Curriculum Vitae Gianni Pedrizzetti PhD Full Professor of Fluid Mechanics (Professore Ordinario di Idraulica ICAR/01) School of Engineering, University of Trieste, Trieste, Italy. Date of Birth: Place of Birth: Citizenship: Status: Education 1992 1987 7 Sept 1963 Prato, Italy Italian Married (1989), with 3 children (1996, 2001, 2008) PhD, School of Engineering, University of Padova, Italy Laurea (Master) in Civil Engineering, School of Engineering, University of Firenze, Italy Academic Appointments 2006 – present 2012 – 2013 2009 – 2011 2008 – 2010 2000 – 2001 1998 – 2006 1998 1995 – 1998 1992 – 1998 1994 1992 Full Professor, School of Engineering, University of Trieste, Italy. Sr. Research Associate, Mount Sinai School of Medicine, NY. Adj. Professor of Bioengineering, School of Medicine, Univ. of Firenze. Adj. Professor of Biomechanics, School of Engineering, Univ. of Trieste. Adj. Professor of Hydraulics, School of Engineering, Univ. of Pisa. Associate Professor, School of Engineering, University of Trieste, Italy. Senior Research Associate, University of Cambridge, UK. Adj. Lecturer of Fluid Mechanics, School of Engineering, Univ. Firenze. Permanent Research position, University of Firenze, Italy. Post-Doc, ETSIA, Universidad Politecnica de Madrid, Spain. Post-Doc, INLS, University of California San Diego, CA. Consulting Activities 2006 – present 2001 – present 2004 – 2010 2002 – present 2001 – 2005 TomTec GmbH, Munich, Germany. Advanced Medical Imaging Developments SRL, Italy. Siemens Medical Solutions, Ultrasound, Mountain View, CA. Esaote Spa, Firenze, Italy. Bracco Imaging Spa, Milano, Italy. Professional Association Memberships − European Society of Mechanics (EUROMECH). − American Physical Society (APS). − European Society of Cardiology - European Association of CardioVascular Imaging (ESC-EACVI). − European Research Center of Fluid Turbulence and Combustion (ERCOFTACT), Board of Committee SIG 37 (Biological Fluid Mechanics). Gianni Pedrizzetti PhD Curriculum Vitae – Page 1 Reviewing and Editorial Activity − European Commission assistant on FP7-HEALTH program (3 steps). − Reviewer of grant proposal for European Union, individual European and worldwide countries. − Reviewer for major journals in fluid mechanics, biomechanics, cardiovascular engineering, medical imaging, cardiology. − Associate Editor 2008-2011 for Comm. Nonlinear Systems and Numerical Simulations. − Editor in Chief of a Special Issue of Eur. J Mechanics on CardioVascular Fluid Mechanics. − APS Outstanding Referee in 2010. − Chairman, of the Euromech Colloquium on “CardioVascular Fluid Mechanics”, Cagliari, June 2011. Teaching and Mentoring Activity 1998 – present Course of Hydraulics (Civil and Environmental Engineering), undergraduate level. University of Trieste. Italy. 2009 – 2011 Course of Bioengineering (Sport Medicine), graduate level. University of Firenze. Italy. 2008 – 2010 Biomechanics (Clinical Engineering), graduate level. University of Trieste. Italy. 2006 – 2010 Hydraulics II (Environmental. Engineering), graduate level. University of Trieste. Italy. Public Lectures: invited speaker in numerous conferences/meetings Ph.D. Advisees: 8 Theses. M.S. Advisees: 12 Theses Grant support 2014-2017 PRIN. Italian Minister of Education and Research. Title: Hemodynamics of the aortic valve/artery functional unit. Role: Local PI 2010-2012 Industrial Research Funds. Title: Theoretical analysis of the blood flow in cardiovascular districts of clinical interest. Role: PI 2010 - 2012 American Heart Association (AHA) Grant-in-Aid. Title: Development of 3D Echocardiographic Particle Image Velocimetry for