Rex Moulton-Barrett, MD Lisa Derita, RN Alameda & Brentwood, CA 2007 Sciton Profile Hair Removal Vessel Reduction MicroLaserPeel & Resurfacing Nd-YAG 1064 nm Nd-YAG 1064 nm Er-YAG 2940 nm Er-YAG 2940 nm 2002 Personalized For Your Practice ContourTM 2940nm Er:YAG ThermaScanTM 1319nm Nd:YAG ClearScanTM 1064nm Nd:YAG BBLTM 410-1400nm Intense Pulsed Light New Modules Ablative:MLP, resurface ProFractional: micro-ablative Non-Ablative: acne, vessels Pro-V Non-ablative: collagen Ablative: hair, vessels Non-ablative: collagen Ablative: hair, vessels, pigment Non-ablative collagen, acne 2007 Sciton Profile Hair Removal Hair Removal • • • • Electrolysis Creams Laser Microwave Ideally only destroys source of keratin in hair-bearing skin Regrowth and Removal With Electrolysis Patient: Age, Race, Sex % of Hair Killed Needle Tweezer 21 yr. old white female 27 hairs of 46% 19 hairs or 62% 30 yr. old black female 35 hairs or 30% 22 hairs or 56% 40 yr. old white male 23 hairs or 54% 17 hairs or 66% 53 yr. old white female 36 hairs or 38% 18 hairs or 64% 41 yr. old white female 30 hairs or 40% 22 hairs or 56% Needle = 40%, Tweezer = 60% Average Percent Killed: Laser Hair Reduction Epidermis: 40 - 150 microns Dermis: 140 - 400 microns E & D: 180 >/= 550 microns 1.Papilla: neurovascular tuft 2. Bulge: at Erector Pili 3.Matrix cells:>= 2 mm Anagen> Catogen> Telogen Target Isolation • Can we target over other similar targets? (Can we seek melanin in hair over skin?) Selective Photothermolysis What is the Target ? • Eumelanin: brown or black hair Best absorption of light • Pheomelanin: red or blond hair Poor absorption • Gray hair: pigment-free White hair No absorption Hair Removal Lasers • • • • • Nd:YAG Flashlamp Diode Alexandrite Ruby 1064 575/ 515-1200 800/810 755 694 nm nm nm nm nm Relative Absorption of Laser Light & Competing Chromophores 1064nm Features Wavelength: Power: Fluence: Spotsize: Overlap: Pulsetime: Pulse interval: nm watts power/cm2 mm % ms ms or freq Thermal Containment Time(TCT) re: The Target • The specific time for energy to create reaction without dispersion too short: will not heat to 70 C too long: complete dispersion cooling Determined by pulse width=duration Thermal Relaxation Time(TRT) RE: avoid injury to competing chromophores • Determines the shortest interval between pulses • The time for 51% of heat reduction by dispersion and cooling • proportional to: 1. the square of spot size 2. pulse duration, providing it is > TCT Time of the pulse • Pulse duration should be longer than TCT • and Pulse interval longer than TRT • This commonly protects other components with competing chromophores. Hair Hand Pieces w/cooling Temperature in the Region Near the D/E Junction Versus Cooling Time 40 35 Temperature 30 25 0.1 Sec 0.3 20 1 x 15 10 X 5 0 0 100 200 Depth-microns Skin Surface D/E Junction 300 400 3 Skin Cool Technology Energy Distribution 1 0.8 0.6 Comparison of a 10 mm diameter Gaussian spot with a 6.4 mm diameter square (Top Hat) spot. The square distribution delivers useful energy to a larger spot. Gaussian Top Hat 0.4 0.2 0 -6 -4 -2 0 2 4 6 Pulse Stacking: A Problem With Hand Delivery of Pulses When pulses are applied next to one another, the epidermis heated by the first pulse may still be warm when the second pulse arrives. The “double hit” or “pulse stacking” can result in blisters. The problem will vary with the amount of overlap, which is not well controlled with hand delivery. A model of this effect is shown in the next slide. This is another reason to use a scanner with a large area cooler . With a small fixed window or plate cooler, there is no cooling of the previous spot. Non-sequential scan • The non-sequential scan extends the time between two adjacent pulses to four times the interval of a sequential scan. In combination with the post-pulse cooling, there is adequate time for epidermal cooling. Pulse time? • Treat hair shaft – TCT 6-10 milliseconds • Treat hair follicle – TCT 18-25 milliseconds, ie > 15 ms – TRT 35-60 milliseconds, ie > 35 ms Keys for success •Wavelength: >690 nm (>wavelength=depth) (shorter -> competing chromophores) •Spot size: at least 5 millimeters •Pulse time: 18 or > milliseconds •Pulse interval of 35 or > milliseconds When do you treat? • During