Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG IBP ( Invasive BP ) measurement diaphragm Blood vessel catheter Pi cable Po pill up with some liquid (ex.saline) strain gages Pi Po t t If we choose sticky and dense liquid, We can’t get the signal of Pi just like the graph. To get the signal, We should concern with distance, diameter of a catheter and liquid, airbubble inside a catheter. IBP ( Invasive BP ) measurement # Equivalent Circuit Model Of Catheter-Sensor System (1) Resistance L A Electrical resistance : V Ri , R V L A resistivity F ( P1 P2) P1 R P2 Liquid resistance : op R F R L A viscosity IBP ( Invasive BP ) measurement (2) Capacitance or Compliance iC dv A , C dt x dp f C dt (3) Inductance or Inertance di V L dt df PL , dt m L 2 A C Y Young's modulus IBP ( Invasive BP ) measurement multi physics Electric Circuit Fluid Mechanics voltage current charge V L [ ] ( ) I A V L dI dt I C dV dt R pressure flow volume Pa s R [ F 8L ) 3 ] ( 4 m r L ( 2 ) r P dF dt C Young's modulus L Equivalent Circuit Model of IBP catheter Pi Rc Po diaphragm cable Vi liquid strain gages Lc i + Vo - Cd Compliance of diaphragm dV0 di Vi Rc i Lc V0 i Cd dt dt dV0 d 2V0 Vi V0 Rc Cd Lc Cd : 2nd order ODE 2 dt dt d Rc Cd D : operator K 1, dt 2 Lc damping D 2 2D 1 ratio [ 2 1] Vo (t ) KVi (t ) Wn Wn Wn Lc Cd natural frequency Equivalent Circuit Model of IBP (1) Frequency Transfer Function H ( jw) Vo ( jw) 1 1 Vi ( jw) ( jw ) 2 2 jw 1 1 ( w ) 2 j 2 w Wn Wn Wn Wn w 2 Wn 1 H ( jw) tan1 ( ) w 2 w 2 2 2 w 2 1 ( ) [1 ( ) ] 4 ( ) Wn Wn Wn 1 [1 ( w 2 2 w ) ] 4 2 ( ) 2 Wn Wn 1 tan ( 2 w Wn Wn w ) Equivalent Circuit Model of IBP 0.5 (underdamped) |H| 1 (criticallydamped) 2 (overdamped) Wn ∠H w w 0.5 (underdamped) -π/2 1 (criticallydamped) 2 (overdamped) -π Equivalent Circuit Model of IBP d 2V0 dV LC 2 RC 0 Vo Vi dt dt Methods to solve 2nd order ODE (1) LCD 2Vo RCDVo Vo Vi ( LCD RCD 1)Vo Vi 2 d D dt Vo 1 H ( D) Vi LCD 2 RCD 1 : operational transferfunction (2) LC ( jw) 2 Vo RCjwVo Vo Vi H ( jw) Vo 1 Vi LC ( jw) 2 RC( jw) 1 H ( D) D jw Steady State Freq. Response |H| ∠H K -4/π 0.5 f1 f2 -1.8π f1 f2 f Vi (t ) A sin(2f1t ) Vo (t ) KA sin(2f1t ) 4 Vi (t ) A sin(2f 2t ) Vo (t ) 0.5 A sin(2f 2t 1.8 ) Unit Step Response In reality, We need a unit step function for a starting point. For example, Vi (t ) A sin(2f1t ) should be Vi (t ) A sin(2f1t ) u(t ) underdamping input signal overdamping critical damping Transient Step Response Po balloon P bulb saline overdamping critical damping underdamping Example (7.1) A 5mm-long air bubble has formed in the rigid-walled catheter to a Statham P23Dd sensor. The catheter is 1m long, 6 French diameter, and filled with water at 20 ℃. Plot the frequency-response curve of the system with and without the bubble. r 1 P 12 fn ( ) 91Hz 2 L L 4 L V 12 3( ) 0.033 r P f n,bub 22Hz bub 0.137 1.34 1.95 log f Example (7.2) By changing only the radius of the catheter, redesign the (no-bubble) catheter of Figure 7.9 to achieve the damping ratio ζ=1. Calculate the resulting natiral frequency fn. r 3 r0 0 3 r 3 0.0032 r 0.147 f n f n 0 r r0 f n 29Hz 1.46 log f Thank you.