Assessment of Right Ventricular Flow Pattern. Duration: 3 years (started July 2010) Role: Intl. Partner (PI: Arash Kheradvar, University of California Irvine) 2009 - 2014 EU 7th Framework collaborative project. Grant no. 223615, FP7 – HEALTH – 2007-B. Title: Determining Optimal non-invasive Parameters for the Prediction of Left ventricular morphologic and functional Remodeling in Chronic Ischemic Patients. Role: Partner ( Coordinated by Katholieke Universiteit Leuven, Belgium). Gianni Pedrizzetti PhD Curriculum Vitae – Page 2 2008-2010 PRIN. Italian Minister of Education and Research. Title: Cardiac fluid dynamics: interaction between flow and tissues, numerical modeling, and applications. Role: National PI 2006-2008 PRIN. Italian Minister of Education and Research. Title: Cardiovascular fluid dynamics Role: National PI 2004-2006 PRIN. Italian Minister of Education and Research. Title: Cardiac fluid dynamics Role: National PI 2003 - 2005 FIRB. Italian Minister of Education and Research. Title: Fluid mechanics in sites of medical interest Role: Local Unit PI 2002-2004 FIRB. Italian Minister of Education and Research. Title: Technics and innovative methods for the use of contrast agents in echocardiography. Role: External expert 2001-2003 CNR. National Research Center (Agenzia 2000), Italy. Title: Mathematical modeling of the interaction between flow and endovascular prosthesis. Role: Local PI 1999 - 2001 MURST. Italian Minister of Education and Research. Title: Wind analysis control and risk reduction. Role: Local Unit PI 1999-2000 Regional Grants Friuli-Venezia-Giulia (Italy) Title: Information technology for the control of atmospheric dispersion Role: Local PI 1998 - 2000 MURST. Italian Minister of Education and Research. Title: Vortex processes, turbulence and chaos. Role: Local Unit PI 1998 British Council collaborative project with University of Cambridge UK. Title: Phenomena associated with vortex wakes Role: co-PI 1998 Individual grant from European TMR Research Network on "Intermittency in Turbulent Systems", Title: Nonlinear dynamics of vortex phenomena Role: co-PI Gianni Pedrizzetti PhD Curriculum Vitae – Page 3 1995-1997 European INCO-Copernicus ERB IC15CT96-0110 Title: Risk reduction for mercury pollution Role: local-PI 1995-1997 European INTAS funding for East Europe (Kazakhstan) Title: Risk reduction for mercury pollution Role: local-PI 1996 University of Firenze Title: Numerical simulation of restenosis risk after carotid surgery Role: PI 1995 – 1997 ENEL-CRIS (National Electric Company, Hydraulics and Structure Research Center, Italy) Title: Modeling of vortex flow in Francis turbines Role: PI 1994-1996 NATO Office of Scientific Affairs, grant n. SA.5-2-05 CRG 931160 Title: Statistical and stochastic Markov modeling of turbulence Role: PI 1994 European Individual Fellowship ERB CHBICT 940994 Title: Two-dimensional turbulence Role: junior-PI (tutor in ETSIA, Universidad Politecnica Madrid, Spain) 1992 Individual Fellowship University of Firenze Title: Vortex dynamics and turbulence Role: junior-PI (tutor in INLS, University California San Diego, USA) Publications: Books 1. Kheradvar A, Pedrizzetti G. Vortex Formation in the Cardiovascular System. SpringerVerlag London Ltd. 2012 (ISBN 978-1-4471-2287-6). 2. Pedrizzetti G, Perktold K eds. CardioVascular Fluid Mechanics. Springer-Verlag Wien New York 2003 (ISBN 3-211-00538-2). Covers 1. 2. 3. 4. 