Curriculum Vitae
PERSONAL INFORMATION
Paolo Paolucci
WORK EXPERIENCE
January 1985–February 1993
Co-ordinator
University of Bologna, (Italy)
Bone Marrow Transplantation Unit at the Paediatric Clinic
March 1993–March 1996
Director
Azienda Sanitaria Locale , (Italy)
Unit of Paediatrics at the Hospital of Lugo (RA)
April 1996–October 2002
Director
IRCCS-Hospital San Giovanni Rotondo (FG), (Italy)
Unit of Paediatrics
November 2002–Present
Director
University of Modena and Reggio Emilia, (Italy)
Unit of Paediatric Hematology, Oncology and Bone Marrow Transplantation
January 2004–Present
Director
University of Modena and Reggio Emilia, (Italy)
Department of Mother and Child
November 2009–Present
Director
University of Modena and Reggio Emilia, (Italy)
Unit of Paediatrics
November 1979–October 1985
Co-ordinator
University of Bologna, (Italy)
Laboratory of Paediatric Immunology
November 1985–February 1993
Co-ordinator
University of Bologna, (Italy)
Laboratory of cytogenetics and cell biology
September 1986–September
1988
Founder and Chairman
Italian Association of Paediatric Hematology and Oncology, (Italy)
Italian Study Group for Bone Marrow Transplantation
September 1986–September
1995
Founder and Chairman
Italian Association of Paediatric Hematology and Oncology, (Italy)
Italian Registry of Paediatric Bone Marrow Transplantation
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Curriculum Vitae
September 1996–September
2006
Paolo Paolucci
Founder and Member
European Blood and Bone Marrow Transplantation Group (EBMT) , (Italy)
Working Party “Paediatric Diseases”
August 2008–Present
Alternate Member
European Medicines Agency, (United Kingdom)
Health Professional at the Paediatric Committee (PDCO)
January 2013–December 2014
Member
Ministery of Education, Research and University, (Italy)
National Committee for Professorship Evaluation and Assignement
in Paediatrics
EDUCATION AND TRAINING
November 1966–October 1972
Medical Doctor Degree
School of Medicine - University of Bologna, (Italy)
Graduation with 110 / 110 cum laude
November 1972–October 1975
Specialist in Paediatrics
Post-graduate School of Paediatrics- University of Bologna, (Italy)
Graduation with 70 / 70 cum laude
November 1975–October 1976
Specialist in theory and application of calculators
Post-graduate School of Mathematics - University of Bologna, (Italy)
Graduation with 28 / 30
November 1976–October 1978
Specialist in Neonatology
Post-graduate School of Neonatology - University of Bologna, (Italy)
Graduation with 70 / 70 cum laude
November 1980–October 1983
Specialist in Allergology and Clinical Immunology
Post-graduate School of Allergology and Clinical Immunology - University of Florence, (Italy)
Graduation with 70 / 70 cum laude
February 1978–December 1979
Research Fellow
Hospital for Sick Children/Institute of Child Health, (United Kingdom)
Research and clinical training in paediatric hematology, immunology and allergology
December 1984–December 1985
Research Fellow
St. Jude Children's Research Hospital, (United States)
Clinical and research training in paediatric bone marrow transplantation
ADDITIONAL INFORMATION
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Curriculum Vitae
Expertise
Paolo Paolucci
Scientific interests
• Cellular and molecular bases of congenital defects of immunity
• Paediatric Haematology and Oncology
• Haemopoietic Stem Cells Transplantation
• Gene expression profile in paediatrics (pharmacogenomics)
• Cell therapies in paediatric oncology
• Development of Clinical Trials in Paediatrics
• Role and applications of mesenchimal stem cells in regenerative medicine
Publications
A list of the most significant publications over the last 14 years (2000 - 2014) follows:
1. Haemopoietic stem cell transplantation in childhood: report from the bone marrow transplantation
group of the associazione italiana di ematologia e oncologia pediatrica (AIEOP). A. .Pession, R.
