Cylindroma
Deba P Sarma, MD
Omaha
F 37, scalp
Cylindroma
Clinical:
Sex: F>M. Location: Mostly scalp. Slow-growing, painful
solitary pink or red dermal nodule about 1 cm in size.
Familial cases associated with multiple tumors. May be
associated with facial trichoepitheliomas, and eccrine
spiradenomas, called autosomal dominant Brooke-Spiegler
syndrome (familial cylindromatosis or turban tumor
syndrome).
Pathology:
Presence of numerous scalp lesions called ‘turban tumor’.
Non-encapsulated dermal tumor not connected to the
overlying epidermis. Composed of lobules of epithelial cells
arranged in a jigsaw or mosaic pattern. Prominent red
basement membrane-like structure encircles the tumor
lobules. Each lobule shows a peripheral lining by dark
basaloid cells and an inner larger and paler zone of cells.
Nodular deposits of red material within the lobules and
focal well-formed ducts. Common adnexal tumor of eccrine
origin.