5. Nature Reviews Cardiology 2013; Vol. 10, No. 1-12 (12 issues). J Am Coll Cardiol Img 2013; Vol. 6, No. 5. Ann Biomed Eng 2012; Vol. 40, No. 8. J Am Coll Cardiol Img 2012; Vol. 5, No. 3. J Am Coll Cardiol Img 2008; Vol. 1, No. 6. Published Journal Articles 1. Pedrizzetti G, Domenichini F. Left Ventricular Fluid Mechanics: the long way from theoretical models to clinical applications. Ann Biomed Eng 2014; DOI: 10.1007/s10439014-1101-x Gianni Pedrizzetti PhD Curriculum Vitae – Page 4 2. Pedrizzetti G, Sengupta S, Caracciolo G, Park CS, Amaki M, Goliasch G, Narula J, Sengupta PP. Three-dimensional Principal Strain Analysis for Characterizing Subclinical Changes in Left Ventricular Function. J Am Soc Echocardiogr 2014; doi:10.1016/j.echo.2014.05.014. 3. Stefani L, De Luca A, Toncelli L, Pedrizzetti G, Galanti G. 3D Strain Helps Relating LV Function to LV and Structure in Athletes. Cardiovasc Ultrasound 2014; 2:33. 4. Pedrizzetti G, La Canna G, Alfieri O, Tonti G. The vortex - an early predictor of cardiovascular outcome. Nature Reviews Cardiology 2014; doi:10.1038/nrcardio.2014.75. 5. Amaki M, Savino J, Ain DL, Sanz J, Pedrizzetti G, Kulkarni H, Narula J, Sengupta PP. Diagnostic Concordance of Echocardiography and CMR-based Feature Tracking for Differentiating Constrictive Pericarditis from Restrictive Cardiomyopathy. Circ Cardiovasc Imaging 2014; doi: 10.1161/?CIRCIMAGING.114.002103. 6. Agati L, Cimino S, Tonti G, Cicogna F, Petronilli V, Pedrizzetti G. Quantitative Analysis of Intraventricular Blood Flow Dynamics by Echocardiographic Particle Image Velocimetry in Patients with Acute Myocardial Infarction at Different Stages of Left Ventricular Dysfunction. Eur Heart J Cardiovasc Imaging 2014; doi:10.1093/ehjci/jeu106. 7. Pedrizzetti G, Mangual J, Tonti G. On the Relationship between Global Longitudinal Strain and Ejection Fraction. J Biomech 2014; 47:746-749. 8. Hong GR, KIm M, Pedrizzetti G, Vannan MA. Current Clinical Application of Intracardiac Flow Analysis Using Echocardiography. J Cardiovascular Ultrasound 2013;21:155–162. 9. Mangual JO, De Luca A, Kraigher-Krainer E, Toncelli L, Shah A, Solomon S, Galanti G, Domenichini F, Pedrizzetti G. High-Tech Assessment of Left Ventricular Flow in Dilated Cardiomyopathy. J Biomech 2013;46:1611–1617 10. Caracciolo G, Goliasch G, Amaki M, Bansal M, Nakabo A, Haruiko A,Scott L, Lipar L, Pedrizzetti G, Narula J, Sengupta PP. Myocardial stretch in early systole is a key determinant of the synchrony of left ventricular mechanical activity in vivo. Circulation Journal 2013; doi: 10.1253/circj.CJ-12-1230. 11. Goliasch G, Goscinska-Bis K, Caracciolo G, Nakabo A, Smolka G, Pedrizzetti G, Narula J, Sengupta PP. CRT Improves Left Ventricular Filling Dynamics: Insights From Echocardiographic Particle Imaging Velocimetry. J Am Coll Cardiol Img 2013; http://dx.doi.org/10.1016/j.jcmg.2013.04.004 12. Mangual JO, Föll D, Jung B, Pedrizzetti G, Kheradvar A. Aging does not Affect Radial Viscoelastic Behavior of the Left Ventricle. Cardiology 2013; 125:38-49. 13. Abe H, Caracciolo G, Kheradvar A, Pedrizzetti G, Khandheria BK, Narula J, Sengupta PP. Left Ventricular Efficiency in Heart Failure is Related to the Intracavitary Vortex Strength During Isovolumic Contraction. Eur Heart J, Cardiov Imag2013; doi:10.1093/ehjci/jet049. 14. Dini FL, Guarini G, Pedrizzetti G, Miccoli M, Zito MC, Baggiani A, Conti U, Di Bello V, Marzilli M. Ultrasound Assessment of the Force-frequency Relationship from the Law of Conservation of Momentum in Patients with Left Ventricular Dysfunction. Ultrasound in Medicine & Biology 2013; 39:585-591. 15. Padiyath A, Gribben P, Li L, Rangamani S, Schuster A, Danford DA, Pedrizzetti G, Kutty S. Echocardiography and cardiac magnetic resonance based feature tracking in the assessment of myocardial mechanics in tetralogy of fallot: an intermodality comparison. Echocardiography 2013; 30:203-210. 