Anagen cycle • Not during telogen • Cycle time determined by Richard-Merhag chart Richards-Merhag Fitzpatrick Types OK: Fitzparick IV/VI: Nd-YAG non-confluent scanner >15 ms Continuous cooling Consultation • Patient history • Any previous hair methods • Expectations • Treatment explanation • Photographs • Consent • Periprocedure instructions Contraindications • Pregnancy • Recent sun exposure • Sun tan • Suspicious lesions What about the orbit? Before Treatment • Shave 1-3 days before treatment (stubble) • Avoid other methods for 30 days • SPF 15+ for 4-6 weeks • Avoid tanning creams • Hydroquinone if necessary Treatment Safety • Test cooling plate, check < 5 C • Test spot: and wait 4 weeks • No overlap • Mark landmarks with red pen • Protect gums with Al foil if over area What is the endpoint ? • Small contact spark/flash • Smell of burnt hair • Perifollicular edema • Sensation of light sunburn • One in three hairs extrude Hair Chronology • Redness: 4-6 hours after treatment • Hair appears to grow for several days • Hair falls out: day 10-14 • Hair reappears, next phase: >3-6 weeks • Treat again: >= 6 weeks later Complications of Laser Hair Removal • Blistering • Hypopigmentation • Hyperpigmentation • Scarring Profile System Features • Pulse Length: 0.1 to 200 milliseconds • Wavelength: 1064nm • Fluence: 20 to 120 Joules/cm2 - Hair • • • 30 to 400 Contact Cooling: Power Capacity: Scanning: Joules/cm2 - Vascular Pre, During, Post 200 watts Computer Controlled, Non-sequential Profile Clinical Advantages • • • • • • Maximum Hair Count Reduction Per Treatment Treats All Skin Types Minimal Pain Designed for Safe Operation Highest Speed No overlap required: Top hat pattern of injury Summary of Factors Influencing Success Versus Safety of Therapy •Appropriate settings: fluence ( > 40 J/cm2 ), spot size ( 5mm or greater ), pulse duration ( >18msec ) & pulse interval ( >35msec ) ‘top-hat’ non-sequential scanning •Percentage and density of anagenic hairs •Fitzpatrick skin type: competing chromophore •Percentage of Eumelanin versus red, grey or blond hair •Cooling for at least 3 seconds •Angle of hair follicle ? 1/15 patients, beware of promises Patient Instructions Pretreatment • • Avoid sun exposure 4-6 weeks prior to laser • • Avoid bleaching, plucking, waxing for 4-6 weeks • • Start bleaching regimen 4 weeks prior if tan easily or prone to pigmentation • • Avoid laser interacting medications for at least 10 days prior to laser ( see list ) At time of Laser • • Prep and shave skin with hibiclens • • Protect upper teeth with saline soaked gauze • • Protective external eye shields is used • • No oxygen to be used in same room • • Cooling device is applied to all areas lased: 3 second rule After Laser • • Redness to the skin may last a few hours • • Then resume bleach cream o: 4% hydroquinone with or without sunscreen • • Makeup may be used • • Avoid sun exposure for 6 weeks • • Follow-up and or pretreatment in 4-8 weeks • • Up to 5 treatments to each site may be necessary for permanent hair removal Preoperative Laser Safety Check List Equipment Check • marking pen • pattern sheet • head light • cooling device to 4 degrees C: no bubbles Procedure: • adjust ceiling lights • confirm laser hazard sign on door light and lock door • place protective glasses on pt and all in room • gum protection: moist gauze and Al foil • move laser with arm in locked position to correct position • take key to laser and turn on laser • turn on fan • place on standby • dial desired settings • release arm from lock • perform procedure: maintaining>= 3 second skin contact with cooling devise Examples of Clinical Results Site Fitzpatrick Axilla 4 Axilla/bikini 3 Bikini/thigh 2 Bikini Axilla 4 5 Hair Color Quality black course black course dk brown course black black course course Settings Treatments rate fluence width to satisfaction 5.8 46 35 5 5.9 45 35 5 4.4 60 35 7 3.4 78 35 7 4.6 36 35 5 7.7 30 35 5 Sample Advertisements 400 % variation in local pricing Anticipated Income Income: Low ½ day examples: 95 sideburn n=10 patients 125 underarms 250 thighs 250 forearms 500 lower legs 75 test patch 105 bikini 250 neck 500 lower legs 75 test patch ½ day collection $2225 Full day* collection $3560 * n=16 patients High 400 $5000+ $7120+