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www.labthroughput.com
©
845-425-9711
845-270-8449
1
LTP is a software company dedicated to improving
workflow efficiency and productivity in the clinical
laboratory
LTP Products:




Automate results verification, review, follow-up actions
and disposition for Hematology, Coagulation, Chemistry
& Immunochemistry, and Urinalysis
Optimize by monitoring workflow in real-time and
retrospectively
Provide real-time Quality Control compliance
Allow you to expand your hematology services to
automate BAL and other fluid analyses
©
2
 What
LTP does
 How LTP works
 How the LTP review-criteria optimization
process works
 How
LTP reduces operating
costs/improves profitability
 What
LTP products are available
©
3
LabThroughPut
™
GlobaLab Efficiency Products
LTP ACHIEVER™
LTP OPTIMIZER™
LTP QC SENTINEL™
LTP BAL/HEMATOLOGY™
LTP MIDDLEWARE™ SYSTEM Configuration
©
4
LTP GlobaLab ™ Products
LTP ACHIEVER™
LTP
HEMATOLOGY™
LTP
COAGULATION™
LTP CHEMISTRY™
LTP URINALYSIS™
LTP OPTIMIZER™
LTP
HEMATOLOGY™
LTP
COAGULATION™
LTP CHEMISTRY™
LTP URINALYSIS™
LTP QC SENTINEL™
LTP BAL/HEMATOLOGY™
©
5
LTP ACHIEVER™
LTP ACHIEVER is a system that optimizes results
processing in the laboratory and improves productivity

ACHIEVER MODULES
◼
SYSTEM SETUP and SECURITY
◼
INSTRUMENT MANAGER
◼
EVALUATOR
◼
PROCESSOR
◼
ENDSHIFT
◼
MONITOR
©
6
LTP ACHIEVER™
LTP ACHIEVER is a system that optimizes results
processing in the laboratory and improves productivity

ACHIEVER MODULE Functionality
◼
SYSTEM SETUP and SECURITY
 Provides for Defining: access level heirarchy, user/password
control, parameters, review rules, edit/display order, and Shift
report content and distribution
◼
INSTRUMENT MANAGER
 Controls data transmission: receives data from analyzers and
LIS, transmits to analyzers and LIS; monitors connectivity
◼
EVALUATOR
 Evaluates results by autoverification of User Rules: assigns
samples to worklists and locates them for tech data entry
screens, provides disposition of results
©
7
LTP ACHIEVER™
LTP ACHIEVER is a system that optimizes results
processing in the laboratory and improves productivity

ACHIEVER MODULE Functionality

PROCESSOR
 Provides for all operations: label printing, data
entry/modification, Supervisory review/approval, tracks current
status and audit trail of results, and provides for archive and
retrieval

ENDSHIFT
 Closes Instrument Manager at defined end of shift times;
creates, distributes and saves End of Shift Reports

MONITOR
 Checks Instrument Manager and Evaluator continually, in the
background, for proper functioning of data entry/modification
©
8
LTP ACHIEVER™
WHAT LTP ACHIEVER DOES

LTP ACHIEVER is a complete results
processing system.
◼
◼
◼
◼
◼
◼
◼
◼
Auto-verifies analyzer results
Issues follow-up worklists along with procedures
Provides data entry screens for necessary results
changes
 On-screen diffpad for microscopic observation entry
Determines final disposition
Transmits results to the host computer system for
release
Stores every state of every specimen record in a
database; maintains audit trail
Self-monitors and diagnoses system operations
Produces activity and productivity reports
©
9
LTP ACHIEVER™
SYSTEM SETUP & SECURITY MODULE
Functions

User-definable setup of:
Review Rules
 Instrument and Lab-defined parameters to receive
 Parameters to be displayed/edited by techs, including
display order
 Parameters to be transmitted to LIS
 User names/passwords
 Access levels to system functions
 Shift Report contents and E-mail recipients

Features


©
User defines which parameter value fields can be
edited by tech, and under which circumstances
Parameter field background colors are userdefinable for clarity
10
LTP SYSTEM SETUP SCREENS
©
LTP SYSTEM SETUP REVIEW CRITERIA REPORT
©
LTP ACHIEVER™
INSTRUMENT MANAGER MODULE
Functions


Receives data from analyzers and LIS
Transmits data to analyzers and LIS
Features


Analyzer/Instrument Manager connectivity
diagnostics
Host/Instrument Manager connectivity
diagnostics

Issue connectivity alerts audibly, via E-mail and via text
messaging
©
13
LTP INSTRUMENT MANAGER SCREEN
©
LTP ACHIEVER™
EVALUATOR MODULE
EVALUATOR Features:



Follow-up procedure worklists are created based
on User criteria
Special follow-up options include automatic
replacement of instrument parameter values by
values obtained on the instrument by other
means; e.g. WIC/WOC or analyte dilution results
Audit trail maintenance:
Database archival of up to 1,000,000 specimen records
 Every state of every record is stored in a database
 All changes made to results are recorded/audit trailed

– WHO, WHEN and WHY any change was made
– WHAT Method used to make the change

©
Final disposition state for each specimen record
is recorded
15
LTP EVALUATOR MODULE SCREEN
©
LTP ACHIEVER™
PROCESSOR MODULE
PROCESSOR Features:

Open architecture supports simultaneous
analysis of any combination of:
 Multiple Species
 Analyzer manufacturers/models
 Body fluid types

Analyzes specimen results on-line in real-time,
using your verification criteria.
 Special verification options include:
–
–
–
–
Activation/de-activation of individual rules within a set
Advanced delta-check techniques
Color coding for: Rerun, Diff needed, Spun Hct
Tech ID, data entry, results and workstation tracked
©
17
LTP ACHIEVER™
ENDSHIFT MODULE
Endshift Features

The Endshift process is entirely automatic
Stops Instrument Manager and Evaluator automatically
 Restarts Instrument Manager and Evaluator
automatically when Endshift process is completed






©
Endshift Report contents and recipients are User
definable
Endshift will not occur if LTP detects that
specimens are still being processed
Endshift times can vary by day and shift
Multiple Endshifts per day can be programmed
Number of Endshift retries and retry intervals are
user definable
18
LTP ACHIEVER™
MONITOR MODULE
MONITOR Features:




Monitors Evaluator and Instrument Manager for
functional compliance
Starts automatically at beginning of shift and runs
in the background
Restarts application(s) if fault is detected
Maintains an all inclusive event Log
©
19
LTP MONITOR MODULE SCREEN
©
LTP OPTIMIZER™
WHAT LTP OPTIMIZER DOES

LTP OPTIMIZER ™ helps you optimize
specimen results throughput in the laboratory

Uses your results-verification criteria to measure
the overall specimen-result review rate in the
laboratory
 Determines the frequency of follow-ups based on
each criterion, and the frequency of each follow-up
procedure; eg. analyzer reruns or manual
differentials
 Allows readjustment of criteria and re-analyzes the
results to optimize criteria and improve throughput
 Provides database query capability
©
21
LTP OPTIMIZER™
WHAT LTP OPTIMIZER DOES
OPTIMIZER Features
 LTP OPTIMIZER™ provides review rates:
 For all specimens combined
 Based on individual review criterion
 Based on instrument, for multiple-instrument
systems
 Based on instrument model, for labs using more
than one analyzer model (open architecture)
 Based on body fluid type, for labs running whole
blood samples and other body fluids
 Based on species, for veterinary labs
©
22
LTP OPTIMIZER™
LTP OPTIMIZER QUERY MODULE
Functions

Queries either the live or archival database for
performance parameters
Productivity summary by analyzer or by operator
 # of specimens analyzed over time interval per species,
analyzer, tech, body fluid type, etc.
 # of specimens work-listed per rule, per species, per
analyzer, per body fluid type
 # of follow-up actions per rule, per species, per analyzer,
per body fluid type

Features


©
Analysis of archived results based on rules applied
live
Analysis of archived results using modified review
rules
23
LTP ACHIEVER/HEMATOLOGY™
WHAT LTP ACHIEVER/HEMATOLOGY™ DOES
 LTP ACHIEVER/HEMATOLOGY is a complete
results processing system.






Auto-verifies hematology analyzer results
Issues follow-up worklists along with procedures
Provides data entry screens for necessary results
changes
 On-screen diffpad
Determines final disposition
Transmits results to the host computer system for
release
Stores every state of every specimen record in a
database
©
24
LTP HEMATOLOGY™
HOW the LTP review-criteria optimization
process works
SETUP REVIEW CRITERIA & SECURITY
 ENTER (AND EDIT) REVIEW CRITERIA



REVIEW-CRITERIA BATCH SCREEN
REVIEW-CRITERION EDITOR
Review specimen record data
 Examine results of specimen record
review
 Edit review criteria and re-analyze data

©
25
LTP HEMATOLOGY™
SYSTEM SETUP & SECURITY MODULE
Functions

User-definable setup of:
Review Rules
 Instrument and Lab-defined parameters to receive
 Parameters to be displayed/edited by techs, including
display order
 Parameters to be transmitted to LIS
 User names/passwords
 Access levels to system functions
 Shift Report contents and E-mail recipients

