What We Need is a Red Book for College Health: Infection Control for the College Campus Evelyn Wiener, MD University of Pennsylvania 1 United States Environmental Protection Agency Public Health Image Library 2 SESSION OBJECTIVES • List communicable diseases for which infection control measures are indicated • Identify modes of transmission for communicable diseases • Identify appropriate infection control measures for common and/or serious contagious diseases • Know the campus and community resources involved with implementing infection control measures 3 LA 2/23/12 • History: – Sore throat & cough x 1 day – PMH pneumonia one year ago • Physical exam – BP 138/85 HR 115 T 98.5 – Pharynx red, TM normal – Lungs clear • Symptomatic treatment advised 4 LA, continued Returns 2/28/12 • CXR (obtained 2/23) was negative • Symptoms have continued, cough worse • Physical exam – BP 147/91 HR 113 T 99.0 – Pharynx red, cervical adenopathy – Lungs clear, but frequent dry coughing fits, speaking in full sentences • Symptomatic measures continued 5 LA, continued 2/29/12 • Goes to ER - cough incessant, uncontrolled by codeine • What is the differential diagnosis? • What else do you need to know? • What do you need to do? 6 WHAT NOW? What are the infection control issues? Which issues are unique to college setting? Who needs to be involved/informed? Where do you find the answers? 7 Family FAMILY PARTNERS HEALTH SERVICE STUDENT ADMINISTRATION FRIENDS STUDENT AFFAIRS RES LIFE STAFF FACULTY Risk Management ROOM MATES CLASS MATES Environmental Health FACILITIES HUMAN RESOURCES 8 WHAT DO STUDENTS NEED TO KNOW?* *Also parents, staff, media • Who is at risk for exposure? • What should students do if they were exposed? • What should students do if they have symptoms? 9 WHAT DO ADMINISTRATORS NEED TO KNOW? • Same as students PLUS • • • • • Extent of outbreak Measures needed to control outbreak Need to provide support to affected students Need for resources Talking points 10 WHAT DO CLINICAL STAFF NEED TO KNOW? • Same as students and administrators PLUS • • • • • On-site infection control measures Clinical presentation Diagnostic tests Management Reporting 11 CAMPUS INFECTION CONTROL ISSUES • How do basic infection control principles apply in a campus environment? – Populations – Facilities – Significant functions • What resources are needed? • What resources are available? 12 STUDENT POPULATIONS Residential students Commuters Part-time students Greek system Athletes Health care students International students Visiting/exchange students 13 OTHER POPULATIONS Faculty Staff Visitors Special program participants Contractors 14 FACILITIES Student housing Residence halls Fraternities and sororities Off-campus housing Dining halls Classrooms Research laboratories Libraries Athletic facilities Other buildings 15 SIGNIFICANT FUNCTIONS Students Faculty Administration Classes Classes HR/personnel Research Research Finance/payroll Housing Advising Facilities Dining Information systems Activities Business services Work Public safety 16 TYPES OF INFECTIOUS DISEASES Viral Bacterial Fungal Parasitic Nematodes and helminths Critters 17 TRANSMISSION BASICS • • • • • Airborne Droplet Contact Ingestion Blood and body fluid 18 AIRBORNE TRANSMISSION • Airborne droplet nuclei – Small particles <5 μm of evaporated droplet • Widely dispersed • Remain suspended in air for long periods • Indication for N95 respirator 19 TB Online CDC CDC 20 DROPLET TRANSMISSION • Droplets generated primarily by coughing, sneezing, talking • Droplets relatively large – Propelled short distance (< 3 feet) – Deposited on conjunctiva, nasal mucosa, mouth – Do not remain suspended in air • Indication for surgical masking 21 CDC CDC CDC scarletfeverpictures.com 22 CONTACT TRANSMISSION • Direct contact with infected area • Fomites • Most common route of health care-associated infections 23 Wikipdedia/Robert Morley CDC/Dr. Thomas Sellers CDC MiteBitespictures.com 24 INGESTION Chicago Star Tribune 25 BLOOD AND BODY FLUID CDC CDC 26 CONTROL AND PREVENTION • Pre-exposure immunization (for vaccine-preventable diseases) • Screening • Hand hygiene • Food and water safety • Universal precautions • Isolation and quarantine • Post-exposure immunization • Post-exposure chemoprophylaxis 27 RECOGNIZING AND MANAGING OUTBREAKS • • • • • Disease surveillance Contact identification and tracing Pre- and post-exposure prophylaxis Notification Public health emergencies 28 INFECTION CONTROL ISSUES • • • • • Transmission characteristics Diagnosis Treatment Evaluation