Pediatric Trauma: A Primer Author: Carla Angelski, MD, FRCPC, Assistant Professor, University of Toronto Date: December 2011 Glo bal H ealth E me rge ncy M edicineTeachi ng Modu les by GH EM is license d u n der a C reativ e C o mm ons A ttrib utio n-No nC om me rcial -ShareAlike 3.0 Un p ort ed License . Learning Objectives The student should understand the utility and benefit of the primary and secondary surveys The student will describe adjuncts of the primary and secondary survey and when to use them The student should gain exposure to general categories of pediatric trauma The student will understand that pediatric trauma is above all preventable Epidemiology1,2 25% of traumatic injuries occur in children Trauma is the leading cause of death after infancy (age 1-14y) Epidemiology2,3,4 Most common causes of injury-related deaths: Traumatic brain injury Motor vehicle crashes Submersion injury Homicide Suicide Fires Epidemiology2,3,5,36 Data from 2002 shows > 700 000 injury-related deaths world-wide occur in the <15 year old age group Bimodal distribution in injury death rates: Children and Teens Teens are at increased risk due to: Increased exposure to hazards Risk-taking behaviors Infants: Are at higher risk of inflicted trauma Epidemiology3,5,6,7 Males at higher risk of death from ALL injury types Minority and low-income children at higher fatal and non-fatal rates of traumatic injury Epidemiology3 Pediatric specific trauma centers first developed in 1970’s in North America Children at these centers do better than predicted by trauma triage scores Trauma triage scores were developed to predict which patients require trauma center care Can assist physicians in determining level of triage Trauma Triage Scores3, 8-11 Examples include: Revised Trauma Score (RTS) Pediatric Trauma Score (PTS) Injury Severity Score (ISS) Prevention3,12,13 Trauma has patterns and risk factors Identifying high-risk populations can help target interventions Examples: Seatbelts Car Seats Helmets (for bicycle riding) Fire Safety courses Swimming lessons Emergency Preparedness14,15,16 Broselow© specific crash cart Broselow© tape Equipment and medication stocked as per published guidelines Consider Canadian guidelines: http://www.cps.ca/english/statements/cp/cp09-03.htm Or American Guidelines http://www.acep.org/content.aspx?id=29134 Or Australian standards for resuscitation: http://www.resus.org.au/clinical_standards_for_resuscitation_m arch08.pdf http://www.cps.ca/english/statements/cp/cp09-03.htm http://www.cps.ca/english/statements/cp/cp09-03.htm http://www.cps.ca/english/statements/cp/cp09-03.htm http://www.cps.ca/english/statements/cp/cp09-03.htm PRIMARY AND SECONDARY SURVEYS Primary & Secondary Survey3,17 Primary survey: Quick, initial patient assessment to identify lifethreatening injuries Occurs with active resuscitation Secondary survey: More detailed assessment of injuries Primary Survey3 A,B,C,D,E Every trauma patient should arrive boarded and C-spine immobilized Collar for school-age/adolescents Rolls and tape for infants/toddlers Immediate vitals signs A,B,C,D,Es A = Airway & C-Spine Precausions B = Breathing C = Circulation D = Disability E = Exposure A: Airway & C-Spine Protection3 Check for airway patency and clear secretions such as: Blood, foreign bodies, loose teeth Assess need for intubation If there are facial burns that extend to the mouth or signs of inhalation injury – INTUBATE EARLY! Ensure adequate C-spine protection C-Spine Injuries3 Overall rare Associated with 1.2% of pediatric trauma After 8y, spine anatomically similar to adult Children <14y = injury C1-C4 more common Fulcrum immature spine C2-C3 Children >14y = injury C5-C7 more common Fulcrum mature spine C5-C6 B: Breathing3 Check for adequacy of breathing Effort, breath sounds, oxygenation Apply oxygen by facemask or blowby Consider need for intubation If already intubated confirm ETT position with: Chest x-ray if available End tidal CO2 or pedi-cap if available