Features


©
User defines which parameter value fields can be
edited by tech, and under which circumstances
Parameter field background colors are userdefinable for clarity
26
LTP HEMATOLOGY SYSTEM SETUP SCREENS
©
LTP HEMATOLOGY SYSTEM SETUP REVIEW CRITERIA REPORT
©
LTP HEMATOLOGY REVIEW CRITERION SETUP SCREEN
©
LTP HEMATOLOGY™
ENTER/EDIT REVIEW CRITERIA





Review criteria are grouped. A set (“batch”)
of criteria is entered for each combination of
instrument type/body fluid type/species (see
slide 12)
Multiple sets can be active simultaneously,
but only one set at a time can be active for
each combination of instrument type/body
fluid type/species
Sets and individual criteria can be deactivated
Specimens not matching any set are flagged
Sets can be printed
©
30
LTP HEMATOLOGY™
ENTER/EDIT REVIEW CRITERIA
Review criteria include
 Limits
Parameter values
 Products of 2 parameter values
 Ratios of 2 parameter values
 Sums of 2 parameter values
 Differences of 2 parameter values
 % differences of 2 parameter values

 Morphology
Flags
Presence
 Severity

 System
Operational Alerts
Presence
 Severity

©
(CONTINUED ON
NEXT SLIDE)
31
LTP HEMATOLOGY™
ENTER/EDIT REVIEW CRITERIA
Review criteria include:
 Demographics


Age
Gender
 Blanked results
 Delta Checks (Apply to any combination of parameters listed
above under limits)





Difference
Absolute difference
% difference
Absolute % difference
Rate of delta for any of the above, by:
– Day, Week or Month
©
32
LTP HEMATOLOGY REVIEW CRITERIA BATCH SCREEN
INSTRUMENT
TYPE
SPECIES
SPECIMEN
TYPE
©
33
LTP HEMATOLOGY REVIEW CRITERION EDITOR SCREEN
CRITERION
ACTION
PARAMETER THAT IS RE-ANALYZED
AFFECTED PARAMETER(S)
FORMULAS
©
34
LTP HEMATOLOGY REVIEW CRITERION EDITOR SCREEN
PARAMETER LIST
©
35
LTP HEMATOLOGY REVIEW CRITERION EDITOR SCREEN
MORPHOLOGY FLAG LIST
©
36
LTP HEMATOLOGY REVIEW CRITERION EDITOR SCREEN
SYSTEM OPERATIONAL ALERTS
©
37
LTP HEMATOLOGY REVIEW CRITERION EDITOR SCREEN
OPERATORS
©
38
LTP HEMATOLOGY REVIEW CRITERION EDITOR SCREEN
RELATIONAL
OPERATORS
©
39
LTP HEMATOLOGY REVIEW CRITERION EDITOR SCREEN
LIST OF ACTIONS
©
40
LTP HEMATOLOGY™
EVALUATOR MODULE
EVALUATOR Features



Follow-up procedure worklists are created based
on your criteria
Special follow-up options include automatic
replacement of instrument parameter values by
values obtained on the instrument by other
means; e.g. WIC/WOC
Audit trail maintenance:
Database archival of up to 500,000 specimen records
 Every state of every record is stored in a database
 All changes made to results are recorded/audit trailed

– WHO, WHEN and WHY any change was made
– WHAT Method used to make the change

Final disposition state for each specimen record
is recorded
©
41
LTP HEMATOLOGY EVALUATOR MODULE SCREEN
©
LTP HEMATOLOGY™
PROCESSOR MODULE
Functions

Provides for all operations: label printing, data
entry/modification, Supervisory review/approval,
tracks current status and audit trail of results, and
provides for archive and retrieval
Features





Auto-verifies analyzer results
Issues follow-up worklists along with procedures
Provides data entry screens for necessary results
changes
 On-screen diffpad or microscopic observation entry
Determines final disposition
Stores every state of every specimen record in a
database
©
43
LTP HEMATOLOGY™
PROCESSOR MODULE
PROCESSOR Features

Open architecture supports any combination of:
 Analyzer manufacturers/models
 Body fluid types
 Species

