DYSPHAGIA FAISAL GHANI SIDDIQUI MBBS; FCPS; MCPS (HPE); PGD (BIOETHICS) faisal@lumhs.edu.pk www.lumhs.edu.pk/faculties/surgery/gsurgery/about-dr.faisalghani.html PREAMBLE DYSPHAGIA & ITS TYPES? NORMAL SWALLOWING REFLEX DIAGNOSTIC PROTOCOL DYSPHAGIA DIFFICULTY IN SWALLOWING RESULTS FROM ANY PATHOLOGY THAT INTERFERES WITH THE NORMAL SWALLOWING MECHANISM SWALLOWING REFLEX -3 PHASES ORAL PHARYNGEAL OESOPHAGEAL ORAL PHASE FOOD BOLUS ROLLED BACK BY THE TONGUE INTO THE PHARYNX PHARYNGEAL PHASE FOOD PASSES THROUGH THE PHARYNX INTO THE OESOPHAGUS OESOPHAGEAL PHASE FOOD PASSES THROUGH THE OESOPHAGUS INTO THE STOMACH TYPES OF DYSPHAGIA HIGH (OROPHARYNGEAL) DYSPHAGIA OCCURING AT OR ABOVE CRICOPHARYNGEUS LOW (OESOPHAGEAL) DYSPHAGIA OCCURING BELOW CRICOPHARYNGEUS DYSPHAGIA -CAUSES HIGH (OROPHARYNGEAL) DYSPHAGIA NEUROLOGICAL / NEUROMUSCULAR • • • • • MECHANICA / STRUCTURAL • PHARYNGEAL POUCH • TUMOURS CVA PARKINSON’S DISEASE MULTIPLE SCLEROSIS MYSTHAENIA GRAVIS BULBAR / PSEUDOBULBAR PALSY DYSPHAGIA -CAUSES LOW (OESOPHAGEAL) DYSPHAGIA PRIMARY MOTILITY DISORDERS • ACHALASIA • DIFFUSE OESOPHAGEAL SPASM • NUTCRACKER OESOPHAGUS SECONDARY MOTILITY DISORDERS MECHANICAL (INTRINSIC DISEASES) • CHAGA’S DISEASE MECHANICAL (EXTRINSIC DISEASES) • • • • • OESOPHAGEAL CARCINOMA • BENIGN STRICTURE BRONCHOGENIC CARCINOMA THORACIC AORTIC ANEURYSM GOITRE DYSPHAGIA LUSORIA DYSPHAGIA -DIAGNOSIS HISTORY PHYSICAL EXAMINATION INVESTIGATIONS HISTORY HIGH (OROPHARYNGEAL) DYSPHAGIA ASSOCIATED WITH CHOKING OR COUGHING IMMEDIATELY AFTER SWALLOWING SWALLOWING SOLIDS EASIER THAN LIQUIDS HISTORY DYSPHAGIA DUE TO OESOPHAGEAL CARCINOMA SHORT DURATION (< 3 MONTHS) PROGRESSIVE ASSOCIATED WEIGHT LOSS HISTORY DYSPHAGIA DUE TO MOTILITY DISORDERS LONG HISTORY INVOLVES BOTH SOLIDS AND LIQUIDS DYSPHAGIA MAY DISAPPEAR, BEING REPLACED WITH REGURGITATION & NOCTURNAL COUGH PHYSICAL EXAMINATION OFTEN UNREWARDING MOVEMENTS OF TONGUE, PALATE, & MUSCLES OF FACIAL EXPRESSION CERVICAL LYMPHADENOPATHY WEIGHT LOSS INVESTIGATIONS ENDOSCOPY BARIUM SWALLOW MANOMETRY EUS ENDOSCOPY PATIENTS WITH HIGH DYSPHAGIA WITH NO OBVIOUS NEUROLOGICAL CAUSE SHOULD BE REFERRED TO ENT SPECIALIST FLEXIBLE LARYNGOSCOPY FLEXIBLE NASOENDOSCOPY RIGID ENDOSCOPY ENDOSCOPY OESOPHAGEAL DYSPHAGIA BIOPSIES TO DIFFERENTIATE MALIGNANT & BENIGN STRICTURES THERAPEUTIC; DILATATION OF BENIGN STRICTURES / MOTILITY DISORDERS STENTING IN INOPERABLE TUMOURS BARIUM SWALLOW OESOPHAGEAL DYSPHAGIA Demonstrates different structural pathologies Hiatus hernia | Strictures Achalasia | Tumours MANOMETRY PATIENTS WITH NO STRUCTURAL ABNORMALITY ON ENDOSCOPY REQUIRE FURTHER INVESTIGATION WITH MANOMETRY TO EXCLUDE MOTILITY DISORDERS ENDOSCOPIC ULTRASOUND USED FOR STAGING OF HISTOLOGICALLY PROVEN OESOPHAGO-GASTRIC CARCINOMA WALL PENETRATION LYMPH NODE INVOLVEMENT EXTRINSIC OESOPHAGEAL COMPRESSION HIGH DYSPHAGIA HISTORY SUGGESTIVE OF NEUROLOGICAL CAUSE NO ENT REFERRAL OROPHARYNGOLARYNGOSCOPY YES VIDEOFLOUROSCOPY & MANOMTERY