Prevention of Catheter Associated Urinary Tract Infections (CA-UTI) Patti G. Grota PhD, RN, CNS-M-S, CIC Nurse Epidemiologist Assistant Professor, UTHSCSA SON Assistant Professor, Schreiner University pgg/06-18-12 Objectives • Explore the epidemiology of CA-bacteriuria. • Discuss national guidelines and recommendations that impact prevention of CA-UTI. • Describe the pathophysiology of CA bacteriuria. • List the differences in asymptomatic CA bacteruria and CA-UTI. • Describe how bundles prevent CA-UTI. • Explain appropriate documentation of indication insertion and maintenance of indwelling urinary catheters. pgg/02-22-12 Epidemiology Problems with Urinary Catheters • Urinary tract infection • Mechanical trauma to urethra and bladder • Immobility (restraining patient)* *Saint S, Ann Intern Med 2002; 137: 125-7 **Saint S, Am J Infect Control 2000;28:68-75 pgg/02-22-12 Epidemiology More Problems • Discomfort and pain to patient • Add to direct costs of hospitalization: $500 to $1,000. If bacteremia present, cost up to $3,800.** • Increased length of stay *Saint S, Ann Intern Med 2002; 137: 125-7 **Saint S, Am J Infect Control 2000;28:68-75 pgg/02-22-12 Epidemiology of CAUTI • Most common type of healthcare-associated infection. 75% diagnosed in a hospital are associated with a urinary catheter *CDC, 2009 pgg/02-22-12 Epidemiology Burden of CA-UTI • The risk of CA-UTI increase 5% every day that an indwelling urinary catheter remains in place.(AACN, 2009) • More than 30 million Foley catheters are inserted annually in the United States, and probably contribute to 1 million CAUTIs . (APIC.org, 2008) • A complications of CA-UTI can increase a patient’s hospital length of stay from 0.4 days to 2 days. (APIC.org, 2008) • An additional average expense of $3,803 per episode, as reported in an ICU CAUTI study. (APIC.org, 2008) pgg/02-22-12 Epidemiology • Indwelling urinary catheters may not always be appropriate – 288 physicians were unaware of the presence of indwelling catheters in 28% of their patients who had catheters. – Less than half of urinary catheters in teaching hospital were indicated. – Catheterization was 3.7 times more likely to be inappropriate if the physician was unaware a catheter was in place. – Approximately 74% US hospitals reported not monitoring how long a catheter had been in place. Saint et. Al Am J Med 2000 Tambyah, Infect Control Hosp Epidemiol 2002;23:27-31 pgg/02-22-12 Pathophysiology Risk Factors for CA-UTI • • • • Method of catheterization Duration of catheter Quality of catheter care Host susceptibility pgg/02-22-12 Pathophysiology: Key Point The risk of CA-UTI increases proportionally with the duration of the indwelling catheter. If you have to use an indwelling catheter, get it out as soon as possible! pgg/02-22-12 Indwelling Catheterization Short term vs Long term • Short-term catheterization Remains indwelling ≤ 2 weeks Commonly used in acute or critical care • Long-term catheterization Remains indwelling ≥ 2 weeks Gray M et al. Best practices in managing the indwelling catheter. Perspectives 2007 (Supp 1) pgg/02-22-12 Pathophysiology Common Pathogens • Endogenous intestinal flora – – – – E. coli Proteus Enterobacter Enterococci • Nonintestinal or environmental pathogens – – – – – Pseudomonas Candida Staph coag neg MRSA Acinetobacter pgg/02-22-12 CAUTI Frequency of Common Pathogens pgg/02-22-12 APIC elimination guide pgg/02-22-12 Pathophysiology Ascension of microbes External (extraluminal) Bacterial Ascension ●Microorganisms colonize the external catheter surface, most often creating a biofilm. ●Bacteria tend to ascend early after catheter insertion suggesting a lack of asepsis during initial insertion. ●Bacteria can also ascend 1-3 days after catheterization, usually due to capillary action. Guide to the Elimination of CAUTIs. APIC, 2008. . pgg/02-22-12 Pathophysiology Ascension of microbes Internal (intraluminal) Bacterial Ascension ●Bacteria tend to be introduced when opening the otherwise closed urinary drainage system. ●Microbes ascend from the