HORMONE
BALANCE©
Introduction, Class 1 of 5
Young Living Connect, LLC
HISTORY
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1938: DES developed by Sir Charles Dodd, commonly
prescribed during pregnancy to prevent miscarriages or
premature deliveries
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5-10 million exposed from 1938 – 1971
9 out of 10 daughters of women who took DES had deformed
reproductive systems
50% would never conceive
One out of seven contracted a rare and often fatal cancer called
adenocarcinoma; Also linked to rare form of testicular cancer in
sons
1942: Premarin developed by Ayerst Laboratories
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Put on market one year AFTER study published in Cancer
Research
Reported: “Estrogen is a very important factor in cervical
carcinogenesis.”
HISTORY
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1970’s: Premarin considered gold standard for
hormone replacement
1975: Clinical studies reported link between
synthetic horse estrogen in Premarin and uterine
cancers.
 Wyeth-Ayerst
required by FDA to put black-box
warning on package inserts
 Many believed it should have been pulled from the
market!
 *****Changed their tactics: Premarin (synthetic
estrogen) + Progestin, also known as Provera
(synthetic progesterone)
 Called it PREMPRO
HISTORY
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1993-1998: NIH drug trial: Women’s Health
Initiative, 16,608, 50-79 y/o women participated
2000-2001: Data and Safety Monitoring Board
(DSMB) found no statistical problems and to
continue the study
2001: National Cancer Institute and NIH: opinion
dramatically contrasted above
2002: Abruptly ended study – found significant
invasive breast cancers
HISTORY
2002: Journal of American Medical
Association study published: 26%
increase in breast cancers
 2003: Women over 65 had increased risk
of dementia or Alzheimer’s on Premarin
 2004: Journal of the National Cancer
Institute: 54% increased risk of ovarian
cancer
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HRT vs. BHRT
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Bio-Identical Hormones: The Keys that Fit
Receptor site for progesterone does not
recognize estrogen or testosterone, only the
molecular structure of progesterone; Bioidentical hormones are identical to human
hormones, have 100% relative binding affinity
(RBA)…no side effects. They fit perfectly unlike
synthetic hormones.
Over 400 abstracts (studies) on safety and
efficacy of BHRT
Your Endocrine System

Cholesterol: single building block molecule from
which all hormones are derived; the body makes
hormones from nutrients with the help of
enzymes
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Pituitary and hypothalamus: regulate flow of all
hormones including estrogen, progesterone, and
testosterone. Also directly interacts with
neurotransmitters that regulate mood.
Your Endocrine System

Thyroid: (<97.8 hypothyroidism) produce TSH,
T3, T4 and thyroid peroxidase, known for
affecting weight

Adrenal glands: (<118 = adrenal fatigue)
produce hormones and regulate sympathetic
nervous system; secrete 3 hormones in
response to stress: adrenaline, cortisol, DHEA
(anti-aging hormone)
Sex Hormones

Estrogen
 Develop
female sex organs
 Develop secondary sex characteristics
 Maintain menstrual cycle
 Support growth and function of uterus
 Moisturize vagina and cervix
 Stimulate cell growth
Sex Hormones
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Progesterone
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maintain uterus and
prepare it for pregnancy
promote survival of egg
once fertilized
stimulate bone building that
can prevent or treat
osteoporosis
act as natural diuretic
serve as natural
antidepressant
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Progesterone
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foster calming effect on
body
Maintain libido
promote regular sleep
patterns
oppose estrogen’s
predisposition to promote
cell growth so as to provide
protection against uterine,
breast and ovarian cancer
as well as fibrocystic
disease
Sex Hormones

Testosterone
 Boost
sex drive
 Support feelings of
arousal
 Promote sense of wellbeing
 Promote muscle
strength and healthy
body composition

Testosterone
 Increase
energy levels
 Increase body hair
production
 Improve bone density
 Produce enlargement
of penis and testes, as
well as the clitoris
HORMONES
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DHEA
 Body’s
most abundant circulating hormone
 DHEA production peaks by age 25
 Drops dramatically each year thereafter
 By age 70 most people’s DHEA levels have declined
by over 80%, leading to hormonal imbalances that
can affect quality of life
 These kinds of imbalances also occur with other
critical hormones in our aging bodies such as
testosterone, estrogen, and progesterone
www.lef.org
AGING