Rondelli, Paolucci P, G. Pastore, G. Dini, F. Bonetti, E. Madon, F. Mandelli, L. Zanesco, C. Uderzo, A.
Prete, M. Rabusin, A. Ugazio, P. Di Bartolomeo, C. Favre, L.B. Faulkner, V. Poggi, R. Luksch, A.
Donfrancesco, F. Argiolu, G. La Nasa, A. Amici, F. Locatelli.
Haematologica 2000; 85: 638-646.
2. Expansion of hemathogones in a patient with Gaucher disease. G. D’Arena, M. Bisceglia, S.
Ladogana, A.M. Carella, M. Carotenuto, Paolucci P.
Med. Ped. Oncol. 2001; 34: 1-2.
3. A dysfunctional factor X (factor X San Giovanni Rotondo) present at homozygous and double
heterozygous level: identification of a novel microdeletion (delc556) and missense mutation
(lys(408)---asn) in the factor x gene. a study of an italian family. P. Simioni, F. Vianello, M. Kalafatis, L.
Barzon, S. Ladogana, Paolucci P, M. Carotenuto, F. Dal Bello, G. Palu, A. Girolami.
Thromb. Res. 2001; 101 (4): 219-230.
4. Microchips and clinical practice. P. Gasparini, Paolucci P.
Ital. J. Pediatr. 2003; 29: 12-17.
5. Neuroblastic tumors associated with opsoclonus-myoclonus syndrome: histological,
immunohistochemical and molecular features of 15 italian cases. C. Gambini, M. Conte, G. Bernini,
P.Angelici, A. Pession, Paolucci P, A. Donfrancesco, E. Veneselli, K. Mazzocco, GP Tonini, L.
Raffaghello, C. Dominaci, A. Morando, F. Negri, C. Favre, B. De Bernardi, V. Pistoia.
Virchows Arch. 2003; 442: 555-562.
6. La leucemia linfoblastica acuta: un modello di percorso terapeutico della pediatria moderna. V.
Conter, M. Jankovic, C. Rizzari, G. Palazzi, A. Sala, Paolucci P.
Prospettive in Pediatria 2004; 136 (34): 261-270.
7. The development in the understanding of pain in children. N. Sturloni, E. Garetti, Paolucci P.
The Suffering Child 2004; 4: 48-52.
8. Variazioni temporali dei flussi migratori per trapianto di cellule staminali emopoietiche (TCSE) tra
centri aderenti all’associazione italiana di ematologia e oncologia pediatrica. R. Rondelli, L. Gualandi,
F. locatelli, F. Ronchetti, G. Dini, M. Zecca, F. Fagioli, S. Cesaro, A. Prete, C. Uderzo, R. Luksch, F.
Porta, A. Donfrancesco, G. Meloni, C. Favre, L. Faulkner, M. Andolina, M. Rifaldi, P. Zucchetti, A. Di
Cataldo, P. Pierani, S. Ladogana, F.Argiolu, G. De Rossi, P. Di Bartolomeo, P. Marradi, Paolucci P, G.
La Nasa; C. Messina, A. Pession. XXXI Congresso Nazionale Associazione Italiana Ematologia
Oncologia Pediatrica, Stresa, 10-12 ottobre 2004.
Haematologica 2004; 89 (suppl. n. 10): 134.
9. Linea guida AIEOP sulla porpora trombocitopenica immune acuta: grado di implementazione 19992002. D. De Mattia, GC. Del Vecchio, A. De Santis, P. Giordano, G. Amendola, A. Arrighini, C. Baronci,
D. Del Principe, R. De Santis, AC. Molinari, M. Jankovic, S. Magro, L. Nespoli, B. Nobili, M. Nardi,
Paolucci P, G. Paone, U. Ramenghi, G. Russo, V. Sabato, F. Tucci, M. Zecca.
Haematologica 2004; 89 (suppl. n. 10): 156.