Oxygen saturation if available Auscultate the lungs for equal air entry Take a look with a laryngoscope C: Circulation3 Most common cause of shock in pediatrics = hypovolemia TBV of child = 80ml/kg 2 large bore IV’s started Xmatch or Type and screen ordered 20 ml/kg IV crystalloid bolus (x 3 then PRBC’s) Look for obvious and non-obvious sources of bleeding D: Disability3 Pupils reactive? Equal? GCS (modified) or Verbal Score Spontaneously moving? Obvious deformities? Pediatric Verbal Score Verbal Response V-Score Appropriate words/coos Smiles, fixes/follows 5 Cries but consoles 4 Persistently irritable 3 Restless, agitated 2 None 1 From American College of Surgeons’ Committee on Trauma. Advanced Trauma Life Support for Doctors (ATLS) Student Manual . 7th ed. Chicago: American College of Surgeons; 2004. Glasgow Coma Scale (GCS)3 Eye Opening Spontaneous 4 To voice 3 To pain 2 None 1 Verbal Response (Peds) Appropriate 5 Cries, consoles 4 Persistently irritable 3 Restless, agitated 2 None 1 Motor Response Obeys Commands 6 Localizes pain 5 Withdraws to pain 4 Flexion with pain 3 Extension to pain 2 None 1 E: Exposure Assess all surface areas Log-roll with using spinal precautions Examine the spine: note step deformities or pain Assess rectal tone and sensation Check for vaginal/urethral bleeding Prevent hypothermia Keep trauma room warm, use blankets and overhead warmer for infants History3 Ask about the Mechanism of injury: Speed, distance thrown, fall from height, landing surface, accident? What protective devices used? Seatbelts, carseats, helmets What were the initial findings and vitals on scene (if available) Primary Survey Goals13 IDENTIFY INTERVENE Airway Inadequate airway Secure and protect Breathing Apnea Positive pressure ventilation Hypoxia Supplemental oxygen Tension pneumothorax Needle decompression, chest tube Massive hemothorax Chest tube Open pneumothorax Occlusive dressing, chest tube Primary Survey Goals13 IDENTIFY INTERVENE Circulation Hypovolemic shock Fluid bolus, blood products Pericardial tamponade Fluid bolus, pericardiocentesis, thoracotomy Cardiac Arrest Chest compressions, thoracotomy if penetrating trauma Disability Spinal cord injury Immobilization Cerebral herniation Hyperventilation, mannitol Exposure Hypothermia Warmed fluid, external warming Exsanguinating hemorrhage Direct pressure Adjuncts to Primary Survey3 Access: Intravenous or Intraosseous needles Monitor: Cardiorespiratory/Pulse oximetry; size appropriate blood pressure cuff Imaging (x-rays) Trauma bloodwork CBC, electrolytes, blood gas, creatinine, BUN, PT/PTT, Xmatch, liver function studies, lipase or amylase BHCG if female of child-bearing age Consider Toxicology screen and cardiac enzymes if appropriate Imaging Prior to Secondary Survey Xrays: CXR (AP only) Pelvis (AP only) C-spine: lateral, AP and odontoid if cooperative Secondary Survey Head to toe examination Tetanus status IV antibiotics if necessary AMPLE history: allergies, medications, past medical history, last meal, events surrounding injury Vascular Access - The IO Needle3 If unable to secure access in 90 seconds = IO Provides immediate vascular access when needed Safe to administer fluids, drugs, blood products Can be left for up to 72h Use until more secure vascular access The IO Needle: Relative Contraindications3 Underlying fracture Overlying infection Previous attempt at same site Osteogenesis Imperfecta Procedure 14 to 20 gauge IO needle with stylus (or EZ IO gun if available) Prepare area in sterile fashion and use local anesthetic Landmarks: Proximal medial aspect of tibial plateau, 1-2cm distal to tuberosity (aiming away from growth plate) Distal femur, 1-2cm proximal to superior border of patella Procedure3 Insert needle at 900 angle to bony surface Avoid putting hand behind limb where IO inserted Slowly twist after puncturing the skin until ‘release’ is felt You may or may not aspirate marrow, this is not always possible or necessary Connect to IV tubing Secure to