The impact of latent confounders in directed network analysis in neuroscience by Rebecca Ramb, Michael Eichler, Alex Ing, Marco Thiel, Cornelius Weiller, Celso Grebogi, Christian Schwarzbauer, Jens Timmer, and Björn Schelter Philosophical Transactions A Volume 371(1997):20110612 August 28, 2013 ©2013 by The Royal Society (a) The results of the rPDC estimation based on simulated data of the four-dimensional VAR process of order 2 given by equation (3.1). Rebecca Ramb et al. Phil. Trans. R. Soc. A 2013;371:20110612 ©2013 by The Royal Society The associated Granger causality graph of the four-dimensional VAR is depicted in (a), and the associated graph when the fourth component is disregarded is shown in (b). Rebecca Ramb et al. Phil. Trans. R. Soc. A 2013;371:20110612 ©2013 by The Royal Society (a) The results of the rPDC analysis of the nonlinear system consisting of four coupled Roessler systems. Rebecca Ramb et al. Phil. Trans. R. Soc. A 2013;371:20110612 ©2013 by The Royal Society The multivariate rPDC analysis of the data generated by the autoregressive process for the directed path of type 1. Rebecca Ramb et al. Phil. Trans. R. Soc. A 2013;371:20110612 ©2013 by The Royal Society The multivariate rPDC analysis of the data generated by the coupled Roessler system for the directed path of type 1. Rebecca Ramb et al. Phil. Trans. R. Soc. A 2013;371:20110612 ©2013 by The Royal Society The graph associated with the multivariate analysis of influence type 1 is shown in (a). Rebecca Ramb et al. Phil. Trans. R. Soc. A 2013;371:20110612 ©2013 by The Royal Society The multivariate rPDC analysis of the nonlinear time-series data for the directed path of type 2 in (a), and the bivariate analysis of components one and three in (b). Rebecca Ramb et al. Phil. Trans. R. Soc. A 2013;371:20110612 ©2013 by The Royal Society The graph of the multivariate analysis is displayed in (a). Rebecca Ramb et al. Phil. Trans. R. Soc. A 2013;371:20110612 ©2013 by The Royal Society The graph of the multivariate analysis in (a) versus the bivariate graph in (b), in the case of type 3. Rebecca Ramb et al. Phil. Trans. R. Soc. A 2013;371:20110612 ©2013 by The Royal Society The rPDC analysis of the nonlinear system containing an additional reciprocal connection for all components (a) and components one and three (b). Rebecca Ramb et al. Phil. Trans. R. Soc. A 2013;371:20110612 ©2013 by The Royal Society The associated graph of the initial four-dimensional VAR in (a), together with its corresponding bivariate graph in (b). Rebecca Ramb et al. Phil. Trans. R. Soc. A 2013;371:20110612 ©2013 by The Royal Society