10. Rituximab induces different but overlapping sets of genes in human B lymphoma cell lines. E.
Cittera, C. Onofri, M. D’Apolito, G. Cartron, G. Cazzaniga, L. Zelante, Paolucci P, A. Biondi, M. Introna,
J. Golay.
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Paolo Paolucci
Cancer Immunol. Immunother. 2005; 54, 273-286.
11. Efficacy and safety of recombinant urate oxidase (rasburicase) for treatment and prophylaxis of
hyperuricemia in children undergoin chemiotherapy. A. Pession, E. Barbieri, N. Santoro, Paolucci P, F.
Porta, F. Locatelli.
Paediatric Haematol. Oncol. 2005; 90: 141-142.
12. Persistently high IgA serum levels are a marker of immunologic or virologic failure of combined
antiretroviral therapy in children with perinatal HIV-1 infection. E. Chiappini, L.Galli, M. Cellini, MC
Cano, Paolucci P et al for The Italian Register for HIV Infection in Children
Clin. Exp. Immunol. 2005; 140: 320-324.
13. Phase II study of a protracted irinotecan schedule in children with refractory or recurrent soft tissue
sarcoma. G. Bisogno, R.
Riccardi, A. Ruggiero, G. Arcamone, A. Prete, G. Surico, M. Provenzi, P. Bertolini, Paolucci P, Carli M.
Cancer 2006; 106 (3): 703-707.
14. Plasma levels of receptor activator of nuclear factor-kappab ligand and osteoprotegerin in patients
with neuroblastoma. D. Granchi, A. Garaventa, I. Amato, Paolucci P, Baldini N.
Int. J. Cancer 2006; 119 (1): 146-51.
15. G1 cell-cycle arrest and apoptosis by histone deacetylase inhibition in MLL-AF9 acute myeloid
leukemia cells is p21 dependent and MLL-AF9 independent. R. Tonelli, R. Sartini, R. Fronza, F.
Freccero, M. Franzoni, D. Dongiovanni, M. Ballarini, S. Ferrari, M. D'apolito, G. Di Cola, G. Capranico,
A. Khobta, R. Campanini, Paolucci P, S. Minucci, A. Pession.
Leukemia 2006; 20 (7): 1307-10.
16. Two consecutive immunophenotypic switches in a child with MLL-rearranged acute lymphoblastic
leukemia. G. Germano, M. Pigazzi, L. Del Giudice, M. Campo Dell’Orto, M. Spinelli, A. Zangrando
Paolucci P, S. Ladogana, G.Basso.
Haematologica 2006; 91 (5): 217-9.
17. Assessment of submicroscopic genetic lesions by single nucleotide polymorphism array in a child
with acute myeloid leukemia and FLT3-internal tandem duplication. S. Bungaro, M. Raghavan, M.G.
Dell’Oro, Paolucci P, B.D. Young, A. Biondi, G. Cazzaniga.
Haematologica 2006; 91 (7): 998-1000.
18. Identification of a molecular signature predictive of sensitivity to differentiation induction in acute
myeloid leukemia. E. Tagliafico, E. Tenedini, R. Manfredini, A. Grande, F. Ferrari, E. Roncaglia, S.
Bicciato, R. Zini, S. Salati, E. Bianchi, C. Gemelli, M. Montanari, T. Vignudelli, T. Zanocco-Marani, S.
Parenti, Paolucci P, G. Martinelli, P.P. Piccaluga, M. Baccarani, G. Specchia, U. Torelli, S. Ferrari.
Leukemia 2006; 20 (10): 1751-8.
19. Chromosomal locus 19p13 as potential hotspot for aberrant gene expression in relapsed
paediatric acute lymphoblastic leukemia. M. Lanciotti, M. D’Apolito, Paolucci P, C. Dufour.
Br. J. Haematol. 2006; 135 (2): 274-5.
20. Virologic, immunologic and clinical benefits from early combined antiretroviral therapy in infants
with perinatal HIV-1 infection. E. Chiappini, L.Galli, M. Cellini, M.C. Cano, Paolucci P et al for The
Italian Register for HIV Infection in Children
AIDS 2006; 25: 97-101.
