Impulse oscillometry By Dr/ Hossam EL-din mohamed Lecturer of chest diseases Ain Shams university At the end of this lecture you would be able to: • List the different components of IOS. • Interpret IOS results. • Compare the variations in IOS results among different disease states. • Describe the limitations of IOS. • Describe the assessment of bronchial hyperreactivity using IOS. Impulse oscilomety (IOS) Ohm‘s Law: Resistance = pressure flow AIRWAY RESISTANCE • The relationship between pressure and flow tells us about airway resistance. Flow Pressure Low Resistance High Resistance IOS Methods of measurement of airway resistance • Occlusion technique • Impulse oscillometry • Bodyplethysmography OCCLUSION occlusion pressure PT flow Forced Oscillation Technique (FOT): • Apply frequencies from outside to the airways • measure pressure changes • Range: from 1 Hz to 30 Hz One frequency Two frequencies Sum of two frequencies Rectangular pulse: all frequencies Simplified approach: • pressure waves generate pressure in the lungs • waves are reflected in the lungs • reflected waves carry information about the pressure at different places in the lungs • flow measured via PT • reflected waves are analysed in respect of pressure and frequency • Resistance = pressure/flow • can be calculated for different frequencies (= areas) Different Frequencies • High frequencies: low penetration upper (central) airway • Low frequencies: deep penetration total airways (central and peripheral) Impulse Penetration Slow Impulses 5Hz Fast Impulses 20 Hz Impedance Z = R + jX Impedance describes a complex (mathematical sense) airway resistance which includes two components, the real resistance R and the imaginary reactance X. Reactance X (Capacitive-inertial storage of energy) Reactance consists of two components. The positive inertial portion increases with frequency and the negative capacitive portion decreases frequency X at 5 Hz: X5 Distal capacitive reactance f at X=0: Fres Resonant frequency The ability to store energy in the capacitance (elastic recoil) is prerequisite for passive expiration. Inertance has minor clinical relevance Impedance Z Respiratory impedance, i. e. the interaction between resistive and reactive properties of the respiratory system, is primarily measured by the oscillometric method.