Analyzes specimen results on-line in real-time,
using your verification criteria.
 Special verification options include:
–
–
–
–
Activation/de-activation of individual rules within a set
Advanced delta-check techniques
Color coding for: Rerun, Diff needed, Spun Hct
Tech ID, data entry, results and workstation tracked
©
44
LTP HEMATOLOGY PROCESSOR SCREEN
©
LTP HEMATOLOGY PROCESSOR SCREEN
©
LTP HEMATOLOGY REVIEW SPECIMEN RECORD DATA SCREEN
MORE SPECIMEN
INFORMATION
©
47
LTP HEMATOLOGY REVIEW SPECIMEN RECORD DATA SCREEN
REVIEW RATE
BY ACTION
©
48
LTP HEMATOLOGY PROCESSOR SCREEN
©
LTP HEMATOLOGY™
ENDSHIFT MODULE
Functions
 Closes Instrument Manager
and Evaluator at
predetermined times during the day
 Creates shift reports that include
Overall workshift output
 Technologist productivity
 Analyzer outputs by table and graphical display
 Review rules analysis

 Saves
reports on system server and emails
reports to designated addresses
©
50
LTP HEMATOLOGY™
ENDSHIFT MODULE
Features




Endshift times can vary by day and shift
Multiple Endshifts per day can be programmed
Report contents and recipients are user definable
The Endshift process is entirely automatic
Stops Instrument Manager and Evaluator automatically
 Restarts Instrument Manager and Evaluator
automatically when Endshift process is completed



Endshift will not occur if LTP detects that
specimens are still being processed
Number of Endshift retries and retry intervals are
user definable
©
51
LTP ENDSHIFT REPORTED RESULTS
YOUR LAB
ADDRESS, ETC
©
LTP ENDSHIFT PENDING RESULTS
YOUR LAB
ADDRESS, ETC
©
LTP ENDSHIFT CUMULATIVE INSTRUMENT REPORT
YOUR LAB
ADDRESS, ETC
©
LTP ENDSHIFT INSTRUMENT MANAGER REPORT
YOUR LAB
ADDRESS, ETC
©
LTP ENDSHIFT INSTRUMENT MANAGER REPORT
YOUR LAB
ADDRESS, ETC
©
LTP ENDSHIFT INSTRUMENT MANAGER REPORT
YOUR LAB
ADDRESS, ETC
©
LTP ENDSHIFT INSTRUMENT MANAGER REPORT
YOUR LAB
ADDRESS, ETC
©
LTP OPTIMIZER/HEMATOLOGY™
WHAT LTP OPTIMIZER DOES

LTP OPTIMIZER/HEMATOLOGYTM is
software that helps you optimize specimen
results throughput in the laboratory

It uses your results-verification criteria to
measure the overall specimen-result review rate
in the laboratory
 It determines the frequency of follow-ups based
on each criterion, and the frequency of each
follow-up procedure such as analyzer reruns or
manual differentials
 It allows you to adjust the criteria and re-analyze
the results so that you can optimize your criteria
and improve throughput
©
59
LTP OPTIMIZER/HEMATOLOGY™
WHAT LTP OPTIMIZER DOES
Features
 LTP
OPTIMIZER/HEMATOLOGYTM
provides review rates:
 For all specimens combined
 Based on individual review criterion
 Based
on instrument, for multiple-instrument
systems
 Based on instrument model, for labs using
more than one analyzer model (open
architecture)
 Based on body fluid type, for labs running
whole blood samples and other body fluids
 Based on species, for veterinary labs
©
60
LTP OPTIMIZER/HEMATOLOGY™
LTP OPTIMIZER QUERY MODULE
Functions

Queries either the live or archival database for
performance parameters
Productivity summary by analyzer or by operator
 # of specimens analyzed over time interval per species,
analyzer, tech, body fluid type, etc.
 # of specimens work-listed per rule, per species, per
analyzer, per body fluid type
 # of follow-up actions per rule, per species, per analyzer,
per body fluid type

Features


©
Analysis of archived results based on rules
applied live
Analysis of archived results using modified
review rules
61
LTP OPTIMIZER QUERY CATEGORIES SCREEN
©
LTP OPTIMIZER QUERY RESULTS SCREEN
©
LTP HEMATOLOGY™
HOW LTP REDUCES OPERATING COSTS
Redeployment of skilled results-review
staff
 Eliminates erroneous specimen record
handling decisions
 Optimizes review criteria/follow-up
processes
 Provides audit trail

©
64
LTP HEMATOLOGY™
Hematology Products
LTP BAL/HEMATOLOGY™
LTP MOUSE BAL™
LTP RAT BAL™
LTP GUINEA PIG
BAL™
LTP MONKEY BAL™
LTP QC SENTINEL/HEMATOLOGY™
©
65
LTP BAL/HEMATOLOGY™
WHAT LTP BAL/HEMATOLOGY DOES

LTP BAL/HEMATOLOGY is software that
automates BAL fluid specimen analyses on
ADVIA 120/2120