21. Cancer rates after year 2000 significantly decrease in children with perinatal HIV infection: a study
by the Italian Register for HIV Infection in Children. E. Chiappini, L.Galli, M. Cellini, M.C. Cano,
Paolucci P et al for The Italian Register for HIV Infection in Children
J. Clin. Oncol. 2007; 25: 97-101.
22. Challanges in drug prescribing for children with cancer. Paolucci P, K. Pritchard Jones, M.C. Cano
Garcinuno, M. Catapano, A. Iolascon, A.Ceci.
Lancet Oncol. 2008; 9: 176-183.
23. Donor cell-derived osteopoiesis originates from a self-renewing stem cell with a limited
regenerative contribution after transplantation. M. Dominici, R. Marino, V. Rasini, C. Spano, Paolucci
P, PF. Conte, T.J. Hofmann, E.M. Horwitz.
Blood 2008; 111: 4386-91.
24. Assessment of aspergillus-specific T cells for diagnosis of invasive aspergillosis in a leukemic child
with liver lesions mimicking hepatosplenic candidiasis. Potenza L, Barozzi P, Rossi G, Palazzi G,
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Vallerini D, Riva G, Cellini M, Morselli M, Volzone F, Venturelli C, Quadrelli C, Di Pancrazio L, Cano
MC, Paolucci P, Torelli G, Luppi M.
Clin Vaccine Immunol. 2008; 15(10): 1625-28.
25. Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after
marrow radioablation. Dominici
M, Rasini V, Bussolari R, Chen X, Hofmann TJ, Spano C, Bernabei D, Veronesi E, Bertoni F, Paolucci
P, Conte P, Horwitz EM.
Blood. 2009 Sep 10;114(11):2333-43.
26. Heterogeneity of Multipotent Mesenchymal Stromal Cells: From Stromal Cells to Stem Cells and
Vice Versa. Dominici M, Paolucci P, Conte PF, Horwitz EM.
Transplantation. 2009; 87: 36-42.
27. GMP-Manufactured Density Gradient Media for Optimized Mesenchymal Stromal/Stem Cells
Isolation and Expansion. Grisendi G, Annerén C, Cafarelli L, Sternieri R, Veronesi E, Cervo GL,
Luminari S, Maur M, Frassoldati A, Palazzi G, Otsuru S, Paolucci P, Conte PF, Horwitz EM, Dominici
M.
Cytotherapy. 2010 Jul;12(4):466-77.
28. Risk of hematological malignancies associated with magnetic fields exposure from power lines: a
case-control study in two municipalities of northern Italy. Carlotta Malagoli, Sara Fabbi, Sergio Teggi,
Mariagiulia Calzari, Maurizio Poli, Elena Ballotti, Barbara Notari, Maurizio Bruni, Giovanni Palazzi,
Paolucci P, Marco Vinceti.
Environ Health. 2010 Mar 30;9:16.
29. Adipose-Derived Mesenchymal Stem Cells as Stable Source of Tumor Necrosis Factor-Related
Apoptosis-Inducing Ligand Delivery for Cancer Therapy. Grisendi G, Bussolari R, Cafarelli L, Petak I,
Rasini V, Veronesi E, De Santis G, Spano C, Tagliazzucchi M, Barti-Juhasz H, Scarabelli L, Bambi F,
Frassoldati A, Rossi G, Casali C, Morandi U, Horwitz EM, Paolucci P, Conte P, Dominici M.
Cancer Res. 2010 May 1;70(9):3718-29.
30. The European paediatric legislation: benefits and perspectives. Rocchi F, Paolucci P, Ceci A, Rossi
P.
Ital J Pediatr. 2010 Aug 17;36:56.
31. Needs and PIPs by therapeutic classes: oncology. Paolucci P, Cioni V, Caramaschi E, Cano C.
Pharmaceut Policy and Law 2010; 12 (1-2): 109-113.