urine collection bag into the bladder via reflux. ●Biofilm formation occurs, and damage to bladder mucosa facilitates biofilm on this surface. *APIC.2008. Guide to the Elimination of CAUTIs pgg/02-22-12 CAUTI: Pathophysiology Intraluminal Extraluminal Bladder infection with inflammation Detrusor spasm Leakage Shedding of cells Obstruction (+) UA pgg/02-22-12 Bacteremia Fever Hypotension National Guidelines • Who makes the national guidelines and recommendations? – CDC/NHSN – Infectious Disease Society of America – Joint Commission NPSG 7 – Association of Professionals in Infection Prevention and Control (APIC) – Medicare and Medicaid Regulations pgg/02-22-12 National Guidelines ● Why national guidelines and recommendations? Clinical indicator of quality of care Contributes to increased morbidity, mortality, and costs Increased length of hospital stay Increased patient discomfort Increased risk for hospital readmission *CDC, 2009 pgg/02-22-12 Deficit Reduction Act P.L. 109-171 • Secretary of HHS must identify high cost, high volume preventable conditions that result in higher payment • October 1, 2008 CMS denied payments for 10 hospital acquired conditions (HACs), 3 of which were HAIs Selected surgical site infections Vascular catheter associated infections Catheter associated urinary tract infections pgg/02-22-12 Joint Commission NPSG 07.07.01(adults only) • Implement evidence-based practices to prevent indwelling catheter associated UTI (CAUTI) pgg/02-22-12 CAUTI Bundle Components Insertion Maintenance Surveillance pgg/02-22-12 What is a bundle? • A collection of best practices identified by evidence-based science as necessary to provide optimum care for patients in certain circumstances involving particular risks to achieve the goal of improved outcome. • Keep It Smart but Simple Hand hygiene Aseptic technique Secure the catheter Check daily for removal Closed drainage system Appropriate indication pgg/02-22-12 “Life Cycle” of the Indwelling Urinary Catheter Catheter Placement Catheter Replacement Catheter Care Catheter Removal pgg/06-18-12 Disrupting the Life Cycle of the Indwelling Urinary Catheter Prevent unnecessary placement Maintain proper care Prevent catheter replacement Promptly remove catheter pgg/06=18-12 What does the evidence say? Category 1 Strongly Recommended* • • • • • • • • • Educate personnel in correct techniques Catheterize only when necessary Leave catheter in the least amount of time possible Hand washing principles Sterile technique Secure catheter properly Maintain closed sterile drainage Obtain urine samples aseptically Maintain unobstructed urine flow pgg/02-22-12 CDC, 2009 Appropriate Indications for Insertion • • • • • • • Hospice Care Neurogenic bladder Obstruction/retention Stage 3 or 4 pressure ulcer Selected surgical procedures Critically ill pt to monitor urine output Prolonged immobilization ~Indications based on expert consensus pgg/02-22-12 Inappropriate Indications • Nursing care of incontinent patients • A means of obtaining a urine specimen when the patient can voluntarily void • Prolonged postoperative duration without indications pgg/02-22-12 Alternatives To Insertion External Urinary Catheter Devices Intermittent catheterization Bladder scanners pgg/02-22-12 Advantages of Suprapubic Catheterization • Lower risk of CA-bacteriuria • Reduced risk of urethral trauma and stricture • Ability to attempt normal voiding without the the need for recatheterization • Less interference with sexual activity (Cochran Review of 14 trials that compared indwelling with suprapubic) pgg/02-22-12 CAUTI Bundles Maintenance • Maintain sterility of closed urinary drainage • Maintain unobstructed urinary flow • Keep collection bag below the bladder and off the floor • Do not change indwelling catheters or collection bags routinely • Wash hands prior to handling the urinary drainage system and catheter pgg/02-22-12 Maintain Proper Care • Hand hygiene immediately before and after insertion and before any manipulation of the catheter device • Use smallest bore