origin of Life 3. The Cell – an Introduction Department of Medical Biology Our courses Compulsory course: Elective courses: Cell Biology and Molecular Genetics Basics of Molecular Biology Frontiers of Molecular Biology Genetic Analysis Medical Molecular Biology and Genomics Developmental Genetics Pre-Med Cell Biology and Molecular Genetics Lecturers János Szabad Dóra Tombácz Zsolt Boldogkői Ernő Duda István Belecz Cell Biology and Molecular Genetics - 2 hours/week, 4 credit points - Time: every Tuesday 11:00 – 12:30 - Place: Ophthalmology Clinic (here) Curriculum: 1. PowerPoint pictures + supplementary material (Word documents) – from our homepage 2. Textbook: LIFE (9th Edition) Cell Biology and Molecular Genetics Ist Semester 1. Origin of Life Basics of Cell Biology 2. The DNA 3. RNAs Proteins 4. Cell Cycle, Cytoskeleton Cytogenetics 5. Transport Processes 6. Human Genome 7. Inheritance 8. Genetic Regulation Epigenetics 10. Evolution 9. Genes and traits 11. Viruses 12. Bacteria 13. Techniques of Molecular and Cell Biology 14. Selected Topics in Biology 2nd Semester 15. Basics of Cell Communication 16. Complex Cell Signaling Pathways* 17. Neural Communication 18. Genetic Regulation of Development 19. Immunogenetics 20. Genes and Behavior 21. Biotechnology Recombinant Gene Technology 22. Frontiers of Molecular Biology 23. Molecular Biology of Cancer 24. Chromosomal Disorders 25. Molecular Biology of Diseases 26. Molecular Biology of Brain and Mental Disorders 27. Molecular – and Stem Cell Therapy 28. Medical Genomics Evolution Optional topic instead of Evolution: Cellular Energetics Cell Biology and Molecular Genetics Test questions on each lecture: bonus points! Cheating will be punished! Cell Biology and Molecular Genetics Curriculum Three levels (1) Basic requirements maximal grade: 3 (2) Extra requirements: grades from 1 to 5 (3) Facultative requirements: will be not asked at the MTOs and the exams Cell Biology and Molecular Genetics MTOs 1st MTO: Oct 17 – 18 1-6 lectures + 1-2 practices 2nd MTO: Nov 28 - 29 7-12 lectures + 4-6 practices Retake MTO: Dec 9 Super Monday ----------------------------------------------------------------------------------- EXAM: Written, but oral is also possible: Write an email for the oral exam: tombacz.dora@med.u-szeged.hu QUESTIONS max. 100 points Consultations: Essay questions: From basic requirements 3 questions = 60 points From Extra requirements 2 questions = 20 points Definitions : From basic requirements 5 questions: 5x2 p = 10 points From Extra requirements 5 questions: 5x2 p = 10 points (1) The weeks before the MTOs (2) On Super Monday (December 9.) morning Cell Biology and Molecular Genetics Points and grades: MTO: 0 - 30p: 30,5 – 55p: 55,5 – 70p: 70,5 – 85p: 85,5-100p: EXAM: 1 2 3 4 5 0 - 45 p: 45,5 – 63p: 63,5 – 75p: 75,5 – 90p: 90,5-100p: 1 2 3 4 5 Cell Biology and Molecular Genetics Rewards: (bonus points and other premiums) (1) attendance of the lectures (2) attention in the lectures (3)Attendance and attention at the practices (4) activity in practices, seminars and lectures (5) good performance at the MTOs (6)Others: attendance in - Basics in Molecular Biology course - some Frontiers of Molecular Biology lectures Penalty: (1) failed the MTO(s) (2) non-attendance of practices The MTO grades can be calculated to the exam grade Cell Biology and Molecular Genetics practice 4 hrs/2 weeks, The first parts os the practices are seminars (2 groups are together at the larger practice hall!) Tests at the first 10 minutes of the practices: 5 questions (simple choice: 2-2 questions from the former two lectures and one question from the former practice) – Bonus points for the corrects answers Place: Department of Medical Biology Absences from the practices: 1 absence: nothing to do 2 absences: Report about the missing practices 3 absences : additional practical question on the exam 4-7 absences : no signiture in the index book Seprényi György Cell Biology and Molecular Genetics practice 1st Semester 2nd Semester 1. Handling of technical instruments 1. PCR 2. Microscopy 2. Molecular cloning 3. Consultation 3. Consultation 4. Lac operon + DNA and RNA isolation 4. Detection of proteins 5. Exercises on Mendelian genetics 5. Clinical diagnostics 6. Consultation 6. Consultation 7. Separation techniques 7. Genomics Basics of molecular biology - 1hr/week, elective course - For students with week background in biology - Exam – written Date: Site: every Friday, 12:00-12:45 Dermatology clinic Zsolt Boldogkői Frontiers in molecular biology 2 hrs/week, elective course - The most interesting topics of biology - Exam: essay or regular exam (written or oral) Date: every Monday, 18:00-19:45 Site: Ophthalmology clinic Zsolt Genetic Analysis (Molecular Medicine) Zsolt Boldogkői - On - 2 hrs/2 weeks, elective course Date: Every 2nd Monday, 18:00 – 19:40 Site: decided later the interface of medicine and - Invited lecturers - Exam: essay or regular exam molecular biology István Belecz Developmental genetics János Szaba - 1 hr/week Medical Molecular Biology and Genomics - 1hr/week at the 1st semester, for 4th and 5th-year students Zsolt Boldogkői date: every 2nd Wednesday, 18:00-19:45 place: Educational Center (Dóm Square 13, lecture room 49. Pre-Med Course Zsolt Boldogkői -1x2h/week lecture; 2x2 h/week seminar, in both semesters! time: xxx place: Lecture: xxxx; Seminar: xxx István Belecz Interactive Institute http://www3.szote.u-szeged.hu/mdbio/indexeng.html http://www3.szote.u-szeged.hu/mdbio/indexeng.html Passwords for the courses LECTURE PASSWORD Cell Biology and Molecular Genetics (lecture): Zsolt Basics of Cell Biology: Dora Cell Biology and Molecular Genetics (practice): Gyorgy Frontiers of Molecular Biology: Erno Developmental Genetics: Janos Genetic Analysis (Molecular Medicine): Istvan Medical Molecular Biology and Genomics Belep Pre-Med Premed