skin with tape and gauze IO Insertion http://emedicine.medscape.com/article/940993-overview Head Trauma Head Trauma3,18,19,20 Head trauma is the leading cause of death & disability in childhood Mortality rate 20-30% 0-14y age range TBI = 400 000 visits/year to ED 1-2% of all comers to ED Only 3-5% of those with intracranial injury <1% of above require neurosurgery Head Trauma21 Epidemiological/Environmental factors: Infancy: NAT, falls Childhood: MVA, pedestrian, bicycle Adolescence: MVA, pedestrian, bikes/boards, violence Sex: M = F ~ 5 yo M > F > 5 yo (2-5:1) Head Trauma: Pathophysiology Cerebral blood flow depends on both autoregulation and the Central Perfusion Pressure CPP = MAP – ICP If autoregulation is lost, CBF is solely dependant on CPP If the ICP increases secondary to an intracranial injury (for example a bleed), a time will come when the MAP cannot overcome the resistance provided by the ICP, and cerebral perfusion will slow down Age Related Differences21 Anatomical age related differences: Children have larger heads compared to body ratio Higher water content (88% vs 77%) softer, prone to acceleration-deceleration injury Water content inversely proportional to myelinization More susceptible to shear injuries Open sutures – tolerate higher ICP better Common Signs & Symptoms of Increased ICP in Children22 Full fontanel Splitting sutures Altered state of cosciousness Paradoxical irritability Persistent emesis Cranial nerve paralysis Papilledema Cushing’s Triad: Hypertension, bradycardia and hyperventilation Decorticate or decerebrate posturing Etiology3 Diffuse axonal injury more common in children than adults Require less neurosurgical intervention Epidural hematomas are a neurosurgical emergency – most often follow trauma to temporal region Consider if period of LUCIDITY followed by deterioration Subdural hematomas – be suspicious for nonaccidental Trauma (NAT) if no history of trauma Acute Medical Management of Raised ICP3,13 Position head of bed at 300 Mannitol IV 20% = 1g/kg per dose Must chase with bolus of NS Prevent hypoxia and hypotension CPP = MAP – ICP Focus on maintaining MAP’s with IV fluids Control external hemorrhage Maintain C-spine precautions Early intubation using RSI to prevent complications Rapid Sequence Intubation of the Head Injured Child 3,23,24 Consider pre-treatment with Atropine if <1yo Consider pre-treatment with Lidocaine at least 5-10 minutes prior to intubation Thiopental 2-4mg/kg, Propofol 1mg/kg, fentanyl 13mcg/kg or etomidate 0.3mg/kg all appropriate choices Know adverse events associated with each before you use them! MUST maintain CPP therefore ensure adequate PRELOAD with IV fluids Succinylcholine or Rocuronium for paralysis Head Injury Definitive management dependant on lesion and examination Early involvement of neurosurgery recommended Admission for observation and closely monitoring for deterioration a must Consider need for IV Mannitol early for raised intracranial pressure Chest Trauma Chest/Thoracic Trauma3,25 Accounts for 4.5 – 8% pediatric trauma 2nd most common cause of mortality in pediatric trauma Most common causes: Motor vehicle accidents (MVA’s) Pedestrians Unrestrained passengers Bicycle riders Falls Chest/Thoracic Trauma3 Pediatric thoracic trauma higher risk: More compliant chest wall Increased mediastinal mobility Tension pneumothorax develops quicker Children more prone to hypoxia Less ability to compensate for hypovolemia Chest/Thoracic Trauma3,26 Blunt versus penetrating Blunt: High energy trauma affects internal organs Deceleration mechanisms affect mediastinal structures Penetrating: Disrupts underlying structures Do not remove penetrating objects! Must remove in a controlled setting (Operating Room) Chest/Thoracic Trauma Consider: Hemothorax Pneumothorax (+/- Tension Pneumothorax) Flail chest Diaphragmatic ruptures Bronchial/Tracheal tears Esophageal ruptures Pulmonary contusions Commotio Cordis Cardiac tamponade Tension Pneumothorax Hypotension, distended jugular veins, shifted heart sounds, hyper-resonance, trachea not midline Treatment: Emergent needle decompression = Large bore IV inserted over rib in 2nd ICS after sterile drape/prep if possible Consider 3-way stopcock to continue drawing off air Chest tube needed for definitive management Chest Tube Insertion For an approach to chest tube insertion: Mikrogianakis A et al. The Hospital for Sick Children Manual of Pediatric Trauma. 