Automatic Vein Pressure Measurement using Ultrasound Orçun Göksel Vincent Baumann Computer Vision Laboratory ETH Zürich VeinPress GmbH Central Venous Pressure (CVP) Blood pressure in thoracic vena cava, near right atrium Amount of blood returning to the heart Ability of the heart to pump the blood into the arterial system CVP for monitoring hemodynamics Preload Volume overload Cardiac failure Sepsis … Bern, 02.09.2014 CTI MedTech Event: Venous Pressure Measurement 2 Conventional Measurement Catheterization of subclavial or internal jugular vein Bern, 02.09.2014 CTI MedTech Event: Venous Pressure Measurement 3 Our Technique Bern, 02.09.2014 CTI MedTech Event: Venous Pressure Measurement 4 Automatic Measurement Device Bern, 02.09.2014 CTI MedTech Event: Venous Pressure Measurement 5 Measurement Process Bern, 02.09.2014 CTI MedTech Event: Venous Pressure Measurement 6 Under the Hood Noisy compression data (a) Robust detection (b) (c) Statistical and Model-based processing Bern, 02.09.2014 CTI MedTech Event: Venous Pressure Measurement Multiple candidates 7 Results Preliminary Study * Clinical study is ongoing at University Hospital Basel, Angiology Clinic (led by Dr. med. Stephan Imfeld) Bern, 02.09.2014 CTI MedTech Event: Venous Pressure Measurement 8 Bern, 02.09.2014 CTI MedTech Event: Venous Pressure Measurement 9 Why VeinPress Method Bern, 02.09.2014 Catheter VeinPress Invasive Non-invasive CTI MedTech Event: Venous Pressure Measurement 10 Why VeinPress Method Complications Bern, 02.09.2014 Catheter VeinPress Invasive Non-invasive Severe and several None CTI MedTech Event: Venous Pressure Measurement 11 Why VeinPress Method Complications Time Bern, 02.09.2014 Catheter VeinPress Invasive Non-invasive Severe and several None >20 minutes 1 minute CTI MedTech Event: Venous Pressure Measurement 12 Why VeinPress Method Complications Time Personnel Bern, 02.09.2014 Catheter VeinPress Invasive Non-invasive Severe and several None >20 minutes 1 minute Trained physician +assistant A nurse CTI MedTech Event: Venous Pressure Measurement 13 Why VeinPress Method Complications Time Personnel Material cost / procedure Bern, 02.09.2014 Catheter VeinPress Invasive Non-invasive Severe and several None >20 minutes 1 minute Trained physician +assistant A nurse CHF 250+ Minimal CTI MedTech Event: Venous Pressure Measurement 14 Why VeinPress Non-invasively The only validated method No Complications Benefit to patient 90% cost reduced Benefit to Healthcare System Bern, 02.09.2014 CTI MedTech Event: Venous Pressure Measurement 15 Potential Medical Applications Research tool Clinical focus areas: Venous diseases, e.g. thrombosis Urgency: Bleeding, sepsis, volume overload Chronic brain edema in low gravity Others Bern, 02.09.2014 CTI MedTech Event: Venous Pressure Measurement 16 Ongoing Projects ETH Computer Vision Lab Prof. Dr. Orcun Göksel NASA, Houston (USA) Dr. Dean Martin Head of Ultrasound 1 2 University of Basel (CH) Dr. med. S. Imfeld Dr. med. M. Aschwanden Angiology Clinic University of Zurich (CH) PD Dr. med. Ch. Thalhammer Angiology Clinic 3 6 University of Toulon (FR) Starting in 11/2014 Bern, 02.09.2014 55 University of Bari (I) Prof. C. Caiati CTI MedTech Event: Venous Pressure Measurement 4 17 VeinPress Team Dr. Markus Widmer Engineering Dr. med. Ulrich Baumann Medical Vincent Baumann Legal Bern, 02.09.2014 Dr. med. Eric Odenheimer Production / Sales CTI MedTech Event: Venous Pressure Measurement 18 Looking into the Future Bern, 02.09.2014 CTI MedTech Event: Venous Pressure Measurement 19 We would like to thank… CTI Wirtschaftsförderung, Kanton Bern ETH Zurich, Computer Vision Lab Patrick Roth, CCMT All clinical partners Prof. em. Kurt Jäger Bern, 02.09.2014 CTI MedTech Event: Venous Pressure Measurement 20 Thank you! for your vote Stay tuned @ www.veinpress.com Questions?