catheter possible • Indwelling urinary catheter must be properly secured to prevent movement or urethral traction. • Date the Foley collection bag with permanent marker or label pgg/02-22-12 CAUTI Bundles Maintenance • Check the skin condition around the securement device at least daily. Relocate if irritation of skin is noted. • Use port for urine collection-Do no break catheter system to collection specimen. • For long-term indwelling catheters, change the catheter prior to specimen collection. • Remove the catheter as soon as possible. pgg/02-22-12 Strategies for Monitoring Catheter Use by Setting Setting Strategies References Emergency Department Indication checklists, tagging of catheter bags Gokula, 2005 ICU Daily checklists for indication Huang, 2004 Jain, 2006 Reilly, 2008 Peri-procedure Aseptic procedures for catheter placement, Automatic stop orders Stephen, 2006 General Admissions Reminders vs stop orders, daily checklists for indication Saint, 2005 Topal, 2005 Crouzet, 2007 Fakih, 2008 pgg/06-18-12 Early Removal of Indwelling Catheters: Summary of the Evidence • 14 studies have evaluated urinary catheter reminders and stop-orders (written, computerized, nurse-initiated) – Significant reduction in catheter use – Significant reduction in infection – No evidence of harm (ie, re-insertion) (Meddings J et al. Clin Infect Dis 2010) pgg/02-22-12 Removal of catheters: Additional principles • Remove as soon as possible after insertion • Use a portable ultrasound device to assess urine volume in patients before catheterizing to determine need. • Use a portable ultrasound device to assess for retention after removal of indwelling catheter and prior to reinsertion. pgg/02-22-12 CAUTI Bundle Caution C-Closed System, Catheter Selection, Consider Alternatives A-Aseptic Management U-Universal/Standard Precautions T-Tie/Secure Catheter to patient/Tubing to bed I-Indications for Use AND to Discontinue O-Obstruction Free, Specimens from Sampling Port N-No Dependent Loops *CDC, 2009 pgg/02-22-12 Cochrane Review of Antimicrobial Catheters (2008) • 23 trials involving 5236 hospitalized adults in 22 parallel group trials met inclusion criteria • Conclusion #1: “…Silver alloy (antiseptic) coated or nitrofurazone impregnated (antibiotic) urinary catheters might reduce infections in hospitalized adults…..but the evidence is weak. • Conclustion #2: “Larger, more scientifically rigorous, trials are needed on whether catheters impregnated with antibiotics or antiseptics reduce infections. pgg/02-22-12 Antimicrobial Catheter Recommendations (CID, 2010:50) • Short-term indwelling urethral catheters: May reduce onset of CA-bacteriuria but data is insufficient to support reduction of CA-UTI • No trial has compared antibiotic-coated versus silver alloy-coated catheters • No indication supported in long term indwelling urethral catheters. pgg/02-22-12 CA-bacteruria or CA-UTI How do you know? • CA-UTI will be accompanied by signs and symptoms with no other probable cause – Fever – Suprapubic tenderness – Acute hematuria – Altered mental status – Dysuria – Urgency pgg/02-22-12 NHSN CA-UTI Surveillance Definitions Criterion 1a Indwelling urinary catheter in place at the time of specimen collection or removed within the 48 hours prior to specimen collection Positive urine culture with no more than 2 pathogens At least one sign or symptom with no other cause Costa vertebral angle pain or tenderness Suprapubic tenderness Fever> 38 degrees C pgg/02-22-12 NHSN CA-UTI Surveillance Definitions Criterion 2a Indwelling urinary catheter in place at the time of specimen collection or removed within the 48 hours prior to specimen collection At least one sign or symptom with no other cause A positive urinalysis demonstrated by at least 1 of the following: Costa vertebral angle pain or tenderness A + dipstick for either leukocyte esterase or nitrites Suprapubic tenderness Pyuria Fever> 38 degrees C Microorganisms seen on Gram stain of unspun urine pgg/02-22-12 A positive urine culture of > 103 and < 10 5 colonyforming