32. Gene expression profiling: a possible tool in the prediction of outcome in paediatric acute
lymphoblastic leukaemia?
Lanciotti M, D'Apolito M, Paolucci P, Indaco S, Dufour C.
Br J Haematol. 2011 Apr;153(2):279-82.
33. Neuroblastoma and bone metastases: clinical significance and prognostic value of Dickkopf 1
plasma levels.
Granchi D, Corrias MV, Garaventa A, Baglìo SR, Cangemi G, Carlini B, Paolucci, Giunti A, Baldini N.
Bone. 2011 Jan; 48(1): 152-9.
34. Pediatric pharmacogenetic and pharmacogenomic studies: the current state and future
perspectives. Russo R, Capasso M, Paolucci P, Iolascon A..
Eur J Clin Pharmacol. 2011 May;67 Suppl:17-27.
35. Endpoints in Paediatric Oncology.
Paolucci P, Cioni V, Bigi E, Lucaccioni L, Cano C.
Eur J Clin Pharmacol 2011; 67 Suppl 1: 33-40.
36. Understanding tumor-stroma interplays for targeted therapies by armed mesenchymal stromal
progenitors: the Mesenkillers.
Grisendi G, Bussolari R, Veronesi E, Piccinno S, Burns JS, De Santis G, Loschi P, Pignatti M, Di
Benedetto F, Ballarin R, Di Gregorio C, Guarneri V, Piccinini L, Horwitz EM, Paolucci P, Conte P,
Dominici M.
Am J Cancer Res. 2011;1(6):787-805.
37. Non-invasive methods can predict oesophageal varices in patients with biliary atresia after a Kasai
procedure.
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Colecchia A, Di Biase AR, Scaioli E, Predieri B, Iughetti L, Reggiani ML, Montrone L, Ceccarelli PL,
Vestito A, Viola L, Paolucci P, Festi D.
Dig Liver Dis. 2011 Aug;43(8):659-63.
38. An adoptive immuno-gene therapy approach targeting neuroblastoma.
Caldrer S, Spano C, Grisendi g, Ceccarelli GB, Bestagno M, Campana D, Conte PF, Dominici M,
Paolucci P.
Pediatric Blood & Cancer. 2011; 57 (5): 783-784.
39. Obesity in patients with acute lymphoblastic leukemia in childhood.
Iughetti L, Bruzzi P, Predieri B, Paolucci P.
Ital J Pediatr. 2012 Jan 27;38:41-43.
40. Epidemiology of infections in children with acquired aplastic anaemia: a retrospective multicenter
study in Italy.
Quarello P, Saracco P, Giacchino M, Caselli D, Caviglia I, Longoni D, Varotto S, Rana I, Amendola A,
Misuraca A, Licciardello M, Paolucci P, Ladogana S, Rivetti E, Dufour C, Castagnola E.
Eur J Haematol. 2012; 88 (6): 526-534.
41. Unusual osseous presentation of blastomycosis in an immigrant child: A challenge for European
pediatricians.
Codifava M, Guerra A, Rossi G, Paolucci P, Iughetti L.
Ital J Pediatr 2012; 38 (1): 69-71.
42. Incidental diagnosis of thoracic ganglioneuroblastoma in a 3-year-old female with wheezing.
Lucaccioni L, Bigi E, Garcinuno CC, Paolucci P, Iughetti L.
Acta Biomed. 2012 Apr;83(1):53-5.
43. Leukemia risk in children exposed to benzene and PM10 from vehicular traffic: a case-control
study in an Italian population.
Vinceti M, Rothman KJ, Crespi CM, Sterni A, Cherubini A, Guerra L, Maffeis G, Ferretti E, Fabbi S,
Teggi S, Consonni D, De Girolamo G, Meggiato A, Palazzi G, Paolucci P, Malagoli C.
Eur J Epidemiol. 2012 Oct;27(10):781-90.