16. Mangual JO, De Luca A, Toncelli L, Domenichini F, Galanti G, Pedrizzetti G. Three Dimensional Reconstruction of the Functional Strain-Line Pattern in the Left Ventricle from 3D Echocardiography. Circulation Imaging 2012; 5:808-809. 17. Bhatti S, Al-Khalidi H, Hor K, Hakeem A, Taylor M, Quyyumi AA, Oshinski J, Pecora AL, Kereiakes D, Chung E, Pedrizzetti G, Miszalski-Jamka T, Mazur W. Assessment of Myocardial Contractile Function Using Global and Segmental Circumferential Strain following Intracoronary Stem Cell Infusion after Myocardial Infarction: MRI Feature Tracking Gianni Pedrizzetti PhD Curriculum Vitae – Page 5 Feasibility Study. ISRN Radiology 2013;2013:371028 http://dx.doi.org/10.5402/2013/371028). 18. Stefani L, Pedrizzetti G, De Luca A, Mercuri R, Innocenti G, Toncelli L, Vono MCR, Pedri S, Galanti G. Assessment of left ventricle twisting in athletes with Bicuspid Aortic Valve. British Journal of Medicine and Medical Research 2012; 2:575-586. 19. Pedrizzetti G, Kraigher-Krainer E, De Luca A, Caracciolo G, Mangual JO, Shah A, Toncelli L, Domenichini F, Tonti G, Galanti G, Sengupta PP, Narula J, Solomon S. Functional Strain-line Pattern in the Human Left Ventricle. Phys Rev Lett 2012; 109:048103. 20. Sengupta PP, Pedrizzetti G, Narula J. Multiplanar Visualization of Blood Flow Using Echocardiographic Particle Imaging Velocimetry. J Am Coll Cardiol Img 2012; 5:566-569. 21. Sengupta PP, Pedrizzetti G, Kilner P., Kheradvar A, Ebbers T, Frazer A, Tonti G, Narula J. Emerging Trends in Clinical Assessment of Cardiovascular Fluid Dynamics. J Am Coll Cardiol Img 2012; 5:305-316. 22. Mangual J, Domenichini F, Pedrizzetti G. Describing the highly 3D flow in the right ventricle. ABME 2012; 40:1790-1801. 23. Cimino S, Pedrizzetti G, Tonti G, Canali E, Petronilli V, De Luca L, Iacoboni C, Agati L. In vivo Analysis of Intraventricular Fluid Dynamics in Healthy Hearts. European Journal of Mechanics B/Fluids 2012; 35:40-46. (Special Issue: Cardiovascular Flows). 24. Vukicevic M, Fortini S, Querzoli G, Cenedese A, Pedrizzetti G. Experimental study of the asymmetric heart valve prototype. European Journal of Mechanics B/Fluids 2012; 35:5460. (Special Issue: Cardiovascular Flows). 25. Mangual J, Domenichini F, Pedrizzetti G. Three dimensional numerical assessment of the right ventricular flow using 4D echocardiography boundary data. European Journal of Mechanics B/Fluids 2012; 35:25-30. (Special Issue: Cardiovascular Flows). 26. De Luca A, Stefani L, Pedrizzetti G, Pedri S, Galanti G. The effect of exercise training on left ventricular function in young elite athletes. Cardiovascular Ultrasound 2011; 9:27. 27. Vukicevic M, Pedrizzetti G. On the opening of a wall-mounted leaflet by a single flow pulse. Phys Rev E 2011; 84:017301. 28. Hor KN, Baumann R, Pedrizzetti G, Tonti G, Gottliebson WM, Taylor M, Benson W, Mazur W. Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking. JoVE 2011; 48, doi: 10.3791/2356. 29. Vukicevic M., Pedrizzetti G. Role of inertia in the interaction between oscillatory flow and a wall-mounted leaflet. Phys Rev E 2011; 83 (1):016310. 30. Domenichini F, Pedrizzetti G. Intraventricular vortex flow changes in the infarcted left ventricle. Computer Methods in Biomechanics and Biomedical Engineering 2011; 14 (1). 31. de Tullio MD, Pedrizzetti G, Verzicco R. On the influence of the aortic root geometry on blood flow after a bileaflet mechanical heart valve implant: a numerical study. Acta Mechanica 2011; 216:147-163. 32. Pedrizzetti G. Vortex formation out of two-dimensional orifices. J Fluid Mech 2010; 655:198-216. 