of the exposed individual Control measures • Isolation/exclusion – who, what, how long • Post-exposure measures • Environmental measures 29 PERTUSSIS Manifestations Catarrhal stage Cough {Total duration 6 – 10 weeks} Paroxysmal stage Transmission Droplet Incubation period Typically 7 – 10 days (range 6 -21 days) Diagnostic tests Culture PCR DFA Treatment Macrolide antibiotic (azithromycin) Infectivity From onset of symptoms* to 2 weeks after onset of paroxysms 30 PERTUSSIS, continued Isolate student until first five days antibiotics completed or until 21 days after onset of Control measures symptoms Isolate symptomatic contacts Candidates for Prophylaxis indicated for household and post-exposure other close contacts measures Monitor for 21 days after last contact Post-exposure measures Macrolide antibiotic (azithromycin) Update Tdap when indicated, but not effective as post-exposure measure Cleaning and disinfecting Routine cleaning only 31 MEASLES Manifestations Transmission Fever, followed by cough, coryza, conjunctivitis and Koplik spots Erythematous maculopapular rash, starts on head and spreads downward Airborne spread, as well as direct contact with infectious droplets Incubation period 8 to 12 days Diagnostic tests Culture, serology, RT-PCR Treatment No specific antiviral therapy Infectivity Highly infectious Contagious from four days before onset of rash to four days after rash appears 32 MEASLES, continued Isolate for 4 days after onset of rash (airborne precautions) Control measures Isolate symptomatic contacts Consider excluding asymptomatic contacts who cannot demonstrate immunity Candidates for post-exposure Anyone who cannot demonstrate immunity measures Post-exposure measures Post-exposure immunization may be effective if given within 72 hours of exposure Cleaning and disinfecting Routine cleaning only 33 MRSA Manifestations Pustule or boil, commonly at site of visible skin trauma Transmission Contact Diagnostic tests Culture and sensitivity Treatment Incision and drainage Empiric antibiotics may be warranted When possible, obtain specimens for C&S to guide continued antibiotic choice 34 MRSA, continued Cover infections Exclude athletes if wounds cannot be properly covered Control measures Hand hygiene Clean shared equipment Do not share personal items Post-exposure measures No specific measures Cleaning and disinfecting Usually routine cleaning sufficient Focus on surfaces that might come in contact with uncovered infections Clean shared equipment Routine laundry procedures 35 NOROVIRUS Manifestations Diarrhea and vomiting Symptoms last 1 – 14 days Transmission Ingestion Person-to-person (fecal-oral) Contaminated food or water Incubation period 12 to 72 hours Diagnostic tests PCR assays not commercially available Treatment Symptomatic – antiemetics, rehydration Infectivity Most contagious during symptoms and first 3 days of recovery 36 NOROVIRUS, continued Standard measures for control of diarrhea Scrupulous hand hygiene Control measures Exclude infected individuals from food preparation, health care, child care Consider isolation for 48 hours Candidates for Reinforce hand hygiene to anyone with post-exposure potential exposure measures Post-exposure measures No specific measures available Cleaning and disinfecting Disinfect contaminated surfaces with bleach solution or other disinfectant Wash contaminated clothes and linens 37 AIRBORNE DROPLET CONTACT INGESTION BLOOD/FLUID Measles Pertussis MRSA Norovirus HIV Chickenpox Mumps Impetigo Hep A Hep B Zoster Meningococcus Scabies Campylobacter Hep C Tuberculosis Influenza Salmonella SARS Strep pyogenes C. diff Shigella Smallpox Rubella Fungi E. coli Monkeypox Adenovirus Adenovirus Mycoplasma Zoster HSV 38 OTHER ISSUES • Global health concerns • Global patterns of disease • Issues for students traveling abroad • Issues for international students • Health care students • Animal-borne diseases • Faculty and staff 39 ENVIRONMENTAL CLEANING Standards for cleaning Cleaning in response to disease outbreak Special circumstances/setting Protective equipment 40 CAMPUS RESOURCES • • • • • • • SHS Dean of students Environmental Health Public safety Facilities Human Resources Risk Management 41 COMMUNICATIONS • • • • • Communication with administration Communications to students (and parents) Communications to faculty Media releases Notification to public health officials 42 ACKNOWLEDGEMENTS Sharon McMullen RN BSN BA University of Pennsylvania Esther Chernak, MD, MPH, FACP Drexel University School of Public Health 43