Blood Types
The Genetics of Blood Type
Codominance
• Both alleles are Dominant.
• Neither allele for a trait is recessive.
• They both express themselves in the
phenotype.
A
B
• Genotype labels are: I I
• I = blood: A=type A coded protien
B=type B coded protien
The Genetics of Blood Type
Phenotype
Genotype
The Genetics of Blood Type
Phenotype
A
Genotype
The Genetics of Blood Type
Phenotype
A
B
Genotype
The Genetics of Blood Type
Phenotype
A
B
AB
Genotype
The Genetics of Blood Type
Phenotype
A
(I A)
B
B
(I )
AB
O
(recessive)= i
Genotype
The Genetics of Blood Type
Phenotype
A+
A-
Genotype
( + = Rh factor, protein on cell, Antigen.
Will be recognized by immune system
as part of body. )
( - = no Rh factor antigen. If body comes in
contact with +, it won’t recognize it as part of
the body and will reject it )
B
(
AB
O
+
is dominant over
-)
The Genetics of Blood Type
Donor/Recipient?
The Genetics of Blood Type
Phenotype
A+
AB+
BAB+
ABO+
O-
Genotype
If Immune system doesn’t recognize a protein,
A or B, it’ll reject it.
A -Rh will not recognize +Rh and reject it.
Can receive: B+B-O+O- Will reject A+-AB+Can receive: B-O-
Will reject A+-B+AB+-O+
Can receive: ALL blood types
Can receive: All – types Will reject all + types
Can receive: O+O-
Will reject all others
Can receive: O-
Will reject all others
The Genetics of Blood Type
Phenotype
A+
AA++
AB+
BAB+
ABO+
O-
Genotype
The Genetics of Blood Type
Phenotype
Genotype
A+
AA++, AO++
AB+
BAB+
ABO+
O-
The Genetics of Blood Type
Phenotype
Genotype
A+
AA++, AO++, AA+AB+
BAB+
ABO+
O-
The Genetics of Blood Type
Phenotype
Genotype
A+
AA++, AO++, AA+-, AO+AB+
BAB+
ABO+
O-
The Genetics of Blood Type
Phenotype
A+
AB+
BAB+
ABO+
O-
Genotype
AA++, AO++, AA+-, AO+AA--, AO-BB++, BO++, BB+-, BO+BB--, BO-AB++, AB+AB-OO++, OO+OO--
The Genetics of Blood Type
How can we predict Blood Type inheritance?
Using a Punnett square!
Let’s look at possible blood types of the children
of a couple whose blood types are AB- and O-.
The Genetics of Blood Type
First we need to determine their genotypes.
Looking at our chart, the genotype for AB- is AB-and the genotype for O- is OO--.
We need to FOIL and then draw a Punnett square.
From one parent we can get A- or BFrom the other we can only get O-.
The Genetics of Blood Type
O-
A-
AO--
B-
BO--
The Genetics of Blood Type
O-
A-
AO--
B-
BO--
The Genetics of Blood Type
O-
A-
AO--
B-
BO--
The Genetics of Blood Type
O-
A-
AO--
B-
BO--
The Genetics of Blood Type
O-
A-
AO--
B-
BO--
The Genetics of Blood Type
O-
A-
AO--
B-
BO--
The Genetics of Blood Type
O-
Phenotype
A-
AO--
A-
B-
BO--
B-
The Genetics of Blood Type
Your homework:
Blood Types Worksheet