Objective 9: Explain why cells must be small in order to survive and function properly. 1.Nucleus/DNA DNA in the nucleus controls cell activities The nucleus can only control a limited amount of active cytoplasm—so the cell can’t get too big 2. Size of cell membrane Cells obtain nutrients and rid themselves of waste through the cell membrane As cell increases in size, the need for materials as well as the waste production increases—so surface area of the cell membrane must increase in order to bring in enough materials and rid the cell of its wastes. 2. Size of cell membrane As the cell gets larger, though, the surface area (of the cell membranes) to volume (of the cell) ratio gets smaller. So…if a cell is small, it has a better chance of exchanging enough materials to support its cytoplasm. Objective 8: Describe how cell division benefits survival of organisms. Multicellular organisms grow (get bigger/increase in size) because of an increase in the number of cells In multicelluar organisms, injuries can be mended by making new cells. In order to maintain certain tissues, organisms make new cells New organisms are made by cell division Maintain a high surface area to volume ratio for material exchange Objective 3: Describe DNA replication (When, Where, How, Why) 1. 2. When does DNA replicate? before the cell divides Where does DNA replicate? nucleus 3. How does DNA replicate? 1. Enzymes unzip DNA strand (DNA polymerase) 2. New nitrogen bases pair up with each exposed side 3. Result is 2 identical DNA molecules (each new DNA molecule has one old strand and one new strand) Why does DNA replicate? 4. ◦ ◦ to make 2 identical molecules of DNA to have DNA in each of the new cells Objective 4: Describe the major events in the cell cycle. Objective 5: Compare the relative amount of time for interphase and cell division to occur. Objective 6: Order and describe the four major events of mitosis. Objective 7: Describe the outcome of mitotic cell division. 1. Interphase ◦ Cells spend most of their time here ◦ Normal cell activities occur Cell grows Cell makes new organelles Protein synthesis DNA replicates *Once a cell copies its DNA, it usually completes the rest of the cell cycle. 2. Cell Division a. Nuclear Division (mitosis) b. Cytoplasmic Division (cytokinesis) http://cellsalive.com/mitosis.htm