Osteoarthritis of the Hand Andy Ballantyne Edinburgh SpR Rotation What is Osteoarthritis? OA is a disturbance of the normal balance of degradation and repair of articular cartilage and subchondral bone 40% Adult Population Affected 10% Require Medical Treatment 1% Disabled Multifactorial Aetiology Age Sex Genetics Trauma Occupation Race Incidence of OA of the Hand Commonest form of OA <40 yrs - 50 new cases per 1000 personyears at risk 40 - 59 yrs - 65 new cases per 1000 personyears at risk >60 yrs - 110 new cases per 1000 personyears at risk (Kallman et al. 1990, Arth Rheum 33,1323 - 1332) Pattern of Joint Involvement Framingham OA Most commonly affected Study, Boston - 746 joints subjects, 1967 - 1993 DIPJ Chingford Study - 1st CMC 967 female subjects PIPJ Baltimore MCPJ Longitudinal Study of Ageing 177 male subjects, serial hand Xrs Others - Sesamoid, Trapezial Scaphoid/trapezoid, Pisiform-triquetral OA Pattern of Joint Involvement Generalised OA of the Hand - clustering of joint involvement (Chaisson 1997, Framingham Study) Prevalent OA in one joint increased the incidence risk of OA in : other joints in same row other joints in same ray OA in DIPJ or PIPJ increased incidence risk of OA in any other hand joint. Thumb CMC not a strong predictor of generalised disease Pattern of Joint Involvement Polyarticular subset of hand OA (Egger 1995, Chingford study) Major determinants of pattern of involvement symmetry clustering by row clustering by ray Clinical Features Fingers Swelling around joints Lateral deformity Osteophytes/exostoses Heberdens Nodes -” little hard knobs the size of a small pea, particularily a little below the top, near the joint” (Heberden 1710-1801) Bouchards Nodes Mallet Finger Mucous Cysts/Ganglion hyaluronic acid filled cysts Clinical Features Thumb CMC Subluxation of the CMC - metacarpal base prominence Z-deformity - bony collapse at the MC base leads to adduction of the MC and hyperextension of the MCP Examination Thumb CMC PIPJ/DIPJ Tenderness at joint line Lateral Instability Pain on Axial Compression Crepitus on Axial Compression Reduced Range of Movement Tenderness over 1stCMC Pain and Crepitus on Axial Compression - torque test Decreased Pinch Strength Subluxation - intermittent pressure to MC base while pat pinches Sesamoid Arthritis Pain palmar plate at thumb MCP Good joint space Elicited by press. on palmar plate Radiological Features 88% Joint Space Narrowing 81% Osteophytes 46% Subchondral Sclerosis 33% Bony Cysts <20% Lateral Joint Deformity <20% Cortical Collapse (Kallman 1989, Arth Rheum 32, 1584-1591) Radiological Classification Kellgren and Lawrence Scale (1957) Ann Rheum Dis 16:494 - 501 Kallman (1989) Arth Rheum 32:1584 1591 Dell (1978) - 1st CMC OA Kellgren/Lawrence Scale (1957) 0 No Osteophytes 1 Doubtful osteophytes 2 Minimal osteophytes, possibly with narrowing,cysts and sclerosis 3 Moderate or definite osteophytes with moderate joint space narrowing 4 Severe with large osteophytes and definite joint space narrowing Kallman (1989) Osteophytes 0 = none 1 = small 2 = moderate 3 = large Joint space narrowing 0 = none 1 = definitely narrowed 2 = severely narrowed 3 = joint fusion Subchondral sclerosis 0 = absent 1 = present Subchondral cysts 0 = absent 1 = present Lateral deformity 0 = absent 1 = present Collapse of Central joint Cortical Bone 0 = absent 1 = present Dell (1978) Stage I Stage II Mild joint narrowing or subchondral sclerosis. Mild joint effusion or ligament laxity. No subluxation or osteophyte formation Narrowing the CMC and sclerosis. Ulnar osteophytes. Subluxation