33. Faludi R, Szulik M, D’hooge J, Herijgers P, Rademakers F, Pedrizzetti G, Voigt J-U. Left ventricular flow patterns in healthy subjects and patients with prosthetic mitral valves: An in vivo study using echocardiographic particle image velocimetry. J Thorac Cardiovasc Surg 2010; 139:1501-1510. 34. Pedrizzetti G, Domenichini F, Tonti G. On the left ventricular vortex reversal after mitral valve replacement. Ann Biomed Eng 2010; 38:769-773. Gianni Pedrizzetti PhD Curriculum Vitae – Page 6 35. Kheradvar A, Houle H, Pedrizzetti G, Tonti G, Belcik T, Ashraf M, Lindner J, Gharib M, Sahn D. Echographic Particle Image Velocimetry: a novel technique for quantification of left ventricular blood vorticity pattern. J Am Soc Echocardiogr 2010; 23:86-94. 36. Stefani L, Pedrizzetti G, De Luca A, Mercuri R, Innocenti G, Galanti G. Real-time Evaluation of Longitudinal Peak Systolic Strain (Speckle Tracking Measurement) in Left and Right Ventricles of Athletes. Cardiovascular Ultrasound 2009; 7:17. 37. Stefani L, De Luca A, Maffulli N, Mercuri R, Innocenti G, Suliman I, Toncelli L, Vono MC, Cappelli B, Pedri S, Pedrizzetti G, Galanti G. Speckle tracking for left ventricle performance in young athletes with bicuspid aortic valve and mild aortic regurgitation. Eur J Echocard 2009; 10:527-531. 38. Hong GR, Pedrizzetti G, Tonti G, Li P, Wei Z, Kim JK, Bawela A, Liu S, Chung N, Houle H, Narula J, Vannan MA. Characterization and Quantification of Vortex Flow in the Human Left Ventricle by Contrast Echocardiography Using Vector Particle Image Velocimetry. JACC Cardiov Imaging 2008; 1:705-717. 39. Stefani L, Toncelli L, Di Tante V, Vono MCR, Moretti A, Cappelli B, Pedrizzetti G, Galanti G. Supernormal functional reserve of apical segments in elite soccer players : an ultrasound speckle tracking handgrip stress study. Cardiovascular Ultrasound 2008; 6:14. 40. Pedrizzetti G, Domenichini F. Asymmetric opening of a simple bi-leaflet valve.Phys Rev Lett 2007; 98:214503. 41. Stefani L, Toncelli L, Gianassi M, Manetti P, Di Tante V, Vono MCR, Moretti A, Cappelli B, Pedrizzetti G, Galanti G. Two-dimensional tracking and TDI are consistent methods for evaluating myocardial longitudinal peak strain in left and right ventricle basal segments in athletes. Cardiovascular Ultrasound 2007; 5:7. 42. Domenichini F, Querzoli G, Cenedese A, Pedrizzetti G. Combined experimental and numerical analysis of the flow structure into the left ventricle. J Biomech 2007; 40:19881994. 43. Pedrizzetti G, Domenichini F. Flow-driven opening of a valvular leaflet. J Fluid Mech 2006; 569:321-330. 44. Pedrizzetti G. Left Ventricular Fluid Dynamics. Ercoftac Bull 2006; 68:25-28. 45. Di Bello V, Santini F, Di Cori A, Pucci A, Palagi C, Delle Donne MG, Giannetti M, Talini E, Nardi C, Pedrizzetti G, Fierabracci P, Vitti P, Pinchera A, Balbarini A. Relationship between preclinical abnormalities of global and regional left ventricular function and insulin resistance in severe obesity: a Color Doppler Imaging Study. International Journal of Obesity 2006; 30:948-956. 46. Vannan MA, Pedrizzetti G, Li P, Gurudevan S, Houle H, Main J, Jackson J, Nanda N. Effect of Cardiac Resynchronization Therapy on Longitudinal and Circumferential Left Ventricular Mechanics by Velocity Vector Imaging: Description and Initial Clinical Application of a Novel Method Using High-Frame Rate B-Mode Echocardiographic Images. Echocardiography 2005; 22:826-830. 47. Pedrizzetti G, Domenichini F. Nature optimizes the swirling flow in the human left ventricle. Phys Rev Lett 2005; 95:108101. 48. Domenichini F, Pedrizzetti G, Baccani B. Three-dimensional filling flow into a model left ventricle. J Fluid Mech 2005; 539:179-198. 