Cardiac applications of 16 slice MDCT :Initial experience Samsung Medical Center Dong-Joon Ahn Purpose • Applications of 16 slice MDCT in cardiac disease • To evaluate the effectiveness : CAC , CTA , Functional analysis Materials & Equipments • CAC : 8 , CTA : 28 • Lightspeed ultra 16 (GE) • Advantage workstation version 4.0 (GE) • Millenia 3500 CT ECG monitoring system (Invivo rsearch Inc.) • Envision CT (Medrad) • Iomeron 300 (Braco co.) Method Calcium scoring I. Image acquisition – No contrast material – 2.5mm x 8i scan (cine mode) – Gantry rotation time : 0.5sec – Prospective ECG gating : 75% II. Evaluation – Agatstone score Method Coronary arteries angiography I. Image acquisition – Non-ionic CM 120 - 150ml, 4ml/s – 0.625mm scan – Gantry rotation time : 0.5sec – Retrospective ECG gating – Image reconstruction according to cardiac phases : 5 - 95% of RR interval II. Evaluation – Compare 45%, 55% & 75% of RR interval Reconstruction method & heart rate HR Acquisition Mode Temporal Resolution 40~60 Snapshot Segment 250ms, 1cycle 60~75 Snapshot Burst 125ms, 2cycles 75~90 Snapshot Burst 65ms, 4cycles Plus Reconstruction method Snapshot segment mode Snapshot burst mode Snapshot burst plus mode Method Post processing methods • Volume rendering • Maximum intensity projection (MIP) • Reformation in cardiac short and long axis • Vessel analysis • Endoscopic view (fly-through) • Curved reformation Results I. Calcium scoring Agatscore 0 in 4 14 in 1 55 in 1 821 in 1 928 in 1 Results II.Coronary arteries angiography • Best phase locations for image quality – 45% : RCA in 7, distal LAD in 5 – 55% : RCA in 1 – 75% : LAD in most patients and RCA in 2 • good image quality in 33/36 (91%) LAD: 75% = Best 45% 55% 75% Phase location and image quality 45% 55% 65% 75% Short and long axis of heart Volume rendering LIMA - SVG Coronary vessel tree view Artifact Automatic MIP Curved reformation MPVR Consideration • Improved image reconstruction algorithm and software • Prospective or retrospective ECG gating • Better temporal resolution • Image acquisition of isotropic resolution Limitations of coronary CTA • Extensive calcifications • Stents : spatial resolution • Variable heart rate : poor image quality • Radiation dose • Small branches / septal branches Conclusion (I) – Screening asymptomatic high risk population (CAC, CTA) – Exclusion of stenosis in patients with low likelihood of extensive disease – Diagnosis in pts with atypical angina – Post-procedural evaluation (CABG, stent) – Plaque characterization – Follow-up after drug treatment Conclusion (II) • The fast volume coverage of ECG gated 16 slice CT enables acquisition of the entire heart volume with nearly isotropic resolution within a single breath hold. Hr 100-105 Cardiac CT • EKG 동조화 • Temporal resolution 향상 • Isotropic resolution영상획득 • Software Cardiac function Short and long axis of heart Phase registration Before After Vessel analysis Volume rendering Isotropic resolution영상획 득 RCA Stent HR = 75-47-75 Y- graft :RITA-LAD, RITA-OM1-OM2-PL 45% volume rendering, HR: 75-84