44. MSC and Tumors: Homing, Differentiation, and Secretion Influence Therapeutic Potential.
D'souza N, Burns JS, Grisendi G, Candini O, Veronesi E, Piccinno S, Horwitz EM, Paolucci P, Conte
P, Dominici M.
Adv Biochem Eng Biotechnol. 2013; 130:209-16.
45. Italian cancer figures, report 2012: Cancer in children and adolescents.
AIRTUM Working Group; CCM; AIEOP Working Group (Member).
Epidemiol Prev. 2013 Jan-Feb;37(1 Suppl 1):1-225.
46. Intellectual function evaluation of first generation immigrant children with sickle cell disease: The
role of language and sociodemographic factors.
Montanaro M, Colombatti R, Pugliese M, Migliozzi C, Zani F, Guerzoni ME, Manoli S, Manara R,
Meneghetti G, Rampazzo P, Cavalleri F, Giordan M, Paolucci P, Basso G, Palazzi G, Sainati L.
Ital J Pediatr 2013 Jun; 4: 39-46.
47. Isolation, characterization, and transduction of endometrial decidual tissue multipotent
mesenchymal stromal/stem cells from menstrual blood.
Rossignoli F, Caselli A, Grisendi G, Piccinno S, Burns JS, Murgia A, Veronesi E, Loschi P, Masini C,
Conte P, Paolucci P, Horwiz EM, Dominici M.
Biomed Res Int. 2013; 90: 18-21.
48. Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment
after radioablative conditioning.
Olson TS, Caselli A, Otsuru S, Hofmann TJ, Williams R, Paolucci P, Dominici M, Horwitz EM.
Blood. 2013 Jun 27;121(26):5238-49.
49. IGF-1-Mediated Osteoblastic Niche Expansion Enhances Long-Term Hematopoietic Stem Cell
Engraftment after Murine Bone Marrow Transplantation.
Caselli A, Olson TS, Otsuru S, Chen X, Hofmann TJ, Nah HD, Grisendi G, Paolucci P, Dominici M,
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Horwitz EM.
Stem Cells. 2013 Oct; 31(10): 2193-204.
50. Adipose stromal/stem cells assist fat transplantation reducing necrosis and increasing graft
performance.
Piccinno MS, Veronesi E, Loschi P, Pignatti M, Murgia A, Grisendi G, Castelli I, Bernabei D, Candini O,
Conte P, Paolucci P, Horwitz EM, De Santis G, Iughetti L, Dominici M.
Apoptosis. 2013 Oct;18(10):1274-89.
51. Transportation Conditions for Prompt Use of Ex Vivo Expanded and Freshly Harvested ClinicalGrade Bone Marrow Mesenchymal Stromal/Stem Cells for Bone Regeneration.
Veronesi E, Murgia A, Caselli A, Grisendi G, Piccinno MS, Rasini V, Giordano R, Montemurro T,
Bourin P, Sensebé L, Rojewski MT, Schrezenmeier H, Layrolle P, Ginebra MP, Panaitescu CB,
Gómez-Barrena E, Catani F, Paolucci P, Burns JS, Dominici M.
Tissue Eng Part C Methods 2013; 20(3):239-51.
52. Delayed Marrow Infusion in Mice Enhances Hematopoietic and Osteopoietic Engraftment by
Facilitating Transient Expansion of the Osteoblastic Niche.
Marino R, Otsuru S, Hofmann TJ, Olson TS, Rasini V, Veronesi E, Boyd K, Gaber MW, Martinez C,
Paolucci P, Dominici M, Horwitz EM.
Biol Blood Marrow Transplant 2013 Nov; 19(11): 1566-73.
53. Dancing eye syndrome as first symptom of neuroblastoma. Venturelli C, Guerra A, Paolucci P,
Iughetti L. Acta Biomed. 2013 Sep 1; 84(2):162-6.
54. Intellectual function evaluation of first generation immigrant children with sickle cell disease: the
role of language and sociodemographic factors.
