Ethical Dilemmas in HIV Wendy Majewska Senior Health Adviser St George’s Hospital London Ethics Hippocrates considered to be father of western medicine and contributed to establishing medicine as a profession Hippocratic Oath seminal document on the ethics of medical practice rarely used in its original form today although serves as foundation for other similar oaths and laws that define good medical practice Four guiding principles Pillars of ethics Non-maleficence Beneficence Justice Autonomy Ethical dilemmas? Fertility treatment Organ donation End of life care HIV…… Terminal Sexually transmitted Case 1 16 year old HIV positive female Sexually active Aware safer sex stated ‘uses condoms’ Brought male partner to clinic reporting ‘condom broke’ Requested PEPSI Male partner unaware of HIV status Patient did not want partner to know her HIV status Can PEPSE be given without disclosing HIV status? Should confidentiality be broken and HIV status disclosed? Influencing factors Risk of transmission 1:1000 -1:3000 VL Length of exposure Potential harm Case 2 32yr old gay man diagnosed HIV+ PN RMP 4 years Tested HIV+ RMP – PN Married 26 years - midwife Reluctant to inform – reported no recent SI Influencing factors Sexual history VL / CD4 count On-going risk Occupation Co-habiting Time frame Collaborative working Case 3 17 year old female Tested HIV positive through TOP service Came to UK aged 15 Foster care Pt felt likely to be infected vertically Did not want mother to know HIV status Can we inform mother? Can we withhold daughter’s HIV status? Case 4 HIV+ newly diagnosed woman Unusual drug resistance assay Seen by consultant working at 2 sites Recognised resistance pattern Clarified risk factors Female pt at other clinic same resistance pattern – similar profile of sexual contact identified Additional female patient identified – address noted as being the same as 1st pt PN – contact identified - attended neighbouring hospital (KH) with TB HA contacted KH clinic Man identified - HIV+ lost to follow up PN at KH identified 16 year old female HIV+ Index male patient diagnosed prior to sexual contact with 4 female HIV patients History from all 4 female pts indicated no condom used None of the 4 females knew of each other HIV+ man knowingly exposed 4 women to HIV infection Can action be taken? What action might be appropriate? Case 5 Pregnant woman Declined HIV testing in pregnancy Referred to HIV Midwife Referred to Health Adviser Issues re unborn baby Is safeguarding of unborn child an issue? Would the same apply across UK? On-going ethical issues Pregnant – refusing ART Contact of HIV+ refusing testing but in other steady relationship Paediatric HIV - YP MTCT Confidentiality Key points Decision should not be taken alone Work as MDT Remember Non-maleficence Beneficence Justice Autonomy Health Advisers are key in exploring ethical issues resolution of dilemmas If not us, WHO? HIV and the law Offences Against the Person Act 1861 Sections of the OAPA 1861 ‘grievous bodily harm’ Two possible offences ‘reckless transmission’ (section 20) ‘intentional transmission’ (section18) • To date not yet been a successful prosecution for intentional transmission 14 prosecutions to date in E&W 9 pleaded ‘guilty’ 5 pleaded ‘not guilty’ 2 convicted longest sentence 10 years – 3 complainants other sentences range 2 - 4 and half years 2 convictions were in women Intentional Or Reckless Sexual Transmission Of Infection ‘….this area of the criminal law is exceptionally complex’ ‘….will be difficult to prove to the requisite high standard…’ There are other sensitivities: the relationship between the criminal law and consensual sexual behaviour is delicate. The use of the criminal law in the most intimate of physical exchanges is always going to attract publicity and will invite strongly held and differing views Intentional Or Reckless Sexual Transmission Of Infection Guidance Crown Prosecution Service