No sample preparation
Reduces sample analysis time to approximately 1
minute/sample
Reports results in XL spreadsheet format
WBC
 #,%Neuts
 #,%Eos
 #,% Mononuclear cells


Does NOT affect or alter ADVIA 120/2120 software
©
66
LTP BAL/HEMATOLOGY™
WHAT LTP BAL/HEMATOLOGY DOES

Product Features





WBC count @20 cells/µL
Differential @50 cells/µL
No RBC interference in WBC analysis
Species supported
 Mouse allergic model and smoke inhalation model
 Rat allergic model and smoke inhalation model
 Cynomolgus monkey allergic model
 Guinea pig allergic model
Does NOT affect or alter ADVIA 120/2120 software
©
67
LTP
Mouse
BAL/HEMATOLOGY
™
LTP MOUSE BAL™
Whole Blood
Comparative Results
Mouse BAL
WBC
(/uL)
%N
%E
%L
%MNC
MAN
103
7.0
55.7
6.7
30.7
WB
ARCH
180
12.6
38.7
32.
8
15.9
BAL
ARCH
100
0.0
50.0
10.
0
40.0
Eos Model
Whole Blood
Archetype
Lipid
Mouse BAL
Eos Model
BAL Archetype
MN
MNC
PMN
Eos
Lymphs
©
68
LTP
Mouse
BAL/HEMATOLOGY
™
LTP MOUSE BAL™
Mouse BAL
EOS + Neuts
Model
Comparative Results
Whole Blood
Archetype
Mouse BAL
Eos + Neuts
Model
WBC
(/uL)
%N
%E
%L
%MNC
MAN
No
Manual
31
8
3
58
WB
ARCH
NA
16.2
13.8
25.2
43.9
BAL
ARCH
NA
37.8
8.9
13.3
40.0
BAL Archetype
©
69
Mouse
LTP
BAL/HEMATOLOGY
™
LTP MOUSE BAL™
Mouse BAL
Smoke Inhalation
Comparative Results
Negative Control
WBC
(/uL)
%N
%MNC
MAN
12.5
0.5
99.5
WB
ARCH
70
28.3
47.2
BAL
ARCH
20
0
100
Whole Blood
Archetype
Mouse BAL
Smoke Inhalation
Negative Control
BAL Archetype
©
70
LTP
Mouse
BAL/HEMATOLOGY
™
LTP MOUSE BAL™
Mouse BAL
Smoke Inhalation
Comparative Results
Positive CTRL
WBC
(/uL)
%N
%MNC
MAN
142.5
43.5
56.5
WB
ARCH
460
50.9
32.0
BAL
ARCH
120
50
50
Whole Blood
Archetype
Mouse BAL
Smoke Inhalation
Positive CTRL
Debris
BAL Archetype
©
71
Mouse
LTP
BAL/HEMATOLOGY
™
LTP MOUSE BAL™
Mouse BAL
Smoke Inhalation
Comparative Results
Drug-Treated
WBC
(/uL)
%N
%MNC
MAN
70
28
72
WB
ARCH
190
28.5
47.8
BAL
ARCH
58
31
69
Whole Blood
Archetype
Mouse BAL
Smoke Inhalation
Drug-Treated
BAL Archetype
©
72
LTP
Rat
BAL/HEMATOLOGY
™
Whole Blood
LTP RAT BAL™
BAL
Comparative Results
Allergic Model
WBC
(/uL)
%N
%E
%MNC
MAN
133
8
5
87
WB
ARCH
140
36.6
3.6
59.9
BAL
ARCH
130
13.8
1.5
84.6
Negative Control
Whole Blood
Archetype
BAL
Allergic Model
Negative Control
MNC
Debris
MN
PMN
Eos
BAL Archetype
©
Neuts
Lymphs
73
Rat
LTP
BAL/HEMATOLOGY
™
LTP RAT BAL™
Rat BAL
Allergic Model
Positive Control
Comparative Results
Whole Blood
Archetype
WBC
(/uL)
%N
%E
%MNC
MAN
450
34
29
37
WB
ARCH
460
40.7
26.9
30.8
BAL
ARCH
421
45.6
21.1
33.3
Rat BAL
Allergic Model
Positive Control
BAL Archetype
©
74
Rat
LTP
BAL/HEMATOLOGY
™
LTP RAT BAL™
Rat BAL
Allergic Model
Comparative Results
Drug-Treated
WBC
(/uL)
%N
%E
%MNC
MAN
623
25
65
10
WB
ARCH
620
14.3
70.0
15.5
BAL
ARCH
576
24.8
59.5
15.6
Whole Blood
Archetype
Rat BAL
Allergic Model
Drug-Treated
BAL Archetype
©
75
LTP
Cynomolgus
Monkey
BAL/HEMATOLOGY
™
Whole Blood
LTP MONKEY BAL™
Cyno Monkey BAL
Comparative Results
Allergic Model
WBC
(/uL)
%N
%E
%MNC
MAN
100
1
1
98
WB
ARCH
190
39.7
1.3
59
BAL
ARCH
92
7.5
6
86.5
Negative Control
Whole Blood
Archetype
Cyno Monkey
Allergic Model
Debris
MNC
MN
PMN
Negative Control
Eos
BAL Archetype
Lymphs
Neuts
©
76
Cynomolgus
Monkey
LTP
BAL/HEMATOLOGY
™
LTP MONKEY BAL™
Cyno Monkey BAL
Allergic Model
Positive Control
Comparative Results
Whole Blood
Archetype
Cyno Monkey BAL
Allergic Model
WBC
(/uL)
%N
%E
%MNC
MAN
346
7.3
49.0
43.7
WB
ARCH
440
52.0
12.0
36.0
BAL
ARCH
342
4.5
39.7
55.7
Positive Control
BAL Archetype
©
77
LTP
Guinea Pig
BAL/HEMATOLOGY
™
LTP GUINEA PIG
Whole Blood
BAL™
Comparative Results
Guinea Pig BAL
Allergic Model
WBC
(/uL)
%Neut
%Eos
%MNC
Man
2900
36.5
45.5
18.0
WB
Arch
2950
46.4
29.4
24.2
BAL
Arch
2950
31.0
45.5
23.5
Positive Control
Whole Blood
Archetype
Guinea Pig BAL
Allergic Model
Debris
NMC
Positive Control
BAL Archetype
©
Eos
Neuts
Debris
78
LTP BAL/HEMATOLOGY™
HOW LTP REDUCES OPERATING COSTS