49. Pedrizzetti G. Kinematic characterization of valvular opening. Phys Rev Lett 2005; 94:194502. 50. Agati L, Tonti G, Pedrizzetti G, Magri F, Funaro S, Madonna M, Celani F, Messager T, Broillet A. Clinical application of quantitative analysis in real-time MCE. Eur J Echocardiography 2004; 45:S9-S15. Gianni Pedrizzetti PhD Curriculum Vitae – Page 7 51. Agati L, Tonti G, Pedrizzetti G. Clinical Application of Quantitative Analysis in Myocardial Contrast Echocardiography. In: Contrast Echocardiography in Clinical Practice, JL Zamorano, MA Garcia-Fernandez eds. Springer 2004. ISBN 88-470-0237-0. 52. Tortoriello A, Pedrizzetti G. Flow-tissue interaction with compliance mismatch in a model stented artery. J Biomechanics 2004; 37:1-11. 53. Grigioni M, Tonti G, Pedrizzetti G, Daniele C, D'Avenio G. In vitro assessment of a new algorithm for quantitative echo measurement of heart valve regurgitant jet. Proc. SPIE Int. Soc. Opt. Eng. 2003; 5035:287-297. 54. Bolzon G, Zovatto L, Pedrizzetti G. Birth of three-dimensionality in a pulsed jet through a circular orifice. J Fluid Mech 2003; 493:209-218. 55. Baccani B, Domenichini F, Pedrizzetti G. Model and influence of mitral valve opening during the left ventricular filling. J Biomechanics 2003; 36:355-361. 56. Baccani B, Domenichini F, Pedrizzetti G. Vortex dynamics in a model left ventricle during filling. Eur J Mech B/Fluids 2002; 21:527-543. 57. Amodeo A, Grigioni M, Oppido G, Daniele C, D'Avenio G, Pedrizzetti G, Giannico S, Filippelli S, Di Donato R. The beneficial vortex and best spatial arrangement in total extracardiac cavopulmonary connection. J Thorac Cardiovasc Surg 2002; 124:471-478. 58. Pedrizzetti G, Domenichini F, Tortoriello A, Zovatto L. Pulsatile flow inside moderately elastic arteries, its modelling and effects of elasticity. Computer Methods in Biomechanics and Biomedical Engineering 2002; 5:219-231. 59. Baccani B, Domenichini F, Pedrizzetti G, Tonti G. Fluid dynamics of the left ventricular filling in dilated cardiomiopathy. J Biomechanics 2002; 35:665-671. 60. Bolzon G, Pedrizzetti G, Grigioni M, Zovatto L, Daniele C, D'Avenio G. Flow on the symmetry plane of a total cavo-pulmonary connection. J Biomechanics 2002; 35:595-608. 61. Tonti G, Pedrizzetti G, Trambaiolo P, Salustri A. Space and time dependency of inertial and convective contribution to the transmitral pressure drop during ventricular filling. J Am Coll Card 2001; 38:290-291. 62. Zovatto L, Pedrizzetti G. Flow about a circular cylinder between parallel walls. J Fluid Mech 2001; 440:1-25. 63. Pedrizzetti G, Vassilicos JC. Interscale transfer in 2D compact vortices. J Fluid Mech 2000; 406:109-129. 64. Pedrizzetti G. Quadratic Markov modeling for intermittent turbulence. Phys Fluids 1999; 11:1694-1696. 65. Pedrizzetti G. Fluid flow in a tube with an elastic membrane insertion. J Fluid Mech 1998; 375:39-64. 66. Pentek A, Kadtke JB, Pedrizzetti G. Dynamical control for capturing vortices near bluff bodies. Phys Rev E 1998; 58:1883-1898. 67. Domenichini F, Pedrizzetti G. Impulsively started flow separation in wavy-walled tubes. J Fluid Mech 1998; 359:1-22. 68. Pedrizzetti G, Domenichini F. Impulsive and pressure-driven transient flows in closed ducts. Phys Fluids 1997; 9:3575-3577. 69. Domenichini F, Pedrizzetti G, de Bernardinis B. A model for pressure distribution over obstacles due to separated flow. J Wind Eng Ind Aerod 1997; 66:51-67. 70. Pedrizzetti G. Unsteady tube flow over an expansion. J Fluid Mech 1996; 310:89-111. 