Premenopause, mid
30’s
 Almost
all women are
estrogen dominant
 DHEA drops 10%
every decade after 30
years old
 Decline correlated with
degenerative changes
such as heart disease,
cancer and
osteoporosis
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Perimenopause, mid
40’s
 Progesterone
declines
even more significantly
while estrogen
becomes sporadic with
high peaks.
 Testosterone drops
 Decreased sex drive,
energy, muscle tone,
 Thinning of vaginal
wall
AGING
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Menopause, late 40’s50’s
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Hasn’t had cycle for at
least 12 months
Not disease, just natural
transition
Affects all sex hormones
Still continue to produce
estrogen in ovaries
Adrenal glands and body
fat perpetuating estrogen
dominance
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Post Menopause
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Progesterone drops to
almost zero
Some cases ovaries
continue to produce
significant amount of
testosterone;
Some estrogen from
adrenal glands and body
fat
Frequently estrogen
dominant which is risk for
breast or uterine cancer
Hair loss, weight gain,
wrinkly skin, urinary
incontinence, low sex drive,
heart disease and
osteoporosis
AGING
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Andropause
 Decline
in testosterone, progesterone and
DHEA
 Increase in estrogen (estradiol)
 Believed by late John Lee, MD to be primary
cause of prostate enlargement and cancer
Vicious Cycle of Hormone
Imbalance
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Chronic stress
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Adrenal produce
adrenaline and
cortisol…too much too long
Destroy healthy muscle
and bone
Slows healing and normal
cell regeneration
Impairs digestion
Dulls mental processes
Interferes with healthy
endocrine function and
weaken immune system
Gain abdominal fat
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Body Fat
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Body fat is bad for
hormone balance
Conversely non balanced
estrogen and progesterone
predisposes you to gain
weight.
Fat cells produce even
more estrogen
Vicious Cycle of Hormone
Imbalance
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Synthetic hormone
drugs
Phytoestrogen
 Found
to be potent
anti-thyroid agents and
add estrogen
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Hormonal pollutants
 Chlorine
and fluoride
in tap water ultimately
raises estrogen
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Birth control pills
Vicious Cycle of Hormone
Imbalance
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Phthalates: chemicals
that soften plastic
Toxic to reproductive
system
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Found in toys
New shower curtain smell
Medical supplies (IV tubes
and bags)
Plastic food wrapping
Fragrances
Scented candles
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Phthalates
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Air fresheners
Fabric softeners
Perfumes
Nail polish
Soft plastics our food is
wrapped in (frozen pizzas)
Plastic water bottles
Vicious Cycle of Hormone
Imbalance
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Xenoestrogens “foreign”
Endocrine Disruptor Chemicals
Estrogen Mimicking Molecules
 Pesticides
 Herbicides
 Plastics
 Fuels
 Car exhausts
 Drugs
 Hygiene products
 Room deodorizers
 Meats
 Dairy products.
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Affects reproductive, cognitive,
thyroid, metabolism, digestion,
hormone balance
 Gender bent fish and frogs;
known for 10 year; sperm
count decreased by 50%
 Fibroid cysts, cancer –
Xenoestrogens cause cells
to duplicate quickly
 Heart disease – causes
arteriosclerosis (hardening)
 Past 60 years of chemicals;
hormonal pollutants,
steroids excreted by
humans using HRT, birth
control, agricultural run off,
plastics, pesticides
ESTROGEN DOMINANCE
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Estrogen promotes cell proliferation…Progesterone
inhibits cell proliferation!
Increases risk of chronic diseases including cancer,
cardiac disease, stroke and Alzheimer’s
Breast cancer patients show higher estrogen levels than
those without breast cancer
Creates abdominal weight gain…fat cells produce even
more estrogen
Linked to migraine headaches, anxiety disorders,