1st ed. Philadelphia: Lippincott Williams & Wilkins; 2008: 258-262. http://flylib.com/books/en/2.569.1.21/1/ Abdominal Trauma Abdominal Trauma3,22 3rd leading cause of traumatic death Often unrecognized in children Consider abdominal injury in the following: Sign Possible Injuries Seatbelt Injury Small bowel injury Chance fracture Handlebar injury Duodenal hematoma Pancreatic injury Sport related injury Spleen, kidney, bowel Abdominal Trauma3,27,28 What are the odds of having intraabdominal injury? Based on the Abdominal Exam: Tenderness on exam = OR 40.7 of IAI Ecchymosis = OR 15.8 Abrasions = OR 16.8 Based on other findings: Low blood pressure = OR 4.1 ALT >125, or AST >200 = OR 17.4 UA showing >5RBC/hpf = OR 4.8 Abdominal Trauma3 Repeat abdominal exams cornerstone of diagnosis Abdominal Trauma3 If unstable vitals, indication for OR FAST to look for free fluid in the abdomen, which may indicate the presence of intraabdominal bleeding. IV contrast enhanced CT gold standard for diagnosis of stable patient Definitive management dependant upon specific organ injured Burns/Thermal Injury Burns/Thermal Injury3,13,29 70% pediatric burns secondary to hot liquid Up to 20% burns in younger children secondary to abuse or neglect Consider inhalational injury and need for EARLY intubation if not secondary to liquid Hoarseness Black sputum Facial burn Accident in closed area Burns 13,30 Burn Assessment Depth 1st degree: superficial (epidermis) 2nd degree: superficial or deep partial thickness (dermis) 3rd degree: full thickness (beyond dermis) http://www.unboundedmedicine.com/pics/burn.jpg Burns 4th degree: involves underlying subcutaneous tissue, tendon, bone Burn/Thermal Injury 13,22 Burn Assessment Time to healing Appearance Surface Sensation 1st degree Pink or red Dry Painful Days Superficial 2nd degree Pink, clear blisters Moist Painful 14–21 days Deep 2nd degree Pink, hemorrhagic blisters, red Moist Painful Weeks, or may progress to 3rd degree and require graft 3rd degree White, brown Dry, leathery Insensate Requires excision 4th degree Brown, charred Dry Insensate Requires excision Burn/Thermal Injury 3,13 Estimating Burn Size Palm of patient’s hand = ~ 1% BSA Burn/Thermal Injury: Management3 ABCDE’s Consider early intubation if airway involvement Tetanus prophylaxis and ANALGESIA Fluid resuscitation mainstay of treatment Parkland Resuscitation Formula: using Ringer’s Lactate Give 4ml/kg/%TBSA First half of resuscitation fluids (AS WELL AS MAINTENANCE FLUIDS) over first 8 hours Second half over following 16 hours u/o goal: 1-2 ml/kg/hour Burn/Thermal Injury3 Pediatric Considerations: Electrolytes must be monitored closely Glucose should be added to maintenance fluids once resuscitation phase complete Albumin use during resuscitation phase not indicated, likely harmful Nutritional (enteral) support necessary and should begin within first 6 hours At risk for immunosuppression – However, no role for prophylactic antibiotics Burn/Thermal Injury3 Consider referral to a burn centre if: Inhalational injury Burn size >10% TBSA in child <10yo Burn size >20% in any patient Full-thickness burns >5% TBSA Burn involving hands/feet/face/perineum Mutiple comorbidities NAT Chemical/Electrical injury Submersion Injuries Submersion Injuries3,31,32 500 000 deaths due to drowning per year worldwide >50% drowning victims <5yo Fatality is highest in children <5yo M>F Most common cause of cardiac arrest in children Submersion Injury3,33 Most common sites of drowning: <1yo : Bathtubs (55%) 1 – 4yo : Pools (56%) >4yo : Freshwater (63%) Definition of drowning versus Near Drowning: Drowning = death within 24h of suffocation from submersion in liquid Near Drowning/Submersion injury = survival >24h past event Submersion Injury3 Pathophysiology of drowning: Accidental submersion Loss of normal breathing pattern Possible laryngospasm Pulmonary aspiration/breath-holding/apnea Hypoxemia: Low O2, hypercarbia, acidosis End-organ damage – circulatory arrest Submersion Injury3,34 ABCDE’s Consider early intubation Always consider C-spine immobilization 0.5% submersion victims have c-spine injury Remove wet clothing Treat hypothermia Poor Prognosis in Submersion Injury3,35 Prolonged submersion >25 minutes Delay in CPR initiation Resuscitation >25 minutes pH <7.1 Pulseless, cardiac arrest on arrival to emergency department Elevated blood glucose on arrival Dilated and fixed pupils on arrival Abnormal initial CT of brain Initial GCS of <5 Injury Prevention Injury Prevention3 90% injuries can be prevented Supervision and understanding child development critical in keeping them safe Injury Prevention3 Bike Helmets: If properly fitted can decrease risk of injury by 85%! Window Stops/Guards: Screens not effective barriers Smoke alarms: 3x greater risk of death in homes without them! Medication: Must be LOCKED and inaccessible Injury Prevention3 Carbon Monoxide Detectors: Install near sleeping areas Hot Water Temperature: Reduce tap temperature to <49oC Water Safety: SUPERVISION at ALL times Life jacket use 4 sided fencing for pools (1.2m high, selflatching gate) Injury Prevention3 Street Safety Children <9yo do not judge traffic safely Cannot determine how vehicles are moving Have underdeveloped peripheral vision Should NOT cross the road WITHOUT an ADULT Choking/Strangulation <4yo should not eat raw carrots, candies, popcorn, hotdogs, or have access to small toys Children should sleep in own crib, on their back, with well-fitted bedding to decrease risk of SIDS Conclusion Pediatric trauma and injury are preventable conditions Principles of management should always include a well orchestrated primary and secondary survey Never hesitate to admit for observation, ask for help or consult specialty services -the earlier the better. References 1. Resources for optimal care of the injured patient. Chicago: American College of Surgeons, Committee on Trauma; 1998:39-42. 2. Down DM, Keenan HT, Bratton SL. Epidemiology and prevention of childhood injuries. Crit Care Med 2002;30 No. 11:S385-392. 3. Mikrogianakis A, Valani R, Cheng A. Introduction. In: The Hospital for Sick Children Manual of Pediatric Trauma. 1st ed. Philadelphia: Lippincott Williams & Wilkins; 2008: 1-6. 4. Tintinalli, J. E., & Stapczynski, J. S. (2011). Tintinalli's emergency medicine: A comprehensive study guide. New York: McGraw-Hill. 5. Baker SP, O’Neill B, Ginsberg MJ, et al. (Eds.) Unintentional injury. In: The injury Fact Book. 2nd ed. New York: Oxford University Press; 1992:39-77. 6. Pomerantz WJ, Dowd MD, Buncher CR. Relationship between socioeconomic factors and severe childhood injuries. J Urban Health 2001; 78:141-151. 7. Durkin MS, Davidson LL, Kuhn, et al. Low-income neighborhoods and the risk of severe pediatric injury: A small area analysis of northern Manhattan. Am J Public Heatlh 1994; 84:587-92. 8. Champion HR, Sacco WJ, Copes NW, et al. A revision of the trauma score. J Trauma 1989;29:623-629. 9. Tepas JJIII, Mollitt DL, Talbert JL, et al. The pediatric trauma score as a predictor of injury severity in the injured child. J Pediatr Surg 1987;22:14-18. 10. Tepas JJ III, Ramenofsky ML, Mollitt DL, et al. The pediatric trauma score as a predictor of injury severity: an objective assessment. J Trauma 1988;28:425-429. 11. Marcin JP, Pollack MM. Triage scoring systems, severity of illness measures, and mortality prediction models in pediatric trauma. Crit Care Med 2002;30:S457-S467. 