radially and dorsally Stage III Further narrowing, cystic change and sclerosis. Passive reduction of subluxation not possible. Scaphotrapezial joint may show arthrosis Stage IV As above, more severe. CMC may be immobile and pain free Treatment Options for OA of the Hand Non surgical Splints NSAIDs Intraarticular Injections Surgical Stabilisation Arthrodesis Arthroplasty Surgery for Hand OA 1st CMC DIPJ PIPJ MCPJ other procedures Surgery for the 1st CMC Anatomical considerations Palmar/Ulnar collateral ligament Dorsal intermetacarpal ligament Laxity leads to subluxation Congenital laxity - Ehlos Danlos early OA changes Surgery for the 1st CMC Radiological Considerations Involvement of other trapezial joints 86% 2nd metacarpal 48% scaphoid 35% trapezoid Pattern of joint involvement influences choice of procedure Indications for Surgical Intervention Failure of non-surgical methods pain instability - weakness in grip In the presence of OA change Keelgren/Lawrence >2 Arthrodesis of the 1st CMC Disease limited to CMC positioned 45o palmar and radial abduction cup and cone arthrodesis - 2-5% non-union Arthroplasty of the 1st CMC Trapezium excision arthroplasty ?fascia/tendon interposition ?ligament reconstruction ??silicone interposition arthroplasty Total Joint Arthro. Hemiarthroplasty Soft Tissue interposition or Ligament Reconstruction? Burton & Pellegrini, 1986 (J Hand Surg) - Lig. recon and tendon interposition - improved grip strength and endurance Gerwin 1997 (Clin Orthop) -lig. recon. no tendon interposition - no requirement for tendon interposition Livesey 1996 (J Hand Surg) - lig. recon. produces stronger hand than trapezial excision alone, although slower recovery Surgery for the DIPJ Indications Pain Instability Mucous Cyst Deformity Options ~80% presenting are at a stage requiring surgery to alleviate symptoms Arthrodesis Arthroplasty Procedures for Symptom Relief Arthrodesis of the DIPJ only treatment in the presence of significant bone destruction and instability multiple methods to obtain arthrodesis - cup and cone, K-wires 2% pseudoarthrosis (Carroll 1969, JBJS - 635 joints) Surgery for the DIPJ Interposition Arthroplasty silicone interposition preserves motion and stability falling into disfavour Wilgis 1997 (Clin Orthop) - 38 digits, <10% implants removed Synovectomy and osteophytectomy stable joint with good bone preservation Mucous Cyst Excision Surgery for the PIPJ Indications Pain Instability Deformity In the presence of OA Arthrodesis Arthroplasty cemented silicone interposition Pelligrini 1990, J Hand Surg - 24 pat Cemented Biomeric - failed average 2.25yrs Silicone - 35% showed bone resorption Arthrodesis - greatest improvement in lat grip MCP/IPJ Thumb Arthrodesis - either IPJ or MCP Interpositional Arthroplasty - MCP Cemented Steffee prosthesis -slotted component Swanson Silicone Rubber Arthroplasty Soft Tissue Arthroplasty salvage procedures Surgical Procedures for Other Joints MCPJ Soft tissue Arthroplasty Joint Replacement Arth. Steffee Prosthesis Ball and Socket joints Sesamoid OA excision of the sesamoid Pisotriquetral OA injection pisiform excision Summary of Surgical Treatment 1st CMC - Trapezial excisional arthro. DIPJ - Arthrodesis PIPJ - unresolved DIPJ - ?Silicone Interpositional Arthroplasty Hand Osteoarthritis Common problem affecting elderly females Most commonly affects DIPJ & 1st CMC Surgical Intervention for pain and instability Number of unresolved questions regarding surgical treatment - i.e.. Type of arthroplasty Outcome - painfree but with reduced ROM and decreased pinch strength