Montanaro M, Colombatti R, Pugliese M, Migliozzi C, Zani F, Guerzoni ME, Manoli S, Manara R,
Meneghetti G, Rampazzo P, Cavalleri F, Giordan M, Paolucci P, Basso G, Palazzi G, Sainati L.
Ital J Pediatr. 2013 Jun 4;39:36.
55. Mesenchymal Progenitors Expressing TRAIL Induce Apoptosis in Sarcomas. Giulia Grisendi,
Carlotta Spano, Naomi D'souza, Valeria Rasini, Elena Veronesi, Malvina Prapa, Tiziana Petrachi,
Serena Piccinno, Filippo Rossignoli, Jorge S. Burns, Stefania Fiorcari, Donatella Granchi, Nicola
Baldini, Edwin M. Horwitz, Valentina Guarneri, Pierfranco Conte, Paolo Paolucci, Massimo Dominici.
Stem Cells. 2014 Nov 25. doi: 10.1002/stem.1903. [Epub ahead of print]
56. Mesenchymal progenitors aging highlights a miR-196 switch targeting HOXB7 as master regulator
of proliferation and osteogenesis. Olivia Candini, Carlotta Spano, Alba Murgia, Giulia Grisendi, Elena
Veronesi, Maria SerenaPiccinno, Manuela Ferracin, Massimo Negrini, Francesca Giacobbi, Franco
Bambi, Edwin MarkHorwitz, Pierfranco Conte, Paolo Paolucci, Massimo Dominici.
Stem Cells. 2014 Nov 26. doi: 10.1002/stem.1897. [Epub ahead of print]
57. Final height and body mass index in adult survivors of childhood acute lymphoblastic leukemia
treated without cranial radiotherapy: a retrospective longitudinal multicenter Italian study. Patrizia
Bruzzi, Barbara Predieri, Andrea Corrias, Alberto Marsciani, Maria Elisabeth Street, Aurora
Rossidivita, Paolo Paolucci, Lorenzo Iughetti.
BMC Pediatrics 09/2014; 14(1):236.
58. cGMP-Compliant Transportation Conditions for a Prompt Therapeutic Use of Marrow
Mesenchymal Stromal/Stem Cells. Elena Veronesi, Jorge Sans Burns, Alba Murgia, Olivia Candini,
Valeria Rasini, Ilenia Mastrolia, Fabio Catani, Paolo Paolucci, Massimo Dominici.
Methods Mol Biol. 2014 Aug 10. [Epub ahead of print]
59. Predictive diagnostic value for the clinical features accompanying intellectual disability in children
with pathogenic copy number variations: a multivariate analysis. Elisa Caramaschi, Ilaria Stanghellini,
Pamela Magini, Maria Grazia Giuffrida, Silvia Scullin, Tiziana Giuva, Patrizia Bergonzini, Azzurra
Guerra, Paolo Paolucci, Antonio Percesepe.
It. J. Pediatr.2014; 40(1):39-42.
60. Correlating ex vivo and in vivo osteogenic assays for quality control of clinically destined cGMP
grade BM-MSC. A. Murgia, E. Veronesi, V. Rasini, O. Candini, L. Sensebè, P. Layrolle, H.
Schrezenmeier, P. Paolucci, J. Burns, M. Dominici. Cytotherapy 04/2014; 15(4):S18–S19.
61. Modified adipose mesenchymal progenitors target Ewing's sarcoma. G. Grisendi, C. Spano, N.
D'Souza, V. Rasini, E. Veronesi, S. Piccinno, G. De Santis, E. Horwitz, P. Conte, P. Paolucci, M.
Dominici. Cytotherapy 04/2014; 16(4):S32.
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62. Sickle cell disease in areas of immigration of high-risk populations: a low cost and reproducible
method of screening in northern Italy. Donatella Venturelli, Mariachiara Lodi, Giovanni Palazzi,
Giuliano Bergonzini, Giada Doretto, Annalisa Zini, Cellini Monica, M Carmen Cano, Mariotti Ilaria,
Giuliano Montagnani, Paolo Paolucci.
