5th Inter-Agency Meeting on Coordination and Harmonization of HIV/AIDS, TB and Malaria Strategies Brazzaville, Congo 5-7 March 2014 Treatment 2015 launch The agreed target… .. and focusing on treatment is strategic Treatment continues to expand 15 0 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2003 2012 2013 20142015 2015 Gaps in global antiretroviral coverage under the 2010 and 2013 WHO HIV treatment guidelines Total eligible: 14,000,000 28,600,000 100% 50% *Numbers of people receiving treatment in December 2012 versus 39% (a) the numbers eligible in December 2012 under the 2010 WHO guidelines; (b) the numbers eligible in December 2013, under the 2013 WHO guidelines. 0% 2010 guidelines* Eligible and receiving treatment Eligible but not receiving treatment 66% 18,563,000 2013 guidelines* Gap in antiretroviral coverage varies within Africa Source: UNAIDS estimates 2013 The agreed target is still ambitious… …and is a stepping stone towards treatment for all in need UNAIDS PCB calls for new targets • • • • Encompass new science Drive progress Guide action beyond 2015 Ultimately aspire to end the AIDS epidemic Challenges ahead: 1- Societal • • • Lack of knowledge of HIV status Punitive policies and laws Stigma and discrimination Challenges ahead: 2- diverse facility level costs $1,200 Maximum $1,000 $800 Average US$ US$682 $600 Minimum $400 US$278 US$232 $200 US$186 US$136 $0 Malawi Ethiopia Rwanda Zambia *Republic of South Africa: costs include updated antiretroviral prices, which were renegotiated by the RSA government in early 2010 and are 53% lower than those observed during the costing period. RSA South Africa* Challenges ahead: 3- treatment cascade Notes: No systematic data are available for the proportion of people living with HIV who are linked to care, although this is a vital step to ensuring viral suppression in the community. Sources: 1. UNAIDS 2012 estimates; 2. Demographic and Health Surveys, 2007–2011 (www.measuredhs.com); 3. Kranzer, K., van Schaik, N., et al. (2011), PLoS ONE; 4. GARPR 2012; 5. Barth R E, van der Loeff MR, et al. (2010), Lancet Infect Disease. Challenges ahead: 4- delivery systems Relative likelihood of HIV-positive adults (15-49 years) accessing antiretroviral therapy due to the distance from their nearest primary healthcare facility. Source: Location, Location: Connecting people faster to HIV services, UNAIDS; Geneva, 2013 Challenges ahead: 5- Key populations and partners a substantial share of new infections Nigeria Kenya Mozambique Morocco Dominican Rep. Peru 51% about 33% more than 25% 80% 47% 65% HIV treatment can normalize survival Expected impact of HIV treatment in survival of a 20 years old person living with HIV in a high income setting (different periods) What we can achieve Projected annual AIDS-related deaths, assuming scale up to 95% coverage by 2020 Expanding access to ART is a smart investment: Case of South Africa Source: Expanding ART for Treatment and Prevention of HIV in South Africa: Estimated Cost and Cost-Effectiveness 2011-2050. PLoS ONE 7(2):e30216 ART costs as a percentage of GDP With international support, universal access to ART is at reach in low- and middle income countries Malawi Lesotho Zimbabwe Mozambique Burundi Uganda Central African Rep. Tanzania Zambia Swaziland Kenya Liberia Togo Rwanda Sierra Leone Cameroon Chad Guinea-Bissau Côte d’Ivoire Botswana Haiti Guinea Namibia Djibouti Nigeria South Africa Burkina Faso Niger Benin Eritrea Ghana Mali Cambodia Belize Myanmar Senegal 5% – 8% 2% – 5% 1% – 2% 0.1% – 1% 0 1 2 3 4 Source: Williams arXiv 2012: http://arxiv.org/abs/1206.6774 5 6 7 8% The tasks ahead Develop instruments (to support partners) Modelling Costing Supply forecast Testing campaign Consultations (Countries, regions, ad hoc) Country consultations Regional consultations Dialogue with key strategic partners Global consensus meeting Monitoring and evaluation Demand Resources Progress Source: Terhorst, D & Schmid, G., WHO 2006 Making it work: The African Union Roadmap • • • Sustainable financing models Access to medicines – Local production and regulatory harmonization Leadership, governance and oversight