Introduction to Human Nutrition Course Web Page Real Hope for Haiti – Clinic for Malnourished Children Chapter Outline Nutrition defined Classifying the nutrients Nutritional research – now in CH 2 Nutrition and health Healthy People 2020 goals Factors impacting food choices Small group exercise Nutritional Goals Quality intake that allows you to function at your best and promotes health. Intake that provides adequate levels of each nutrient Quantity of intake that promotes a healthy body weight. Nutrition Defined – the science of foods and the nutrients they contain Nutrition Study the: action of foods and the nutrients in the body relationship between diet and health Nutrition Defined Actions in the body include: Ingestion Digestion Absorption Transport Metabolism Excretion What’s Considered Food? Foods contain nutrients and are derived from plant or animal sources Nutrients are used by the body to provide energy and to support growth, maintenance and repair of body tissues ~ 40 nutrients identified at this time Classifying Nutrients (1.3) There are 6 Classes of Nutrients 1. 2. 3. 4. 5. 6. Carbohydrates Lipids (fats) Proteins Vitamins Minerals Water Body Composition Describing the Nutrients There are several ways to classify the classes of nutrients. Essential or nonessential Organic or inorganic Macronutrient or micronutrient Energy yielding or not Classifying Nutrients nutrients – nutrients the body either cannot make or cannot make enough of to meet its needs. Essential These nutrients must be obtained from foods (ingested in some manner) Examples: • Vitamins • Calcium, iron, and other minerals • Some of the amino acids Essential Nutrients To be classified as an essential nutrient: The biological function of nutrient is known Omission from the diet leads to a decline in a biological function Return of the nutrient restores the biological function Classifying Nutrients nutrients – body can make from other nutrients ingested Nonessential Examples: • Cholesterol • Some amino acids Classifying Nutrients by Composition Organic nutrients - contain carbon • Carbohydrates • Lipids • Proteins • Vitamins Inorganic nutrients - do not contain carbon • Minerals • Water Quantity Needed Macronutrients: need in relatively large amounts Carbohydrates, lipids, proteins Micronutrients: need in relatively small amounts All other nutrients Classifying Nutrients Energy-yielding nutrients (3): Carbohydrates Fats (lipids) Proteins Where does the energy come from? A little more on energy Measure energy in kilocalories in U.S. What most think of as a “calorie” is really a kilocalorie Kcal = amount of energy needed to raise the temperature of 1 kg of water by 10C Measure energy in kilojoules (kJ) in most other countries Energy in the Body The body uses the energy yielding nutrients to fuel all activities If All energy yielding nutrients are “caloric”. more energy is ingested than is needed to fuel body activities the extra energy is stored as _________ and ________ occurs. Energy-Yielding Nutrients Energy-Yielding Nutrients Carbohydrates: C, H, O 4 kcal/gram Body’s primary source of energy • Use as glucose • Glucose is the brain’s only source of energy Carbohydrate stores are limited ~12-24 hours (in liver and muscle) Classes of Carbohydrates Simple sugars Monosaccharides and disaccharides Complex carbohydrates Starch Fibers Carbohydrate rich foods…….. Lipids Lipids – fats and oils: C, H, O 9 kcal/gram Body’s alternate source of energy • Use fat along with glucose as an energy source most of the time Stores are unlimited Types of Lipids – solids Oils – liquids Saturated (solids/fats) Fats No carbon to carbon double bonds Unsaturated (liquids/oils) Carbon to carbon double bond(s) present Lipid rich foods? Proteins Proteins: C, H, O, N, S 4 kcal/gram (same as _______) Body’s least desirable source of energy • WHY? ……. Protein is used for energy only when carbohydrate is NOT available as an energy source. Protein rich foods? Energy-Yielding Non-nutrient Alcohol – 7 kcal/gram Non-nutrient because it interferes with growth, maintenance and repair of the body Alcohol’s metabolites are harmful No required functions in the body Energy Density Measure of the kcal per gram of food _______ has the highest energy density of the 3 energy-yielding nutrients. Foods with a high energy density provide more kcal per gram than low density foods. Energy Density Evaluating a Food Label _____ grams carbohydrate _____ grams fat _____ grams protein TOTAL KCAL: ____________ 6 Classes of Nutrients • • • Carbohydrates Lipids (fats and oils) Proteins Vitamins Minerals Water Vitamins Essential Organic, micronutrient Not energy-yielding Can be water-soluble or fat-soluble Examples: Minerals Essential Inorganic, micronutrient Major minerals: Ca, P, Na Trace minerals: Fe, Zn Not energy-yielding Indestructible Water Water (H2O) Essential Organic or inorganic? Noncaloric We are ~60% water Not everyone has access to clean water The Science of Nutrition One of the newest sciences New branch is nutritional genomics • Study of the interaction of nutrients with DNA/genes and how those genes impact health Like all sciences, nutrition is based on scientific research Skip to slide 53 – Nutrition and health Scientific Method 1. 2. 3. 4. 