Automate time intensive manual process
Provide standardized objective criteria
Reduces specimen analysis time
Allows redeployment of skilled staff
©
79
LTP COAGULATION™
Coagulation Products
LTP ACHIEVER/COAGULATION™
LTP OPTIMIZER/COAGULATION™
LTP QC SENTINEL/COAGULATION™
©
80
LTP ACHIEVER/COAGULATION™
WHAT LTP ACHIEVER DOES

LTP ACHIEVER /COAGULATION is a
complete results processing system.



Auto-verifies coagulation analyzer results
Issues follow-up worklists along with procedures
Provides data entry screens for necessary results
changes
 Determines final disposition
 Transmits results to the host computer system for
release
 Stores every state of every specimen record in a
database
©
81
LTP ACHIEVER/COAGULATION™
WHAT LTP ACHIEVER DOES
Features

Open architecture supports any combination of:
 Analyzer manufacturers/models
 Body fluid types
 Species

Analyzes specimen results on-line in real-time,
using your verification criteria.
 Special verification options include:
– Activation/de-activation of individual rules within a set
– Advanced delta-check techniques
– Rerun-only criteria
©
82
LTP ACHIEVER/COAGULATION™
WHAT LTP ACHIEVER DOES
Features


Follow-up procedure worklists are created based
on your criteria
Audit trail maintenance:
Database archival of up to 500,000 specimen records
 Every state of every record is stored in a database
 All changes made to results are recorded/audit trailed

– WHO, WHEN and WHY any change was made
– WHAT Method used to make the change

Final disposition state for each specimen record
is recorded
©
83
LTP OPTIMIZER/COAGULATION™
WHAT LTP OPTIMIZER DOES

LTP OPTIMIZER /COAGULATION ™ is
software that helps you optimize specimen
results throughput in the laboratory

It uses your coagulation results-verification
criteria to measure the overall specimen-result
review rate in the laboratory
 It determines the frequency of follow-ups based
on each criterion, and the frequency of each
follow-up procedure such as analyzer reruns or
prolonged clotting times
 It allows you to adjust the criteria and re-analyze
the results so that you can optimize your criteria
and improve throughput
©
84
LTP OPTIMIZER/COAGULATION™
WHAT LTP OPTIMIZER DOES
Features

LTP OPTIMIZER /COAGULATION ™ provides
review rates:
 For all specimens combined
 Based on individual review criterion
 Based on instrument, for multiple-instrument
systems
 Based on instrument model, for labs using
more than one analyzer model (open
architecture)
 Based on body fluid type, for labs running
whole blood samples and other body fluids
 Based on species, for veterinary labs
©
85
LTP CHEMISTRY™
Chemistry Products
LTP ACHIEVER/CHEMISTRY™
LTP OPTIMIZER/CHEMISTRY™
LTP QC SENTINEL/CHEMISTRY™
©
86
LTP ACHIEVER/CHEMISTRY™
WHAT LTP ACHIEVER DOES

LTP ACHIEVER/CHEMISTRY is a complete
results processing system.



