CONCEPT OF HEALTH AND DISEASE-2 By Col Naseer Alam Tariq (Retd) HEALTH CONCEPT OF DISEASE Disease Webster defines disease – A state in which body health is impaired, a departure from a state of health, an alteration of the human body interrupting the performance of vital functions. – Oxford defines disease A condition of the body or some part or organ of the body in which its functions are disrupted or deranged Disease • Ecological point of view disease is defined A maladjustment of the human organism to the environment • The simplest definition of disease is – Disease is just the opposite of health – Any deviation from normal functioning or state of complete physical or mental well being WHO • WHO has defined health but not disease • Disease literally means “Without ease” (Uneasiness) • Disease is opposite of ease Concept of Causation of disease • Various concepts of disease causation – Supernatural theory of disease – The theory of humors – The concept of contagion – Miasmatic theory of disease – The theory of spontaneous generation – Germ theory of disease NATURAL HISTORY OF DISEASE It is the way in which a disease evolves over time from the earliest stage of its pre-pathogenesis phase to its termination as recovery, disability or death, in the absence of treatment or prevention PRE-PATHOGENESIS PHASE • Period preliminary to the onset of disease in man • The diseases agent has not yet entered the man. • The factors which favour its interaction with the human host are already existing in the environment. PATHOGENESIS PHASE • The pathogenesis phase begins with the entry of the disease agent in the susceptible human host. Natural History of Disease Disease results from a complex interaction between man, agent and the environment EPIDEMIOLOGICAL TRIAD ENVIRONMENT AGENT HOST Agent • The disease agent is A substance , living or non living, or a force, tangible or intangible, the excessive presence or relative lack of which may initiate or perpetuate a disease process. • Disease may have a single or a number of independent agents or a Agent • Biological agents- living agent of disease Bacteria, Viruses, protozoa, fungi, rickettsia • Nutrient agents- Protein, carbohydrate, vitamins, minerals and water Any excess or deficiency of the nutrient elements may result in nutritional disorders, anemia, goiter, obesity • Physical agents –Exposure to excessive heat, cold, humidity, pressure, radiation, sound Agents • Chemical agents- metal fumes, dust, gases, insecticides • Mechanical agents – exposure to chronic friction and other mechanical forces may result in crushing, tearing, sprains, dislocations • Social agents – poverty, smoking, abuse of drugs, unhealthy life style, social isolation Host • Human host is referred as soil and the disease agent as seed • Host factors play a major role in determining the outcome of an individual's exposure to infection • Host factors – Demographic - age, sex, race – Biological – genetic factors – Social and economic factors – Lifestyle factors Environmental factors • All that which is external to the individual human host, living or nonliving and with which he is in constant interaction This include all surrounding such as air, water, food, housing etc Physical environment Biological environment Psychological environment Spectrum of Disease Spectrum of health • Health and disease lie along a continuum, • and there is no single cut off point The lowest point on the health-disease spectrum is death and the highest point positive health Positive health Better health Freedom from sickness Unrecognized sickness Mild sickness Severe sickness Death Spectrum of Disease • Variation in the manifestations of disease • Disease spectrum are sub clinical infections (unidentified) to fatal illnesses • Illnesses ranging in severity from mild to sever Iceberg of Disease Iceberg of Disease Iceberg of Disease • Floating tip of the iceberg represents what the physician sees in the community-clinical cases • The vast submerged portion of the iceberg represents the hidden mass of disease- latent, inapparent, presymptomatic and undiagnosed cases and carriers in the community • Water line represents the demarcation between apparent and inapparent disease Prevention Prevention • The goals are To promote health To preserve health To restore health when it is impaired To minimize suffering and distress Levels of Prevention • Primordial Prevention • Primary Prevention • Secondary Protection • Tertiary Prevention Primordial Prevention • Prevention of the emergence or development of risk factors in a population in which they have not yet appeared – Obesity origin in childhood Life styles- eating patterns, physical exercise Main intervention in primordial prevention is through individual and mass education • Directed towards discouraging children from adopting harmful life styles. • example – smoking leading to CPD should be discouraged, Overeating Primary Prevention • Action taken prior to the onset of disease • Removes the possibility the disease will ever occur • Intervention in the prepathogenesis phase of a disease or health problem – Health Promotion – Specific Protection Health Promotion Measures to promote optimal level of health – Provision of adequate nutrition – Health counseling to parents and community – Provision of adequate housing – Health education, counseling – Periodical health examinations – Environmental changes – Provision of safe water – Sanitary latrines – Insect and rodent control Specific Protection Measures applicable to a disease or group of diseases to intercept the cause before the involvement • Specific immunization -Communicable diseases • Specific Nutrient - Nutritional deficiency • Dental carries — Fluoride • Goiter – Iodine • Protection against hazards Cancer– smoking • Chemoprophylaxis Secondary Protection Early diagnosis and prompt treatment • Patient comes in contact with health worker or health facility • Action which halts the progress of a disease at its early stage and prevent complication • Arrest the disease process and restore health • TB- Skin and sputum test Tertiary Prevention • All measures to reduce or limit impairments and disabilities, minimize suffering from disease and to promote the patients adjustment in society Disability limitation – limiting further progress of disability – Measures of prevention at this level is provision of therapeutic substances to arrest the disease and prevent further disability Rehabilitation To train the individual to be useful member Medical rehabilitation Vocational rehabilitation Social rehabilitation Psychological rehabilitation •Occupational therapy •Speech therapy •Audiology •Psychology •Education •Social work •Vocational guidance •Placement services Control Concepts of Control • Disease control • Disease Elimination • Disease Eradication Disease control Aim is to reduce – The incidence of disease – The duration of disease – The effects of infection – The financial burden Disease Elimination Between control and eradication INTERRUPTION of transmission of disease Polio, Measles Disease Eradication – Tear out by roots – Termination of all transmission of infection by extermination of infectious agent – Small pox Universal prevention • Addresses the entire population (national, local community, school, district) • Aim to prevent or delay the abuse of alcohol, tobacco, and other drugs. • All individuals, without screening, are provided with information and skills necessary to prevent the problem. Selective prevention • focuses on groups whose risk of developing • • • problems of alcohol abuse or dependence is above average. The subgroups may be distinguished by characteristics such as age, gender, family history, or economic status. For example, drug campaigns in recreational settings. Polio Indicated prevention • involves a screening process, and aims to • identify individuals who exhibit early signs of substance abuse and other problem behaviors. Identifiers may include falling grades among students, known problem consumption or conduct disorders, alienation from parents, school, and positive peer groups etc. Prophylaxis • Prophylaxis " to guard or prevent beforehand any medical or public health procedure whose purpose is to prevent, rather than treat or cure a disease. • prophylactic measures – primary prophylaxis (to prevent the development of a disease) – secondary prophylaxis (whereby the disease has already developed and the patient is protected against worsening of this process). Prevention is better than cure • Proverbial saying, 17th century • This proverb is often used in relation to health and disease. • It's better to take care that a problem does not happen than to have to solve the problem afterwards. • It's easier to stop something bad from happening in the first place than to fix the damage after it has happened. Latin saying of 13th century It is better and more useful to meet a problem in time than to seek a remedy after the damage is done. ? Yesterday I was clever so I wanted to change the world Yesterday I was clever so I wanted to change the world Today I am wise so I changed myself