71. Pedrizzetti G, Novikov EA, Praskovsky AA. Self-similarity and probability distributions of turbulent intermittency. Phys Rev E 1996; 53:475-484. Gianni Pedrizzetti PhD Curriculum Vitae – Page 8 72. Kadtke J, Pentek A, Pedrizzetti G. Controlled capture of a continuous vorticity distribution. Phys Lett A 1995; 204:108-114. 73. Luithardt HH, Kadtke JB, Pedrizzetti G. Capture of vortices by a moving body II: bound pair model. Chaos 1994; 4:681-691. 74. Pedrizzetti G, Novikov EA On Markov modeling of turbulence. J Fluid Mech 1994; 280:6993. 75. Pedrizzetti G, Kadtke JB, Luithardt HH. Chaotic trapping phenomena in extended systems. Phys Rev E 1993; 48:3299-3308. 76. Pedrizzetti G, Novikov EA. Instability and chaos in axisymmetric vortex-body interactions. Fluid Dynamics Research 1993; 12:129-151. 77. Sakay Y, Hunt JCR, Fung JCH, Pedrizzetti G, et al. Modelling of the diffusion of fluid particles in turbulent flows approaching a circular cylinder by random Fourier modes and random flight. Applied Scientific Research 1993; 51:547-553. 78. Pedrizzetti G. Close interaction between a vortex filament and a rigid sphere. J Fluid Mech 1992; 245:701-722. 79. Pedrizzetti G. Insight into Singular Vortex Flows. Fluid Dynamics Research 1992; 10:101116. 80. Pedrizzetti G. Space Temporal Maps for Vortical Flow Field Construction. Meccanica 1991; 26:33-36. 81. Hunt JCR, Kawai H, Ramsey SR, Pedrizzetti G, Perkins RJ. A Review of Velocity and Pressure Fluctuations in Turbulent Flows around Bluff Bodies. J Wind Eng Ind Aerod 1990; 35:49-85. Patents (designed co-inventor): 1. M-tracking for space-time imaging. EP1478277. 2. Flow-rate conservative Doppler estimate. EP1511974, US7270635. 3. A Method for Generating Time Independent Images of Moving Objects... US6909914, EP1519315. 4. Method for estimating tissue velocity vectors and tissue deformation from ultrasonic diagnostic imaging data. EP1520517. 5. A Method of tracking position and velocity of objects borders in two or three dimensional digital images, particularly in echographic images. US7343031, EP1522875. 6. A measurement method of time varying events in a target body and a method for displaying measurement data of different parameters of a target... US2006/0281993. 7. Method for registering images of a sequence of images, particularly ultrasound diagnostic images. US2008/0095417. 8. Method and System for managing and displaying medical data. US 2012/0046972, SIPO CN102414688. + Seven additional pending patent submissions, undisclosed, filed on US or European patent office. Contribution in Industrial Products (recognized by an industrial partner): 1. Qontrast. Distributed by: Esaote S.p.A. and Bracco Imaging S.p.A., Italy (2004-2009). Gianni Pedrizzetti PhD Curriculum Vitae – Page 9 2. 2D Velocity Vector Imaging (2D-VVI). Distributed by: Siemens Medical Solutions Inc., USA (2005-present). 3. X-Strain. Distributed by: Esaote S.p.A., Italy (2007-present). 4. 2D Cardiac Performance Analysis (2D-CPA). Distributed by: TomTec GmbH, Germany (2009-present). 5. Contrast Dynamics. Distributed by: Siemens Medical Solutions Inc, USA (2009-present). 6. Omega Flow. Distributed by: Siemens Medical Solutions Inc, USA (2009-2011). 7. VevoStrain. Distributed by: VisualSonics Inc., Canada (2010-present). 8. Speckle Tracking Strain. Distributed by: Samsung-Medison Co., South Korea (2011present). 9. 4D Left Ventricular Analysis 3.0 (4D LVA 3.x). Distributed by: TomTec GmbH, Germany (2012-present). 10. Cardiac Performance Analysis - Magnetic Resonance (CPA-MR). Distributed by: TomTec GmbH, Germany (2012-present). 11. VevoVasc. Distributed by: VisualSonics Inc., Canada (2013-present). 22 October 2014 Gianni Pedrizzetti PhD Curriculum Vitae – Page 10