Auto-verifies chemistry analyzer results
Issues follow-up worklists along with procedures
Provides data entry screens for necessary results
changes
 Determines final disposition
 Transmits results to the host computer system for
release
 Stores every state of every specimen record in a
database
©
87
LTP ACHIEVER/CHEMISTRY™
WHAT LTP ACHIEVER DOES
Features

Open architecture supports any combination of:
 Analyzer manufacturers/models
 Body fluid types
 Species

Analyzes specimen results on-line in real-time,
using your verification criteria.
 Special verification options include:
– Activation/de-activation of individual rules within a set
– Advanced delta-check techniques
– Rerun-only criteria
©
88
LTP ACHIEVER/CHEMISTRY™
WHAT LTP ACHIEVER DOES
Features


Follow-up procedure worklists are created based
on your criteria
Audit trail maintenance:
Database archival of up to 500,000 specimen records
 Every state of every record is stored in a database
 All changes made to results are recorded/audit trailed

– WHO, WHEN and WHY any change was made
– WHAT Method used to make the change

Final disposition state for each specimen record
is recorded
©
89
LTP OPTIMIZER/CHEMISTRY™
WHAT LTP OPTIMIZER DOES

LTP OPTIMIZER/CHEMISTRY ™ is software
that helps you optimize specimen results
throughput in the laboratory

It uses your chemistry results-verification criteria
to measure the overall specimen-result review
rate in the laboratory
 It determines the frequency of follow-ups based
on each criterion, and the frequency of each
follow-up procedure such as analyzer reruns,
below detection limit or dilutions needed.
 It allows you to adjust the criteria and re-analyze
the results so that you can optimize your criteria
and improve throughput
©
90
LTP OPTIMIZER/CHEMISTRY™
WHAT LTP OPTIMIZER DOES
Features
 LTP
OPTIMIZER /CHEMISTRY ™
provides review rates:
 For all specimens and parameters combined
 Based on your individual review criterion
 Based
on instrument, for multiple-instrument
systems
 Based on instrument model, for labs using
more than one analyzer model (open
architecture)
 Based on body fluid type, for labs running
whole blood samples and other body fluids
 Based on species, for veterinary labs
©
91
LTP URINALYSIS™
Urinalysis Products
LTP ACHIEVER/URINALYSIS™
LTP OPTIMIZER/URINALYSIS™
LTP QC SENTINEL/URINALYSIS™
©
92
LTP ACHIEVER/URINALYSIS™
WHAT LTP ACHIEVER DOES

LTP ACHIEVER/URINALYSIS is a complete
results processing system.






©
Auto-verifies urinalysis analyzer results
Issues follow-up worklists along with procedures
Provides data entry screens for necessary results
changes
 On-screen microscopic observation data entry pad
Determines final disposition
Transmits results to the host computer system for
release
Stores every state of every specimen record in a
database
93
LTP ACHIEVER/URINALYSIS™
WHAT LTP ACHIEVER DOES
Features:

Open architecture supports any combination of:
 Analyzer manufacturers/models
 Body fluid types
 Species

Analyzes specimen results on-line in real-time,
using your verification criteria.
 Special verification options include:
– Activation/de-activation of individual rules within a set
– Advanced delta-check techniques
– Rerun-only criteria
©
94
LTP ACHIEVER/URINALYSIS™
WHAT LTP ACHIEVER DOES
Features


Follow-up procedure worklists are created based
on your criteria
Audit trail maintenance:
Database archival of up to 500,000 specimen records
 Every state of every record is stored in a database
 All changes made to results are recorded/audit trailed

– WHO, WHEN and WHY any change was made
– WHAT Method used to make the change

Final disposition state for each specimen record
is recorded
©
95
LTP OPTIMIZER/URINALYSIS™
WHAT LTP OPTIMIZER DOES

LTP OPTIMIZER/URINALYSIS™ is software
that helps you optimize specimen results
throughput in the laboratory

It uses your urinalysis results-verification criteria
to measure the overall specimen-result review
rate in the laboratory
 It determines the frequency of follow-ups based
on each criterion, and the frequency of each
follow-up procedure such as analyzer reruns or
microscopic element types (eg. crystals)
 It allows you to adjust the criteria and re-analyze
the results so that you can optimize your criteria
and improve throughput
©
96
LTP OPTIMIZER/URINALYSIS™
WHAT LTP OPTIMIZER DOES