5. Observations Questions Hypotheses Predictions Test hypotheses/predictions Analyze data and draw conclusions Share results Observations and Questions Make observations about diet and health. These observations lead to questions For example: The incidence of breast cancer is much lower in Japan than in the U.S. Diet in Japan is rich in…..while in U.S. diet is rich in …… Question?: Develop Hypotheses and Make Predictions – tentative explanation of the observations or answer to the question Hypothesis prediction – If the hypothesis is true what else is true? Make Experiments Conduct experiments to test the predictions Easier said than done when people are involved! We’ll consider research designs later/soon. One Experimental Design When possible, randomly assign subjects to either a control of experimental group Goal is for two groups to be as similar to each other as possible Control Group – either no change to diet or given a placebo Experimental group – diet changed or given a supplement Experimental Design Compare the health/lab values of the two groups before and after the diet change. Example – DASH diet study Analyze results… Analyze results Draw conclusions about the validity of the hypothesis Test alternate hypotheses Share findings Publish in nutritional journals Present findings at conferences Common Research Designs Epidemiological study (observe) 1. Cross-sectional Longitudinal Case-control study Experimental (intervene) 2. Animal studies Human clinical trials • Double blind study Lab studies The Science of Nutrition 1. Epidemiological studies • Study of populations • Look for correlations between dietary practices and health • Nurses Health Study Epidemiological Studies Cross-sectional - look for correlations between diet and health at a point in time Longitudinal Studies - Follow a group of people (a cohort) over a period of time • Look for differences in diet that might account for the differences in health Epidemiological Studies study – compare the diet of individuals with a condition to that of healthy individuals Case-control Again, do not change their diet…..just observe it. Human Experimental Studies Often called a Clinical Study • Randomly assign like people to either the experimental or control group • Alter the diet of experimental group as compared to a control group • Compare incidence of disease/lab values/ performance …. of two groups Types of Clinical Trials Blind experiments • Subjects do not know which group they are in Double blind experiments • Neither subjects nor the researchers know which group the subjects are in until after the experiment is over • Goal is to avoid bias in the reporting/recording of the data. Experimental Studies Animal Studies • Controlled studies in lab setting using animals • Alter diet of experimental group • Compare health/lab values of control and experimental groups • Benefits? …. • Drawbacks? …… Experimental Studies Lab-Based Studies • • Also called in vitro studies Examine impact of a substance on living tissue in a “test tube” ------------------------------------------------------------- The Science of Nutrition Size matters Good studies have relatively large sample sizes Preliminary studies have smaller sample sizes Peer review matters Information in peer- reviewed research journals is much more credible than that in popular magazines, TV, Internet Diet and Health Diet - the foods one consumes •The quality of your daily diet affects the risk of chronic diseases Meaning…..The food choices you make daily have a cumulative impact on your health Nutrition and Health Chronic health issues associated with diet include: Heart disease Hypertension Obesity Type II Diabetes Osteoporosis Improving your Health Goal is to reduce the number of risk factors that are in your control Risk factor = something that statistically increases the incidence of a disease • Risk factors may not be the cause of the disease Leading Causes Death - US 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. Heart disease: 616,067 Cancer: 562,875 Stroke: 135,952 Chronic respiratory diseases: 127,924 Accidents (unintentional injuries): 123,706 Alzheimer's disease: 74,632 Diabetes: 71,382 Influenza and Pneumonia: 52,717 Kidney disease: 46,448 Septicemia: 34,828 CDC, 2009 Leading Causes Death - US 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. Heart disease: 596,577 Cancer: 576,691 Chronic lower respiratory diseases: 142,943 Stroke (cerebrovascular diseases): 128,932 Accidents (unintentional injuries): 126,438 Alzheimer's disease: 84,974 Diabetes: 73,831 Influenza and Pneumonia: 53,826 Kidney disease: 45,591 Intentional self-harm (suicide): 39,518 CDC, 2010 data Improving Health Risk factors in your control: Smoking Alcohol intake Over-consumption of calories Physical inactivity Poor quality diet Improving Health Risk factors you cannot control: Age Gender Genetics (family history) Ethnicity Maine Data 27% report NO physical activity 1 in 5 engage in moderate physical activity ~5 days/week 74% do NOT eat 5 servings of fruits and vegetables daily 28.9% of Maine adults are obese (2013) Healthy People 2020 Americans with a healthful diet: Consume a variety of nutrient-dense foods within and across the food groups, especially: • whole grains, fruits, vegetables, low-fat or fat-free milk or milk products, and lean meats and other protein sources. Limit the intake of saturated and trans fats, cholesterol, added sugars, sodium (salt), and alcohol. Healthy People 2020 Limit caloric intake to meet caloric needs. All Americans should avoid unhealthy weight gain, and those whose weight is too high may also need to lose weight Food Choices Small group exercise What influences your food choices each day? Why do you eat what you eat? Get into groups of ~4 and make a list of what impacts your food choices most days. • Turn this list in next time we meet. Food Choices – Text Answers 1. 2. 3. 4. 5. 6. 7. Personal preferences Habit Ethnic heritage Tradition Social interactions or pressure Availability Convenience Economy $ 9. Positive or negative associations 10. Emotional Comfort 11. Values -Religious, 8. political, environmental Health concerns 13. Nutritional value 12.