12. Scholer SJ, Hickson GB, Rjay WA. Sociodemographic factors identiy U.S. infants at high risk of injury mortality. Pediatrics 1999;102:1183-1188. References 13. Erbes, J (2011). Pediatric Trauma: Trends and Trauma Conference [Powerpoint slides]. Retrieved from http://www.wheatoniowa.org/webres/File/Trends%20in%20Trauma%20documents/Pediatric%20Trauma%20Presentation %20TNT%202011.ppt. 14. Agarwal S, Swanson S, Allison M et al. Comparing the utility of a standard pediatric resuscitation cart with a pediatrc resuscitation cart based on the broselow tape: a randomized controlled, crossover trial involving simulated resuscitation scenarios. Pediatrics 2005;116(3):e326-e333. 15. http://www.cps.ca/english/statements/cp/cp09-03.htm 16. http://www.resus.org.au/clinical_standards_for_resuscitation_march08.pdf 17. . American College of Surgeons Committee on Trauma. Advanced trauma life support for doctors. 7th ed. Chicago: American College of Surgeons;2005. 18. Keenan HT , Bratton SL. Epidemiology and outcomes of pediatric traumatic brain injury. Dev Neurosci 2006;28:256-263. 19. Sharples PM. Head injury in chlidren. In: Little RA, Platt W, eds. Injury in the young. Cambridge: Cambridge University Press; 1998:151-175. 20. Theissen ML, Woolridge DP. Pediatric minor closed head injury. Pediatr Clin North Am 2006;53:1–26. 21. Avarello JT, Cantor RM. Pediatric major trauma: an approach to evaluation and management. Emerg Med Clin NA 2007;25:803-836. 22. . Rosen, P., Marx, J. A., Hockberger, R. S., & Walls, R. M. (2009). Rosen's emergency medicine: Concepts and clinical practice. Edinburgh: Mosby. 23. Ped Emerg Care 2005;21:637-38 24. Emerg. Med. J. 2001;18;453-457 25. Eichelberger MR. Pediatric trauma: prevention, acute care, rehabilitation. St Louis: Mosby Year Book;1993. References 26. Sartorelli KH, Vane DW. The diagnosis and management of children with blunt injury of the chest. Semin Pediatr Surg 2004;13: 98-105. 27. Cotton BA, Beckert BW, Monica K, et al. The utility of clinical and laboratory data for predicting intra-abdominal injury among children. J Trauma 2004;56:1068-1075. 28. Holmes JF, Sokolove PE, Land C, et al. Identification of intra-abdominal injuries in children hospitalized following blunt torso trauma. Acad Emerg Med 1999;6:799-806. 29. Rossignol AM, Boyle CM, Locke JA et al. Hospitalized burn injuries in Massachusetts: an assessment of incidence and product development. Am J Public Health 1986;76;1341-1343. 30. http://www.unboundedmedicine.com/pics/burn.jpg 31. Peden MM, McGee K. The epidemiology of drowning worldwide. Inj Control Saf Promot 2003;10:195-199. 32. Quan L, Cummings P. Characteristics of drowning by different age groups. Inj Prev 2003;9:163-168. 33. Brenner RA, Trumble AC, Smith GS, et al. Where children drown, United States. Pediatrics 2001;108:85-89. 34. Watson RS, Cummings P, Quan L, et al. Cervical spinal injuries among submersion victims. J Trauma 2001;51:658-662. 35. Zuckerman GB, Conway EE. Drowning and near drowning: a pediatric epidemic. Pediatr Ann 2000;29:360-382. 36. http://www.who.int/violence_injury_prevention/child/injury/statistics/en/index.html Quiz Question 1 The purpose of the primary survey is to: Identify non-life-threatening issues so you know who to refer to. Identify immediately life-threatening issues and treat them. Identify what adjuncts such as CT, Xray series or bloodwork is needed. Undertake a complete head to toe exam and identify every issue the patient presents with. Quiz Question 2 Every trauma patient should arrive boarded and in C-spine precautions: True False Quiz Question 3 Relative contraindications of the use of the intraosseous needle include all except: 1. 2. 3. 4. 5. Underlying fracture Overlying infection Previous attempt at same site Osteogenesis Imperfecta Unstable vital signs Quiz Question 4 CPP is best described by which relationship: 1. 2. 3. 4. CPP = MAP – ICP CPP = MAP + ICP MAP = CPP – ICP ICP = MAP x CPP Quiz Question 5 What percentage of injuries in children are preventable? 1. 2. 3. 4. None of them, children are unpredictable. Around 10% Between 15-130% >90%