Blood Transfus. 2014 Jul;12(3):346-51.
63. Paraplegia by spinal cord compression as the initial manifestation of Hodgkin's disease: a case
report. Lorenza Baroni, Sara Fornaciari, Barbara Predieri, Patrizia Bergonzini, Azzurra Guerra, Paolo
Paolucci, Lorenzo Iughetti.
Acta bio-medica: Atenei Parmensis 01/2014; 85(2):171-4.
Projects
Research projects
• Chairman, TEG in Oncology - FP6 “TEDDY (Task Force in Europe
for Drug Development for the Young) project” 2005-2010
• EU Commission appointment as “Health Professional”, Paediatric
Committee (PDCO), European Medicines Agency (EMA),
London (UK) 2008- onwards
• Chairman, Therapeutic Expert Group in Oncology - FP6 “TEDDY
(Task Force in EU for Drug Development for the Young) project”2005-2010
• EU Commission appointment as “Health Professional”, Paediatric
Committee (PDCO), European Medicines Agency (EMA),
London (UK) 2008- onwards
• Integrated follow up program for monitoring late effects of chemotherapy
in paediatric oncology: controlled, multicentre study (PI, Regione Emilia
Romagna Research Projects – Area 2 “Clinical Governance”); 2007-2010
• Gene therapy with mesenchimal stem cells carrying Tumor Necrosis Factor-Related ApoptosisInducing Ligand (TRAIL): an innovative platform for adult and children cancer therapy (PI Research
Unit - PRIN); 2008-2010
• Exploring innovative strategies to enhance bone regeneration based
on novel mesenchymal stromal stem cells (National Health Institute); 2010-2012
• Third Party, Project “Global Research In Paediatrics” (GRIP), Framework
Projects, European Commission. 2010-2015
Memberships
Memberships
1. SIP (Italian Society of Paediatrics);
2. SIPPS (Italian Society of Social and Preventive Paediatrics);
3. AIEOP (Italian Society of Paediatric Hematology and Oncology);
4. EBMT (European Blood and Bone Marrow Transplantation Group);
5. GITMO (Italian Group for Bone Marrow Transplantation);
6. SIOP (International Society of Paediatric Oncology);
7. ISCT (International Society of Cell Therapy);
8. Alternate Member as Health Professional at the Paediatric Committee (PDCO) of European
Medicines Agency (EMA);
9. Member of the National Committee for Professorship Evaluation
in Paediatrics in Italy;
Referee of International Journals
1. Medical and Pediatric Oncology (nowPediatric Blood and Cancer);
2. Italian Journal of Pediatrics;
3. Medico & Bambino;
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Curriculum Vitae
Paolo Paolucci
4. The Lancet Oncology.
Fellowships
1. Leukemia Research Fund, UK (1978-1979);
2. Leon Journey Fellowship, USA (1984);
3. Travel Fellowship, Fullbright Program (1984).
Invited speaker and chairman at national and international scientific conferences (more than 350
scientific contributions of which more than 150 at international meetings).
Other Relevant Information
- Full Professor of Paediatrics 2002-onwards
- Faculty, Post-graduate Schools (Paediatrics, Haematology,Paediatric Neuro-Psychiatry, Community
Medicine) 2002- onwards
- Director, II level Master in “Paediatric Haematology and Oncology” 2003-2005
- Director, Post-graduate School of Paediatrics 2003-2008
- Faculty, Doctorate in Rigenerative and Molecular Medicine 2004- onwards
- Representative of the University in the Administrative Council
of the Spin-Off Università-Rigenerand srl 2010- onwards
- Industrial Co-Inventor of “Method for specific cell isolation”, Patent n. MO2010A000111, (registered
14.04.2010). No clinical application.
- Industrial Co-Inventor of “Method for engineering effector cells to kill tumour cells expressing
disialoganglioside GD2”, Patent n. MO2011000270, (registered 20.05.2011). No clinical application.
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