Mutation and genetic recombination

MUTATION AND GENETIC
RECOMBINATION
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How do they
increase
genetic
variation?
FLORIDA STANDARD
 SC.912.L.15.15
 Describe how mutation and genetic recombination increase genetic
variation.
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OBJECTIVE
 By the end of this lesson you will be able to:
 --Describe how mutation and genetic recombination occur
 --Explain how mutations and genetic recombination increase genetic
diversity in a population
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REVIEW
 What is the definition of a mutation?
 A change in the structure of genes or chromosomes of an organism.
(nucleotides are altered)
 Is a mutation natural or man made?
 A mutation is natural
 What examples of mutations can you give? (think the
direction of nucleotides)
 Substitution
 Addition
GENETIC RECOMBINATION
 Definition: The exchange of genetic information in order to
increase the genetic diversity of the population.
 This is seen in nature and can be man made
 Man made genetic recombination is also call genetic engineering
 How is genetic recombination used in our society?
Used for vaccines
Food
Bacteria
BACTERIAL GENETIC RECOMBINATION
 Bacterial DNA can mutate and “trade” DNA with other
bacteria.
 This “trade” can be beneficial and have negative ef fects.
 White Board: What is one benefit and one negative ef fect of
bacterial genetic recombination?
 One benefit is vaccines:
 One negative is resistance to antibiotics
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RECOMBINATION AND FOOD
 A big topic in our society at the moment is GMO ’s or
genetically modified organisms. Genetic engineering
simulates genetic recombination.
 Food has been altered for many reasons a few of them are:
 Pesticide resistant
 Hinder bugs
 Bigger food
 Many stores and people are looking for organic foods that
have not been modified or exposed to pesticides.
 Examples of GMO’s
 Rice
 Corn
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WHITE BOARD QUESTION
 Describe the dif ference between mutations and genetic
recombination:
 A. A mutation is man made while genetic recombination is natural
 B. Both are man made occurrences
 C. Mutations are changes in nucleotides while genetic recombination
is the transfer of genetic information
 D. Genetic recombination is only seen in bacteria and mutations are
only seen in humans
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WHITE BOARD QUESTION
 A gene from a large red apple is inserted in the the DNA of a
small yellow apple. The result is a medium sized red and
yellow apple. This is an example of:




A. Mutation
B. Bacteria
C. Mad scientists
D. Genetic recombination
 -What would be an example of a mutation?
 Many examples can be explain: An example would be a change in one
gene such as the BRCA -1 (breast cancer gene) which could give a greater
chance for the cancer.
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THE FUN STUFF!
 Genetic Engineering is a
simulation of recombination in animals
 A few examples:
 Glow in the dark monkeys
 Double muscled animals
 Spider Goats
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WHITE BOARD QUESTION
How do mutations and genetic recombination increase genetic
diversity?
Both mutations and genetic recombination have changes in the
DNA that can be pasted onto of fspring. The of fspring could
then pass the changes onto their of fspring. This gives more
variety in a population.
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RECAP
 Mutations have altered nucleotide sequences
 Genetic recombination is the transfer of DNA either in nature
or man made
 Genetic recombination occurs in bacteria and it can help with
vaccines. It can also be harmful with antibiotic resistance.
 GMO’s are examples of simulated recombination and are
found everywhere!
 Genetic diversity is increased do to the changes in this
modified DNA and can be passed onto of fspring
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COPYRIGHT AND CREDIT
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Pictures:
http://www.ask4biology.com/wp content/uploads/2013/02/Gene-Mutation.jpg
 www.belgiumblue/wp/upload/2001 .jpg
http://site.motifolio.com/images/The -Ti-plasmid-as-a-vectorin-plant-genetic-engineering-1021160.png
http://blogs.sundaymercury.net/weirdscience/monkey_x600.jp
g
http://ts4.mm.bing.net/th?id=HN.608041535371608322&pid
=1 .7
Marisa Colyer 2014
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