Prebiotics and probiotics Prebiotics • Prebiotics are food substances that promote the growth of certain bacteria (generally beneficial) in the intestines. • prebiotics—nondigestible food ingredients that selectively stimulate the growth and/or activity of beneficial microorganisms already in people's colons. • When probiotics and prebiotics are mixed together, they form a synbiotic • PREBIOTICS Prebiotics are the substances, which reach to colon in intact form i.e. without getting depleted by the gastric pH and digestive acids. • These prebiotics also selectively promote the growth of colonel probiotic bacteria; hence they act as fertilizers for these bacteria. • These are collective term for non-digestive but a fermentable dietary carbohydrate that may selectively stimulates growth of certain bacterial groups’ resident in the colon, such as Bifidobacteria, Lactobacilli considered to be beneficial for the human host. • inulin, which is soluble dietary fibres and resistant to digestive enzyme and thus reaches to large intestine or colon essentially intact, where it is fermented by resistant bacteria, Lactobacilli and feed themselves on it. • Prebiotics in the Diet: • Prebiotics that feed the beneficial bacteria in your gut mostly come from carbohydrate fibers called oligosaccharides. • You don't digest them, so the oligosaccharides remain in the digestive tract and stimulate the growth of beneficial bacteria. • Sources of oligosaccharides include fruits, legumes, and whole grains. • Fructo-oligosaccharides may be taken as a supplement or added to foods. • Yogurt made with bifidobacteria contain oligosaccharides • • • • Sources Traditional dietary sources of prebiotics include soybeans, inulin source(such as chicory root), raw oats, unrefined wheat and unrefined barley . Some of the oligosaccharides that naturally occur in breast milk are believed to play an important role in the development of a healthy immune system in infants. No plant or food is a prebiotic: Wheat, honey and many other foods contain prebiotics to a greater or lesser extent, ranging from fairly large portions (chicory root, Jerusalem artichoke) to only trace quantities (thousands of other plant-based foods). • • • • • • • • • • • • • Top 10 Foods Containing Prebiotics Food Prebiotic Fiber Content by Weight Raw Chicory Root 64.6% Raw Jerusalem Artichoke 31.5% Raw Dandelion Greens 24.3% Raw Garlic 17.5% Raw Leek 11.7% Raw Onion 8.6% Cooked Onion 5% Raw Asparagus 5% Raw Wheat bran 5% Whole Wheat flour, Cooked 4.8% Raw Banana 1% Probiotics • According to the currently adopted definition by FAO/WHO (World Health Organization and the Food and Agriculture Organization of the United Nations),, probiotics are: "live microorganisms, which, when administered in adequate amounts, confer a health benefit on the host." (Microorganisms are tiny living organisms—such as bacteria, viruses, and yeasts—that can be seen only under a microscope.) • Probiotics: Dietary supplements containing potentially beneficial bacteria or yeast. • Lactic acid bacteria (LAB) and bifidobacteria are the most common types of microbes used as probiotics; but certain yeasts and bacilli may also be helpful. • Probiotics are commonly consumed as part of fermented foods with specially added active live cultures; such as in yogurt, soy yogurt, or as dietary supplements. • Probiotics are thought to beneficially affect the host by improving its intestinal microbial balance, thus inhibiting pathogens and toxin producing bacteria. • Today, specific health effects are being investigated and documented including alleviation of chronic intestinal inflammatory diseases, prevention and treatment of pathogeninduced diarrhea, urogenital infections,and atopic diseases. • Colon is the most densely populated region of the gastrointestinal tract and harbors an estimated 500 different bacterial species. • The various types of bacteria that are having the probiotics characteristics are• Lactobacilli (Lactobacillus rhamnosus Lactobacillus reuteri Lactobacillus casei ) • Bifidobacterium breve • Streptococcus Probiotics are available in foods and dietary supplements • for example, • capsules, • tablets, and • Powders Examples of foods containing probiotics are • yogurt, • fermented and • unfermented milk, • some juices • soy beverages. • In probiotic foods and supplements, the bacteria may have been present originally or added during preparation. • Most probiotics are bacteria similar to those naturally found in people's guts, especially in those of breastfed infants (who have natural protection against many diseases). Most often, the bacteria come from two groups, Lactobacillus or Bifidobacterium. Within each group, there are different species (for example, Lactobacillus acidophilus and Bifidobacterium bifidus), and within each species, different strains (or varieties). A few common probiotics, such as Saccharomyces boulardii, are yeasts, which are different from bacteria. • Uses for Health Purposes • There are several reasons that people are interested in probiotics for health purposes. • Friendly bacteria are vital to proper development of the immune system, to protection against microorganisms that could cause disease, and to the digestion and absorption of food and nutrients. • Each person's mix of bacteria varies. Interactions between a person and the microorganisms in his body, and among the microorganisms themselves, can be crucial to the person's health and well-being. • This bacterial "balancing act" can be thrown off in two major ways: • By antibiotics, when they kill friendly bacteria in the gut along with unfriendly bacteria. • Some people use probiotics to try to offset side effects from antibiotics like gas, cramping, or diarrhea. • Similarly, some use them to ease symptoms of lactose intolerance— a condition in which the gut lacks the enzyme needed to digest significant amounts of the major sugar in milk, and which also causes gastrointestinal symptoms. • "Unfriendly" microorganisms such as diseasecausing bacteria, yeasts, fungi, and parasites can also upset the balance. Researchers are exploring whether probiotics could halt these unfriendly agents in the first place and/or suppress their growth and activity in conditions like: Irritable bowel syndrome – Inflammatory bowel disease (e.g., ulcerative colitis and Crohn's disease) – Infection with Helicobacter pylori (H. pylori), a bacterium that causes most ulcers and many types of chronic stomach inflammation – Tooth decay and periodontal disease – Vaginal infections – Stomach and respiratory infections that children acquire in daycare – Skin infections • Another part of the interest in probiotics stems from the fact there are cells in the digestive tract connected with the immune system. One theory is that if you alter the microorganisms in a person's intestinal tract (as by introducing probiotic bacteria), you can affect the immune system's defenses. • What is it? • Kibow® Biotics is a proprietary and patented probiotics dietary supplement that has been scientifically formulated and clinically tested. Kibow® Biotics metabolizes nitrogenous waste that has diffused from the bloodstream into the bowel. • Nitrogenous wastes are utilized by Kibow® Biotics as nutrients. As probiotics grow and multiply, they consume more nitrogenous waste and therefore effectively help maintain healthy kidney function. • • Probiotics and Kidney Health • When these waste products accumulate in high concentrations in the blood, they become highly toxic and can cause severe damage to many organ systems if they are not properly excreted. • Due to the overloaded and impaired kidneys, a buildup of poisonous wastes occurs in the bloodstream. Certain probiotic microorganisms can utilize urea, uric acid and creatinine and other toxins as its nutrients for growth. They then multiply, thereby creating a greater diffusion of these uremic toxins from the circulating blood across the lining of the intestinal walls into the bowel. This increased microbial growth is excreted along with the feces (which is normally 50% microbes by weight). • Enteric toxin reduction technology uses probiotic organisms to transform the colon into a blood cleansing agent, which, with the aid of microbes, indirectly removes toxic wastes and helps eliminate them as fecal matter. Consequently, it is possible to maintain a healthy kidney function with the oral use of Kibow® Biotics. • The patented, proprietary probiotics in Kibow® Biotics have been clinically tested and shown to be safe, effective and free of serious side effects when taken for as long as six months.