Features
 provides review rates:
 For all specimens combined
 Based on your individual review criterion
 Based on instrument, for multiple-instrument
systems
 Based on instrument model, for labs using
more than one analyzer model (open
architecture)
 Based on body fluid type, for labs running
whole blood samples and other body fluids
 Based on species, for veterinary labs
©
97
LabThroughPut
™
Products
Quality Control Module
LTP QC SENTINEL™
LTP
HEMATOLOGY™
LTP
COAGULATION™
LTP CHEMISTRY™
LTP URINALYSIS™
QC SENTINEL MODULE
IS PRESENTLY UNDER
DEVELOPMENT
©
98
General LIS Configuration
WITHOUT LTP MIDDLEWARE
 An
LIS has multiple connections and
interfaces, in multiple categories
 Analyzer
– LIS
A
different interface for each analyzer
brand
 Numerous
Data Entry Workstations
 Printers
©
99
General LIS Configuration
SLIDES
SLIDES
SLIDES
SLIDES
DIFFS
SLIDES
BC PRT
DIFFS
DIFFS
DIFFS
DIFFS
DIFFS
DIFFS
DIFFS
A1
A2
A3
PRT
DIFFS = Diff-reader workstations
A4
A5
1-6
8-15
Sup
WS1
A6
Sup
WS2
ANTRIM
Sup
WS3
3. Analyzer-to-ANTRIM failsafe direct serial port
connections not shown.
A14
Main
Server
CD2
CD4
Notes:
2. InstMgr-to-Analyzer and InstMgr-to-ANTRIM
connections via serial ports.
A13
©
A1-A14 = ADVIA 120 Analyzers
1. Server-to-Server connection by dedicated
NICs.
A12
CD3
External Storage = Terabyte drive
CD1-CD4 = CellDyn 3500 Analyzers
A11
CD1
BC PRT = Barcode printer
InstMgr12 = Instrument Manager workstation
A8
A10
PRT = Printer
SUP WS1-3 = Supervisor workstations
A7
A9
SLIDES = slide-making workstations
External
Storage
Backup
Server
4. Circled numbers are hub connection #s
LTP MIDDLEWARE™ SYSTEM Configuration
WITH LTP MIDDLEWARE
The LIS has only a single connection to LTP
Middleware
 LTP Middleware is responsible for interfacing to
the various categories of devices
 LTP Middleware unburdens the LIS of
interfacing with multiple laboratory devices,
each with its own interface specification
 Bidirectional LTP Middleware – LIS
interfaces follow standards such as
ASTM1381/1395 or HL7

©
101
LTP Middleware System Configuration
SLIDES
SLIDES
SLIDES
SLIDES
DIFFS
SLIDES
BC PRT
DIFFS
DIFFS
DIFFS
DIFFS
DIFFS
DIFFS
DIFFS
A1
1-6
A2
DSL
7
A3
8-15
PRT
DIFFS = Diff-reader workstations
A4
Hub
A5
16-19
A8
A9
21
22
LTP
Inst
Mgr
PRT = Printer
BC PRT = Barcode printer
SUP WS1-3 = Supervisor workstations
InstMgr12 = Instrument Manager workstation
Sup
WS2
Main
Server
A10
Backup
Server
External
Storage
A13
External Storage = Terabyte drive
A1-A14 = ADVIA 120 Analyzers
CD1-CD4 = CellDyn 3500 Analyzers
Sup
WS3
A11
A12
Sup
WS1
20
A6
A7
SLIDES = slide-making workstations
Notes:
1. Server-to-Server connection by dedicated
NICs.
2. InstMgr-to-Analyzer and InstMgr-to-ANTRIM
connections via serial ports.
3. Analyzer-to-ANTRIM failsafe direct serial port
connections not shown.
A14
4. Circled numbers are hub connection #s
CD1
CD2
CD3
©
CD4
ANTRIM
LTP MIDDLEWARE™ SYSTEM
LTP System Backup

LTP MIDDLEWARE automatically copies
the system environment, including
applications and DB, to External Media daily
 LTP MIDDLEWARE also continually
replicates the environment to a Backup
Server
 The LTP Backup Server automatically
takes over if the Main Server fails
©
103
LTP MIDDLEWARE™ SYSTEM
LTP System Technical Support
LTP TECHNICAL SUPPORT

Available whenever the laboratory is in
operation
 Lab personnel can call a telephone number
and speak directly with support staff
 Support staff have remote access to the
middleware system which enables them to
quickly diagnose a problem and to make any
necessary changes
©
104
Thank You
for your attention.
www.labthroughput.com
845-425-9711
845-270-8449
©
105