insomnia and decreased mental acuity
No woman with or without a uterus or ovaries should
ever take estrogen of any kind alone!
PROGESTERONE…to the rescue
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Research: Funded by AHA, International Journal
of Pharmaceutical Compounding; BHRT of
progesterone was shown to relieve menopausal
symptoms without compromising cardiac or
vascular health.
2005 study in International Journal of Cancer;
Progesterone actually decreases risk of breast
cancer by 10%!
Several studies showing progesterone is cancer
protective, anticarcinogenic properties
Studies validate progesterone has cardioprotective effect
PROGESTERONE…to the rescue
Stimulates osteoblast cells…bone
formation cells that result in new bone
growth
 Using transdermal progesterone had
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 7-8%
increase in bone density in first year
 4-5% second year and
 3-4% third year
PROGESTERONE…to the rescue
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Resolves PMS symptoms in 83% women
included in study
Tempers insulin release, normalizing blood
sugar levels, thereby reducing food cravings
Increases sex drive
Improves quality of life: reduces sleep disorders,
hot flashes, anxiety and symptoms of depression
BOOST ADRENAL SYSTEM
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Stress less, rest more
 Exercise
 The
Relaxation Response, Dr. Benson of
Harvard Medical School
 10-20 minutes daily, close eyes, breathe in
deeply nose, say “one”, then breathe out, say
“one”
 Yoga
BOOST ADRENAL SYSTEM
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Eat to eliminate extra estrogen
 Cruciferous
veggies: broccoli, asparagus, cauliflower,
spinach, celery, brussel sprouts, kale, cabbage,
radish, turnip, collard and mustard greens
 Citrus fruits (D-limonene): promotes detoxification of
estrogen…and lowers weight
 Insoluble fiber: (binds estrogen to it) whole grains,
whole wheat breads, barley, couscous, brown rice,
wheat bran, seeds, carrots, cucumbers, zucchini,
celery, tomatoes
 Lignans: ground flaxseed, sesame seeds, flaxseed oil
 Eat organic
BOOST ADRENAL SYSTEM
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Supplements
B
Vitamins
 Vitamin E
 Calcium-Magnesium combo: ratio of 1,500 mg. Ca+
to750 mg. Mg+
 DHEA
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Go green
 Avoid
plastics, check labels, and buy pure soaps and
toothpastes and other personal care products
WHAT YOU CAN DO
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Progessence Cream (Natural Progesterone);
rub ¼ tsp to body am and pm
Prenolone + Cream (Natural Pregnenolone,
Progesterone & DHEA) apply same as above
Endogize; men 2 tab 3X daily, women 1 tab 3X
daily
EndoFlex; dilute 1:1 and apply to lower back,
thyroid, kidneys, liver, feet, glandular areas;
diffuse 30 minutes 3X daily, may take as dietary
supplement, dilute with V-6 and take up to 3X
daily
WHAT YOU CAN DO
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UltraYoung Oral Spray; 3 sprays in mouth
Sulfurzyme and Super C taken together work
synergistically to restore flexibility of
vessels/cells
Thyroid specific: if after 3 months on Endogize,
if temp. below 97.8 then take 2 Thyromin at
bedtime (if taken in morning works on
adrenals)
RESOURCES
Newsletter: www.hormonewell.com
 Newsletter:
www.virginiahopkinstestkits.com
 Testing: www.mymedlab.com
 Salivary and Blood Spot Testing
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 ZRT
Laboratory: www.salivatest.com
 503-466-2445
RESOURCES
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Life Extension® offers low cost blood test
panels
To order a comprehensive Male or Female
Blood Test Panel, call 1-800-208-3444
Once you receive your blood test results,
you can take them to your doctor or talk to a
Life Extension Health Advisor at:
1-800-226-2370
RECOMMENDED READING
Young, D. Gary. Pregnenolone, A Radical
New Approach to Health Longevity, and
Emotional Well-being.
 Lee, John R. Natural Progesterone, The
Multiple Role of a Remarkable Hormone
 Lee, John R., with Virginia Hopkins. What
Your Doctor May Not Tell You About
Menopause.
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Statements with claims have not been evaluated by the Food and Drug Administration.
This information is not intended to diagnose, treat or prevent any disease.