units/ml with no more than 2 species of microorganisms Pyuria alone is NOT indicative of a CA-UTI. pgg/02-22-12 Foley Data Collection Tool LEGEND: X - Foley Present; BLANK CELL - No Foley Present; D/C - Foley Discontinued; R - Foley Replaced; 4/30 4/29 4/28 4/27 4/26 pgg/02-22-12 4/25 X X X X D/C 4/24 OR 4/23 EXAMPLE 1111 4/1/10 4/22 C ensus 4/21 4/20 4/19 4/18 4/17 4/16 4/15 4/14 4/13 4/12 4/11 4/10 4/9 4/8 4/7 4/6 4/5 4/4 4/3 4/2 4/1 Location R 24 - Foley discontinued but replaced due to retention within 24 hours Patient's of Foley Last 4 of Foley Insertion Patient's Last Social Insertion (if known) Name Security Date Number SI/ C T IC U Please print clearly. Indicate date of insertion with a “V”. Please mark each day of catheter with an “X” Please indicate “DC” on the date catheter is discontinued. EP: CAUTI Rates • Metric #1: Number of foley catheters per unit per day (nursing) • Metric #2: Number of foley catheter days per unit per month (nursing) • Metric #3: Number of CA-UTI per unit (IC) pgg/02-22-12 IPEC Data Entry Symptomatic CAUTI pgg/02-22-12 IPEC Compliance Reporting pgg/02-22-12 Documentation: Procedure Note • • • • • • • • • • • • Note title: INSERTION OF INDWELLING URINARY CATHETER (Template note) Bladder scan prior to insertion: Yes ____________ No____________________ If yes, amount of urine return: (free text) Type of procedure: Intermittent (In and Out)____ Indwelling________ Type of insertion: Initial ________ Reinsertion_______ Catheter description: Type (use drop down box) Size (use drop down box) Hand hygiene and aseptic technique were used by inserter. Yes No Catheter was properly secured. Yes No Collection bag placed below the level of the bladder. Yes No Inserted without difficulty. Yes No If No, describe process Amount of urine return: (free text) pgg/02-22-12 Documentation Daily Maintenance Note (new) • Note title: Urinary catheter Daily Care (Daily assessment note for units who do PIE notes) • Urinary drainage device Yes No • If yes, what type (drop down box): IUD_________ ICC__________ Suprapubic________ EUD_________ Dialysis________ • Other(free text)_________ • Sterile, continuously closed drainage system maintained (if appropriate) Yes No • If indwelling urinary catheter or EUD, catheter properly secured Yes No • Unobstructed urine flow maintained. Yes No • Drainage spigot not allowed to touch the collection container. Yes No • Meatal care provided with routine hygiene. Yes No pgg/02-22-12 Documentation Nursing Admission Assessment • Bladder elimination: Denies problems Unable to assess. Urinary catheter device pgg/02-22-12 Has urinary catheter device • If checked, urinary catheter template opens up (see below) What type of device(drop down box): IUD_________ ICC__________ Suprapubic_______ EUD_________ Dialysis__________ Other(free text)_________ • Catheter changed on admission using aseptic technique: Yes No • Sterile, continuously closed drainage system maintained (if appropriate) Yes No • If indwelling urinary catheter or EUD, catheter properly secured Yes No • Description of urine: (drop down box) clear, turbid, hematuria • Signs of CA-UTI: (drop down box). (Check all that are appropriate) oliguria, dysuria, hematuria, suprapubic pain, intervertebral coastal pain, fever , confusion pgg/02-22-12 HOW ARE YOU DOING? Example compared to NHSN Mean National Healthcare Safety Network (NHSN) Report, data summary for 2006 through 2007, issued pgg/02-22-12 November 2008. HOW ARE YOU DOING? Example compared to NHSN 10 per centile National Healthcare Safety Network (NHSN) Report, data summary for 2006 through 2007, issued pgg/02-22-12 November 2008. PROMOTING COST SAVINGS AND IMPROVED PATIENT CARE • Direct predicted costs of one CAUTI= $3800 • Predicted Direct Costs for CAUTI annually= N X $3800; where N = number of CAUTI • Indirect costs= lost work time, patient suffering etc. pgg/02-22-12 What can you do? • • • • • Staff Education and Competencies Nurse Champions Policies and Procedures Documentation Team Ownership pgg/02-22-12 Thank you!! pgg/02-22-12